Santee Vacation Rentals

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Our top choices for Santee vacation rentals

Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!
Santee
10.0 out of 10, Exceptional, (11 reviews)
"Annual golf trip with old friends. Perfect accommodations & location. Hope to stay again"
United States
Greg M.
The price is CA $317
CA $704 total
includes taxes & fees
May 13 - May 14
Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks

LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks
Santee
The price is CA $136
CA $523 total
includes taxes & fees
Apr 20 - Apr 21
LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Santee
10.0 out of 10, Exceptional, (42 reviews)
"This home was perfect for our Thanksgiving family getaway. We really enjoyed everything about the house, especially the fenced yard for the dogs. I would definitely stay here again. The house was exceptionally clean. "
United States
Kelly C.
The price is CA $114
CA $420 total
includes taxes & fees
Apr 16 - Apr 17
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Country living lake style near Santee

Country living lake style near Santee
Summerton
10.0 out of 10, Exceptional, (43 reviews)
"Great stay."
United States
Tim E.
The price is CA $130
CA $296 total
includes taxes & fees
Apr 29 - Apr 30
Country living lake style near Santee

Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301

Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301
Bowman
9.8 out of 10, Exceptional, (33 reviews)
"Will stay again."
United States
Robert B.
The price is CA $105
CA $223 total
includes taxes & fees
Apr 17 - Apr 18
Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301

Bells Marina & Resort

Bells Marina & Resort
2.5 star property
Eutawville
8.6 out of 10, Excellent, (93 reviews)
"Super quaint, quiet, nice little get away."
United States
Karen
The price is CA $146
CA $166 total
includes taxes & fees
Apr 19 - Apr 20
Bells Marina & Resort

SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable
Summerton
9.6 out of 10, Exceptional, (252 reviews)
"We had a great family retreat "
United States
Ernestine C.
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

Private Farm Stay on 30-Acres with Fish Pond + Sleeps 8

Private Farm Stay on 30-Acres with Fish Pond + Sleeps 8
Summerton
The price is CA $302
CA $732 total
includes taxes & fees
Apr 29 - Apr 30
Private Farm Stay on 30-Acres with Fish Pond + Sleeps 8

Beautiful brick home w/ large porch and 3 bedrooms

Beautiful brick home w/ large porch and 3 bedrooms
Bowman
9.2 out of 10, Wonderful, (5 reviews)
"Nice and quiet property. It served us well for the weekend "
United States
Mick S.
The price is CA $204
CA $387 total
includes taxes & fees
Apr 18 - Apr 19
Beautiful brick home w/ large porch and 3 bedrooms

Pet friendly country cottage with large fenced-in yard & horses on property

Pet friendly country cottage with large fenced-in yard & horses on property
Holly Hill
10.0 out of 10, Exceptional, (141 reviews)
"Our host was excellent and the fenced-in yard was perfect for our dog!"
United States
Michael H.
The price is CA $155
CA $281 total
includes taxes & fees
Apr 29 - Apr 30
Pet friendly country cottage with large fenced-in yard & horses on property

Turtle Cove - Lake Living on Lake Marion

Turtle Cove - Lake Living on Lake Marion
Summerton
The price is CA $172
CA $609 total
includes taxes & fees
Apr 26 - Apr 27
Turtle Cove - Lake Living on Lake Marion

Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston

Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston
Holly Hill
10.0 out of 10, Exceptional, (11 reviews)
"Great stay!"
United States
Hayden S.
The price is CA $172
CA $221 total
includes taxes & fees
Apr 29 - Apr 30
Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston

Cozy Camping Cabin on Lake Marion near Congaree Nat Park

Cozy Camping Cabin on Lake Marion near Congaree Nat Park
Rimini
8.4 out of 10, Very good, (15 reviews)
"We enjoyed our stay. The only negative would be the fishing pier is no longer useable. "
United States
Derrick W.
The price is CA $105
CA $182 total
includes taxes & fees
Apr 29 - Apr 30
Cozy Camping Cabin on Lake Marion near Congaree Nat Park

Boat House (private Cabin) - Boat House (Private Cabin)

Boat House (private Cabin) - Boat House (Private Cabin)
Eutawville
10.0 out of 10, Exceptional, (1 review)
"This was a 1-night stop over for us, on the way to Florida. Unfortunately, we only had saltwater poles, or we would have loved to try our luck at fishing the lake. Fish were popping the water everywhere. We really enjoyed watching the gators cruising the lake as well! 1st for us. This was just a simple, no frills campground, but would love to ho back one day. Lodge was clean, and enjoyed sitting on the quiet back deck."
United States
Jaime W.
The price is CA $289
CA $443 total
includes taxes & fees
May 10 - May 11
Boat House (private Cabin) - Boat House (Private Cabin)

The Beehive is 19 miles from I-95, 16 miles from I-26. Fishing, hunting & more.

