Title: Book the Best Uptown SPA Resorts - Spa Hotels in Uptown, OH | Expedia.ca [Uptown Travel Guide](https://expedia.ca/Uptown.dx6059596)[Hotels in Uptown](https://expedia.ca/Uptown-Hotels.d6059596.Travel-Guide-Hotels)[Vacation Rentals in Uptown](https://expedia.ca/Uptown-Vacation-Rentals.d6059596.Travel-Guide-VacationRentals)[Flights to Uptown](https://expedia.ca/Cheap-Flights-To-Uptown.d6059596.Travel-Guide-Flights)[Things to do in Uptown](https://expedia.ca/Things-To-Do-In-Uptown.d6059596.Travel-Guide-Activities)[Uptown Car Rentals](https://expedia.ca/Car-Rentals-In-Uptown.d6059596.Car-Rental-Guide)[Uptown Vacation Packages](https://expedia.ca/Uptown.d6059596.Destination-Travel-Guides) ![Cincinnati Zoo and Botanical Garden featuring land animals and zoo animals](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/30000/30666-Cincinnati-Zoo-And-Botanical-Garden.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Uptown, OH ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Uptown Spa Hotels Tonight [Oct 2 - Oct 3](https://www.expedia.ca/Hotel-Search?regionId=6059596&startDate=2025-10-02&endDate=2025-10-03&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 3 - Oct 4](https://www.expedia.ca/Hotel-Search?regionId=6059596&startDate=2025-10-03&endDate=2025-10-04&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6059596&startDate=2025-10-03&endDate=2025-10-05&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6059596&startDate=2025-10-10&endDate=2025-10-12&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Uptown Spa Hotels ![Body treatments, hydrotherapy, hot stone massages, deep-tissue massages](https://images.trvl-media.com/lodging/6000000/5290000/5287100/5287002/7d7d2175.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5290000/5287100/5287002/5b64e900.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, Egyptian cotton sheets, premium bedding, in-room safe](https://images.trvl-media.com/lodging/6000000/5290000/5287100/5287002/e40ec4ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/6000000/5290000/5287100/5287002/083528eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 21c Museum Hotel Cincinnati Downtown Cincinnati 8.8/10 Excellent (1016) "would stay again" CA $250 CA $305 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Cincinnati-Hotels-21c-Museum-Hotel-Cincinnati.h5287002.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-16&endDate=2025-10-17®ionId=6059596&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Uptown Hotel Reviews ![Holiday Inn Cincinnati Airport by IHG](//images.trvl-media.com/lodging/1000000/30000/21100/21032/543a7af4_y.jpg) ### Holiday Inn Cincinnati Airport by IHG 10/10 Excellent "Clean and staff friendly and helpful. " [](https://expedia.ca/Covington-Hotels-Holiday-Inn-Cincinnati-Airport.h21032.Hotel-Information) ![Radisson Hotel Cincinnati Riverfront](//images.trvl-media.com/lodging/1000000/10000/2800/2755/68cff2fd_y.jpg) ### Radisson Hotel Cincinnati Riverfront 10/10 Excellent "Ladies at the front desk were amazing. " [](https://expedia.ca/Cincinnati-Hotels-Radisson-Hotel-Cincinnati-Riverfront.h2755.Hotel-Information) ![The Westin Cincinnati](//images.trvl-media.com/lodging/1000000/10000/3000/2972/62dde63a_y.jpg) ### The Westin Cincinnati 10/10 Excellent "Great location " [](https://expedia.ca/Cincinnati-Hotels-The-Westin-Cincinnati.h2972.Hotel-Information) ![Hilton Cincinnati Netherland Plaza](//images.trvl-media.com/lodging/1000000/10000/5900/5818/3a03c8ac_y.jpg) ### Hilton Cincinnati Netherland Plaza 10/10 Excellent "Great stay for a location within walking distance of all pro sporting stadiums and 1 arena " [](https://expedia.ca/Cincinnati-Hotels-Hilton-Cincinnati-Netherland-Plaza.h5818.Hotel-Information) ![Renaissance Cincinnati Downtown Hotel](//images.trvl-media.com/lodging/8000000/7320000/7316500/7316480/8f1dcd04_y.jpg) ### Renaissance Cincinnati Downtown Hotel 10/10 Excellent "I appreciated that location and easy access to the facility. The valet parking option was a wonderful option and appreciation the 24 hours service. The hotel staff was helpful and welcoming." [](https://expedia.ca/Cincinnati-Hotels-Renaissance-Cincinnati-Downtown-Hotel.h7316480.Hotel-Information) ![Hyatt Regency Cincinnati](//images.trvl-media.com/lodging/1000000/20000/18700/18646/1ec5d305_y.jpg) ### Hyatt Regency Cincinnati 10/10 Excellent "Loved the pool" [](https://expedia.ca/Cincinnati-Hotels-Hyatt-Regency-Cincinnati.h18646.Hotel-Information) ![Sonesta ES Suites Cincinnati - Blue Ash](//images.trvl-media.com/lodging/1000000/20000/16700/16690/8e04157a_y.jpg) ### Sonesta ES Suites Cincinnati - Blue Ash 10/10 Excellent "Staff was lovely, grounds were quiet and well-kept, and the room was comfortable / cozy" [](https://expedia.ca/Cincinnati-Hotels-Sonesta-ES-Suites-Cincinnati-Blue-Ash.h16690.Hotel-Information) ![Sonesta ES Suites Cincinnati - Sharonville East](//images.trvl-media.com/lodging/1000000/10000/5800/5786/41575616_y.jpg) ### Sonesta ES Suites Cincinnati - Sharonville East 10/10 Excellent "Clean room, nice staff and affordable. 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