Title: Book the Best Mesopotamia SPA Resorts from CA $74 - Spa Hotels in Mesopotamia | Expedia.ca

[Mesopotamia Travel Guide](https://expedia.ca/Mesopotamia.dx6208836)[Hotels in Mesopotamia](https://expedia.ca/Mesopotamia-Hotels.d6208836.Travel-Guide-Hotels)[Vacation Rentals in Mesopotamia](https://expedia.ca/Mesopotamia-Vacation-Rentals.d6208836.Travel-Guide-VacationRentals)[Flights to Mesopotamia](https://expedia.ca/Cheap-Flights-To-Mesopotamia.d6208836.Travel-Guide-Flights)[Mesopotamia Car Rentals](https://expedia.ca/Car-Rentals-In-Mesopotamia.d6208836.Car-Rental-Guide)[Mesopotamia Vacation Packages](https://expedia.ca/Mesopotamia.d6208836.Destination-Travel-Guides)

![Mesopotamia showing a river or creek and forests](https://images.trvl-media.com/place/6208836/ca0c6990-9932-4f38-bee6-e89ce7080803.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Find Spa Hotels in Mesopotamia from CA $74

- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg)  
###  
Change your mind  
Book hotels with free cancellation
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg)  
###  
Treat yourself  
Sign in to save 10% or more on thousands of hotels  
[Sign in](https://www.expedia.ca/login)
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg)  
###  
Be picky  
Search almost a million properties worldwide

## Check availability on Mesopotamia Spa Hotels

Tonight

[Dec 31 - Jan 1](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-12-31&endDate=2026-01-01&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Jan 1 - Jan 2](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2026-01-01&endDate=2026-01-02&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2026-01-02&endDate=2026-01-04&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2026-01-09&endDate=2026-01-11&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Mesopotamia hotels with a spa

![Sauna, steam room](https://images.trvl-media.com/lodging/121000000/120520000/120517600/120517502/1c9ec1fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Double Room, 2 Queen Beds, City View](https://images.trvl-media.com/lodging/121000000/120520000/120517600/120517502/ba612e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/121000000/120520000/120517600/120517502/dd975896.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/121000000/120520000/120517600/120517502/w1021h683x3y0-b40ed89a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Turismo Hotel Casino

[](https://www.expedia.ca/Corrientes-Hotels-Turismo-Hotel-Casino.h120517502.Hotel-Information)

Corrientes

CA $180

CA $180 total

Jan 25 - Jan 26, 2026

[](https://www.expedia.ca/Corrientes-Hotels-Turismo-Hotel-Casino.h120517502.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/43c3ae01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/c45620e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/a0cc5957.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Sauna, steam room, body treatments, hot stone massages, facials](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/ef76fc3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Costarenas Hotel & Spa

[](https://www.expedia.ca/Colon-Hotels-Costarenas-Hotel-Spa.h15362145.Hotel-Information)

Colon

8.6/10

Excellent

(58)

"spectacular since we arrived the tstaff was wonderful and kind to us very helpful and nice answering all our questions, the hotel very comfortable!! the river view stunning"

![Argentina](https://a.travel-assets.com/egds/marks/flags/ar.svg)

Lisette

[](https://www.expedia.ca/Colon-Hotels-Costarenas-Hotel-Spa.h15362145.Hotel-Information)

![Indoor pool, 2 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/182c3232.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/8d2994c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/384ea822.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/a0871cfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Mayim Hotel Termal & SPA

[](https://www.expedia.ca/Concordia-Hotels-Mayim-Hotel-Termal-SPA.h111541690.Hotel-Information)

Concordia

8.8/10

Excellent

(5)

"Muy lindo hotel , lástima q se rompió el aire acondicionado y no hay secador de pelo an la habitación "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Catalina

CA $132

CA $132 total

Jan 8 - Jan 9, 2026

[](https://www.expedia.ca/Concordia-Hotels-Mayim-Hotel-Termal-SPA.h111541690.Hotel-Information)

![Couples treatment rooms, body treatments, aromatherapy, body scrubs](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/96c06c0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Double Room](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/4e070a0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment rooms, body treatments, aromatherapy, body scrubs](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/2f9d647c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/77b70130.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Maran Suites & Towers - Hotel & Spa

[](https://www.expedia.ca/Parana-Hotels-Maran-Suites-Towers-Hotel-Spa.h36800965.Hotel-Information)

Parana

9.2/10

Wonderful

(31)

"Great location and friendly, accommodating staff. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Michael

