Santee Vacation Rentals

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Vacation Rentals in Santee

View from property
Waterfront 3 Bedroom / 3 Bath Condo w/ Boat Slip Available
10.0 out of 10, Exceptional, (32)
"We had a great vacation here and Jerry was easily available for any questions we had. This unit had everything we needed for our stay. Great place to stay for family to enjoy time together and go fishing as well."
Waterfront 3 Bedroom / 3 Bath Condo w/ Boat Slip Available
Outdoor pool
Executive 2 BR/2 BA Lakefront Corner Suite Condo
9.2 out of 10, Wonderful, (20)
"In town for Birdfest weekend and really enjoyed our stay in the condo and area!"
Executive 2 BR/2 BA Lakefront Corner Suite Condo
Property grounds
Two Palms Lakehouse in Santee Just minutes from I95
7.6 out of 10, Good, (8)
"Great place for a couple days. We took advantage of the lake. Fishing was great for the grandchildren. I highly recommend this place if you enjoy being by the lake. Thank you."
Two Palms Lakehouse in Santee Just minutes from I95
Save an average of 15% on thousands of hotels when you're signed in
Aerial view
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
10.0 out of 10, Exceptional, (16)
"We just stayed for a night to recharge and hit the road again. It was the perfect place to rest for our family of 4 plus 2 dogs."
The price is CA $181
CA $500 total
includes taxes & fees
May 23 - May 24
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Outdoor pool
Wyndham Vacation Resorts Lake Marion
4.0 star property
9.4 out of 10, Exceptional, (15)
"I enjoy my stay, customer service was exceptional. Will book again. "
Wyndham Vacation Resorts Lake Marion
Property grounds
Lakeview Condo close to Fishing, golfing, and hiking.
Lakeview Condo close to Fishing, golfing, and hiking.
Lake
Bells Marina & Resort
4.5 star property
8.8 out of 10, Excellent, (38)
"Everybody was very kind and helpful. "
The price is CA $126
CA $140 total
includes taxes & fees
Jun 5 - Jun 6
Bells Marina & Resort
On the beach, sun loungers
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable
9.8 out of 10, Exceptional, (208)
"Great place to stay for fishing."
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable
Exterior
Cozy Cottage Just a Block From a Boat Landing and a Beautiful Pristine Lake
9.4 out of 10, Exceptional, (13)
"We came down to play a 3 day golf tournament. This place was perfect for us to rest and relax after a long day of golf. Place was clean, nice & quiet. We hope to stay here again."
Cozy Cottage Just a Block From a Boat Landing and a Beautiful Pristine Lake
Property grounds
Tom Charles Goat Island Fishing Retreat
9.8 out of 10, Exceptional, (32)
"Went on a fishing weekend with my son and found this place to be absolutely perfect. Good location to meet fishing guides, golf courses around. Place is very clean, and clearly the owner takes pride in their place. Perfect relaxing view of the lake at the end of the day. Could not have found a better place for this kind of getaway."
Tom Charles Goat Island Fishing Retreat
TV, fireplace
Lakefront Summerton Getaway w/ Boat Dock + Pool!
8.0 out of 10, Very good, (4)
"Very nice place. Very clean. Relaxing. And enjoyable.. thanknyou you!!! Will definitely recommend!!"
Lakefront Summerton Getaway w/ Boat Dock + Pool!
Exterior
Cozy Camping Cabin on Lake Marion near Congaree Nat Park
8.8 out of 10, Excellent, (5)
"My dad and I have stayed at this property a couple times now. Always a pleasant stay. We come to fish the upper lake and having a boat ramp on site is a plus. Thank you Alice!"
The price is CA $116
CA $168 total
includes taxes & fees
May 23 - May 24
Cozy Camping Cabin on Lake Marion near Congaree Nat Park
Property grounds
The Bunkhouse at St Julien - Vintage Waterfront Lake House
9.8 out of 10, Exceptional, (6)
"I would have given 5 stars, but there was a used bar of soap in the shower that makes you think it wasn't clean. Also, how often are the blankets washed since you have to make the beds back before you leave. Why is there a host fee when guests have to clean everything or be charged an additional fee. I understand not leaving a mess and never would, but for what it costs to stay, with all fees, guest shouldn't feel like or think that the place hasnt been properly cleaned and sanitized between...
The Bunkhouse at St Julien - Vintage Waterfront Lake House
Smart TV
Come Relax in the Country
10.0 out of 10, Exceptional, (27)
"Clean, quiet, pet friendly. Was a nice overnight stay on a long trip. Limited food options in the area tho. Would stay again."
The price is CA $128
CA $210 total
includes taxes & fees
May 28 - May 29
Come Relax in the Country
Property grounds
Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy
9.6 out of 10, Exceptional, (63)
"A great stay at the big red house for our first family vacation at the lake. We grew up on this lake and always enjoy being there! House was very clean and had enough basic supplies that we didn’t *need* much! Thank you for sharing your home! -Harllee Family"
Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy
Outdoor dining
Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS
10.0 out of 10, Exceptional, (119)
"Our host was very helpful and statyed in touch with us through out our stay to answer questions we had about the house. We are talking about returning next year! We all had a very relaxing time!"
Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS
Fridge, microwave, oven, stovetop
Beautiful lake home to make your family vacation extra special!
9.0 out of 10, Wonderful, (40)
"Vary good place to stay as long as you have a boat to go out on the lake"
Beautiful lake home to make your family vacation extra special!
Exterior
NEW LISTING! SANITIZED Lake Marion Lakefront! Ramp, Sleeps 13, Wi-Fi Cable
9.8 out of 10, Exceptional, (155)
"Great location on lake. Good access to fishing and family boat rides. House very clean and private with fully gated property. Beds slept well and good cooking products to use. If only one negative is pantry storage for big family for a week there is none. Had to leave our storage bins under table for non perishable food but 2 refrigerators was nice touch. Beautiful and quiet location and neighbors seem very friendly. Thanks for the use of you home"
NEW LISTING! SANITIZED Lake Marion Lakefront! Ramp, Sleeps 13, Wi-Fi Cable
Property grounds
Cabin at the lake in Rimini, SC
10.0 out of 10, Exceptional, (2)
"Great view, excellent communication with the owners, relaxing, peaceful. "
The price is CA $116
CA $168 total
includes taxes & fees
May 23 - May 24
Cabin at the lake in Rimini, SC
Fridge, microwave, oven, stovetop
Beautiful Lake Marion Views!! Pet Friendly! Newly renovated and updated!!
9.4 out of 10, Exceptional, (19)
"Great people"
Beautiful Lake Marion Views!! Pet Friendly! Newly renovated and updated!!
Don't see what you're looking for?
See all available properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other types of properties in Santee you may be interested in

