Santee Vacation Rentals

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Our top choices for Santee vacation rentals

LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks

LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks
Santee
8.0 out of 10, Very good, (4 reviews)
"Great stay no complaints. "
United States
Quantrel P.
The price is CA $150
CA $540 total
includes taxes & fees
Jun 6 - Jun 7
LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Santee
10.0 out of 10, Exceptional, (43 reviews)
"Thanks again Mike for a great stay! All the best, Paul"
United States
Paul V.
The price is CA $197
CA $531 total
includes taxes & fees
Jun 8 - Jun 9
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!
Santee
10.0 out of 10, Exceptional, (14 reviews)
"Annual golf trip with old friends. Perfect accommodations & location. Hope to stay again"
United States
Greg M.
The price is CA $317
CA $709 total
includes taxes & fees
Jun 7 - Jun 8
Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

Country living lake style near Santee

Country living lake style near Santee
Summerton
10.0 out of 10, Exceptional, (46 reviews)
"Clean, private, well maintained. Adequate parking for boaters. Excellent location for lake bound vacationers. Host very responsive."
United States
Jeffrey
The price is CA $131
CA $297 total
includes taxes & fees
Jun 1 - Jun 2
Country living lake style near Santee

Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6

Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6
Summerton
8.6 out of 10, Excellent, (31 reviews)
"Lake view and location was great. Everyone in the park was very friendly. Good diner. Perfect for us!!!!!"
United States
Elizabeth
The price is CA $135
CA $257 total
includes taxes & fees
Jun 8 - Jun 9
Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6

Bells Marina & Resort

Bells Marina & Resort
2.5 star property
Eutawville
8.6 out of 10, Excellent, (93 reviews)
"Super quaint, quiet, nice little get away."
United States
Karen
The price is CA $147
CA $167 total
includes taxes & fees
Jun 2 - Jun 3
Bells Marina & Resort

Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301

Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301
Bowman
9.8 out of 10, Exceptional, (33 reviews)
"Will stay again."
United States
Robert B.
The price is CA $106
CA $224 total
includes taxes & fees
Jun 1 - Jun 2
Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301

Cozy Camping Cabin on Lake Marion near Congaree Nat Park

Cozy Camping Cabin on Lake Marion near Congaree Nat Park
Rimini
8.4 out of 10, Very good, (16 reviews)
"We enjoyed our stay. The only negative would be the fishing pier is no longer useable. "
United States
Derrick W.
The price is CA $106
CA $183 total
includes taxes & fees
Jun 1 - Jun 2
Cozy Camping Cabin on Lake Marion near Congaree Nat Park

Pet friendly country cottage with large fenced-in yard & horses on property

Pet friendly country cottage with large fenced-in yard & horses on property
Holly Hill
10.0 out of 10, Exceptional, (146 reviews)
"Nice place, friendly hosts!"
United States
Dan R.
The price is CA $155
CA $282 total
includes taxes & fees
Jun 2 - Jun 3
Pet friendly country cottage with large fenced-in yard & horses on property

Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston

Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston
Holly Hill
10.0 out of 10, Exceptional, (13 reviews)
"Great stay!"
United States
Hayden S.
The price is CA $172
CA $222 total
includes taxes & fees
Jun 4 - Jun 5
Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston

Modern apartment overlooking historic downtown Elloree, SC.

Modern apartment overlooking historic downtown Elloree, SC.
Elloree
The price is CA $159
CA $254 total
includes taxes & fees
Jun 1 - Jun 2
Modern apartment overlooking historic downtown Elloree, SC.

Cabin at the lake in Rimini, SC

Cabin at the lake in Rimini, SC
Rimini
7.8 out of 10, Good, (7 reviews)
"Great view, excellent communication with the owners, relaxing, peaceful. "
United States
Christie
The price is CA $117
CA $196 total
includes taxes & fees
Jun 2 - Jun 3
Cabin at the lake in Rimini, SC

Turtle Cove - Lake Living on Lake Marion

Turtle Cove - Lake Living on Lake Marion
Summerton
The price is CA $217
CA $669 total
includes taxes & fees
Jun 16 - Jun 17
Turtle Cove - Lake Living on Lake Marion

Private Farm Stay on 30-Acres with Fish Pond + Sleeps 8

Private Farm Stay on 30-Acres with Fish Pond + Sleeps 8
Summerton
The price is CA $303
CA $735 total
includes taxes & fees
Jun 1 - Jun 2
Private Farm Stay on 30-Acres with Fish Pond + Sleeps 8

