Title: 5 Stars Hotels in Greenville, South Carolina from CA $280 - Find Cheap Greenville Hotels With 5 Stars | Expedia.ca [Greenville Travel Guide](https://expedia.ca/Greenville.dx1388)[Hotels in Greenville](https://expedia.ca/Greenville-Hotels.d1388.Travel-Guide-Hotels)[Vacation Rentals in Greenville](https://expedia.ca/Greenville-Vacation-Rentals.d1388.Travel-Guide-VacationRentals)[Flights to Greenville](https://expedia.ca/Cheap-Flights-To-Greenville.d1388.Travel-Guide-Flights)[Things to do in Greenville](https://expedia.ca/Things-To-Do-In-Greenville.d1388.Travel-Guide-Activities)[Greenville Car Rentals](https://expedia.ca/Car-Rentals-In-Greenville.d1388.Car-Rental-Guide)[Greenville Vacation Packages](https://expedia.ca/Greenville.d1388.Destination-Travel-Guides) ![Greenville featuring a city, a bridge and a river or creek](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63754-Greenville-Spartanburg.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 5 Stars Hotels in Greenville, South Carolina from CA $280 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Greenville 5 Star Hotels Tonight [Oct 26 - Oct 27](https://www.expedia.ca/Hotel-Search?regionId=1388&startDate=2025-10-26&endDate=2025-10-27&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 27 - Oct 28](https://www.expedia.ca/Hotel-Search?regionId=1388&startDate=2025-10-27&endDate=2025-10-28&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=1388&startDate=2025-10-31&endDate=2025-11-02&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=1388&startDate=2025-11-07&endDate=2025-11-09&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Greenville 5 Star Hotels ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Greenville-Hotels.s50-0-d1388.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Greenville-Hotels.s50-0-d1388.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Greenville. ![Grand Bohemian Lodge Greenville, Autograph Collection](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6a375dd3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Grand Bohemian Lodge Greenville, Autograph Collection 44 EAST CAMPERDOWN WAY, Greenville, SC CA $391 CA $442 total Nov 16 - Nov 17 includes taxes & fees 9.4/10 Exceptional! (394 reviews) [](https://expedia.ca/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ![The Westin Poinsett Greenville](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/3e47bf88_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Westin Poinsett Greenville 120 South Main St, Greenville, SC CA $265 CA $291 total Nov 23 - Nov 24 includes taxes & fees 9.2/10 Wonderful! (1,005 reviews) [](https://expedia.ca/Greenville-Hotels-The-Westin-Poinsett-Greenville.h575983.Hotel-Information) ![Hotel Hartness](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/7f5c10e6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Hartness 120 Halston Avenue, Greenville, SC CA $212 CA $280 total Nov 16 - Nov 17 includes taxes & fees 9.8/10 Exceptional! (605 reviews) [](https://expedia.ca/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) Still don't see what you're looking for? [See all properties in Greenville.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=27%2F10%2F2025&endDate=28%2F10%2F2025®ionId=1388&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=27%2F10%2F2025&endDate=28%2F10%2F2025®ionId=1388&star=50&star=50&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=27%2F10%2F2025&endDate=28%2F10%2F2025®ionId=1388&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=27%2F10%2F2025&endDate=28%2F10%2F2025®ionId=1388&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=27%2F10%2F2025&endDate=28%2F10%2F2025®ionId=1388&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=27%2F10%2F2025&endDate=28%2F10%2F2025®ionId=1388&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Greenville Falls Park on the Reedy offers a stunning urban oasis with waterfalls right in the heart of downtown. Bike the Swamp Rabbit Trail in the morning, then explore Main Street's locally-owned shops and farm-to-table restaurants by afternoon. [See all hotels in Greenville](https://www.expedia.ca/Hotel-Search?startDate=2025-11-09&endDate=2025-11-10&adults=2®ionId=1388) ![Greenville featuring a city, a bridge and a river or creek](https://images.trvl-media.com/place/1388/2f1c4846-4013-4641-a8dd-db2da5ca5774.