The Beehive is 19 miles from I-95, 16 miles from I-26. Fishing, hunting & more.
Cross
10.0 out of 10, Exceptional, (1 review)
"The time at the sweet apartment was a relief for myself and my little one The utilities were nice and clean and we felt comfortable . Thank you so much."
United States
Lesley B.
The price is CA $191
CA $303 total
includes taxes & fees
Apr 29 - Apr 30
The Beehive is 19 miles from I-95, 16 miles from I-26. Fishing, hunting & more.

The Tee Vee Cove is the place to be located near great golfing, fishing and food

The Tee Vee Cove is the place to be located near great golfing, fishing and food
Elloree
8.0 out of 10, Very good, (1 review)
"Came to area for hiking. Plenty of spots and the location was great. Wonderful experience and enjoyed the outside patio in the evenings."
United States
Debra S.
The price is CA $198
CA $379 total
includes taxes & fees
Apr 18 - Apr 19
The Tee Vee Cove is the place to be located near great golfing, fishing and food

Modern apartment overlooking historic downtown Elloree, SC.

Modern apartment overlooking historic downtown Elloree, SC.
Elloree
The price is CA $158
CA $252 total
includes taxes & fees
Apr 18 - Apr 19
Modern apartment overlooking historic downtown Elloree, SC.

Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6

Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6
Summerton
9.0 out of 10, Wonderful, (25 reviews)
"Overall an excellent stay! "
United States
Andy K.
The price is CA $119
CA $238 total
includes taxes & fees
Apr 29 - Apr 30
Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6

Country Resting Spot just off I95. 12 miles west on hwy 6.

Country Resting Spot just off I95. 12 miles west on hwy 6.
Elloree
9.4 out of 10, Exceptional, (23 reviews)
"Enjoyed the stay. Out in the country, Great!"
United States
Marty D.
The price is CA $172
CA $255 total
includes taxes & fees
May 10 - May 11
Country Resting Spot just off I95. 12 miles west on hwy 6.

Reel Haven on the Water: Modern + Comfy Home!

Reel Haven on the Water: Modern + Comfy Home!
Eutawville
6.8 out of 10, (5 reviews)
"Perfect place for a weekend fishing trip. Owner was responsive. Slept 6 easily. Only stayed one night but was a perfect fit"
United States
brandon h.
The price is CA $192
CA $635 total
includes taxes & fees
Apr 20 - Apr 21
Reel Haven on the Water: Modern + Comfy Home!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santee Hotel Reviews

Find out more about Santee

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Santee. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find vacation rentals in Santee?

Yes, we offer vacation rentals near the most popular points of interest in Santee, or you can select a more remote option if you'd like a relaxing place to stay. Tourists appreciate the top-notch restaurants and coffeehouses in Santee. Make sure you have time to check out the golf courses and lake views during your trip.

What are some of the best vacation home rentals in Santee?

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!: This highly rated vacation home rental in Santee is located on a lake and has a patio, a selection of games, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family.

How many vacation rentals are there in Santee?

Expedia has 8 vacation rentals for your stay in Santee.

What can I see and do in Santee?

While you're exploring the area, Lake Marion and Taw Caw Creek are a couple of picturesque spots to get outside and enjoy nature. Santee Cooper Country Club and Santee National Golf Club are other places to visit while you're in town.

What are vacation rentals like in Santee?

Vacation rentals are private accommodations you can book for several days or more in Santee. Vacation rentals feature amenities like kitchens and laundry facilities so you'll feel just like you're at home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of safety away from public hotel elevators and bustling concierge desks while still allowing you the experience of travel. You'll also get more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a great choice for family gatherings.