Title: Lyon Vacation Home Rentals from CA $287: Search Top Private Vacation Homes for Rent | Expedia.ca [Hotels in Lyon](https://expedia.ca/Lyon-Hotels.d553248634998705303.Travel-Guide-Hotels)[Vacation Rentals in Lyon](https://expedia.ca/Lyon-Vacation-Rentals.d553248634998705303.Travel-Guide-VacationRentals)[Lyon Car Rentals](https://expedia.ca/Car-Rentals-In-Lyon.d553248634998705303.Car-Rental-Guide)[Lyon Vacation Packages](https://expedia.ca/Lyon.d553248634998705303.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Lyon Vacation Rentals ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248634998705303&startDate=2025-11-07&endDate=2025-11-09&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=553248634998705303&startDate=2025-11-14&endDate=2025-11-16&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=553248634998705303&startDate=2025-11-28&endDate=2025-11-30&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248634998705303&startDate=2025-12-26&endDate=2025-12-28&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select Lyon Vacation Homes ![Property grounds](https://images.trvl-media.com/lodging/88000000/87720000/87715200/87715200/w506h683x258y0-f5f92a51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/88000000/87720000/87715200/87715200/104def98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/88000000/87720000/87715200/87715200/w918h683x47y0-d04d85e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, DVD player, books](https://images.trvl-media.com/lodging/88000000/87720000/87715200/87715200/w904h683x60y0-e75a6da7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Sunflower Penthouse on the River in Clarksdale Clarksdale 9.2/10 Wonderful (20) "Beautiful setting very close to the town of blues! Beds were very comfortable & outdoor seating was lovely ! I would recommend staying there for a comfortable & convenient visit to Clarksdsle!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary B. CA $182 CA $304 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Clarksdale-Hotels-The-Sunflower-Penthouse-On-The-River-In-Clarksdale.h87715200.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/114000000/113150000/113140300/113140229/029d0d24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/114000000/113150000/113140300/113140229/d17187c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/114000000/113150000/113140300/113140229/97d833e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/114000000/113150000/113140300/113140229/33354a52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 1-bedroom house in fabulous Clarksdale with WiFi Clarksdale CA $210 CA $287 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Clarksdale-Hotels-Charming-1-Bedroom-House-In-Fabulous-Clarksdale-With-WiFi.h113140229.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-11&endDate=2025-11-12®ionId=553248634998705303&adults=2&lodging=VACATION_HOME&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLyon-Private-Vacation-Homes.d553248634998705303-aaPrivateVacationHomes.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLyon-Private-Vacation-Homes.d553248634998705303-aaPrivateVacationHomes.Travel-Guide-Accommodation) ## Top Lyon Hotel Reviews ![Casa D’Amore!!!! Adorable home less than 1/2 mile from downtown Clarksdale](//images.trvl-media.com/lodging/114000000/113250000/113243700/113243634/467c648a_y.jpg) ### Casa D’Amore!!!! Adorable home less than 1/2 mile from downtown Clarksdale 10/10 Excellent "The house was amazing!!! Super comfy bed, the place was immaculate, quiet neighborhood and the hosts supplied everything we needed for our stay. It is a short walk to town but because of the rain we drove. Definitely will stay again." [](https://expedia.ca/Clarksdale-Hotels-Charming-2-Bedroom-House-In-Lovely-Clarksdale-With-WiFi.h113243634.Hotel-Information) ![Quality Inn](//images.trvl-media.com/lodging/1000000/160000/151300/151227/766fdf07_y.jpg) ### Quality Inn 10/10 Excellent "Clean room and friendly staff. Comfortable bed. One thing I may add is get bigger pillows for the beds. The little 4 square pillows don't make for good sleep. Other than that, all good. Thanks." [](https://expedia.ca/Clarksdale-Hotels-Quality-Inn.h151227.Hotel-Information) ![Only a mile from historic downtown Clarksdale!](//images.trvl-media.com/lodging/77000000/76040000/76031100/76031053/ecc9aaad_y.jpg) ### Only a mile from historic downtown Clarksdale! 