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A historic building with ornate architecture, including columns and decorative moldings.

Find hotels near Kentucky Science Center, Louisville from CA $145

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    Check prices for these dates, December 14–15, 2026

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    Our top choices for Kentucky Science Center hotels

    1. Market Street Inn

    An outdoor patio area with round tables and chairs, surrounded by potted plants and a brick chimney.

    2. Hotel Distil, Autograph Collection

    A restaurant with a high ceiling, exposed brick walls, hanging plants, and a variety of seating arrangements.

    3. The Brown Hotel

    A grand lobby with ornate columns, plush seating, and a chandelier.

    4. Homewood Suites by Hilton Louisville Downtown, KY

    An outdoor patio area with seating, a fire pit, and a pergola with string lights.

    5. The Grady

    A modern interior with leather sofas, a bookshelf, and a decorative wall with 'The Grady' sign.

    6. DuPont Mansion Bed & Breakfast

    A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.

    7. Tempo By Hilton Louisville Downtown Nulu

    An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.

    8. Omni Louisville Hotel

    A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.

    9. 21c Museum Hotel Louisville

    A steam fountain in a brick alleyway.

    10. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

    A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.

    11. Stellar Suites

    A modern building with a sign for "Stellar Suites."

    12. Cambria Hotel Louisville Downtown-Whiskey Row

    A horse statue with a plaque in a modern interior space with a dining area and large windows.

    13. Central Park Bed & Breakfast

    A covered patio with a stone wall, a glass table, and a bench.

    14. Towneplace Suites By Marriott Louisville Downtown

    A modern lounge area with seating, tables, and a view of the city through large windows.

    15. Moxy Louisville Downtown

    A cozy living room with a fireplace, a black leather sofa, and a patterned rug.

    16. Aloft by Marriott Louisville Downtown

    A bar with multiple shelves of liquor bottles and glasses.

    17. Hotel Genevieve part of JdV by Hyatt

    A bar area with a neon sign, red seating, and a bar counter.

    18. AC Hotel Louisville Downtown

    Courtyard

    19. Galt House Hotel Trademark Collection by Wyndham

    A modern interior with large windows offering a city view, a circular light fixture, and leather seating.

    20. Embassy Suites Louisville Downtown

    A building with a sign reading "Embassy Suites."

    Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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    Compare popular hotels close to Kentucky Science Center

    PropertyStar ratingGuest ratingBreakfast includedPoolSpaPet-friendlyWiFi included
    An outdoor patio area with round tables and chairs, surrounded by potted plants and a brick chimney.
    Market Street Inn
    9.8Exceptional127 reviewsView
    A restaurant with a high ceiling, exposed brick walls, hanging plants, and a variety of seating arrangements.
    Hotel Distil, Autograph Collection
    9.6Exceptional520 reviewsView
    A grand lobby with ornate columns, plush seating, and a chandelier.
    The Brown Hotel
    9.4Exceptional1,482 reviewsView
    An outdoor patio area with seating, a fire pit, and a pergola with string lights.
    Homewood Suites by Hilton Louisville Downtown, KY
    9.4Exceptional1,004 reviewsView
    A modern interior with leather sofas, a bookshelf, and a decorative wall with 'The Grady' sign.
    The Grady
    9.4Exceptional1,003 reviewsView

    Other attractions near Kentucky Science Center

    A tall wooden baseball bat leaning against a brick building with a sign reading "Hillerich & Brassler Co."

    Louisville Slugger Museum

    Rating: 9.2/10 (2,299 reviews)

    Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.

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    A modern building with a cylindrical structure and a glass facade.

    Muhammad Ali Center

    Rating: 8.8/10 (295 reviews)

    One of the world’s greatest boxers continues providing inspiration beyond the world of sport. Understand this superstar by visiting this center honoring him.

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    The Frazier History Museum with red doors and a tree in front.

    Frazier History Museum

    Rating: 9.4/10 (10 reviews)

    Get to know Louisville with a visit to this esteemed museum. It’s a great spot for social interaction as well.

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    The Kentucky Center for the Performing Arts building facade with large glass windows and a prominent sign.

    Kentucky Center for the Performing Arts

    Rating: 8.8/10 (49 reviews)

    Enjoy a pleasant night at the opera or attend a concert, live dance or stage production at this glass-fronted venue in downtown Louisville.

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    KMAC Contemporary Art Museum

    You can spend an afternoon exploring the galleries in Kentucky Museum of Art and Craft during your travels in Louisville. Stroll along the area's riverfront or experience its lively festivals.

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    Golden Statue of David

    Find out about the history of Louisville when you take a trip to Golden Statue of David. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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    SAR Genealogical Research Library: NSSAR Library

    You can spend an afternoon browsing the exhibits at SAR Genealogical Research Library: NSSAR Library in Louisville. Amble around this family-friendly area's riverfront and enjoy its top-notch restaurants.

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    Top Kentucky Science Center Hotel Reviews

    Derby City Gaming & Hotel - A Churchill Downs Property (Adults Only)

    A bar area with multiple seating options and a large display of liquor bottles.

    The Grady

    A modern interior with leather sofas, a bookshelf, and a decorative wall with 'The Grady' sign.

    Omni Louisville Hotel

    A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.

    The Brown Hotel

    A grand lobby with ornate columns, plush seating, and a chandelier.

    Hilton Garden Inn Jeffersonville Louisville North

    An indoor dining area with tables and chairs, large windows, and a brick wall.

    Drury Inn & Suites Louisville North

    A Drury Inn & Suites hotel with a covered entrance, multiple floors, and a parking area.

    Homewood Suites by Hilton Louisville-East

    A compact hotel room with a kitchenette, a small dining area, a bed, and a bedside table with a lamp.

    Towneplace Suites By Marriott Louisville Downtown

    A modern lounge area with seating, tables, and a view of the city through large windows.

    Cambria Hotel Louisville Downtown-Whiskey Row

    A horse statue with a plaque in a modern interior space with a dining area and large windows.

    Moxy Louisville Downtown

    A cozy living room with a fireplace, a black leather sofa, and a patterned rug.

    Aloft by Marriott Louisville Downtown

    A bar with multiple shelves of liquor bottles and glasses.

    Frequently Asked Questions

    What's the area like around Louisville Science Center?

    Louisville Science Center is located in an area of Louisville known for its beautiful river views, sporting events, and great live music scene. If you're looking for a convenient place to stay, check out the 292 hotels and other accommodations you'll find within a mile.

    What's the best place to stay near Louisville Science Center?

    Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a 24-hour fitness center. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.

    How many hotels can I expect to find close to Louisville Science Center?

    Expedia has 292 hotels and other accommodations within a mile from Louisville Science Center.

    If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?

    Yes, you'll find most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to review the best deals near Louisville Science Center.

    Where can I learn more about changing or cancelling my trip in the area near Louisville Science Center?

    For more details about picking new dates or cancelling your stay near Louisville Science Center, click here.

    What can I see and do near Louisville Science Center?

    21c Museum Hotel, Louisville Slugger Museum, and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row, and Big Four Bridge. You can catch a show at Louisville Palace, Derby Dinner Playhouse, and Headliners Music Hall.

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