Santee Vacation Rentals

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Vacation Rentals in Santee

Wyndham Vacation Resorts Lake Marion

4.0 star property
9.2 out of 10, Wonderful, (19)
"Friendly staff. Excellent accomodations. Peaceful and beautiful vacation."
Wyndham Vacation Resorts Lake Marion

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

10.0 out of 10, Exceptional, (34)
"We needed a place with two separate bedrooms. This property fit the bill. Perfect for our trip. Nice accommodations. Would definitely recommend this property. "
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Charming 2 Bedroom Waterfront Lake Marion Condo

10.0 out of 10, Exceptional, (2)
"We enjoyed your beautiful home. We visited with family. My daughter caught a nice catfish off the pier . We will be back one day. "
Charming 2 Bedroom Waterfront Lake Marion Condo

Private Dock + Pool Table: Lake Marion Getaway

9.0 out of 10, Wonderful, (2)
"Great property, we will return and highly recommended."
Private Dock + Pool Table: Lake Marion Getaway

Lake Side Condo Getaway

8.4 out of 10, Very good, (8)
"Property was as advertised. Very clean and the view was great. Pool and recreation area was a big bonus. "
Lake Side Condo Getaway

Lakeside Charming 2-bedroom house in lovely Santee with AC, WiFi

Lakeside Charming 2-bedroom house in lovely Santee with AC, WiFi

Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

10.0 out of 10, Exceptional, (8)
"Nice place great location "
Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

Lakeside vacationing close to golf courses, restaurants and boat rental company!

9.6 out of 10, Exceptional, (8)
"I had a very nice time and I will definitely come back here"
Lakeside vacationing close to golf courses, restaurants and boat rental company!

Elloree Vacation Rental ~ 7 Mi to Lake Marion!

3.0 star property
Elloree Vacation Rental ~ 7 Mi to Lake Marion!

Bells Marina & Resort

2.5 star property
8.6 out of 10, Excellent, (73)
"Had a great stay"
The price is CA $120
CA $133 total
includes taxes & fees
Aug 10 - Aug 11
Bells Marina & Resort

Pet friendly country cottage with large fenced-in yard & horses on property

10.0 out of 10, Exceptional, (105)
"Absolutely wonderful! We stayed overnight after a concert in Charleston with our high school age daughter and her friend. They couldn’t get over how “cute and aesthetic” the cottage was! We all loved the pet and family friendly property, the horses outside, and the many small touches inside that made us feel right at home! We will definitely look at staying here again!"
The price is CA $155
CA $282 total
includes taxes & fees
Aug 5 - Aug 6
Pet friendly country cottage with large fenced-in yard & horses on property

SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

9.8 out of 10, Exceptional, (237)
"It is our 4th time there and It was absolutely perfect! "
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

Country Resting Spot just off I95. 12 miles west on hwy 6.

9.0 out of 10, Wonderful, (14)
"Perfect spot to stay for a golf trip. Place was clean. Host was attentive and easy to work with. Thank you! We’ll be back!"
The price is CA $143
CA $208 total
includes taxes & fees
Aug 5 - Aug 6
Country Resting Spot just off I95. 12 miles west on hwy 6.

Lake Marion Lakehouse with 180° lake view

10.0 out of 10, Exceptional, (67)
"I would stay here again. Great location."
Lake Marion Lakehouse with 180° lake view

Beautiful lake home to make your family vacation extra special!

9.0 out of 10, Wonderful, (56)
"This was an awesome stay! Home was clean and comfortable. Great hosts!"
Beautiful lake home to make your family vacation extra special!

Lake Marion Home: Kayaks, Dock, Waterfront Fun!

9.4 out of 10, Exceptional, (8)
"This property was a very nice getaway for my friend and I. We enjoyed the quite neighborhood and sitting on the back porch enjoying the early fall weather. Hope to stay again in the future. "
Lake Marion Home: Kayaks, Dock, Waterfront Fun!

Sweet Marion - Dock + Boat Ramp + Hot Tub!

8.8 out of 10, Excellent, (14)
"Group of us older guys went for a golf weekend at Santee. The house was great and we really enjoyed our stay."
Sweet Marion - Dock + Boat Ramp + Hot Tub!

Archie's Lake Daze Cottage

10.0 out of 10, Exceptional, (73)
"We had a great time. Clean and everything we needed and then some!! We will definitely be back"
Archie's Lake Daze Cottage

Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy

9.8 out of 10, Exceptional, (87)
"The house was great. Would recommend to everyone. "
Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy

6 Bedrm, 4 full bath + 2 half bath Lake Marion Waterfront Home with 2025 updates

7.2 out of 10, Good, (11)
"Wonderful place to stay with a group. Rustic but has everything you need. Very comfortable. "
6 Bedrm, 4 full bath + 2 half bath Lake Marion Waterfront Home with 2025 updates
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santee Hotel Reviews

Frequently asked questions

Can I find vacation rentals in Santee?

Yes, we offer vacation rentals near the most popular points of interest in Santee, or you can select a more remote option if you'd like a relaxing place to stay. Tourists appreciate the top-notch restaurants and coffeehouses in Santee. Make sure you have time to check out the golf courses and lake views during your trip.

What are some of the best vacation home rentals in Santee?

Wyndham Vacation Resorts Lake Marion: This highly rated vacation home rental in Santee is equipped with an outdoor pool, free WiFi, and a TV to help you feel comfortable during your stay. It has 3 bedrooms as well as a kitchen with a full-sized fridge, a dishwasher, and a stovetop, so you can cook with friends or family. Other favorite homes for rent in Santee are Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95! and Private Dock + Pool Table: Lake Marion Getaway.

How many vacation rentals are there in Santee?

Expedia has 9 vacation rentals for your stay in Santee.

What can I see and do in Santee?

While you're exploring the area, Lake Marion and Taw Caw Creek are a couple of picturesque spots to get outside and enjoy nature. Santee Cooper Country Club and Santee National Golf Club are other places to visit while you're in town.

What are vacation rentals like in Santee?

Vacation rentals are private accommodations you can book for several days or more in Santee. Vacation rentals feature amenities like kitchens and laundry facilities so you'll feel just like you're at home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of safety away from public hotel elevators and bustling concierge desks while still allowing you the experience of travel. You'll also get more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a great choice for family gatherings.