10/10 Excellent "The cottage was excellent. I would recommend staying there." [](https://expedia.ca/Clarksdale-Hotels-Only-A-Mile-From-Historic-Downtown-Clarksdale.h76031053.Hotel-Information) ![Get to BLUES-in' at Rusty's Roost, adjacent to downtown Clarksdale, MS](//images.trvl-media.com/lodging/102000000/101150000/101144900/101144826/12bbff96_y.jpg) ### Get to BLUES-in' at Rusty's Roost, adjacent to downtown Clarksdale, MS 10/10 Excellent "The house was spotless, neat and organized. Thank you for truly making your home feel like home. The shower was amazing with great water pressure, plenty of hot water and the curtain was properly hung so there was no excess material being soaked in the shower bed. The personal amenities that were provided for your use was a nice addition with lush towels. We slept in the back bedroom which was very comfortable with nice linens. Also we did appreciate the washer/dryer as we were continuing in with our travels. The area was very quiet and it was a short distance to drive to the downtown area. We had the pleasure of meeting Robin and Jessica via text was very responsive and helpful. Don’t hesitate to stay here!" [](https://expedia.ca/Clarksdale-Hotels-Get-To-BLUES-In-At-Rustys-Roost.h101144826.Hotel-Information) ![Americas Best Value Inn & Suites Clarksdale](//images.trvl-media.com/lodging/1000000/160000/151300/151226/c0e992b8_y.jpg) ### Americas Best Value Inn & Suites Clarksdale 10/10 Excellent "Good location in town" [](https://expedia.ca/Clarksdale-Hotels-Americas-Best-Value-Inn-Suites-Clarksdale.h151226.Hotel-Information) ![Hampton Inn Clarksdale](//images.trvl-media.com/lodging/9000000/8280000/8273700/8273622/e34ceb08_y.jpg) ### Hampton Inn Clarksdale 10/10 Excellent "The staff was so pleasant and friendly The entire visit was very nice " [](https://expedia.ca/Clarksdale-Hotels-Hampton-Inn-Clarksdale.h8273622.Hotel-Information) ![Cottage on riverbank one mile from Clarksdale in gated community](//images.trvl-media.com/lodging/79000000/79000000/78996000/78995934/9f913091_y.jpg) ### Cottage on riverbank one mile from Clarksdale in gated community 10/10 Excellent "Great location - peaceful and private but only a couple of miles to downtown. Very clean and comfortable. Hope to come again. " [](https://expedia.ca/Clarksdale-Hotels-Cottage-On-The-Sunflower-River.h78995934.Hotel-Information) ![Travelers Hotel](//images.trvl-media.com/lodging/35000000/34870000/34868100/34868083/cc59a6f5_y.jpg) ### Travelers Hotel 10/10 Excellent "Solid room, good service, great location. It was a relatively new hotel as if sept 2025 so some of the amenities were still being rolled out." [](https://expedia.ca/Clarksdale-Hotels-Travelers-Hotel.h34868083.Hotel-Information) ![Sunset Log Cabin](//images.trvl-media.com/lodging/97000000/96760000/96758600/96758575/07f49a54_y.jpg) ### Sunset Log Cabin 10/10 Excellent "Libby is the perfect host. She has a few different places and the cabin is the second I’ve rented. Loved it. The screened in porch is an amazing place to enjoy morning coffee or anytime really. And like Libby’s other places it’s a short drive into Clarksdale. I would absolutely stay here again. " [](https://expedia.ca/Clarksdale-Hotels-Sunset-Log-Cabin.h96758575.Hotel-Information) ## Find out more about Lyon ## Lyon Vacation Homes information | Number of reviews | 19 | | --- | --- | | Accommodation | 4 Vacation Homes | | Lowest Price | CA $287 | | Highest Price | CA $304 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Alligator Hotels](https://www.expedia.ca/Alligator-Hotels.d553248635975866196.Travel-Guide-Hotels) - [Villas in Alligator](https://www.expedia.ca/Alligator-Villas.d553248635975866196-aaVillas.Travel-Guide-Accommodation) - [Cabin Rentals in Batesville](https://www.expedia.ca/Batesville-Cabins.d6711-aaCabins.Travel-Guide-Accommodation) - [Motels in Batesville](https://www.expedia.ca/Batesville-Motels.d6711-aaMotels.Travel-Guide-Accommodation) - [Hotels near Bologna Performing Arts Center](https://www.expedia.ca/Bologna-Performing-Arts-Center-Hotels.0-l553248621532644997-0.Travel-Guide-Filter-Hotels) - [Charleston Hotels](https://www.expedia.ca/Charleston-Hotels.d553248634999355364.Travel-Guide-Hotels) - 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