Isla Grande Vacation Packages
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to CA $4,200 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Isla Grande Vacation
With a Isla Grande vacation package, say goodbye to endless planning and hello to stress-free adventure. Every detail of your getaway has been taken care of before you go, so you can enjoy each moment discovering this lively city. If taking in the sights is a priority during your trip to Isla Grande, be sure to swing by famous attractions like Isla Mamey and Portobelo National Park. Whoever you're heading away with and whatever you want to spend, your dream Isla Grande vacation is just a few clicks away with Expedia.
Top Isla Grande Vacation Deals
Price found within the past 48 hours. Click for updated prices.
Central Hotel Panama Casco Viejo
Casco Viejo
Price was CA $4,832, price is now CA $2,915 per person
CA $2,915
per person
Jul 8 - Jul 15
found 1 day ago
Roundtrip non-stop flight included
Edmonton (YEG) to Panama City (PTY)
9.2/10 Wonderful! (1,009 reviews)
Wonderful location! Our room was right below the gym- we could hear weights being used. Luckily, the noise stopped by 10. The breakfast buffet was a great value and the food was very good
Reviewed on Apr 28, 2026
Casa Mallet by Wynwood House
Casco Viejo
Price was CA $3,913, price is now CA $2,846 per person
CA $2,846
per person
Jul 8 - Jul 15
found 1 day ago
Roundtrip non-stop flight included
Edmonton (YEG) to Panama City (PTY)
9.8/10 Exceptional! (27 reviews)
In the middle of the old town, lovely rooftop. Beautiful apartment. Easy check in. WhatsApp line is available if anything was needed or if we had questions.
Reviewed on Mar 12, 2026
Yoo by Wynwood House
Calidonia
Price was CA $3,346, price is now CA $2,485 per person
CA $2,485
per person
Jul 5 - Jul 12
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Panama City (PTY)
9.4/10 Exceptional! (6 reviews)
Unfortunately the name of the property was not Yoo by Wynwood. It is P. H. Yoo Panama & Arts Tower. This detail that was incorrect cost us time, money and stress at the beginning of our trip. We weren't able to get in touch with anyone at the property or at expedia and we ended up having to cross reference google photos to figure out the correct name and address of the location. This took us about an hour to do in a Country that we had never been to. We are very displeased with Expedia about this. We still have not been contacted by anyone.
Reviewed on Jul 26, 2025
Hilton Panama
Bella Vista
Price was CA $2,935, price is now CA $2,229 per person
CA $2,229
per person
Jun 6 - Jun 13
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
8.8/10 Excellent! (1,005 reviews)
This Hilton adheres to the best Hilton Standards- everything spot on.
Reviewed on Apr 24, 2026
Isla Grande Hotel Deals
Ordovician Beach Resort
Isla Grande Isla Grande Colon
The price is CA $612 per night from May 6 to May 7
CA $612
CA $681 total
May 6 - May 7
includes taxes & fees
10/10 Exceptional! (9 reviews)
The resort was outstanding. It exceeded expectations in every way. The service was the best we had in Panama. The cocktails were fun and the food was delicious and they have a vegan menu. We stayed in a king room and it was very private, pristine and well appointed.
Reviewed on Feb 21, 2026
HOTEL ISLA GRANDE
Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province
The price is CA $150 per night from May 4 to May 5
CA $150
CA $165 total
May 4 - May 5
includes taxes & fees
Hotel Cocotal
La Guaira Isla Grande Provincia de Colón
Fully refundableReserve now, pay when you stay
The price is CA $86 per night from May 3 to May 4
CA $86
CA $155 total
May 3 - May 4
includes taxes & fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Explore a world of travel with Expedia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