CA $115

CA $115 total

Jan 5 - Jan 6, 2026

[](https://www.expedia.ca/Parana-Hotels-Maran-Suites-Towers-Hotel-Spa.h36800965.Hotel-Information)

![Premium bedding, pillowtop beds, individually decorated](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/9cad496d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Duplex | Living area](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/1eee7dc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business Apartment | Living area](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/1f4c0785.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business Apartment | Private kitchen](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/3ee5dbf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Agustín 1 Apart

[](https://www.expedia.ca/Parana-Hotels-Agustin-1-Apart.h99269311.Hotel-Information)

Parana

9.0/10

Wonderful

(4)

"Meu problema foi só a garagem, o apartamento é ótimo, limpeza estava impecável."

![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg)

Jose rodrigo kallas

CA $74

CA $74 total

Jan 4 - Jan 5, 2026

[](https://www.expedia.ca/Parana-Hotels-Agustin-1-Apart.h99269311.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/16000000/15470000/15462600/15462513/09f8552d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/16000000/15470000/15462600/15462513/e8b23b5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/16000000/15470000/15462600/15462513/e9f90dd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/16000000/15470000/15462600/15462513/29357765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Rio Arriba Suites Apartments y Resto

[](https://www.expedia.ca/Bella-Vista-Hotels-Rio-Arriba-Suites-Apartments-Y-Resto.h15462513.Hotel-Information)

Bella Vista

8.6/10

Excellent

(4)

"Pessoal da recepção excelente acolhimento. Hotel bonito, falta manutenção em certos lugares. Quarto ótimo, cama com colchão selado e barulho nos ares condicionados. Café da manhã deixa a desejar. Restaurante muito bonito. "

![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg)

Anonymous traveller

[](https://www.expedia.ca/Bella-Vista-Hotels-Rio-Arriba-Suites-Apartments-Y-Resto.h15462513.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/ee9ad702.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/e70d9e85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/459986e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free self parking](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/00b851ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel y Spa Termas del Este

[](https://www.expedia.ca/Federacion-Hotels-Hotel-Y-Spa-Termas-Del-Este.h33346911.Hotel-Information)

Federacion

8.4/10

Very good

(12)

"good for a 1 night stay"

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Chase

[](https://www.expedia.ca/Federacion-Hotels-Hotel-Y-Spa-Termas-Del-Este.h33346911.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/cb01ff56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/a2d4eb00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/c1286a77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/cdd97d7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Intersur Colon

[](https://www.expedia.ca/Colon-Hotels-Intersur-Colon.h114109755.Hotel-Information)

Colón

10/10

Exceptional

(3)

"Letti molto comodi, belle piscine, personale gentile, pulizia buona, colazione buona. Ottimo rapporto qualità prezzo. "

![Italy](https://a.travel-assets.com/egds/marks/flags/it.svg)

Francesco

CA $122

CA $122 total

Jan 19 - Jan 20, 2026

[](https://www.expedia.ca/Colon-Hotels-Intersur-Colon.h114109755.Hotel-Information)

![Sauna, steam room, body treatments, hot stone massages, facials](https://images.trvl-media.com/lodging/4000000/3030000/3023900/3023891/891a8cb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/4000000/3030000/3023900/3023891/0fd9db67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Aerial view](https://images.trvl-media.com/lodging/4000000/3030000/3023900/3023891/3b6899cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Casino](https://images.trvl-media.com/lodging/4000000/3030000/3023900/3023891/6fa88a7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pullman Rosario City Center Hotel

[](https://www.expedia.ca/Rosario-Hotels-Pullman-Rosario-City-Center-Hotel.h3023891.Hotel-Information)

Rosario

8.6/10

Excellent

(273)

"Nice"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

juan

[](https://www.expedia.ca/Rosario-Hotels-Pullman-Rosario-City-Center-Hotel.h3023891.Hotel-Information)

![Indoor pool, outdoor pool, open 9:00 AM to 9:00 PM, sun loungers](https://images.trvl-media.com/lodging/11000000/10640000/10633700/10633627/999e0bca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/11000000/10640000/10633700/10633627/64dd1add.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/11000000/10640000/10633700/10633627/e7b50f9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/11000000/10640000/10633700/10633627/c303d064.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Puerto Norte Design Hotel

[](https://www.expedia.ca/Rosario-Hotels-Puerto-Norte-Design-Hotel.h10633627.Hotel-Information)

Rosario

9.2/10

Wonderful

(143)

"Super comfortable and luxurious with amazing view of the river. The staff was courteous enough and parking was easy and right in front of the hotel. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Katie

[](https://www.expedia.ca/Rosario-Hotels-Puerto-Norte-Design-Hotel.h10633627.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-14&endDate=2026-01-15&regionId=6208836&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true)

## Top Mesopotamia Hotel Reviews

![Holiday Inn Rosario by IHG](https://images.trvl-media.com/lodging/1000000/580000/570400/570357/61653463_y.jpg)

### Holiday Inn Rosario by IHG

10/10 Excellent

"Thank you !!!!"

