Lyon Vacation Rentals

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Lyon vacation rentals

Sunset Log Cabin

Sunset Log Cabin
Clarksdale
9.8 out of 10, Exceptional, (19 reviews)
"Libby is the perfect host. She has a few different places and the cabin is the second I’ve rented. Loved it. The screened in porch is an amazing place to enjoy morning coffee or anytime really. And like Libby’s other places it’s a short drive into Clarksdale. I would absolutely stay here again. "
United States
Diane W.
The price is CA $155
CA $253 total
includes taxes & fees
Feb 18 - Feb 19
Sunset Log Cabin

Only a mile from historic downtown Clarksdale!

Only a mile from historic downtown Clarksdale!
Clarksdale
10.0 out of 10, Exceptional, (22 reviews)
"It is the best place to stay in Clarksdale. A delightful setting, a charming little cabin and John is a great host."
United States
Philip H.
The price is CA $203
CA $271 total
includes taxes & fees
Feb 18 - Feb 19
Only a mile from historic downtown Clarksdale!

Cottage on riverbank one mile from Clarksdale in gated community

Cottage on riverbank one mile from Clarksdale in gated community
Clarksdale
8.8 out of 10, Excellent, (11 reviews)
"Great location - peaceful and private but only a couple of miles to downtown. Very clean and comfortable. Hope to come again. "
United States
Don G.
The price is CA $186
CA $309 total
includes taxes & fees
Mar 1 - Mar 2
Cottage on riverbank one mile from Clarksdale in gated community

Charming 1-bedroom house in fabulous Clarksdale with WiFi

Charming 1-bedroom house in fabulous Clarksdale with WiFi
Clarksdale
The price is CA $205
CA $282 total
includes taxes & fees
Feb 20 - Feb 21
Charming 1-bedroom house in fabulous Clarksdale with WiFi

The Sunflower Penthouse on the River in Clarksdale

The Sunflower Penthouse on the River in Clarksdale
Clarksdale
9.2 out of 10, Wonderful, (21 reviews)
"Beautiful setting very close to the town of blues! Beds were very comfortable & outdoor seating was lovely ! I would recommend staying there for a comfortable & convenient visit to Clarksdsle!"
United States
Mary B.
The price is CA $174
CA $294 total
includes taxes & fees
Feb 22 - Feb 23
The Sunflower Penthouse on the River in Clarksdale

Modern Lambert Apartment

Modern Lambert Apartment
Lambert
The price is CA $3,955
CA $4,783 total
includes taxes & fees
Feb 22 - Feb 23
Modern Lambert Apartment
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.
Save an average of 15% on thousands of hotels when you're signed in

Top Lyon Hotel Reviews

Find out more about Lyon

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Lyon. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Are there vacation rentals in Lyon?

Yes, we give you a choice of vacation rentals close to the most popular local attractions in Lyon, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best vacation rentals that Lyon has to offer?

Casa D’Amore!!!! Adorable home less than 1/2 mile from downtown Clarksdale: Visitors like this Lyon vacation home rental. It is equipped with a fireplace, air-conditioning, and laundry facilities to help you feel comfortable during your stay. Kitchen amenities include a fridge, a stovetop, and a microwave.

What can I see and do in Lyon?

Delta Blues Museum and Rock N' Roll & Blues Heritage Museum are a couple of family-friendly sights to visit in the area. In the larger area, you’ll find Ground Zero Blues Club and Coahoma Community College.

What are vacation rentals like in Lyon?

Vacation rentals are privately owned properties you can reserve for a few days or a quick weekend in Lyon. Vacation rentals offer amenities such as WiFi and washers and dryers so you'll feel just like you're staying in your own home. If you're concerned about cleanliness, a vacation rental can offer a sense of security away from shared hotel elevators and busy reception areas while still allowing you to travel. You'll also get more space in a vacation rental than in a hotel, which makes a vacation rental a great option for a family trip.