Title: Book the Best Central Missouri SPA Resorts - Spa Hotels in Central Missouri, MO | Expedia.ca [Central Missouri Travel Guide](https://expedia.ca/Central-Missouri.dx6058776)[Hotels in Central Missouri](https://expedia.ca/Central-Missouri-Hotels.d6058776.Travel-Guide-Hotels)[Vacation Rentals in Central Missouri](https://expedia.ca/Central-Missouri-Vacation-Rentals.d6058776.Travel-Guide-VacationRentals)[Flights to Central Missouri](https://expedia.ca/Cheap-Flights-To-Central-Missouri.d6058776.Travel-Guide-Flights)[Things to do in Central Missouri](https://expedia.ca/Things-To-Do-In-Central-Missouri.d6058776.Travel-Guide-Activities)[Central Missouri Car Rentals](https://expedia.ca/Car-Rentals-In-Central-Missouri.d6058776.Car-Rental-Guide)[Central Missouri Vacation Packages](https://expedia.ca/Central-Missouri.d6058776.Destination-Travel-Guides) ![Columbia featuring wild flowers](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/257000/257714-Central-Missouri.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Central Missouri, MO ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Central Missouri Spa Hotels Tonight [Oct 30 - Oct 31](https://www.expedia.ca/Hotel-Search?regionId=6058776&startDate=2025-10-30&endDate=2025-10-31&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 31 - Nov 1](https://www.expedia.ca/Hotel-Search?regionId=6058776&startDate=2025-10-31&endDate=2025-11-01&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6058776&startDate=2025-10-31&endDate=2025-11-02&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6058776&startDate=2025-11-07&endDate=2025-11-09&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Central Missouri Spa Hotels ![Couples treatment rooms, hot tub, body treatments, hydrotherapy](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/4d290838.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7e36eb59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/d106f50c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/41084352.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lodge Of Four Seasons Golf Resort, Marina & Spa Lake Ozark 7.4/10 Good (1047) "Great place go all the time" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) cale CA $113 CA $156 total includes taxes & fees Nov 20 - Nov 21 [](https://www.expedia.ca/Osage-Beach-Hotels-Lodge-Of-Four-Seasons-Golf-Resort.h40728.Hotel-Information) ![Couples treatment rooms, body treatments, hydrotherapy, aromatherapy](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/7d41cdab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; Caribbean cuisine](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/926b808f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/b09c0391.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, sun loungers](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/21eb378b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Camden on the Lake Resort & Spa Lake Ozark 9.0/10 Wonderful (1002) "Friendly staff, Beautiful facilities. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary [](https://www.expedia.ca/Osage-Beach-Hotels-Camden-On-The-Lake-Resort-Spa.h2015357.Hotel-Information) ![Couples treatment rooms, steam room, body treatments](https://images.trvl-media.com/lodging/10000000/9790000/9785300/9785264/c54d3975.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/10000000/9790000/9785300/9785264/64c8ff64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/10000000/9790000/9785300/9785264/bfd40943.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/10000000/9790000/9785300/9785264/8d3e409f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lodge at Old Kinderhook Golf Resort Camdenton 9.4/10 Exceptional (734) "Easy access, fast friendly check in and excellent Accommodations." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard CA $250 CA $291 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/Osage-Beach-Hotels-The-Lodge-At-Old-Kinderhook-Golf-Resort.h9785264.Hotel-Information) ![Sundeck](https://images.trvl-media.com/lodging/1000000/30000/21300/21228/268207dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, iron/ironing board, travel crib, free WiFi](https://images.trvl-media.com/lodging/1000000/30000/21300/21228/83344a11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21300/21228/e7bd5e4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/21300/21228/d8a21312.