Title: Edisto Island Serpentarium in Edisto Island - Tours and Activities | Expedia.ca [Edisto Island Serpentarium Hotels](https://expedia.ca/Edisto-Island-Serpentarium-Hotels.0-l6335582-0.Travel-Guide-Filter-Hotels)[Flights to Edisto Island](https://expedia.ca/Cheap-Flights-To-Edisto-Island.d183937.Travel-Guide-Flights)[Things to do in Edisto Island](https://expedia.ca/Things-To-Do-In-Edisto-Island.d183937.Travel-Guide-Activities)[Edisto Island Serpentarium Car Rentals](https://expedia.ca/Car-Rentals-In-Edisto-Island-Serpentarium.d6335582.Car-Rental-Guide)[Edisto Island Vacation Packages](https://expedia.ca/Edisto-Island.d183937.Destination-Travel-Guides) # Edisto Island Serpentarium Tours and Activities ## Visit Edisto Island Serpentarium Activities --- --- ## Plan a trip to see Edisto Island Serpentarium Price found within the past 48 hours. Click for updated prices. ![The Francis Marion Hotel](https://images.trvl-media.com/lodging/1000000/50000/41300/41204/3ad3c4ea_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Francis Marion Hotel Charleston Historic District CA $1,208 per person Jun 4 - Jun 7 found 1 day ago Roundtrip non-stop flight included Toronto (YTO) to Charleston (CHS) 9/10 Wonderful! (2,167 reviews) The hotel’s location is ideal for exploring Charleston on foot—whether you’re shopping along King Street, dining at Husk or FIG, or taking photos around Rainbow Row. The rooms are spacious and clean, though the bathrooms feel slightly dated. Our room offered a great view of the bridge and the bay. The staff was consistently friendly and helpful. We would gladly stay here again. Reviewed on Mar 20, 2026 ![The Ryder Hotel](https://images.trvl-media.com/lodging/1000000/10000/4600/4544/d4e1e925_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Ryder Hotel Charleston Historic District CA $1,813 per person May 14 - May 17 found 1 day ago Roundtrip non-stop flight included Detroit (DTW) to Charleston (CHS) 8.6/10 Excellent! (1,024 reviews) Excellent location and such a fun, and cool hotel! We loved our stay there Reviewed on Mar 12, 2026 ![Andrew Pinckney Inn](https://images.trvl-media.com/lodging/1000000/110000/106200/106130/347a89fa_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Andrew Pinckney Inn Charleston Historic District CA $1,555 per person May 28 - Jun 1 found 17 hours ago Roundtrip non-stop flight included Ottawa (YOW) to Charleston (CHS) 9.6/10 Exceptional! (1,472 reviews) Yes, very clean & comfortable Courteous & knowledgeable staff Reviewed on Mar 20, 2026 ### Popular places to visit ![A very early morning outing at Botany Bay on Edisto Island. I had to start from my hotel at 3 AM to make it to this location before dawn. Botany Bay Plantation is a nature preserve and has regulated visitor hours. Gates open 30 minutes before sunrise - I wish they'd open a little sooner as the golden hour is pretty much more than half way done by the time one can make it to the beach. Nevertheless, it's a great location to visit at sunrise, especially if there are high clouds to add drama. Recommended to visit when the tide is ebbing as you then get the shadows of the trees, which to my eyes add more depth to the image. On this day, there was a bank of low clouds that prevented too much color but it was a great sunrise to witness nonetheless. The trees have so much character and add so much to the image. It's hard to look at the remnants of these trees and not imagine the onslaught they've withstood at the hands of mother nature. #WeekendGetAwayForTheFamily #colorful #USA #weekend #treetrove #blue](https://images.trvl-media.com/place/183937/a1bf3c70-2764-49ef-9be2-8437dc847a8b.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Botany Bay Plantation Explore the great outdoors at Botany Bay Plantation, a lovely green space in Edisto Island. Stroll along the beaches in this relaxing area, or seek out the fishing spots. [](https://expedia.ca/Botany-Bay-Plantation-Edisto-Island.d6335632.Vacation-Attraction) ![Watch the sunset from Kiawah Beachwalker Park, Kiawah Island, South Carolina. Kiawah is a golf-centered resort island with lots of palmettos, pine trees, and waterbirds. The dolphins practice "strand feeding" here, which is the act of herding the fish up on the beach along with a wave and wriggling up on the sand to retrieve them. #UStravel #travel #naturelovers #beach #sunset #Kiawah #SouthCarolina #RVlife #earthporn #goldenhour #camping #glamping #wanderlust #beachbound www.RVLuckyOrWhat.com](https://images.trvl-media.com/place/10856/43a529f7-0f7a-4f09-8066-03afbafb678c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Kiawah Beachwalker Park Explore the great outdoors at Kiawah Beachwalker Park, a lovely green space in Seabrook Island. Wander the beautiful beaches and seaside in this relaxing area. [](https://expedia.ca/Kiawah-Beachwalker-Park-Seabrook-Island.d6317714.Vacation-Attraction) #### With These Hands Gallery You can spend time browsing the exhibits at With These Hands Gallery during your travels in Edisto Island. Stroll along the beautiful beaches in this relaxing area, or seek out the biking trails. [](https://expedia.ca/With-These-Hands-Gallery-Edisto-Island.d553248621532654849.Vacation-Attraction) #### Botany Bay Plantation Heritage Preserve and Wildlife Management Area Explore the lovely green spaces of Botany Bay Plantation Heritage Preserve and Wildlife Management Area and enjoy the biking trails in Edisto Island. Wander the