Santee Vacation Rentals

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Our top choices for Santee vacation rentals

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Santee
10.0 out of 10, Exceptional, (39 reviews)
"Host was great. Place was nice and clean. We will book again. "
United States
Belford S.
The price is CA $117
CA $424 total
includes taxes & fees
Mar 4 - Mar 5
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!
Santee
10.0 out of 10, Exceptional, (11 reviews)
"Annual golf trip with old friends. Perfect accommodations & location. Hope to stay again"
United States
Greg M.
The price is CA $321
CA $709 total
includes taxes & fees
Mar 6 - Mar 7
Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks

LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks
Santee
The price is CA $257
CA $671 total
includes taxes & fees
Mar 5 - Mar 6
LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks

Country living lake style near Santee

Country living lake style near Santee
Summerton
10.0 out of 10, Exceptional, (42 reviews)
"Great stay."
United States
Tim E.
The price is CA $130
CA $293 total
includes taxes & fees
Mar 1 - Mar 2
Country living lake style near Santee

Country Resting Spot just off I95. 12 miles west on hwy 6.

Country Resting Spot just off I95. 12 miles west on hwy 6.
Elloree
9.4 out of 10, Exceptional, (22 reviews)
"Enjoyed the stay. Out in the country, Great!"
United States
Marty D.
The price is CA $148
CA $228 total
includes taxes & fees
Mar 15 - Mar 16
Country Resting Spot just off I95. 12 miles west on hwy 6.

Hobbs Haven at Lake Marion

Hobbs Haven at Lake Marion
Summerton
9.4 out of 10, Exceptional, (12 reviews)
"Great opportunity for family time!"
United States
faye c.
The price is CA $157
CA $484 total
includes taxes & fees
Mar 2 - Mar 3
Hobbs Haven at Lake Marion

Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6

Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6
Summerton
9.2 out of 10, Wonderful, (22 reviews)
"Great stay!! "
United States
Josh L.
The price is CA $121
CA $240 total
includes taxes & fees
Mar 1 - Mar 2
Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6

Cabin at the lake in Rimini, SC

Cabin at the lake in Rimini, SC
Rimini
7.8 out of 10, Good, (7 reviews)
"Great view, excellent communication with the owners, relaxing, peaceful. "
United States
Christie
The price is CA $116
CA $194 total
includes taxes & fees
Mar 2 - Mar 3
Cabin at the lake in Rimini, SC

Pet friendly country cottage with large fenced-in yard & horses on property

Pet friendly country cottage with large fenced-in yard & horses on property
Holly Hill
10.0 out of 10, Exceptional, (138 reviews)
"Great stay! The host was very polite and communicative."
United States
Anthony T.
The price is CA $171
CA $299 total
includes taxes & fees
Mar 30 - Mar 31
Pet friendly country cottage with large fenced-in yard & horses on property

Cozy Camping Cabin on Lake Marion near Congaree Nat Park

Cozy Camping Cabin on Lake Marion near Congaree Nat Park
Rimini
8.2 out of 10, Very good, (14 reviews)
"We enjoyed our stay. The only negative would be the fishing pier is no longer useable. "
United States
Derrick W.
The price is CA $105
CA $181 total
includes taxes & fees
Feb 28 - Mar 1
Cozy Camping Cabin on Lake Marion near Congaree Nat Park

Charming 2-bedroom townhome with AC and WiFi in peaceful Summerton

Charming 2-bedroom townhome with AC and WiFi in peaceful Summerton
Summerton
The price is CA $159
CA $374 total
includes taxes & fees
Mar 8 - Mar 9
Charming 2-bedroom townhome with AC and WiFi in peaceful Summerton

Bells Marina & Resort

Bells Marina & Resort
2.5 star property
Eutawville
8.6 out of 10, Excellent, (90 reviews)
"Super quaint, quiet, nice little get away."
United States
Karen
Bells Marina & Resort

Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston

Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston
Holly Hill
10.0 out of 10, Exceptional, (7 reviews)
"Great stay!"
United States
Hayden S.
The price is CA $171
CA $220 total
includes taxes & fees
Mar 6 - Mar 7
Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston

Modern apartment overlooking historic downtown Elloree, SC.

