Title: East Prairie Condo Rentals from CA $91 | Expedia.ca [Hotels in East Prairie](https://expedia.ca/East-Prairie-Hotels.d3000349349.Travel-Guide-Hotels)[Vacation Rentals in East Prairie](https://expedia.ca/East-Prairie-Vacation-Rentals.d3000349349.Travel-Guide-VacationRentals)[East Prairie Car Rentals](https://expedia.ca/Car-Rentals-In-East-Prairie.d3000349349.Car-Rental-Guide)[East Prairie Vacation Packages](https://expedia.ca/East-Prairie.d3000349349.Destination-Travel-Guides) ![Lodging Image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=3000349349&startDate=2026-02-20&endDate=2026-02-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Apr 3 - Apr 5](https://www.expedia.ca/Hotel-Search?regionId=3000349349&startDate=2026-04-03&endDate=2026-04-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [May 1 - May 3](https://www.expedia.ca/Hotel-Search?regionId=3000349349&startDate=2026-05-01&endDate=2026-05-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [May 29 - May 31](https://www.expedia.ca/Hotel-Search?regionId=3000349349&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) No exact matches found, but these alternatives could be just right ## Recommended hotels in East Prairie ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/85184a8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/978331d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/f90ef358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Sikeston, MO [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) Sikeston 9.4/10 Exceptional (1,001 reviews) "As always it was a perfect visit" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $123 CA $141 total includes taxes & fees Feb 12 - Feb 13 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/39000000/38310000/38309600/38309567/2a51d3d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/39000000/38310000/38309600/38309567/54eabc09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/39000000/38310000/38309600/38309567/e89ec295.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/39000000/38310000/38309600/38309567/55808580.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn at Discovery Park of America [](https://www.expedia.ca/Union-City-Hotels-Sleep-Inn.h38309567.Hotel-Information) Union City 9.2/10 Wonderful (340 reviews) "The rooms are big and the property is spotless!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) debbie CA $103 CA $123 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/Union-City-Hotels-Sleep-Inn.h38309567.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/1fd79e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/3aa729da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8 AM to 11 PM, sun loungers](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/65f9cbe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/58cb82c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Sikeston Southwest by IHG [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) Sikeston 8.6/10 Excellent (447 reviews) "Stay was excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kourtney CA $137 CA $155 total includes taxes & fees Feb 13 - Feb 14 [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/4abadc7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, free WiFi, bed sheets](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/cbe2898d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Sikeston [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) Sikeston 9.0/10 Wonderful (474 reviews) "Great place for an overnight stay. I will be back!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jenny CA $133 CA $151 total includes taxes & fees Feb 23 - Feb 24 [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/970000/969900/969839/7bc13d14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/970000/969900/969839/c5b64e33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/970000/969900/969839/7397c7ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/970000/969900/969839/3fa32ded.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Hearth Inn & Suites Union City [](https://www.expedia.ca/Union-City-Hotels-Country-Hearth-Inn-Suites-Union-City.h969839.Hotel-Information) Union City 8.6/10 Excellent (552 reviews) "Very clean nice staff and well run " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) zach CA $98 CA $117 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Union-City-Hotels-Country-Hearth-Inn-Suites-Union-City.h969839.Hotel-Information) ![Individually decorated, individually furnished, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/47690ac7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/bf40a512.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/d5d0cfa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) [](https://www.expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) Sikeston 8.4/10 Very good (735 reviews) "Room was clean. Fairly quiet room. Front desk was kind. Would stay here again. ." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Becky CA $80 CA $91 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Room, 1 Queen Bed, Non Smoking](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/5b4d84d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/7d06bc03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/0acd5e5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/e6403655.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 By Wyndham Marston [](https://www.expedia.ca/Marston-Hotels-Super-8-By-Wyndham-Marston.h108416635.Hotel-Information) Marston 8.0/10 Very good (45 reviews) "Great hotel, great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dmitry CA $89 CA $101 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Marston-Hotels-Super-8-By-Wyndham-Marston.h108416635.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/f2cf9c54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/27c728aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/e959f8b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/7d2010d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Sikeston [](https://www.expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) Sikeston 9.2/10 Wonderful (55 reviews) "Clean rooms great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) IRA CA $138 CA $156 total includes taxes & fees Feb 19 - Feb 20 [](https://www.expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/327b8d22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (with Sofabed)](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/b775798e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/42667f54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Sikeston I-55 [](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) Sikeston 8.4/10 Very good (1,004 reviews) "Great stay, everything was clean and comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles CA $116 CA $132 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Premier Room, 1 Bedroom, Non Smoking](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/2d9e6936.