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Margaritaville Lake Resort Lake of the Ozarks Osage Beach 8.4/10 Very good (1000) "Excellent property, great staff clean and spacious rooms at a great location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Martin CA $158 CA $199 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Osage-Beach-Hotels-Margaritaville-Lake-Resort-Lake-Of-The-Ozarks.h21228.Hotel-Information) ![Couples treatment rooms, body treatments, aromatherapy](https://images.trvl-media.com/lodging/2000000/1550000/1545200/1545110/1a33bfc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1550000/1545200/1545110/f663be7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1550000/1545200/1545110/c5b42c11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/2000000/1550000/1545200/1545110/9e770f7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Courtland Hotel and Day Spa Fort Scott 9.2/10 Wonderful (269) "This is a great place to stay and with easy access to town area!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark CA $105 CA $122 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Pittsburg-Hotels-The-Courtland-Hotel-And-Day-Spa.h1545110.Hotel-Information) ![Couples treatment rooms, aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/2000000/1670000/1664700/1664659/f1ee0a61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1670000/1664700/1664659/e45a31c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Spa Suite | View from room](https://images.trvl-media.com/lodging/2000000/1670000/1664700/1664659/34923626.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Spa Suite](https://images.trvl-media.com/lodging/2000000/1670000/1664700/1664659/1f413a42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hermann Hill Hermann 9.6/10 Exceptional (109) "Top notch they think of everything. Highly recommend. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kevin CA $485 CA $558 total includes taxes & fees Nov 13 - Nov 14 [](https://www.expedia.ca/Washington-Hotels-Hermann-Hill.h1664659.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-14&endDate=2025-11-15®ionId=6058776&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Central Missouri Hotel Reviews ![Wingate by Wyndham - Columbia](//images.trvl-media.com/lodging/1000000/990000/986100/986086/a16387a6_y.jpg) ### Wingate by Wyndham - Columbia 10/10 Excellent "😊" [](https://expedia.ca/Columbia-Hotels-Wingate-By-Wyndham-Columbia.h986086.Hotel-Information) ![Stoney Creek Hotel Columbia](//images.trvl-media.com/lodging/2000000/1060000/1052400/1052330/5398551a_y.jpg) ### Stoney Creek Hotel Columbia 10/10 Excellent "Great place " [](https://expedia.ca/Columbia-Hotels-Stoney-Creek-Hotel-Columbia.h1052330.Hotel-Information) ![Days Inn by Wyndham Osage Beach Lake of the Ozarks](//images.trvl-media.com/lodging/1000000/20000/18400/18390/b506b22f_y.jpg) ### Days Inn by Wyndham Osage Beach Lake of the Ozarks 10/10 Excellent "Good" [](https://expedia.ca/Osage-Beach-Hotels-Days-Inn-By-Wyndham-Osage-Beach-Lake-Of-The-Ozarks.h18390.Hotel-Information) ![Country Inn & Suites by Radisson, Columbia, MO](//images.trvl-media.com/lodging/2000000/1660000/1658500/1658463/c8809092_y.jpg) ### Country Inn & Suites by Radisson, Columbia, MO 10/10 Excellent "Great people + great place = excellent stay" [](https://expedia.ca/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h1658463.Hotel-Information) ![Lodge Of Four Seasons Golf Resort, Marina & Spa](//images.trvl-media.com/lodging/1000000/50000/40800/40728/7e36eb59_y.jpg) ### Lodge Of Four Seasons Golf Resort, Marina & Spa 10/10 Excellent "Great place go all the time" [](https://expedia.ca/Osage-Beach-Hotels-Lodge-Of-Four-Seasons-Golf-Resort.h40728.Hotel-Information) ![Inn at Grand Glaize](//images.trvl-media.com/lodging/1000000/70000/60700/60685/a0b4c124_y.jpg) ### Inn at Grand Glaize 10/10 Excellent "We always stay here when we are in town. This year it was packed due to shootout. We had reserved a dock and ours was takin at the end of the night. The mananagment was very accommodating. They have always been very nice. There door greater there is so great with people." [](https://expedia.ca/Osage-Beach-Hotels-Inn-At-Grand-Glaize.h60685.Hotel-Information) ![Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG](//images.trvl-media.com/lodging/8000000/7680000/7678000/7677926/8a05cd33_y.jpg) ### Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG 10/10 Excellent "Excellent stay. Friendly staff, and comfortable beds. " [](https://expedia.ca/Columbia-Hotels-Holiday-Inn-Express-Hotel-Suites-Columbia-Univ-Area-Hwy-63.h7677926.Hotel-Information) ![Hampton Inn Columbia](//images.trvl-media.com/lodging/1000000/50000/42100/42094/a2d2d168_y.jpg) ### Hampton Inn Columbia 10/10 Excellent "Renovations was going on but it was a nice stay. " [](https://expedia.ca/Columbia-Hotels-Hampton-Inn-Columbia.h42094.Hotel-Information) ![Margaritaville Lake Resort Lake of the Ozarks](//images.trvl-media.com/lodging/1000000/30000/21300/21228/268207dd_y.jpg) ### Margaritaville Lake Resort Lake of the Ozarks 10/10 Excellent "It was a great stay Hotel still needs some upgrades! Bed was squeaky! But overall we had a great time! I would recommend taco nachos at land shark bar they were very good! Souvenirs were way overpriced!" 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