Title: Isla Grande Vacation Packages & Trips 2026 from CA $1,381 | Expedia.ca

[Hotels in Isla Grande](https://expedia.ca/Isla-Grande-Hotels.d6053183.Travel-Guide-Hotels)[Vacation Rentals in Isla Grande](https://expedia.ca/Isla-Grande-Vacation-Rentals.d6053183.Travel-Guide-VacationRentals)[Flights to Isla Grande](https://expedia.ca/Cheap-Flights-To-Isla-Grande.d6053183.Travel-Guide-Flights)[Isla Grande Car Rentals](https://expedia.ca/Car-Rentals-In-Isla-Grande.d6053183.Car-Rental-Guide)

![](https://images.trvl-media.com/place/6053183/8bba6d27-3102-43e6-89e4-9ef59409f2b6.jpg?impolicy=fcrop&w=1200&h=300&q=medium)

# Isla Grande Vacation Packages

## Book a Hotel + Flight or Car together to unlock savings

- ##  
Plan, book, travel with confidence
- ###  
Better together  
Save up to CA $1,096 when you book a flight and hotel together\*
- ###  
Find the right fit  
With over 300,000 hotels worldwide, it's easy to create a perfect package
- ###  
Rest easy  
Plan, book, and manage your trip all in one place

#### Your Isla Grande Vacation

With a Isla Grande vacation package, say goodbye to endless planning and hello to stress-free adventure. Every detail of your getaway has been taken care of before you go, so you can enjoy each moment discovering this lively city. If taking in the sights is a priority during your trip to Isla Grande, be sure to swing by famous attractions like [Isla Mamey](https://www.expedia.ca/Isla-Mamey-Colon.d553248623454093160.Vacation-Attraction) and [Portobelo National Park](https://www.expedia.ca/Portobelo-National-Park-Colon.d6252836.Vacation-Attraction). Whoever you're heading away with and whatever you want to spend, your dream Isla Grande vacation is just a few clicks away with Expedia.

## Top Isla Grande Vacation Deals

Price found within the past 48 hours. Click for updated prices.

![Villa Botero By Casa Mojito B&B](https://images.trvl-media.com/lodging/12000000/11930000/11927200/11927153/393d35f8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Villa Botero By Casa Mojito B&B

CA $1,381

per person

Mar 1 - Mar 8

found 1 day ago

Roundtrip flight included

Ottawa (YOW) to Panama City (PTY)

9.8/10 Exceptional! (60 reviews)

Host was excellent. Great communication and very helpful. The rooms were nice and great value.

Reviewed on Apr 18, 2025

![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Central Hotel Panama Casco Viejo

Casco Viejo

CA $2,139

per person

Mar 1 - Mar 8

found 1 day ago

Roundtrip flight included

Ottawa (YOW) to Panama City (PTY)

9/10 Wonderful! (1,002 reviews)

Excellent hotel , good breakfast, great location, would highly recommend

Reviewed on Dec 7, 2025

![Central Hotel Bocas del Toro](https://images.trvl-media.com/lodging/115000000/114670000/114666400/114666306/6a7feca7_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Central Hotel Bocas del Toro

CA $2,077

per person

Feb 12 - Feb 16

found 1 hour ago

Roundtrip non-stop flight included

Toronto (YTO) to Panama City (PTY)

No reviews

![Villa Marina Lodge & Condos](https://images.trvl-media.com/lodging/10000000/9550000/9542300/9542280/8ba948e1_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Villa Marina Lodge & Condos

CA $1,436

per person

Feb 15 - Feb 22

found 1 day ago

Roundtrip non-stop flight included

Toronto (YTO) to Panama City (PTY)

9/10 Wonderful! (133 reviews)

Love that this property is at the other end of the beach from the late night partying. Walkable beach. Great restaurants nearby. The property was adding coffee makers and mini fridges the day we were leaving. Great staff, restaurant and drinks. We’ve been twice with our pooches. Will be back

Reviewed on Jul 14, 2025

![MARINN PLACE Financial District](https://images.trvl-media.com/lodging/91000000/90810000/90801900/90801879/c11e781a_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### MARINN PLACE Financial District

Bella Vista

CA $1,964

per person

Feb 20 - Feb 27

found 1 day ago

Roundtrip flight included

Ottawa (YOW) to Panama City (PTY)

9.2/10 Wonderful! (298 reviews)

Second stay, very nice

Reviewed on Nov 7, 2025

## Ready to book your vacation to Isla Grande?

Choose your dates

## Isla Grande Hotel Deals

![Ordovician Beach Resort](https://images.trvl-media.com/lodging/104000000/103770000/103761600/103761591/4a052041_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Ordovician Beach Resort

Isla Grande Isla Grande Colon

10/10 Exceptional! (3 reviews)

Amazing piece of Caribbean paradise! The staff went above and beyond to make us feel special.

