Title: Book the Best Mesopotamia SPA Resorts  - Spa Hotels in Mesopotamia | Expedia.ca

  

[Mesopotamia Travel Guide](https://expedia.ca/Mesopotamia.dx6208836)[Hotels in Mesopotamia](https://expedia.ca/Mesopotamia-Hotels.d6208836.Travel-Guide-Hotels)[Vacation Rentals in Mesopotamia](https://expedia.ca/Mesopotamia-Vacation-Rentals.d6208836.Travel-Guide-VacationRentals)[Flights to Mesopotamia](https://expedia.ca/Cheap-Flights-To-Mesopotamia.d6208836.Travel-Guide-Flights)[Mesopotamia Car Rentals](https://expedia.ca/Car-Rentals-In-Mesopotamia.d6208836.Car-Rental-Guide)[Mesopotamia Vacation Packages](https://expedia.ca/Mesopotamia.d6208836.Destination-Travel-Guides)

![Mesopotamia which includes forests](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/196000/196542-Mesopotamia.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Find Spa Hotels in Mesopotamia

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## Check availability on Mesopotamia Spa Hotels

Tonight

[Sep 23 - Sep 24](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-09-23&endDate=2025-09-24&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Sep 24 - Sep 25](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-09-24&endDate=2025-09-25&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-09-26&endDate=2025-09-28&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-10-03&endDate=2025-10-05&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Top Mesopotamia Spa Hotels

## Our top choices for Mesopotamia hotels with a spa

![Indoor pool, outdoor pool, open 9:00 AM to 9:00 PM, sun loungers](https://images.trvl-media.com/lodging/11000000/10640000/10633700/10633627/999e0bca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite (Parana)](https://images.trvl-media.com/lodging/11000000/10640000/10633700/10633627/8470c987.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/11000000/10640000/10633700/10633627/c303d064.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/11000000/10640000/10633700/10633627/e7b50f9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Puerto Norte Design Hotel

Rosario

9.2/10

Wonderful

(142)

"Super comfortable and luxurious with amazing view of the river. The staff was courteous enough and parking was easy and right in front of the hotel. "

CA $185

CA $185 total

Sep 26 - Sep 27

[](https://www.expedia.ca/Rosario-Hotels-Puerto-Norte-Design-Hotel.h10633627.Hotel-Information)

![Sauna, steam room, body treatments, hot stone massages, facials](https://images.trvl-media.com/lodging/4000000/3030000/3023900/3023891/891a8cb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/4000000/3030000/3023900/3023891/0fd9db67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Casino](https://images.trvl-media.com/lodging/4000000/3030000/3023900/3023891/6fa88a7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/4000000/3030000/3023900/3023891/4349e1ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pullman Rosario City Center Hotel

Rosario

8.6/10

Excellent

(272)

"Nice"

CA $161

CA $161 total

Sep 24 - Sep 25

[](https://www.expedia.ca/Rosario-Hotels-Pullman-Rosario-City-Center-Hotel.h3023891.Hotel-Information)

![Massages](https://images.trvl-media.com/lodging/97000000/96450000/96446000/96445971/bd533bb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/97000000/96450000/96446000/96445971/433c57ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/97000000/96450000/96446000/96445971/1950856d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/97000000/96450000/96446000/96445971/c44de299.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Howard Johnson Plaza La Ribera

Resistencia

9.2/10

Wonderful

(104)

"An outstanding hotel, new, in a very good environment, quite close to the city. Modern rooms, good technology, plus a very generous breakfast."

CA $93

CA $93 total

Sep 24 - Sep 25

[](https://www.expedia.ca/Resistencia-Hotels-Howard-Johnson-Plaza-La-Ribera.h96445971.Hotel-Information)

![Indoor pool, 2 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/182c3232.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/8d2994c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Double Room](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/e22e8bc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/384ea822.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Mayim Hotel Termal & SPA

Concordia

9.0/10

Wonderful

(4)

"Muito bom o hotel. Atendimento excelente e comida também "

CA $116

CA $116 total

Oct 22 - Oct 23

[](https://www.expedia.ca/Concordia-Hotels-Mayim-Hotel-Termal-SPA.h111541690.Hotel-Information)

![Couples treatment rooms, body treatments, aromatherapy, body scrubs](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/96c06c0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/6a6d02f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Double Room](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/4e070a0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/77b70130.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Maran Suites & Towers - Hotel & Spa

Parana

9.0/10

Wonderful

(30)

"Great location and friendly, accommodating staff. "

CA $116

CA $116 total

Oct 1 - Oct 2

[](https://www.expedia.ca/Parana-Hotels-Maran-Suites-Towers-Hotel-Spa.h36800965.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/ee9ad702.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/e70d9e85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/dd41bc20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free self parking](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/00b851ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel y Spa Termas del Este

Federacion

8.4/10

Very good

(12)

"good for a 1 night stay"

CA $73

CA $73 total

Sep 24 - Sep 25

[](https://www.expedia.ca/Federacion-Hotels-Hotel-Y-Spa-Termas-Del-Este.h33346911.Hotel-Information)

