Title: Lewis and Clark Interpretive Center in St. Louis - Tours and Activities | Expedia.ca [Lewis and Clark Interpretive Center Hotels](https://expedia.ca/Lewis-And-Clark-Interpretive-Center-Hotels.0-l6285389-0.Travel-Guide-Filter-Hotels)[Flights to St. Louis](https://expedia.ca/Cheap-Flights-To-St-Louis.d178309.Travel-Guide-Flights)[Things to do in St. Louis](https://expedia.ca/Things-To-Do-In-St-Louis.d178309.Travel-Guide-Activities)[Lewis and Clark Interpretive Center Car Rentals](https://expedia.ca/Car-Rentals-In-Lewis-And-Clark-Interpretive-Center.d6285389.Car-Rental-Guide)[St. Louis Vacation Packages](https://expedia.ca/St-Louis.d178309.Destination-Travel-Guides) # Lewis and Clark Interpretive Center Tours and Activities ## Visit Lewis and Clark Interpretive Center Activities [St. Louis travel guide](https://expedia.ca/St-Louis.dx178309) --- --- ## Plan a trip to see Lewis and Clark Interpretive Center Price found within the past 48 hours. Click for updated prices. ![Hampton Inn & Suites Clayton/St. Louis-Galleria Area](https://images.trvl-media.com/lodging/1000000/20000/17600/17599/ff4ffddd_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hampton Inn & Suites Clayton/St. Louis-Galleria Area Clayton CA $812 per person Apr 3 - Apr 5 found 13 hours ago Roundtrip flight included Toronto (YYZ) to St. Louis (STL) 9/10 Wonderful! (894 reviews) Friendly staff, enjoyed our stay. Reviewed on Feb 22, 2026 ![Spacious 3-Bedroom with King Bed](https://images.trvl-media.com/lodging/110000000/109680000/109680000/109679988/f2203ae1_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Spacious 3-Bedroom with King Bed Central West End CA $1,203 per person Apr 3 - Apr 5 found 13 hours ago Roundtrip flight included Toronto (YYZ) to St. Louis (STL) 8.6/10 Excellent! (10 reviews) Clean room nice area Reviewed on Feb 1, 2026 ![Hotel Saint Louis, Autograph Collection](https://images.trvl-media.com/lodging/28000000/27480000/27478600/27478599/8a12cc18_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Saint Louis, Autograph Collection Downtown St. Louis CA $865 per person Apr 3 - Apr 5 found 13 hours ago Roundtrip flight included Toronto (YYZ) to St. Louis (STL) 8.8/10 Excellent! (458 reviews) Not the best and not the Reviewed on Feb 24, 2026 ### Popular places to visit ![Lewis and Clark Confluence Tower which includes views](https://images.trvl-media.com/place/553248621532648630/065ee1ef-2409-451c-b11d-1ba274909a3b.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Lewis and Clark Confluence Tower Bring a camera when you climb this tower, which offers fantastic views across the Mississippi River and provides insight into a fascinating piece of history. [](https://expedia.ca/Lewis-And-Clark-Confluence-Tower-Hartford.d553248621532648630.Vacation-Attraction) #### Lewis and Clark State Memorial Park Explore the great outdoors at Lewis and Clark State Memorial Park, a lovely green space in Hartford. Discover the area's museums and monuments. [](https://expedia.ca/Lewis-And-Clark-State-Memorial-Park-St-Louis.d911403821536997376.Vacation-Attraction) #### Hartford Park After visiting Hartford Park, make a plan to see the other sights and activities in Hartford. Discover the area's museums and monuments. [](https://expedia.ca/Hartford-Park-Hartford.d911404232178233344.Vacation-Attraction) #### Hartford City Hall Hartford City Hall is just one of the places to see in Hartford, so why not enjoy the other things to explore during your travels? Amble around the area's riverfront or experience its museums. [](https://expedia.ca/Hartford-City-Hall-Hartford.d911406494470467584.Vacation-Attraction) #### Jones-Confluence Point State Park You can take time to visit Jones-Confluence Point State Park during your travels to West Alton. You can attend a sporting event while in the area. [](https://expedia.ca/Jones-Confluence-Point-State-Park-West-Alton.d553248621532648631.Vacation-Attraction) #### Dads Club Park Explore the great outdoors at Dads Club Park, a lovely green space in South Roxana. [](https://expedia.ca/Dads-Club-Park-South-Roxana.d911404787942391808.Vacation-Attraction) --- ## Best Lodging Options Near Lewis and Clark Interpretive Center ## Check availability on hotels