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) Photo by Visit Greenville, South Carolina ## Top Greenville Hotel Reviews ## Find out more about Greenville ## Five Star Hotels in Greenville There's nothing wrong with enjoying the finer things in life. Indulge yourself on your next leisure time. After all, this is one of the Top 10 locations in Expedia's portfolio. You'll join the multitudes of vacationers who have made Greenville so fashionable in the last year. We should also mention, the hotels in this area receive outstanding marks for guest services, so you know you'll be looked after during your getaway. You deserve the great vacation you're dreaming about. Book one of Expedia's luxurious 5-star hotels in Greenville and get ready to be pampered like never before. #### Get a Great Deal on 5-Star Hotels in Greenville Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Excellent customer care, spacious rooms, and fabulous spa offerings are all on offer. We have a huge number of hotels in the region, and all of them offer outstanding amenities. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What kind of amenities will make your stay a wonderful one? A concierge to help you plan every detail of your day? A Swedish massage to help your cares fall away? Fluffy down pillows, piping hot coffees, and even space for your family pet in some cases...these hotels have it all. Want to see for yourself? Then explore the 31,943 reviews various guests have left on Expedia and get to know these places. Can't wait to get outside? We've got you covered. You'll find lots of attractions to see in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals—they're sure to have advice on what kind of excitement you can find in town. #### Make Your Escape to Greenville The results are in, and Greenville 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. This is a great time to find 5-star hotel deals in Greenville! Don't put off your dream vacation any longer. Choose one of the 5-star hotels in Greenville today and settle down in the lap of luxury tomorrow. ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Greenville? > How much you pay for a 5-star hotel in Greenville depends on things such as when you want to go and the length of your trip. A top tip for bagging the best deal? Use our pricing filters to check out the available accommodations for your chosen dates. > > > > - Search for the lowest price per night from CA $280 ### What makes a hotel 5 stars in Greenville? > From gourmet dining venues and all-day fitness centres to pools and luxury bedding, the 5-star experience in Greenville is all about luxury and relaxation. But it calls for more than just upscale amenities to earn a 5-star rating. Hotels also have to deliver outstanding guest-focused services like in-room massage treatments, dry cleaning and laundry and a nightly turn-down service. ### Are there any 5-star all-inclusive resorts in Greenville? > Use Expedia's filter tool to find a luxury getaway in Greenville where most of what you need is included. From there, refine your results for accommodations that have 5 stars and are categorized as "All inclusive." The main thing on the itinerary at these stays? 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Spartanburg](https://www.expedia.ca/Avis-Car-Rentals-In-Greenville-Spartanburg.d6035267-c41.Car-Rental-Guide-Suppliers) - [Car rentals near Greenville Downtown](https://www.expedia.ca/Car-Rentals-In-Greenville-Downtown.d6348006.Car-Rental-Guide) - [Car rentals near Greenville - Spartanburg](https://www.expedia.ca/Car-Rentals-In-Greenville-Spartanburg.d6035267.Car-Rental-Guide) - [Drive on Holidays Rental Cars in Greenville - Spartanburg](https://www.expedia.ca/Drive-On-Holidays-Car-Rentals-In-Greenville-Spartanburg.d6035267-c1050.Car-Rental-Guide-Suppliers) - [Enterprise Rental Cars in Greenville - Spartanburg](https://www.expedia.ca/Enterprise-Car-Rentals-In-Greenville-Spartanburg.d6035267-c15.Car-Rental-Guide-Suppliers) - [National Car Rental Rental Cars in Greenville - Spartanburg](https://www.expedia.ca/National-Car-Rental-Car-Rentals-In-Greenville-Spartanburg.d6035267-c42.Car-Rental-Guide-Suppliers) - [Suv Car Rentals in Greenville - Spartanburg](https://www.expedia.ca/SUV-Car-Rentals-In-Greenville-Spartanburg.d6035267-tSUV.Car-Rental-Guide-Class) - [Things to do in Greenville - Spartanburg](https://www.expedia.ca/Things-To-Do-In-Greenville-Spartanburg.d6035267.Travel-Guide-Activities) - [Book 5 Star Hotels in Greenville on Expedia.com](https://www.expedia.com/5Star-Greenville-Hotels.s50-0-d1388.Travel-Guide-Filter-Hotels)