The Tee Vee Cove is the place to be located near great golfing, fishing and food

The Tee Vee Cove is the place to be located near great golfing, fishing and food
Elloree
9.0 out of 10, Wonderful, (2 reviews)
"Came to area for hiking. Plenty of spots and the location was great. Wonderful experience and enjoyed the outside patio in the evenings."
United States
Debra S.
The price is CA $164
CA $340 total
includes taxes & fees
Jun 1 - Jun 2
The Tee Vee Cove is the place to be located near great golfing, fishing and food

Blue Bird Manor 3-bedroom house located in the heart of Orangeburg

Blue Bird Manor 3-bedroom house located in the heart of Orangeburg
Orangeburg
10.0 out of 10, Exceptional, (2 reviews)
"Absolutely loved it such an adorable home a host had a a quick response as well as tips! Very happy with our stay"
United States
jessie j.
The price is CA $211
CA $305 total
includes taxes & fees
Jun 1 - Jun 2
Blue Bird Manor 3-bedroom house located in the heart of Orangeburg

Beautiful brick home w/ large porch and 3 bedrooms

Beautiful brick home w/ large porch and 3 bedrooms
Bowman
9.2 out of 10, Wonderful, (5 reviews)
"A great home and very peaceful!! The host is very friendly and very easy to work with. I recommend this home for a stay 100 percent!!We plan on staying there again when we are in the area, such a great value!!"
United States
Troy K.
The price is CA $205
CA $390 total
includes taxes & fees
Jun 12 - Jun 13
Beautiful brick home w/ large porch and 3 bedrooms

Boat House (private Cabin) - Boat House (Private Cabin)

Boat House (private Cabin) - Boat House (Private Cabin)
Eutawville
10.0 out of 10, Exceptional, (1 review)
"This was a 1-night stop over for us, on the way to Florida. Unfortunately, we only had saltwater poles, or we would have loved to try our luck at fishing the lake. Fish were popping the water everywhere. We really enjoyed watching the gators cruising the lake as well! 1st for us. This was just a simple, no frills campground, but would love to ho back one day. Lodge was clean, and enjoyed sitting on the quiet back deck."
United States
Jaime W.
The price is CA $357
CA $527 total
includes taxes & fees
Jun 24 - Jun 25
Boat House (private Cabin) - Boat House (Private Cabin)

SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable
Summerton
9.6 out of 10, Exceptional, (255 reviews)
"We stayed here for a Valentine’s fisherman’s weekend on Lake Marion, and the outdoor space is truly special. The private dock, quaint sandy beach area, and large backyard make it perfect for fishing, relaxing, and enjoying the lake. It’s a great setup for families and anyone who loves authentic lake living. The home reflects a true rustic lake house experience, with updated stainless steel appliances, an excellent shower, and one of the most comfortable mattresses. Peaceful, spacious, and true...
United States
Parisia C.
The price is CA $483
CA $864 total
includes taxes & fees
Jun 30 - Jul 1
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santee Hotel Reviews

Find out more about Santee

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Santee. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find vacation rentals in Santee?

Yes, we offer vacation rentals near the most popular points of interest in Santee, or you can select a more remote option if you'd like a relaxing place to stay. Tourists appreciate the top-notch restaurants and coffeehouses in Santee. Make sure you have time to check out the golf courses and lake views during your trip.

What are some of the best vacation home rentals in Santee?

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!: Visitors like this Santee vacation home rental. It is located on a lake and has a patio, a selection of games, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Another good choice for your trip to Santee is Patio + Pool Table: Lake Marion Getaway.

How many vacation rentals are there in Santee?

Expedia has 8 vacation rentals for your stay in Santee.

What can I see and do in Santee?

While you're exploring the area, Lake Marion and Taw Caw Creek are a couple of picturesque spots to get outside and enjoy nature. Santee Cooper Country Club and Santee National Golf Club are other places to visit while you're in town.

What are vacation rentals like in Santee?

Vacation rentals are private accommodations you can book for several days or more in Santee. Vacation rentals feature amenities like kitchens and laundry facilities so you'll feel just like you're at home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of safety away from public hotel elevators and bustling concierge desks while still allowing you the experience of travel. You'll also get more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a great choice for family gatherings.