Title: Book the Best Mesopotamia SPA Resorts  - Spa Hotels in Mesopotamia | Expedia.ca

 

[Mesopotamia Travel Guide](https://expedia.ca/Mesopotamia.dx6208836)[Hotels in Mesopotamia](https://expedia.ca/Mesopotamia-Hotels.d6208836.Travel-Guide-Hotels)[Vacation Rentals in Mesopotamia](https://expedia.ca/Mesopotamia-Vacation-Rentals.d6208836.Travel-Guide-VacationRentals)[Flights to Mesopotamia](https://expedia.ca/Cheap-Flights-To-Mesopotamia.d6208836.Travel-Guide-Flights)[Mesopotamia Car Rentals](https://expedia.ca/Car-Rentals-In-Mesopotamia.d6208836.Car-Rental-Guide)[Mesopotamia Vacation Packages](https://expedia.ca/Mesopotamia.d6208836.Destination-Travel-Guides)

![Mesopotamia showing a river or creek and forests](https://images.trvl-media.com/place/6208836/ca0c6990-9932-4f38-bee6-e89ce7080803.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Find Spa Hotels in Mesopotamia

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## Check availability on Mesopotamia Spa Hotels

Tonight

[Nov 9 - Nov 10](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-11-09&endDate=2025-11-10&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Nov 10 - Nov 11](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-11-10&endDate=2025-11-11&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-11-14&endDate=2025-11-16&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two weeks

[Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-11-21&endDate=2025-11-23&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Top Mesopotamia Spa Hotels

![Exterior](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/afd7d710.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/750a674d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/f32e7494.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/60e3bf31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Club Valle Termal Resort

Federacion

9.2/10

Wonderful

(93)

"Lamentablemente el lugar no refleja lo contratado por la plataforma. Cuando llegamos no tenían nuestras reservas, nos enviaron a una habitación con puerta de vidrio que no cerraba, arañas en la habitación, las sábanas viejas y manchadas, colchones vencidos y sin forro. Una experiencia espeluznante. "

![Costa Rica](https://a.travel-assets.com/egds/marks/flags/cr.svg)

Pablo

CA $67

CA $67 total

Dec 1 - Dec 2

[](https://www.expedia.ca/Federacion-Hotels-Club-Valle-Termal-Resort.h11875903.Hotel-Information)

![Couples treatment rooms, body treatments, aromatherapy, body scrubs](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/96c06c0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/6a6d02f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment rooms, body treatments, aromatherapy, body scrubs](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/2f9d647c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/77b70130.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Maran Suites & Towers - Hotel & Spa

Parana

9.0/10

Wonderful

(30)

"Property is fine. The woman who checked me in was extremely rude. Rooms don’t have accessible access to outlets."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brian

CA $133

CA $133 total

Dec 1 - Dec 2

[](https://www.expedia.ca/Parana-Hotels-Maran-Suites-Towers-Hotel-Spa.h36800965.Hotel-Information)

![Indoor pool, 2 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/182c3232.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/8d2994c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/384ea822.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Double Room](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/e22e8bc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Mayim Hotel Termal & SPA

Concordia

8.8/10

Excellent

(5)

"Muy lindo hotel , lástima q se rompió el aire acondicionado y no hay secador de pelo an la habitación "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Catalina

CA $132

CA $132 total

Nov 19 - Nov 20

[](https://www.expedia.ca/Concordia-Hotels-Mayim-Hotel-Termal-SPA.h111541690.Hotel-Information)

![2 bedrooms, premium bedding, pillowtop beds, individually decorated](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/9cad496d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business Apartment | Private kitchen](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/3ee5dbf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/5f45ac2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business Apartment | Living area](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/1f4c0785.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Agustín 1 Apart

Parana

9.0/10

Wonderful

(4)

"Meu problema foi só a garagem, o apartamento é ótimo, limpeza estava impecável."

![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg)

Jose rodrigo kallas

CA $126

CA $126 total

Nov 11 - Nov 12

[](https://www.expedia.ca/Parana-Hotels-Agustin-1-Apart.h99269311.Hotel-Information)

![Seasonal outdoor pool, open noon to 11:00 PM, sun loungers](https://images.trvl-media.com/lodging/5000000/4420000/4411700/4411601/456e237c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/5000000/4420000/4411700/4411601/98196436.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/5000000/4420000/4411700/4411601/d89014ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily buffet breakfast (USD 3 per person)](https://images.trvl-media.com/lodging/5000000/4420000/4411700/4411601/01834db8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Casona de Susana

Colon

7.4/10

Good

(25)

"La propietaria respeta el precio acordado. En verano si usás más de 8 horas por día el aire acondicionado te cobran un plus."

