Photo by Amber Palmer

Find hotels near Mayo Clinic Florida, Jacksonville from CA $68

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Filter by

Popular filters
Popular filters
Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Area
Area
Popular locations
1
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility
Traveller experience
Traveller experience

Top Hotels Close to Mayo Clinic Florida

Wyndham Garden Jacksonville
Memory foam beds, in-room safe, individually furnished, desk
Wyndham Garden Jacksonville
3.0 star property
7.0 out of 10, Good, 1,450 reviews
"Overall is good stay, the door to back parking lot was broken, it takes little walk to access. "
The price is CA $102
CA $116 total
includes taxes & fees
Jun 6 - Jun 7
Wyndham Garden Jacksonville
Embassy Suites by Hilton Jacksonville Baymeadows
Lobby
Embassy Suites by Hilton Jacksonville Baymeadows
3.5 star property
8.2 out of 10, Very good, 1,002 reviews
"I Love Embassy. Staff is really nice. Love evening reception. Wonderful breakfast. I didn’t give all stars, bathroom sink smells. Vinegar and baking soda would refresh it. Dusting the wood under the sink would be helpful. Light around the mirror going out(minor issue). Refrigerator not getting that cool. All minor stuff. I would definitely stay there again"
The price is CA $153
CA $174 total
includes taxes & fees
Jul 1 - Jul 2
Embassy Suites by Hilton Jacksonville Baymeadows
Best Western Oceanfront
On the beach
Best Western Oceanfront
3.0 star property
8.8 out of 10, Excellent, 1,005 reviews
"Very clean rooms, great staff"
The price is CA $193
CA $219 total
includes taxes & fees
Jun 30 - Jul 1
Best Western Oceanfront
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Four Points by Sheraton Jacksonville Beachfront
Exterior
Four Points by Sheraton Jacksonville Beachfront
3.0 star property
9.0 out of 10, Wonderful, 1,001 reviews
"Everything was nice and in order. The staff were friendly. "
The price is CA $283
CA $321 total
includes taxes & fees
Jun 5 - Jun 6
Four Points by Sheraton Jacksonville Beachfront
Holiday Inn Express Jacksonville Beach, an IHG Hotel
Standard Room, 2 Queen Beds, Accessible (Accessible Tub)
Holiday Inn Express Jacksonville Beach, an IHG Hotel
2.5 star property
9.0 out of 10, Wonderful, 1,003 reviews
"Good stay. A little expensive for the room. The staff was good. The young woman at front during the day was excellent"
The price is CA $194
CA $221 total
includes taxes & fees
Jun 23 - Jun 24
Holiday Inn Express Jacksonville Beach, an IHG Hotel
Residence Inn by Marriott Jacksonville Butler Boulevard
Outdoor pool
Residence Inn by Marriott Jacksonville Butler Boulevard
3.0 star property
8.8 out of 10, Excellent, 758 reviews
"The room is very big and has everything that you will need. Breakfast was excellent you can find some options. The location is amazing you are close to everywhere there. "
The price is CA $169
CA $192 total
includes taxes & fees
Jun 28 - Jun 29
Residence Inn by Marriott Jacksonville Butler Boulevard
Quality Inn Atlantic Beach - Mayo Clinic Jax Area
Standard Room, 2 Double Beds, Non Smoking
Quality Inn Atlantic Beach - Mayo Clinic Jax Area
2.5 star property
7.8 out of 10, Good, 1,005 reviews
"The room was clean and decent for the price we paid."
The price is CA $117
CA $133 total
includes taxes & fees
Jul 1 - Jul 2
Quality Inn Atlantic Beach - Mayo Clinic Jax Area
Hotel Indigo Jacksonville-Deerwood Park, an IHG Hotel
Exterior
Hotel Indigo Jacksonville-Deerwood Park, an IHG Hotel
3.5 star property
9.2 out of 10, Wonderful, 1,001 reviews
"We enjoyed our stay .the property was clean.room was clean. Could use new towels.also a micowave would be good in the room. Better lighting around mirror in bathroom. The employees were very friendly and tried to help as much as they could.it seemed they were short staffed. We had payed extra for breakfast everyday the restaurant ended up being closed due to unforseen circumstances. We spoke to someone at the desk.we were assured we would be reimbursed for the two days we didn't have...
The price is CA $174
CA $197 total
includes taxes & fees
Jun 16 - Jun 17
Hotel Indigo Jacksonville-Deerwood Park, an IHG Hotel
WoodSpring Suites Jacksonville - South
Exterior
WoodSpring Suites Jacksonville - South
2.5 star property
7.4 out of 10, Good, 297 reviews
"Stay was wonderful. Peaceful also"
The price is CA $96
CA $109 total
includes taxes & fees
Jun 3 - Jun 4
WoodSpring Suites Jacksonville - South
Courtyard by Marriott Jacksonville Butler Boulevard
Terrace/patio
Courtyard by Marriott Jacksonville Butler Boulevard
3.0 star property
8.8 out of 10, Excellent, 535 reviews
"We enjoyed our stay at Marriot and I think it could have been so much better if a microwave is provided in the room."
The price is CA $159
CA $180 total
includes taxes & fees
Jun 16 - Jun 17
Courtyard by Marriott Jacksonville Butler Boulevard
Hampton Inn & Suites Jacksonville Deerwood Park
Studio, 2 Queen Beds, Accessible, Non Smoking | Living area
Hampton Inn & Suites Jacksonville Deerwood Park
2.5 star property
9.2 out of 10, Wonderful, 1,002 reviews