![2 bedrooms, premium bedding, pillowtop beds, individually decorated](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/9cad496d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business Apartment | Private kitchen](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/3ee5dbf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/5f45ac2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business Apartment | Living area](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/1f4c0785.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Agustín 1 Apart

Parana

9.0/10

Wonderful

(4)

CA $87

CA $87 total

Sep 24 - Sep 25

[](https://www.expedia.ca/Parana-Hotels-Agustin-1-Apart.h99269311.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/afd7d710.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/f32e7494.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/7876fff6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/750a674d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Club Valle Termal Resort

Federacion

9.2/10

Wonderful

(93)

CA $57

CA $57 total

Sep 28 - Sep 29

[](https://www.expedia.ca/Federacion-Hotels-Club-Valle-Termal-Resort.h11875903.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/43c3ae01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, free WiFi, bed sheets](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/96c73453.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/c45620e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Sauna, steam room, body treatments, hot stone massages, facials](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/ef76fc3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Costarenas Hotel & Spa

Colon

8.6/10

Excellent

(57)

CA $156

CA $156 total

Sep 24 - Sep 25

[](https://www.expedia.ca/Colon-Hotels-Costarenas-Hotel-Spa.h15362145.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/cb01ff56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/a2d4eb00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/c1286a77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/0f7006fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Intersur Colon

Colón

10/10

Exceptional

(2)

"Letti molto comodi, belle piscine, personale gentile, pulizia buona, colazione buona. Ottimo rapporto qualità prezzo. "

CA $130

CA $130 total

Oct 24 - Oct 25

[](https://www.expedia.ca/Colon-Hotels-Intersur-Colon.h114109755.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-07&endDate=2025-10-08&regionId=6208836&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true)

## Top Mesopotamia Hotel Reviews

![Costarenas Hotel & Spa](//images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/43c3ae01_y.jpg)

### Costarenas Hotel & Spa

2/10 Terrible

"Short Version See pictures for detailed information) - Rooms and bathrooms are small, shower already tight spaced with doors that don’t close properly. - By day 3, construction noise and chemicals smells from remodeling work became a big issue. - Receptionist did not offer solutions and lied about remodeling hours. Felt uncomfortable when asked for manager’s name, and refused to give any other information. - Same receptionist reached out later to apologize and acknowledged we should have not been placed in those rooms to begin with. Offered to move us to “upgraded” rooms. - “Upgraded” rooms were even worse. One of the rooms was directly under the ones being remodeled and worked on. Noise began at 8 AM - The other two rooms did not have a functioning air conditioner. Staff gave poor excuse and just said to open windows. There’s tons of noise far into the night from motor bikes and people playing music right across the hotel. - Hotel breakfast was motel level at best. You get eggs swimming in water and some cut up ham. Toasters barely worked, and when staff was asked for replacement they appeared completely clueless. - The spa experience was good when it came to the massage. However “quiet” policy is not enforced and hearing toilets go off right next to the spa area don’t help with the experience. - Check out was the final straw. Desk staff was rude and dismissive of concerns, stating that the room “upgrade” was sufficient compensation for the troubles. "

[](https://expedia.ca/Colon-Hotels-Costarenas-Hotel-Spa.h15362145.Hotel-Information)

![Holiday Inn Rosario by IHG](//images.trvl-media.com/lodging/1000000/580000/570400/570357/61653463_y.jpg)

### Holiday Inn Rosario by IHG

10/10 Excellent

"Todo perfecto "

[](https://expedia.ca/Rosario-Hotels-Holiday-Inn-Rosario.h570357.Hotel-Information)

![Holiday Inn Express Rosario by IHG](//images.trvl-media.com/lodging/4000000/3250000/3243000/3242923/502819d5_y.jpg)

### Holiday Inn Express Rosario by IHG

10/10 Excellent

"Very clean and spacious. Hearty breakfast. Very courteous staff"

[](https://expedia.ca/Rosario-Hotels-Holiday-Inn-Express-Rosario.h3242923.Hotel-Information)

![Esplendor by Wyndham Savoy Rosario](//images.trvl-media.com/lodging/3000000/2810000/2803500/2803473/36b8ac51_y.jpg)

### Esplendor by Wyndham Savoy Rosario

10/10 Excellent

"Excellent hotel Everything very comfortable, and convenient"

[](https://expedia.ca/Rosario-Hotels-Esplendor-By-Wyndham-Savoy-Rosario.h2803473.Hotel-Information)

![Howard Johnson by Wyndham Rosario](//images.trvl-media.com/lodging/14000000/13520000/13514300/13514290/3d666cad_y.jpg)

### Howard Johnson by Wyndham Rosario

10/10 Excellent

"Super conveniente por precio y calidad."

[](https://expedia.ca/Rosario-Hotels-Howard-Johnson-Rosario.h13514290.Hotel-Information)

![Hathor Concordia](//images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/cc821f0d_y.jpg)

### Hathor Concordia

10/10 Excellent

"Very clean room at affordable price. The dinning is of excellent quality at very reasonable price. The staff are quite friendly and helpful."

[](https://expedia.ca/Concordia-Hotels-Hathor-Concordia.h4668235.Hotel-Information)

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