![Argentina](https://a.travel-assets.com/egds/marks/flags/ar.svg)

Marlene Ruth

CA $67

CA $67 total

Dec 3 - Dec 4

[](https://www.expedia.ca/Colon-Hotels-La-Casona-De-Susana.h4411601.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/ee9ad702.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/459986e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free self parking](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/00b851ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/e70d9e85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel y Spa Termas del Este

Federacion

8.4/10

Very good

(12)

"good for a 1 night stay"

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Chase

[](https://www.expedia.ca/Federacion-Hotels-Hotel-Y-Spa-Termas-Del-Este.h33346911.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/cb01ff56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/cdd97d7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/0f7006fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/a2d4eb00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Intersur Colon

Colón

10/10

Exceptional

(2)

"Letti molto comodi, belle piscine, personale gentile, pulizia buona, colazione buona. Ottimo rapporto qualità prezzo. "

![Italy](https://a.travel-assets.com/egds/marks/flags/it.svg)

Francesco

CA $125

CA $125 total

Nov 11 - Nov 12

[](https://www.expedia.ca/Colon-Hotels-Intersur-Colon.h114109755.Hotel-Information)

![Massages](https://images.trvl-media.com/lodging/97000000/96450000/96446000/96445971/bd533bb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/97000000/96450000/96446000/96445971/c44de299.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/97000000/96450000/96446000/96445971/433c57ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/97000000/96450000/96446000/96445971/d08855c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Howard Johnson Plaza La Ribera

Resistencia

9.2/10

Wonderful

(112)

"Excellent hotel! Staff was friendly and professional. Big rooms, super clean. We are a family of 5 (2 adults and 3 kids) and we stayed for 2 nights. We had a great experience! The pool is fantastic, there is a big green outdoor area with playground for kids. We really enjoyed our time there! There is a big shopping centre in front of the hotel. "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Ovidio Enrique

[](https://www.expedia.ca/Resistencia-Hotels-Howard-Johnson-Plaza-La-Ribera.h96445971.Hotel-Information)

![Sauna, steam room, body treatments, hot stone massages, facials](https://images.trvl-media.com/lodging/4000000/3030000/3023900/3023891/891a8cb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Casino](https://images.trvl-media.com/lodging/4000000/3030000/3023900/3023891/6fa88a7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/4000000/3030000/3023900/3023891/4349e1ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Aerial view](https://images.trvl-media.com/lodging/4000000/3030000/3023900/3023891/3b6899cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pullman Rosario City Center Hotel

Rosario

8.6/10

Excellent

(272)

"Safe and good hotel. Fitness center needs to be improved"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Olivier

[](https://www.expedia.ca/Rosario-Hotels-Pullman-Rosario-City-Center-Hotel.h3023891.Hotel-Information)

![Indoor pool, outdoor pool, open 9:00 AM to 9:00 PM, sun loungers](https://images.trvl-media.com/lodging/11000000/10640000/10633700/10633627/999e0bca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/11000000/10640000/10633700/10633627/c303d064.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite (Parana)](https://images.trvl-media.com/lodging/11000000/10640000/10633700/10633627/8470c987.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/11000000/10640000/10633700/10633627/e7b50f9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Puerto Norte Design Hotel

Rosario

9.2/10

Wonderful

(142)

"When booking a Suite (Paraná) I expected two things: a suite and a view of the river. I got neither. The "suite" is nothing more than a large hotel room and not worth the extra cost. There was no view of the river from the room. The room is modern however on arrival the air conditioning was set extremely high and changing the control didn't seem to make any difference. The breakfast room did not seem capable of handling the number of guests and was very cramped, although the breakfast itself...

![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg)

Benjamin

[](https://www.expedia.ca/Rosario-Hotels-Puerto-Norte-Design-Hotel.h10633627.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-24&endDate=2025-11-25&regionId=6208836&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true)

## Top Mesopotamia Hotel Reviews

![InterTower Hotel](//images.trvl-media.com/lodging/10000000/9850000/9845300/9845278/13fc6ccf_y.jpg)

### InterTower Hotel

10/10 Excellent

"Everything was perfect!!"