"Always great!"
The price is CA $141
CA $160 total
includes taxes & fees
Jun 16 - Jun 17
Hampton Inn & Suites Jacksonville Deerwood Park
Tru by Hilton Jacksonville South Mandarin
Reception
Tru by Hilton Jacksonville South Mandarin
2.5 star property
8.8 out of 10, Excellent, 675 reviews
"Best place to stay and has good location in the area and only 20min of the downtown area. Thanks for everything and very good breakfast. You guys rock"
The price is CA $115
CA $131 total
includes taxes & fees
Jun 30 - Jul 1
Tru by Hilton Jacksonville South Mandarin
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Outdoor banquet area
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
9.4 out of 10, Exceptional, 268 reviews
"Y"
The price is CA $218
CA $247 total
includes taxes & fees
Jun 16 - Jun 17
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Courtyard by Marriott Jacksonville Flagler Center
Property amenity
Courtyard by Marriott Jacksonville Flagler Center
3.0 star property
8.8 out of 10, Excellent, 919 reviews
"Great stay and staff. Would stay again. "
The price is CA $127
CA $144 total
includes taxes & fees
Jun 16 - Jun 17
Courtyard by Marriott Jacksonville Flagler Center
Comfort Suites Baymeadows Near Butler Blvd
Exterior
Comfort Suites Baymeadows Near Butler Blvd
2.5 star property
7.8 out of 10, Good, 869 reviews
"Excellent hotel! Great price !"
The price is CA $127
CA $144 total
includes taxes & fees
Jun 16 - Jun 17
Comfort Suites Baymeadows Near Butler Blvd
Hampton Inn & Suites Jacksonville South - Bartram Park
Outdoor pool, sun loungers
Hampton Inn & Suites Jacksonville South - Bartram Park
3.0 star property
9.0 out of 10, Wonderful, 1,003 reviews
"It was a good stay. "
The price is CA $133
CA $151 total
includes taxes & fees
Jun 30 - Jul 1
Hampton Inn & Suites Jacksonville South - Bartram Park
Quality Inn & Suites Jacksonville-Baymeadows
Exterior
Quality Inn & Suites Jacksonville-Baymeadows
2.5 star property
5.6 out of 10, 1,001 reviews
"Good place but has room to become a Great place "
The price is CA $68
CA $79 total
includes taxes & fees
Jun 23 - Jun 24
Quality Inn & Suites Jacksonville-Baymeadows
Hampton Inn Jacksonville-I-295 East/Baymeadows
Lobby
Hampton Inn Jacksonville-I-295 East/Baymeadows
2.5 star property
8.8 out of 10, Excellent, 1,000 reviews
"Amazing, such kind staff! "
The price is CA $132
CA $150 total
includes taxes & fees
Jun 27 - Jun 28
Hampton Inn Jacksonville-I-295 East/Baymeadows
Tru By Hilton Jacksonville St Johns Town Center
Breakfast area
Tru By Hilton Jacksonville St Johns Town Center
2.5 star property
9.2 out of 10, Wonderful, 594 reviews
"Love the convenience of everything nearby. Wish there was a pool. "
The price is CA $169
CA $192 total
includes taxes & fees
Jun 9 - Jun 10
Tru By Hilton Jacksonville St Johns Town Center
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
Terrace/patio
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
8.4 out of 10, Very good, 642 reviews
"NICE PROPERTY "
The price is CA $220
CA $250 total
includes taxes & fees
Jun 8 - Jun 9
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
Don't see what you're looking for?
See all available properties in Mayo Clinic Florida
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels near Other Jacksonville Attractions

Image for Adventure Landing

Adventure Landing

4/5(1 review)

This amusement park east of Jacksonville is a fun daytrip for the whole family with thrilling rides, exciting attractions for kids and a shipwreck-themed waterpark.

See properties
Adventure Landing

Frequently asked questions

What's the area like around Mayo Clinic Florida?

Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, check out the 23 hotels and other accommodations you'll find within a mile.

What's the best place to stay close to Mayo Clinic Florida?

Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Another good choice is Residence Inn By Marriott Jacksonville - Mayo Clinic Area, located just 0.7 mi (1.1 km) away.

How many hotels will I find near Mayo Clinic Florida?

Expedia has 23 hotels and other accommodations within a mile from Mayo Clinic Florida.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?

Yes, you'll find most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best deals available near Mayo Clinic Florida.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Florida?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Florida, head over to our customer service page.

What can I see and do near Mayo Clinic Florida?

You can enjoy live performances at Players by the Sea and Wilson Center For the Arts. Spend some time exploring the natural beauty of Huguenot Park, Oceanfront Park, and Cradle Creek Preserve. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.

Recent Reviews in Mayo Clinic Florida
Expedia verified reviews

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

5/5 Excellent
"Great place"
A verified traveller stayed at Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Posted 17 hours ago
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area