Isle Casino Cape Girardeau Tours and Activities

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Popular places to visit

Image for Southeast Missouri State University

Southeast Missouri State University

Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.

Southeast Missouri State University
Image for Show Me Center

Show Me Center

Catch an event at Show Me Center during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.

Show Me Center
Image for eDen Spa & Salon

eDen Spa & Salon

You can take time to visit eDen Spa & Salon during your travels to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.

eDen Spa & Salon
Image for Riverfront Park

Riverfront Park

Explore the great outdoors at Riverfront Park, a lovely green space in Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.

Riverfront Park
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Riverfront Bridge Park

5/5(1 review)

Explore the great outdoors at Riverfront Bridge Park, a lovely green space in Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.

Riverfront Bridge Park
Image for Southeast Missouri Hospital

Southeast Missouri Hospital

Though Southeast Missouri Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Cape Girardeau while you are here.

Southeast Missouri Hospital

Best Lodging Options Near Isle Casino Cape Girardeau

Auburn Place Hotel And Suites
Auburn Place Hotel And Suites
2.5 out of 5
3265 William St, Cape Girardeau, MO
Auburn Place Hotel And Suites
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
Pear Tree Inn Cape Girardeau West
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
2.5 out of 5
3253 William Street, Cape Girardeau, MO
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
3 out of 5
3351 Percy Drive, Cape Girardeau, MO
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
3 out of 5
3303 Campster Drive, Cape Girardeau, MO
Drury Inn & Suites Cape Girardeau
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 out of 5
3248 William St, Cape Girardeau, MO
Pear Tree Inn Cape Girardeau Near the Medical Center
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
Cape Girardeau
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
Little Blue Cottage on Spanish
Little Blue Cottage on Spanish
Cape Girardeau
Little Blue Cottage on Spanish
Loft Apartment Across From Semo University Houch Field House. Walk To Events
Loft Apartment Across From Semo University Houch Field House. Walk To Events
Cape Girardeau
Loft Apartment Across From Semo University Houch Field House. Walk To Events
See all 220 properties in Isle Casino Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.