[](https://expedia.ca/Santa-Fe-Hotels-InterTower-Hotel.h9845278.Hotel-Information)

![Holiday Inn Express Rosario by IHG](//images.trvl-media.com/lodging/4000000/3250000/3243000/3242923/502819d5_y.jpg)

### Holiday Inn Express Rosario by IHG

10/10 Excellent

"Clean room. Everything just like in the pictures. "

[](https://expedia.ca/Rosario-Hotels-Holiday-Inn-Express-Rosario.h3242923.Hotel-Information)

![Costarenas Hotel & Spa](//images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/43c3ae01_y.jpg)

### Costarenas Hotel & Spa

2/10 Terrible

"Short Version See pictures for detailed information) - Rooms and bathrooms are small, shower already tight spaced with doors that don’t close properly. - By day 3, construction noise and chemicals smells from remodeling work became a big issue. - Receptionist did not offer solutions and lied about remodeling hours. Felt uncomfortable when asked for manager’s name, and refused to give any other information. - Same receptionist reached out later to apologize and acknowledged we should have not been placed in those rooms to begin with. Offered to move us to “upgraded” rooms. - “Upgraded” rooms were even worse. One of the rooms was directly under the ones being remodeled and worked on. Noise began at 8 AM - The other two rooms did not have a functioning air conditioner. Staff gave poor excuse and just said to open windows. There’s tons of noise far into the night from motor bikes and people playing music right across the hotel. - Hotel breakfast was motel level at best. You get eggs swimming in water and some cut up ham. Toasters barely worked, and when staff was asked for replacement they appeared completely clueless. - The spa experience was good when it came to the massage. However “quiet” policy is not enforced and hearing toilets go off right next to the spa area don’t help with the experience. - Check out was the final straw. Desk staff was rude and dismissive of concerns, stating that the room “upgrade” was sufficient compensation for the troubles. "

[](https://expedia.ca/Colon-Hotels-Costarenas-Hotel-Spa.h15362145.Hotel-Information)

![Amérian Hotel Casino Gala](//images.trvl-media.com/lodging/2000000/1200000/1197100/1197026/a75881f1_y.jpg)

### Amérian Hotel Casino Gala

10/10 Excellent

"Great service and attention!. I highly recommend this hotel . "

[](https://expedia.ca/Resistencia-Hotels-Amerian-Hotel-Casino-Gala.h1197026.Hotel-Information)

![Holiday Inn Rosario by IHG](//images.trvl-media.com/lodging/1000000/580000/570400/570357/61653463_y.jpg)

### Holiday Inn Rosario by IHG

10/10 Excellent

"Todo perfecto "

[](https://expedia.ca/Rosario-Hotels-Holiday-Inn-Rosario.h570357.Hotel-Information)

![Esplendor by Wyndham Savoy Rosario](//images.trvl-media.com/lodging/3000000/2810000/2803500/2803473/36b8ac51_y.jpg)

### Esplendor by Wyndham Savoy Rosario

10/10 Excellent

"Excellent hotel Everything very comfortable, and convenient"

[](https://expedia.ca/Rosario-Hotels-Esplendor-By-Wyndham-Savoy-Rosario.h2803473.Hotel-Information)

![Howard Johnson by Wyndham Rosario](//images.trvl-media.com/lodging/14000000/13520000/13514300/13514290/3d666cad_y.jpg)

### Howard Johnson by Wyndham Rosario

10/10 Excellent

"Super conveniente por precio y calidad."

[](https://expedia.ca/Rosario-Hotels-Howard-Johnson-Rosario.h13514290.Hotel-Information)

![Wyndham Garden Campana](//images.trvl-media.com/lodging/1000000/990000/983700/983698/1521535a_y.jpg)

### Wyndham Garden Campana

6/10 Okay

"Televisor con problemas de funcionamiento. Ducha que baña todo el baño en lugar de ti. Ventana expuesta al paso de todo el público. "

[](https://expedia.ca/Pilar-Hotels-Australis-Campana.h983698.Hotel-Information)

![Hathor Concordia](//images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/cc821f0d_y.jpg)

### Hathor Concordia

10/10 Excellent

"Very clean room at affordable price. The dinning is of excellent quality at very reasonable price. The staff are quite friendly and helpful."

[](https://expedia.ca/Concordia-Hotels-Hathor-Concordia.h4668235.Hotel-Information)

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