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Room, 1 Bedroom, Non Smoking | Bathroom](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/5fa7b845.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, free toiletries, towels, soap](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/1d8642af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/a77daa89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### New Orleans Inn Portageville [](https://www.expedia.ca/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information) Portageville 8.0/10 Very good (739 reviews) "Parking was good, staff was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Corey [](https://www.expedia.ca/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/20000/14600/14571/c1609da5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14600/14571/bfe56101.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/14600/14571/ba65d6e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/14600/14571/643f6c59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Union City US 51 [](https://www.expedia.ca/Union-City-Hotels-Quality-Inn-Union-City-US-51.h14571.Hotel-Information) Union City 8.4/10 Very good (493 reviews) "Nice room" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) José Ricardo CA $92 CA $109 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/Union-City-Hotels-Quality-Inn-Union-City-US-51.h14571.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/4d49b58b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/70102e04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/7498b763.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Riverstone Hotel [](https://www.expedia.ca/Charleston-Hotels-The-Riverstone-Hotel.h20594.Hotel-Information) Charleston 6.8/10 (408 reviews) "The staff was very friendly and accommodating " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Arturo CA $96 CA $106 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Charleston-Hotels-The-Riverstone-Hotel.h20594.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/40000000/39580000/39579100/39579081/c970f53d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/40000000/39580000/39579100/39579081/2feca880.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/40000000/39580000/39579100/39579081/aadd65c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/40000000/39580000/39579100/39579081/832ea567.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Union City by IHG [](https://www.expedia.ca/Union-City-Hotels-Holiday-Inn-Express-Suites-Union-City.h39579081.Hotel-Information) Union City 9.4/10 Exceptional (313 reviews) "The room was spacious & clean. The complimentary breakfast was nice. Very quiet place and next to a unique tourist attraction." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela CA $145 CA $173 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Union-City-Hotels-Holiday-Inn-Express-Suites-Union-City.h39579081.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/71000000/70820000/70814800/70814746/f7d6d20c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible (Hearing)](https://images.trvl-media.com/lodging/71000000/70820000/70814800/70814746/f54017fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/71000000/70820000/70814800/70814746/2c1de1a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/71000000/70820000/70814800/70814746/8df1e765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Union City [](https://www.expedia.ca/Union-City-Hotels-Hampton-Inn-Union-City.h70814746.Hotel-Information) Union City 9.6/10 Exceptional (170 reviews) "Spotless , friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gail CA $151 CA $180 total includes taxes & fees Feb 13 - Feb 14 [](https://www.expedia.ca/Union-City-Hotels-Hampton-Inn-Union-City.h70814746.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/f1c41457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/e2b2c624.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/74187a0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/9d3e181d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cairo I-57 [](https://www.expedia.ca/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) Cairo 6.6/10 (276 reviews) "The quality was not what I expected for a "Quality Inn". It felt more light a Motel 6\. I was not satisfied at all." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ReShena CA $93 CA $103 total includes taxes & fees Mar 6 - Mar 7 [](https://www.expedia.ca/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) ![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/be0d2e33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/3d86dbb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/7335ffbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/8fe9a2cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn and Suites by Wyndham Sikeston [](https://www.expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) Sikeston 7.2/10 Good (1,001 reviews) "Everything was excellent" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James CA $93 CA $106 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/679acee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/a5038447.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/bbf96e9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Charleston/Sikeston East MO [](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) Charleston 6.8/10 (622 reviews) "Affordable for a quick one night stay. Restaurant and gas station next to hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Annette CA $85 CA $94 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w3995h2667x0y0-6f8601de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/de7767c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w4000h2662x0y0-82d0e62d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed with Sofa bed](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w3995h2667x0y0-c8905780.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Sikeston [](https://www.expedia.ca/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) Sikeston 9.2/10 Wonderful (12 reviews) "Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scott CA $197 CA $223 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) ![Desk, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/4da73ae3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/7657c6fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/7a78d337.