beautiful beaches in this relaxing area. [](https://expedia.ca/Botany-Bay-Plantation-Heritage-Preserve-And-Wildlife-Management-Area-Edisto-Island.d553248621532654847.Vacation-Attraction) #### Edisto Island Museum You can spend time studying the exhibits at Edisto Island Museum during your travels in Edisto Island. Wander the beautiful beaches in this relaxing area. [](https://expedia.ca/Edisto-Island-Museum-Edisto-Island.d6335580.Vacation-Attraction) #### Edisto Beach State Park You can take time to visit Edisto Beach State Park during your travels to Edisto Island. Wander the beautiful beaches in this relaxing area. [](https://expedia.ca/Edisto-Beach-State-Park-Edisto-Island.d6335576.Vacation-Attraction) --- ## Best Lodging Options Near Edisto Island Serpentarium ## Check availability on hotels close to Edisto Island Serpentarium [Tonight ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6335582&startDate=2026-03-21&endDate=2026-03-22)[Mar 21 - Mar 22](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6335582&startDate=2026-03-21&endDate=2026-03-22) [Tomorrow night ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6335582&startDate=2026-03-22&endDate=2026-03-23)[Mar 22 - Mar 23](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6335582&startDate=2026-03-22&endDate=2026-03-23) [Next weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6335582&startDate=27%2F03%2F2026&endDate=29%2F03%2F2026)[Mar 27 - Mar 29](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6335582&startDate=27%2F03%2F2026&endDate=29%2F03%2F2026) ![Beautiful Oceanfront 5 bedroom 5 1/2 bath home in Private Community.](https://images.trvl-media.com/lodging/108000000/107050000/107045500/107045499/a08a4600_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Beautiful Oceanfront 5 bedroom 5 1/2 bath home in Private Community. Edisto Island SC [](https://expedia.ca/Edisto-Island-Hotels-Beautiful-Oceanfront-Just-Built-5-Bedroom-5-12-Bath-Home-In-Private-Community.h107045499.Hotel-Information) ![Gorgeous Secluded Island W/Creek & Ocean View w/DOCK & swim! Pet-friendly/Wi-Fi](https://images.trvl-media.com/lodging/34000000/33510000/33502600/33502550/cda265b2_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Gorgeous Secluded Island W/Creek & Ocean View w/DOCK & swim! Pet-friendly/Wi-Fi Edisto Island SC [](https://expedia.ca/Edisto-Island-Hotels-Gorgeous-Secluded-Island-Wcreeks-Ocean-Views-Wdock-Pet-Friendlyfree-Wi-Fi.h33502550.Hotel-Information) ![Paradise Found- Stunning Ocean views + Unique Home](https://images.trvl-media.com/lodging/115000000/114280000/114273900/114273865/1f27c31d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Paradise Found- Stunning Ocean views + Unique Home Edisto Island SC [](https://expedia.ca/Edisto-Island-Hotels-Paradise-Found-Stunning-Ocean-Views-Unique-Home.h114273865.Hotel-Information) ![Gorgeous Oceanfront 6 bdrm, 6 ba. home, heated swim spa, elevator, private!](https://images.trvl-media.com/lodging/51000000/50630000/50625900/50625814/adb9c198_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Gorgeous Oceanfront 6 bdrm, 6 ba. home, heated swim spa, elevator, private! Edisto Island SC [](https://expedia.ca/Edisto-Island-Hotels-Gorgeous-Oceanfront-6-Bdrm.h50625814.Hotel-Information) ![Beach Access, Steps Away | Seaclusion by AvantStay](https://images.trvl-media.com/lodging/110000000/109960000/109958800/109958745/18480407_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Beach Access, Steps Away | Seaclusion by AvantStay Edisto Island SC [](https://expedia.ca/Edisto-Island-Hotels-Seaclusion-By-AvantStay-Walk-To-The-Beach.h109958745.Hotel-Information) ![Discover 5 Acres of Secluded Luxury on the Marsh and Close to the Beach: Edisto](https://images.trvl-media.com/lodging/103000000/102560000/102554800/102554763/287a39c6_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Discover 5 Acres of Secluded Luxury on the Marsh and Close to the Beach: Edisto Edisto Island SC [](https://expedia.ca/Edisto-Island-Hotels-Newly-Renovated-3BR-Edisto-Retreat-5-Acres.h102554763.Hotel-Information) ![The Marshpad, surrounded by nature, mins to beach in gated community ](https://images.trvl-media.com/lodging/100000000/99270000/99269600/99269583/aa3c81de_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Marshpad, surrounded by nature, mins to beach in gated community Edisto Island SC [](https://expedia.ca/Edisto-Island-Hotels-The-Marshpad.h99269583.Hotel-Information) ![Water Front Edisto with Private Dock On Deep Creek overlooking the Ocean](https://images.trvl-media.com/lodging/27000000/26940000/26930600/26930545/6286b1d3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Water Front Edisto with Private Dock On Deep Creek overlooking the Ocean Edisto Island SC [](https://expedia.ca/Edisto-Island-Hotels-Ocean-Front-And-Creek-Front-Edisto-With-A-Dock.h26930545.Hotel-Information) ![Low Country Home w/ Creek & Ocean views, dock, & indoor / outdoor living spaces](https://images.trvl-media.com/lodging/82000000/81160000/81155700/81155652/7df283b7_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Low Country Home w/ Creek & Ocean views, dock, & indoor / outdoor living spaces Edisto Island SC [](https://expedia.ca/Edisto-Island-Hotels-Low-Country-Home-W-Creek-Ocean-Views.h81155652.Hotel-Information) [See all 2,070 properties in Edisto Island Serpentarium](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=6335582) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.