[](https://expedia.ca/Rosario-Hotels-Holiday-Inn-Rosario.h570357.Hotel-Information)

![Hathor Concordia](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/cc821f0d_y.jpg)

### Hathor Concordia

10/10 Excellent

"The hotel staff is very polite Service: "Friendly and efficient," "helpful," "attentive," "welcoming smile," "professional"."

[](https://expedia.ca/Concordia-Hotels-Hathor-Concordia.h4668235.Hotel-Information)

![Holiday Inn Express Rosario by IHG](https://images.trvl-media.com/lodging/4000000/3250000/3243000/3242923/502819d5_y.jpg)

### Holiday Inn Express Rosario by IHG

10/10 Excellent

"It's a perfect please to stay! "

[](https://expedia.ca/Rosario-Hotels-Holiday-Inn-Express-Rosario.h3242923.Hotel-Information)

![Amérian Hotel Casino Gala](https://images.trvl-media.com/lodging/2000000/1200000/1197100/1197026/a75881f1_y.jpg)

### Amérian Hotel Casino Gala

10/10 Excellent

"Good check in"

[](https://expedia.ca/Resistencia-Hotels-Amerian-Hotel-Casino-Gala.h1197026.Hotel-Information)

![Club Valle Termal Resort](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/afd7d710_y.jpg)

### Club Valle Termal Resort

10/10 Excellent

"La habitación estaba impecable, la limpieza de todo el complejo fue excelente, pero quiero destacar la atención de todo su personal, la disponibilidad constante para atender todas nuestras necesidades. Lo recomiendo y espero poder volver pronto."

[](https://expedia.ca/Federacion-Hotels-Club-Valle-Termal-Resort.h11875903.Hotel-Information)

![Costarenas Hotel & Spa](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/43c3ae01_y.jpg)

### Costarenas Hotel & Spa

2/10 Terrible

"Short Version See pictures for detailed information) - Rooms and bathrooms are small, shower already tight spaced with doors that don’t close properly. - By day 3, construction noise and chemicals smells from remodeling work became a big issue. - Receptionist did not offer solutions and lied about remodeling hours. Felt uncomfortable when asked for manager’s name, and refused to give any other information. - Same receptionist reached out later to apologize and acknowledged we should have not been placed in those rooms to begin with. Offered to move us to “upgraded” rooms. - “Upgraded” rooms were even worse. One of the rooms was directly under the ones being remodeled and worked on. Noise began at 8 AM - The other two rooms did not have a functioning air conditioner. Staff gave poor excuse and just said to open windows. There’s tons of noise far into the night from motor bikes and people playing music right across the hotel. - Hotel breakfast was motel level at best. You get eggs swimming in water and some cut up ham. Toasters barely worked, and when staff was asked for replacement they appeared completely clueless. - The spa experience was good when it came to the massage. However “quiet” policy is not enforced and hearing toilets go off right next to the spa area don’t help with the experience. - Check out was the final straw. Desk staff was rude and dismissive of concerns, stating that the room “upgrade” was sufficient compensation for the troubles. "

[](https://expedia.ca/Colon-Hotels-Costarenas-Hotel-Spa.h15362145.Hotel-Information)

![Wyndham Garden Campana](https://images.trvl-media.com/lodging/1000000/990000/983700/983698/1521535a_y.jpg)

### Wyndham Garden Campana

6/10 Okay

"Televisor con problemas de funcionamiento. Ducha que baña todo el baño en lugar de ti. Ventana expuesta al paso de todo el público. "

[](https://expedia.ca/Pilar-Hotels-Australis-Campana.h983698.Hotel-Information)

## Explore a world of travel with Expedia

- More ways to book

- [Book Spa Hotels in Mesopotamia on Expedia.com.ar ](https://www.expedia.com.ar/Mesopotamia-Hoteles-Hotel-Con-Spa.0-0-d6208836-tHotelconspa.Guia-filtrada-de-Hoteles)