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/1fa29b5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Sikeston I-55 [](https://www.expedia.ca/Sikeston-Hotels-Comfort-Inn-Suites-Sikeston-I-55.h1804447.Hotel-Information) Sikeston 8.4/10 Very good (286 reviews) "The hotel was very clean, beds were comfortable, and staff was friendly and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) aileen CA $118 CA $135 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Sikeston-Hotels-Comfort-Inn-Suites-Sikeston-I-55.h1804447.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/123000000/122910000/122905300/122905281/3df6bc42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/123000000/122910000/122905300/122905281/93527246.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/123000000/122910000/122905300/122905281/w1170h1560x0y486-d4d3ef58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122910000/122905300/122905281/f9ad8a19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tranquil charming Tiny House in Clinton [](https://www.expedia.ca/Clinton-Hotels-Tranquil-Charming-Tiny-House-In-Clinton.h122905281.Hotel-Information) Clinton 10/10 Exceptional (1 review) "Super clean and comfortable. We were in the area visiting family and were so happy to find this rental. Very clean, comfortable beds, great sheets and towels. Thank you Zack and Tiff for opening your cute little rental to us. We hope you’re not booked when we return. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laura K. CA $123 CA $205 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Clinton-Hotels-Tranquil-Charming-Tiny-House-In-Clinton.h122905281.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-21&endDate=2026-02-22®ionId=3000349349&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find vacation rentals that suit your style Private vacation homes [](https://www.expedia.ca/Hotel-Search?destination=East+Prairie%2C+Missouri%2C+United+States+of+America®ionId=3000349349&latLong=36.779778%2C-89.38563&adults=2&startDate=2026-05-08&d1=2026-05-08&endDate=2026-05-11&d2=2026-05-11&lodging=VACATION_HOME) Cabins [](https://www.expedia.ca/Hotel-Search?destination=East+Prairie%2C+Missouri%2C+United+States+of+America®ionId=3000349349&latLong=36.779778%2C-89.38563&adults=2&startDate=2026-05-08&d1=2026-05-08&endDate=2026-05-11&d2=2026-05-11&lodging=CABIN) Cottages [](https://www.expedia.ca/Hotel-Search?destination=East+Prairie%2C+Missouri%2C+United+States+of+America®ionId=3000349349&latLong=36.779778%2C-89.38563&adults=2&startDate=2026-05-08&d1=2026-05-08&endDate=2026-05-11&d2=2026-05-11&lodging=COTTAGE) Apartments [](https://www.expedia.ca/Hotel-Search?destination=East+Prairie%2C+Missouri%2C+United+States+of+America®ionId=3000349349&latLong=36.779778%2C-89.38563&adults=2&startDate=2026-05-08&d1=2026-05-08&endDate=2026-05-11&d2=2026-05-11&lodging=APARTMENT) Condos [](https://www.expedia.ca/Hotel-Search?destination=East+Prairie%2C+Missouri%2C+United+States+of+America®ionId=3000349349&latLong=36.779778%2C-89.38563&adults=2&startDate=2026-05-08&d1=2026-05-08&endDate=2026-05-11&d2=2026-05-11&lodging=CONDO) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FEast-Prairie-Condos.d3000349349-aaCondos.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FEast-Prairie-Condos.d3000349349-aaCondos.Travel-Guide-Accommodation) ## Top East Prairie Hotel Reviews ![Fairfield Inn & Suites by Marriott Sikeston](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/cffe72cf_y.jpg) ### Fairfield Inn & Suites by Marriott Sikeston 10/10 Excellent "Clean rooms great staff" [](https://expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Hampton Inn Union City](https://images.trvl-media.com/lodging/71000000/70820000/70814800/70814746/f7d6d20c_y.jpg) ### Hampton Inn Union City 10/10 Excellent "Spotless , friendly staff." [](https://expedia.ca/Union-City-Hotels-Hampton-Inn-Union-City.h70814746.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Clean room and shower, ruffled hotel toilet paper, dinner buffet, breakfast buffet, hot tub and pool. And pets are welcome. Great service and great value. " [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Holiday Inn Express & Suites Union City by IHG](https://images.trvl-media.com/lodging/40000000/39580000/39579100/39579081/c9703c12_y.jpg) ### Holiday Inn Express & Suites Union City by IHG 10/10 Excellent "The room was spacious & clean. The complimentary breakfast was nice. Very quiet place and next to a unique tourist attraction." [](https://expedia.ca/Union-City-Hotels-Holiday-Inn-Express-Suites-Union-City.h39579081.Hotel-Information) ![Best Western Plus Sikeston](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg) ### Best Western Plus Sikeston 10/10 Excellent "Great breakfast. Clean room Quiet" [](https://expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea_y.jpg) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) 10/10 Excellent "Room was clean. Fairly quiet room. Front desk was kind. Would stay here again. ." [](https://expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Great location just across the street from Reelfoot Lake close to boat ramps](https://images.trvl-media.com/lodging/90000000/89880000/89872800/89872735/96df576d_y.jpg) ### Great location just across the street from Reelfoot Lake close to boat ramps 10/10 Excellent "Everything was good" [](https://expedia.ca/Hornbeak-Hotels-Great-Location-Just-Across-The-Street-From-Reelfoot-Lake-Close-To-Boat-Ramps.h89872735.Hotel-Information) ![Sleep Inn at Discovery Park of America](https://images.trvl-media.com/lodging/39000000/38310000/38309600/38309567/2a51d3d0_y.jpg) ### Sleep Inn at Discovery Park of America 10/10 Excellent "The room was clean as usual! The staff always go above and beyond!" [](https://expedia.ca/Union-City-Hotels-Sleep-Inn.h38309567.Hotel-Information) ![New Orleans Inn Portageville ](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/2d9e6936_y.jpg) ### New Orleans Inn Portageville 10/10 Excellent "Excelente y solidarios " [](https://expedia.ca/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information) ## Find out more about East Prairie ## East Prairie Condo Rentals information | Number of reviews | 8,960 | | ----------------- | --------------- | | Accommodation | 2 Condo Rentals | | Lowest Price | CA $91 | | Highest Price | CA $223 | ## Explore a world of travel with Expedia - Lodging - Flights - Cars - More ways to book - [B&B in Advance ](https://www.expedia.ca/Advance-Bed-And-Breakfast.d553248634983475122-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Lodges in Advance ](https://www.expedia.ca/Advance-Lodges.d553248634983475122-aaLodges.Travel-Guide-Accommodation) - [Motels in Advance ](https://www.expedia.ca/Advance-Motels.d553248634983475122-aaMotels.Travel-Guide-Accommodation) - 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