Title: Book the Best South Carolina Midlands Hotels with Early Check-in in 2025 | Expedia.ca [South Carolina Midlands Travel Guide](https://expedia.ca/South-Carolina-Midlands.dx6057938)[Hotels in South Carolina Midlands](https://expedia.ca/South-Carolina-Midlands-Hotels.d6057938.Travel-Guide-Hotels)[Vacation Rentals in South Carolina Midlands](https://expedia.ca/South-Carolina-Midlands-Vacation-Rentals.d6057938.Travel-Guide-VacationRentals)[Flights to South Carolina Midlands](https://expedia.ca/Cheap-Flights-To-South-Carolina-Midlands.d6057938.Travel-Guide-Flights)[Things to do in South Carolina Midlands](https://expedia.ca/Things-To-Do-In-South-Carolina-Midlands.d6057938.Travel-Guide-Activities)[South Carolina Midlands Car Rentals](https://expedia.ca/Car-Rentals-In-South-Carolina-Midlands.d6057938.Car-Rental-Guide)[South Carolina Midlands Vacation Packages](https://expedia.ca/South-Carolina-Midlands.d6057938.Destination-Travel-Guides) ![South Carolina State House](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/184000/184006-State-House.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels with Early Check-in in South Carolina Midlands, SC - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on South Carolina Midlands Hotels with Early Check-in Tonight [Nov 3 - Nov 4](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-11-03&endDate=2025-11-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 4 - Nov 5](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-11-04&endDate=2025-11-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top South Carolina Midlands Hotels with Early Check-in ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/e78e5670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/67341601.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/170f28f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Santee Santee 9.8/10 Exceptional (1003) "Great stay for a quick weekend getaway!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Danielle CA $170 CA $188 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/c7187353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/25ebdfeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/c5237c95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Santee Santee 8.0/10 Very good (1384) "A nice location, plenty of parking, nice that breakfast was included. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alyssa CA $105 CA $117 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/1bbd70f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Bathtub](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/57735ca3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness studio](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/7b01c436.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/a4197341.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Orangeburg Orangeburg 9.2/10 Wonderful (1017) "It was nice and staff was very nice." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William CA $148 CA $165 total includes taxes & fees Nov 18 - Nov 19 [](https://www.expedia.ca/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/aa173c27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/ae964a26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/f8fbcf77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/c7fdb599.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn by Marriott Orangeburg Orangeburg 8.4/10 Very good (668) "The room was nice and clean. The staff were nice and friendly. The hall to our room was under construction and being remodeled." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dani CA $118 CA $131 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/f8933df9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/45d8f751.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/0f2c01c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/0a695ca8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Columbia/Harbison Columbia 9.0/10 Wonderful (1791) "The hotel was clean and staff was helpful. I will stay again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julena CA $124 CA $138 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Columbia-Hotels-Hilton-Garden-Inn-ColumbiaHarbison.h1513707.Hotel-Information) ![Free continental breakfast](https://images.trvl-media.com/lodging/3000000/2810000/2803700/2803681/ecf8f7be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2810000/2803700/2803681/d098e4c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Corner](https://images.trvl-media.com/lodging/3000000/2810000/2803700/2803681/941cfd6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2810000/2803700/2803681/549be75d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Newberry by IHG Newberry 9.0/10 Wonderful (618) "Excellent breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carmen CA $161 CA $174 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Newberry-Hotels-Holiday-Inn-Express-Suites-Newberry.h2803681.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/54902f8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Two queen beds non smoking](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/e1b5940b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/8a3bfd5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/f127cd7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Manning Manning 8.4/10 Very good (990) "Clean Easy room access, spacious couch and comfortable king bed combination room " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erika CA $167 CA $185 total includes taxes & fees Nov 11 - Nov 12 [](https://www.expedia.ca/Sumter-Hotels-Hampton-Inn-Manning.h1418684.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3200000/3191900/3191843/35e61449.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/4000000/3200000/3191900/3191843/b4cc4b6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3200000/3191900/3191843/d933487d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3200000/3191900/3191843/e3b96f81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Columbia Airport West Columbia 9.0/10 Wonderful (1007) "Great place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melonie CA $154 CA $168 total includes taxes & fees Nov 24 - Nov 25 [](https://www.expedia.ca/Columbia-Hotels-Hilton-Garden-Inn-Columbia-Airport.h3191843.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1360000/1353900/1353807/8d8e8f43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/2000000/1360000/1353900/1353807/ac66b23f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1360000/1353900/1353807/b75d20d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking](https://images.trvl-media.com/lodging/2000000/1360000/1353900/1353807/d1f89564.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Aiken, SC Aiken 8.0/10 Very good (1001) "Great venue" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) john CA $118 CA $133 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Aiken-Hotels-Country-Inn-Suites-By-Radisson.h1353807.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/30000000/29860000/29853300/29853240/3de8df50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/30000000/29860000/29853300/29853240/22dee554.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/30000000/29860000/29853300/29853240/7aa7792a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/30000000/29860000/29853300/29853240/7ffaa80b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Crowne Plaza North Augusta by IHG North Augusta 8.8/10 Excellent (804) "Clean room great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dwayne CA $167 CA $201 total includes taxes & fees Nov 27 - Nov 28 [](https://www.expedia.ca/Aiken-Hotels-Crowne-Plaza-North-Augusta.h29853240.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-17&endDate=2025-11-18®ionId=6057938&adults=2&property_amenities_group_explore=express_checkin&sort=RECOMMENDED&openPlayBack=true) ## Top South Carolina Midlands Hotel Reviews ![Hyatt Place Columbia/Harbison](//images.trvl-media.com/lodging/1000000/330000/327100/327027/68fe8568_y.jpg) ### Hyatt Place Columbia/Harbison 10/10 Excellent "Clean big room! Friendly staff!" 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[Flights from Elgin](https://www.expedia.ca/lp/flights/6051125/flights-from-elgin) - [Allen University](https://www.expedia.ca/Allen-University-Downtown-Columbia.d6245638.Vacation-Attraction) - [Visit Blythewood](https://www.expedia.ca/Blythewood.dx180657) - [Visit Lake Carolina](https://www.expedia.ca/Columbia-Lake-Carolina.dx553248635976478007) - [Visit Forest Acres](https://www.expedia.ca/Forest-Acres.dx553248634998960051) - [Visit Killian](https://www.expedia.ca/Killian.dx553248635975872238) - [Avis Rental Cars in Blythewood](https://www.expedia.ca/Avis-Car-Rentals-In-Blythewood.d180657-c41.Car-Rental-Guide-Suppliers) - [Car rental Elgin](https://www.expedia.ca/Car-Rentals-In-Elgin.d6051125.Car-Rental-Guide) - [Blythewood Vacation Rentals](https://www.expedia.ca/Blythewood-Vacation-Rentals.d180657.Travel-Guide-VacationRentals) - [Book Hotels with Early Check-in in South Carolina Midlands on Expedia.com](https://www.expedia.com/South-Carolina-Midlands-Hotels-Hotel-With-Early-Check-In.0-0-d6057938-thotelwithearlycheckin.Travel-Guide-Filter-Hotels)