Room, 2 Queen Beds, Non Smoking
Baymont by Wyndham Santee
2.5 star property
7.8 out of 10, Good, (1312)
"Very friendly employees. Room had everything we needed with a nice size refrigerator and a freezer! Which was great to refreeze our ice packs we needed. Nice continental breakfast. Price was reasonable also. Just needed one night to stay. King bed was comfortable. "
The price is CA $102
CA $113 total
includes taxes & fees
Jun 4 - Jun 5
Baymont by Wyndham Santee
Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing)
Tru By Hilton Santee
2.5 star property
9.0 out of 10, Wonderful, (112)
"Very clean Dogs allowed a big plus"
The price is CA $167
CA $186 total
includes taxes & fees
Jun 3 - Jun 4
Tru By Hilton Santee
Property amenity
Fairfield Inn & Suites by Marriott Santee
2.5 star property
9.8 out of 10, Exceptional, (994)
"Great "
The price is CA $193
CA $215 total
includes taxes & fees
May 28 - May 29
Fairfield Inn & Suites by Marriott Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Santee. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find vacation rentals in Santee?

Yes, we offer vacation rentals near the most popular points of interest in Santee, or you can select a more remote option if you'd like a relaxing place to stay. Tourists appreciate the top-notch restaurants and coffeehouses in Santee. Make sure you have time to check out the golf courses and lake views during your trip.

What are some of the best vacation home rentals in Santee?

SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable: This vacation home rental outside of Santee is located on the beach and has a fireplace, a patio, and a barbecue grill to put you at ease in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You can relax into your vacation with a garden and a selection of games.

How many vacation rentals are there in Santee?

Expedia has 7 vacation rentals for your stay in Santee.

What can I see and do in Santee?

Santee State Park and Lake Marion are a couple of lovely local spots to get outside and enjoy nature. Santee Cooper Country Club and Santee Outlets are other places to visit while you're in town.

What are vacation rentals like in Santee?

Vacation rentals are private accommodations you can book for several days or more in Santee. Vacation rentals feature amenities like kitchens and laundry facilities so you'll feel just like you're at home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of safety away from public hotel elevators and bustling concierge desks while still allowing you the experience of travel. You'll also get more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a great choice for family gatherings.

Recent reviews of Santee properties
Expedia verified reviews