San Francisco Vacation Packages

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Your San Francisco Vacation

When a fun city break is calling, answer it with a vacation package to San Francisco. The neighborhood of El Cangrejo, which is good for distilleries and craft breweries, bars and pubs and cafes, makes a fantastic base for your adventures. You'll want to do a little exploring during your trip to San Francisco. Carve out some time for top attractions such as Miraflores Locks, Bridge of the Americas and Metropolitan Cathedral of Panama. That dream San Francisco vacation is just a few clicks away. Explore flights, accommodations and more on Expedia for an adventure that's tailored to suit your travel style.

Top Holiday Package Deals in San Francisco

Price found within the past 48 hours. Click for updated prices.
Hotel Panamonte

Hotel Panamonte

3.5 out of 5
per person
Jul. 24 - Jul. 28
found 6 hours ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
9.4/10 Exceptional! (67 reviews)
Beautiful gardens and great restaurant with excellent food service. The bedding /sheets were clean and fine, but the bathroom needed more cleaning.

Reviewed on May 13, 2024

La Coralina Island House

La Coralina Island House

3.5 out of 5
per person
Jul. 24 - Jul. 28
found 6 hours ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
9.4/10 Exceptional! (48 reviews)
Great place to relax!

Reviewed on Jun. 19, 2024

NAYARA Bocas del Toro - All Inclusive

NAYARA Bocas del Toro - All Inclusive

4 out of 5
Save 100% on your flight
per person
Jul. 24 - Jul. 28
found 6 hours ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
10/10 Exceptional! (35 reviews)
Amazing property. Peaceful and secluded. Incredible staff.

Reviewed on Feb. 6, 2024

Punta Caracol Acqua Lodge

Punta Caracol Acqua Lodge

3.5 out of 5
Punta Caracol
per person
Jul. 24 - Jul. 28
found 6 hours ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
8.8/10 Excellent! (130 reviews)
Incredible property. The reef was stunning and the staff thoughtful and kind. Everything was clean and comfortable and the food was delicious!

Reviewed on Jun. 5, 2024

Azul Paradise Resort

Azul Paradise Resort

3.5 out of 5
per person
Jul. 24 - Jul. 28
found 6 hours ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
8.4/10 Very Good! (86 reviews)
Azul Paradise exceeded all expectations, thanks to its impeccable accommodations, outstanding service led by managers Jordano and Ricardo, and the unbeatable location. Our bungalow was spacious, immaculately clean, and the panoramic views from the full wall glass windows were simply breathtaking. Waking up to the ocean waves and sounds of the tropical rainforest made us feel totally at peace. While drinking your morning coffee, you will likely see several different species of fish through the glass floor. My wife and I found ourselves with the privacy we needed to reconnect. Often, we were the only ones on the beach, or the only ones on the walking trail enjoying the sounds of nature. We highly recommend this resort, and we look forward to returning in the future!

Reviewed on Apr. 4, 2024

Where to stay in San Francisco

Find the best San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about San Francisco
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Casco Viejo

4/5(32 area reviews)

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Metropolitan Cathedral of Panama or National Theater while you're exploring the area.

Find hotel + flight trips in Casco Viejo

San Francisco Hotel Deals

Decapolis Hotel Panama City
Decapolis Hotel Panama City
4 out of 5
Avenida Balboa Con Multicentro, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is CA $115 per night from Jun. 24 to Jun. 25
CA $115
CA $127 total
includes taxes & fees
Jun 24 - Jun 25
8.2/10 Very Good! (1,003 reviews)
"I love my staying at this hotel because they make me feel welcome every time I am there. Super comfortable bed, excellent breakfast buffet included and the staff is super approachable / accessible to. This is my third staying within one year. thank you guys."

Reviewed on Jun. 15, 2024

Decapolis Hotel Panama City
Megapolis Hotel Panamá
Megapolis Hotel Panamá
4.5 out of 5
Avenida Balboa, Panama City
Fully refundableReserve now, pay when you stay
The price is CA $175 per night from Jun. 24 to Jun. 25
CA $175
CA $192 total
includes taxes & fees
Jun 24 - Jun 25
8.2/10 Very Good! (456 reviews)
"This was far the best ! Location is good . Connect to a shopping mall. Food is great , service was excellent."

