South Carolina Midlands Vacation Packages

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Your South Carolina Midlands Vacation

Whether you're heading to South Carolina Midlands for its rich history, spectacular views or something else entirely, this destination is one you won't forget in a hurry. Create your ultimate break with one of our South Carolina Midlands vacation packages. With so much to see and do on a trip to South Carolina Midlands, it can be difficult to know where to start. Kick off your travels in Columbia at Riverbanks Zoo and Garden and Williams Brice Stadium — two popular attractions here. Another city worthy of a spot on your itinerary is Florence. Don't miss Magnolia Mall and Mcleod Regional Medical Centre. Expedia has flights, hotels, car rentals and more to help you create your very own customized South Carolina Midlands vacation today.

Top South Carolina Midlands Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Camelot By the Sea

Camelot By the Sea

3 out of 5
Price was CA $838, price is now CA $567 per person
CA $567
per person
Oct 17 - Oct 21
just found
Roundtrip non-stop flight included
Detroit (DTW) to Myrtle Beach (MYR)
7.4/10 Good! (16 reviews)
Our room was decent - looks like it was newly remodeled to appear better. Other rooms were not as clean. Area around the room could have been better taken care of. Elevator area was dirty. Pool area and beach area were nice, clean, and it’s in a very convenient location near shops and boardwalks!

Reviewed on Jul. 12, 2025

Marina Inn At Grande Dunes

Marina Inn At Grande Dunes

4.5 out of 5
Price was CA $2,396, price is now CA $1,476 per person
CA $1,476
per person
Nov 14 - Nov 21
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Myrtle Beach (MYR)
9.2/10 Wonderful! (1,703 reviews)
A very peaceful place to stay

Reviewed on Aug. 31, 2025

Charlotte Marriott City Center

Charlotte Marriott City Center

4 out of 5
Uptown Charlotte
Price was CA $1,634, price is now CA $1,133 per person
CA $1,133
per person
Nov 20 - Nov 24
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to Charlotte (CLT)
8.8/10 Excellent! (1,002 reviews)
In my room near the bathroom, I noticed peeling paint on the ceiling. It appeared to be from water damage from a leak.

Reviewed on Aug. 24, 2025

The Westin Charlotte

The Westin Charlotte

4 out of 5
Uptown Charlotte
Price was CA $1,476, price is now CA $1,045 per person
CA $1,045
per person
Nov 20 - Nov 24
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to Charlotte (CLT)
9/10 Wonderful! (1,000 reviews)
Nice hotel but the rooms were dated and lacked some modern amenities.

Reviewed on Aug. 21, 2025

Club Wyndham Ocean Boulevard

Club Wyndham Ocean Boulevard

3.5 out of 5
Ocean Drive
Price was CA $1,132, price is now CA $820 per person
CA $820
per person
Oct 10 - Oct 13
found 1 day ago
Roundtrip non-stop flight included
Detroit (DTW) to Myrtle Beach (MYR)
9/10 Wonderful! (803 reviews)
Best Experience I’ve Had Staying At A Hotel!

Reviewed on May 16, 2025

Where to stay in South Carolina Midlands

Find the best South Carolina Midlands areas and neighborhoods for the activities you enjoy most. Learn more about South Carolina Midlands
Columbia

Downtown Columbia

2 out of top 10 points of interest in this area

Travelers come to Downtown Columbia for its lively bars, and you can see top attractions like South Carolina State House and Columbia Museum of Art while you're in town.

Find hotels in Downtown Columbia

Ready to book your vacation to South Carolina Midlands?

 

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South Carolina Midlands Hotel Deals

Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr, Columbia, SC
Fully refundableReserve now, pay when you stay
The price is CA $127 per night from Sep 21 to Sep 22
CA $127
CA $143 total
Sep 21 - Sep 22
includes taxes & fees
Hilton Garden Inn Columbia/Harbison
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
7333 Garners Ferry Rd, Columbia, SC
The price is CA $112 per night from Sep 7 to Sep 8
CA $112
CA $126 total
Sep 7 - Sep 8
includes taxes & fees
La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Wyndham Garden Columbia/Ft. Jackson

Wyndham Garden Columbia/Ft. Jackson

2.5 out of 5
1539 Horseshoe Dr, Columbia, SC
Fully refundableReserve now, pay when you stay
The price is CA $120 per night from Sep 14 to Sep 15
CA $120
CA $134 total
Sep 14 - Sep 15
includes taxes & fees
Wyndham Garden Columbia/Ft. Jackson
See all 2,922 properties in South Carolina Midlands
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Discover the most popular places to visit in South Carolina Midlands

Carowinds Theme Park

Carowinds Theme Park

Choose from 13 roller coasters, chase your friends in a bumper car, enjoy the water slides and beaches of Boomerang Bay, and walk with dinosaurs.

Carowinds Theme Park
Riverbanks Zoo and Garden

Riverbanks Zoo and Garden

Why not meet the animals who call Riverbanks Zoo and Garden home during your trip to Columbia? You can attend a sporting event while in the area.

Riverbanks Zoo and Garden
Congaree National Park

Congaree National Park

While protecting southern hardwood forest for the enjoyment of future generations, this park also offers hiking, canoeing and interesting ranger-led activities.

Congaree National Park
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.