Reviewed on Sep 5, 2025

[Get rates](https://expedia.ca/Hotel-Search?startDate=24%2F12%2F2025&endDate=25%2F12%2F2025&selected=103761591&PinnedHotelID=103761591&HadPinnedHotel=true&regionId=6053183)

[](https://expedia.ca/Hotel-Search?startDate=24%2F12%2F2025&endDate=25%2F12%2F2025&selected=103761591&PinnedHotelID=103761591&HadPinnedHotel=true&regionId=6053183)

![HOTEL ISLA GRANDE ](https://images.trvl-media.com/lodging/120000000/119950000/119947200/119947185/9e6abf31_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

HOTEL ISLA GRANDE 

Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province

Fully refundableReserve now, pay when you stay

CA $129

CA $143 total

Dec 15 - Dec 16

includes taxes & fees

5/10 (4 reviews)

Although I gave this hotel a medium rating I enjoyed myself. This is a rough almost close to camping hotel. I must have not seen the message about bringing soap wash clothes, hand towel, tissue actually everything. The water does not get cold and there was a party set up just outside the window lasting ...

Reviewed on Sep 19, 2025

[](https://expedia.ca/Hotel-Search?startDate=15%2F12%2F2025&endDate=16%2F12%2F2025&selected=119947185&PinnedHotelID=119947185&HadPinnedHotel=true&regionId=6053183)

![Hotel Cocotal](https://images.trvl-media.com/lodging/117000000/116790000/116790000/116789972/c828cfe9_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Hotel Cocotal

La Guaira Isla Grande Provincia de Colón

Fully refundableReserve now, pay when you stay

CA $62

CA $129 total

Dec 11 - Dec 12

includes taxes & fees

10/10 Exceptional! (2 reviews)

It was old, quaint interesting, would recommend

Reviewed on Sep 5, 2025

[](https://expedia.ca/Hotel-Search?startDate=11%2F12%2F2025&endDate=12%2F12%2F2025&selected=116789972&PinnedHotelID=116789972&HadPinnedHotel=true&regionId=6053183)

[See all 54 properties in Isla Grande](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=11%2F12%2F2025&endDate=12%2F12%2F2025&regionId=6053183)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

All Inclusive Vacations

[](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Beach Vacations

[](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Family Vacations

[](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Golf Vacations

[](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Luxury Vacations

[](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Romantic Vacations

[](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Ski Vacations

[](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click)

## Explore a world of travel with Expedia

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- Vacation Rental

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- [Playa Chiquita Hotels ](https://www.expedia.ca/Playa-Chiquita-Hotels.d553248635975847835.Travel-Guide-Hotels)
- [Cheap Hotels in Portobelo ](https://www.expedia.ca/Portobelo-Hotels-Cheap-Hotels.0-0-d6145607-tCheapHotels.Travel-Guide-Filter-Hotels)
- [Portobelo Hotels ](https://www.expedia.ca/Portobelo-Hotels.d6145607.Travel-Guide-Hotels)
- [Puerto Lindo Hotels ](https://www.expedia.ca/Puerto-Lindo-Hotels.d3000007427.Travel-Guide-Hotels)

- [Flights to Maria Chiquita ](https://www.expedia.ca/Cheap-Flights-To-Maria-Chiquita.d6344217.Travel-Guide-Flights)
- [Flights to Portobelo ](https://www.expedia.ca/Cheap-Flights-To-Portobelo.d6145607.Travel-Guide-Flights)

- [Isla Mamey ](https://www.expedia.ca/Isla-Mamey-Colon.d553248623454093160.Vacation-Attraction)
- [Palenque Vacations ](https://www.expedia.ca/Palenque.d553248623282267036.Destination-Travel-Guides)
- [Portobelo Vacations ](https://www.expedia.ca/Portobelo.d6145607.Destination-Travel-Guides)
- [Visit Puerto Pilón ](https://www.expedia.ca/Puerto-Pilon.dx829297941343653888)

- [Car rental Miramar ](https://www.expedia.ca/Car-Rentals-In-Miramar.d553248623282266307.Car-Rental-Guide)

- [Puerto Lindo Vacation Rentals ](https://www.expedia.ca/Puerto-Lindo-Vacation-Rentals.d3000007427.Travel-Guide-VacationRentals)
- [Salamanca Vacation Rentals ](https://www.expedia.ca/Salamanca-Vacation-Rentals.d829297957902774272.Travel-Guide-VacationRentals)

\* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.

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