Reviewed on Jun. 21, 2024

Megapolis Hotel Panamá
Plaza Paitilla Inn Hotel
Plaza Paitilla Inn Hotel
3.5 out of 5
Italy Avenue, Punta Paitilla, Winston Churchill Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is CA $160 per night from Jun. 24 to Jun. 25
CA $160
CA $176 total
includes taxes & fees
Jun 24 - Jun 25
9/10 Wonderful! (1,427 reviews)
"The view was great and the breakfast was amazing. I will definitely stay in this hotel everytime I visit Panamá."

Reviewed on Jun. 20, 2024

Plaza Paitilla Inn Hotel
See all 1,312 properties in San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Explore other types of vacation packages

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Family Vacations

Family Vacations

Frequently asked questions

How much does a San Francisco vacation package cost?
Much less than you might think — from a low CA $1,052, in fact! By bundling hotels, flights and car rentals into a custom-built vacation package, your San Francisco escape is only clicks away.
How do I get a cheap travel package to San Francisco?
Lock in flights that suit your schedule, add a hotel to your booking and watch how much you save with a San Francisco vacation package. It’s that easy! From flights and hotels to rental cars and activities, Expedia makes traveling on the cheap easy. And with more than 550 partner airlines and 1,000,000 hotel options around the globe to pick from, you’ll never be short of choice.
Where should I stay in San Francisco?
Make sightseeing easy by staying near San Francisco’s main attractions. Miraflores Locks and Metropolitan Cathedral of Panama are two which top many visitors’ bucket lists.
What are the top hotels in San Francisco?
If this will be your first visit to San Francisco, secure a room at Sublime Apartment City Center. Ph Boutique Quartier Atlapa or New Cozy Apartment Ocean View. Quartier Del Mar. Both hotels will make you feel at home and are popular options with lots of travelers.
How far in advance should I book my San Francisco vacation?
It can be hard to know when is the ideal time to book your trip to San Francisco. But typically the earlier you book, the lower the prices. Sometimes, you can reserve your flights and hotels up to a year prior to your departure date. If you’re eager to escape on a last-minute getaway, no need to fret! There are unbeatable deals announced on Expedia every day.
What does an Expedia San Francisco travel package include?
That mostly depends on you. You can choose from a range of San Francisco packages, such as a hotel, rental car and flight. You can also book a hotel and a flight, or a flight and a rental car. Once you’ve made your booking, you can add the fun stuff like experiences and tours. Whatever your ideal San Francisco vacation looks like, you’re sure to save!
What should I know before booking a San Francisco travel package?
So many places to go, so many things to see and do. With a travel package, you’ll be able to afford more of them. Bundle your hotels, flights and rental cars and land big savings.
Can I choose my airline with a San Francisco Expedia vacation package?
Yes, definitely. Expedia has more than 550 airline partners to choose from worldwide. With such a huge range of choice, finding the ideal carrier to whisk you off to San Francisco won’t be difficult.
If I'm not able to travel, can I cancel my San Francisco vacation package?
Your situation can change in a flash, so yes, you can. You may be able to amend or cancel your San Francisco vacation package for free if you’ve booked in the last 24 hours. For older bookings, you can still make changes, but your car rental company, airline or hotel may charge a fee. Need more information? Look up our Customer Service Portal. We’ll help make sure your trip goes off without a hitch.

Discover the most popular places to visit in San Francisco

Image for Multiplaza Pacific Mall

Multiplaza Pacific Mall

4/5(72 reviews)

During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall
Image for ATLAPA Conventions Center

ATLAPA Conventions Center

4/5(1 review)

Learn about the events happening at ATLAPA Conventions Center during your trip to Panama City. Stroll along the seaside in this vibrant area, or check out its top-notch restaurants.

ATLAPA Conventions Center
Image for Multicentro Panama

Multicentro Panama

4/5(26 reviews)

During your trip to Panama City, you can find the perfect gifts to bring home at Multicentro Panama. Stroll along the seaside or visit the casinos in this vibrant area.

Multicentro Panama

Things to do

Image for Live the Experience of a Full Day in San Blas

Live the Experience of a Full Day in San Blas

CA $223
Per adult
100% of travellers recommend
Live the Experience of a Full Day in San Blas
Image for 1- or 2-Night Experience in San Blas Islands

1- or 2-Night Experience in San Blas Islands

CA $352
Per adult
1- or 2-Night Experience in San Blas Islands
Image for Traditional Ecotour Community embera

Traditional Ecotour Community embera

CA $250
Per adult
Traditional Ecotour Community embera
See all activities in Panama City

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.