Search Guest Houses in Southwest Houston from CA $65

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
Aug 29 - Aug 31
In two weeks
Sep 5 - Sep 7
In one month
Sep 19 - Sep 21
In two months
Oct 17 - Oct 19

Browse Select Southwest Houston Guest Houses

Our top choices for Southwest Houston guest houses

Cozy apartment/guest house near medical center
Interior

Cozy apartment/guest house near medical center

9.2 out of 10, Wonderful, (5)
"Host was amazing. Will definitely look to stay here again!"
The price is CA $65
CA $176 total
includes taxes & fees
Aug 24 - Aug 25
Cozy apartment/guest house near medical center
The Texas Bluebonnet - Garden and Spa w/ Fast Wi-Fi and Free Parking
Fridge, microwave, oven, stovetop

The Texas Bluebonnet - Garden and Spa w/ Fast Wi-Fi and Free Parking

10.0 out of 10, Exceptional, (3)
"Always enjoy staying here. "
The price is CA $135
CA $377 total
includes taxes & fees
Sep 1 - Sep 2
The Texas Bluebonnet - Garden and Spa w/ Fast Wi-Fi and Free Parking
Cozy Apartment near Downtown
Fridge, microwave, oven, stovetop

Cozy Apartment near Downtown

Cozy Apartment near Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Southwest Houston Hotel Reviews

Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

10/10 Excellent
"Have stayed here many time for treatments at MDA. "
Randy 2-night trip
Posted 20 hours ago
Hyatt Place Houston Medical Center