Modern apartment overlooking historic downtown Elloree, SC.
Elloree
The price is CA $101
CA $181 total
includes taxes & fees
Mar 6 - Mar 7
Modern apartment overlooking historic downtown Elloree, SC.

Turtle Cove - Lake Living on Lake Marion

Turtle Cove - Lake Living on Lake Marion
Summerton
The price is CA $171
CA $586 total
includes taxes & fees
Mar 1 - Mar 2
Turtle Cove - Lake Living on Lake Marion

Boat House (private Cabin) - Boat House (Private Cabin)

Boat House (private Cabin) - Boat House (Private Cabin)
Eutawville
10.0 out of 10, Exceptional, (1 review)
"This was a 1-night stop over for us, on the way to Florida. Unfortunately, we only had saltwater poles, or we would have loved to try our luck at fishing the lake. Fish were popping the water everywhere. We really enjoyed watching the gators cruising the lake as well! 1st for us. This was just a simple, no frills campground, but would love to ho back one day. Lodge was clean, and enjoyed sitting on the quiet back deck."
United States
Jaime W.
Boat House (private Cabin) - Boat House (Private Cabin)

Private Farm Stay on 30-Acres

Private Farm Stay on 30-Acres
Summerton
The price is CA $241
CA $615 total
includes taxes & fees
Mar 5 - Mar 6
Private Farm Stay on 30-Acres

Blue Bird Manor 3-bedroom house located in the heart of Orangeburg

Blue Bird Manor 3-bedroom house located in the heart of Orangeburg
Orangeburg
10.0 out of 10, Exceptional, (1 review)
"Absolutely loved it such an adorable home a host had a a quick response as well as tips! Very happy with our stay"
United States
jessie j.
The price is CA $207
CA $300 total
includes taxes & fees
Feb 28 - Mar 1
Blue Bird Manor 3-bedroom house located in the heart of Orangeburg

Sweet Marion - Dock + Boat Ramp + Hot Tub!

Sweet Marion - Dock + Boat Ramp + Hot Tub!
Summerton
8.6 out of 10, Excellent, (19 reviews)
"Nice comfortable place to stay"
United States
Dylan H.
The price is CA $200
CA $681 total
includes taxes & fees
Mar 8 - Mar 9
Sweet Marion - Dock + Boat Ramp + Hot Tub!

The Tee Vee Cove is the place to be located near great golfing, fishing and food

The Tee Vee Cove is the place to be located near great golfing, fishing and food
Elloree
The price is CA $185
CA $355 total
includes taxes & fees
Mar 30 - Mar 31
The Tee Vee Cove is the place to be located near great golfing, fishing and food
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top Santee Hotel Reviews

Find out more about Santee

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Santee. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find vacation rentals in Santee?

Yes, we offer vacation rentals near the most popular points of interest in Santee, or you can select a more remote option if you'd like a relaxing place to stay. Tourists appreciate the top-notch restaurants and coffeehouses in Santee. Make sure you have time to check out the golf courses and lake views during your trip.

What are some of the best vacation home rentals in Santee?

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!: This highly rated vacation home rental in Santee is located on a lake and has a patio, a selection of games, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family.

How many vacation rentals are there in Santee?

Expedia has 7 vacation rentals for your stay in Santee.

What can I see and do in Santee?

While you're exploring the area, Lake Marion and Santee National Wildlife Refuge are a couple of picturesque spots to get outside and enjoy nature. Santee Cooper Country Club and Santee National Golf Club are other places to visit while you're in town.

What are vacation rentals like in Santee?

Vacation rentals are private accommodations you can book for several days or more in Santee. Vacation rentals feature amenities like kitchens and laundry facilities so you'll feel just like you're at home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of safety away from public hotel elevators and bustling concierge desks while still allowing you the experience of travel. You'll also get more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a great choice for family gatherings.