close to Lewis and Clark Interpretive Center [Tonight ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6285389&startDate=2026-03-02&endDate=2026-03-03)[Mar 2 - Mar 3](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6285389&startDate=2026-03-02&endDate=2026-03-03) [Tomorrow night ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6285389&startDate=2026-03-03&endDate=2026-03-04)[Mar 3 - Mar 4](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6285389&startDate=2026-03-03&endDate=2026-03-04) [This weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6285389&startDate=06%2F03%2F2026&endDate=08%2F03%2F2026)[Mar 6 - Mar 8](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6285389&startDate=06%2F03%2F2026&endDate=08%2F03%2F2026) [Next weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6285389&startDate=13%2F03%2F2026&endDate=15%2F03%2F2026)[Mar 13 - Mar 15](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6285389&startDate=13%2F03%2F2026&endDate=15%2F03%2F2026) ![21C Museum Hotel St Louis ](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/cd6b7758_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### 21C Museum Hotel St Louis 1528 Locust street St. Louis MO [](https://expedia.ca/St-Louis-Hotels-21C-Museum-Hotel-St-Louis.h89164592.Hotel-Information) ![Pear Tree Inn St. Louis Near Union Station](https://images.trvl-media.com/lodging/1000000/30000/26600/26572/0bb9dbf3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Pear Tree Inn St. Louis Near Union Station 2211 Market Street St. Louis MO [](https://expedia.ca/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Near-Union-Station.h26572.Hotel-Information) ![Drury Plaza Hotel St. Louis at the Arch](https://images.trvl-media.com/lodging/1000000/550000/546300/546271/78b2a688_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Plaza Hotel St. Louis at the Arch 2 South 4th Street St. Louis MO [](https://expedia.ca/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-At-The-Arch.h546271.Hotel-Information) ![Hyatt Regency St. Louis at The Arch](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/335a172e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hyatt Regency St. Louis at The Arch 315 Chestnut St St. Louis MO [](https://expedia.ca/St-Louis-Hotels-Hyatt-Regency-St-Louis-At-The-Arch.h14877.Hotel-Information) ![Magnolia Hotel St. Louis, a Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/4b87c2a3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Magnolia Hotel St. Louis, a Tribute Portfolio Hotel 421 N 8th St St. Louis MO [](https://expedia.ca/St-Louis-Hotels-Magnolia-Hotel-St-Louis.h8131949.Hotel-Information) ![Marriott St. Louis Grand](https://images.trvl-media.com/lodging/1000000/910000/904800/904712/4c313173_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Marriott St. Louis Grand 800 Washington Ave St. Louis MO [](https://expedia.ca/St-Louis-Hotels-Marriott-St-Louis-Grand.h904712.Hotel-Information) ![Home2 Suites by Hilton St. Louis Downtown](https://images.trvl-media.com/lodging/77000000/76520000/76510800/76510729/104b5741_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Home2 Suites by Hilton St. Louis Downtown 1221 Locus Street St. Louis MO [](https://expedia.ca/St-Louis-Hotels-Home2-Suites-St-Louis-Downtown.h76510729.Hotel-Information) ![Live by Loews - St.Louis](https://images.trvl-media.com/lodging/40000000/39170000/39161300/39161277/4c39e93f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Live by Loews - St.Louis 799 Clark ave St. Louis MO [](https://expedia.ca/St-Louis-Hotels-Live-By-Lowes-StLouis.h39161277.Hotel-Information) ![Courtyard by Marriott St. Louis Downtown/Convention Center](https://images.trvl-media.com/lodging/1000000/850000/848500/848402/b44eefea_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Courtyard by Marriott St. Louis Downtown/Convention Center 823-827 Washington Avenue St. Louis MO [](https://expedia.ca/St-Louis-Hotels-Courtyard-By-Marriott-St-Louis-DowntownConvention-Center.h848402.Hotel-Information) [See all 2,031 properties in Lewis and Clark Interpretive Center](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=6285389) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=DX_POI_Spring_PROMO_6285389)