Santee River Dam on Lake Marion, South Carolina, Aerial drone view of electric power lines

Santee Vacation Rentals

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Our top choices for Santee vacation rentals

1. Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Santee
10.0 out of 10, Exceptional, (46 reviews)
"This was our first long trip with our dog and she loved the place! Fenced in yard and home was cozy and dog friendly. Loved the farmhouse style and large bedrooms and baths. "
United States
Lori B.
The price is CA $123
CA $434 total
includes taxes & fees
Sep 1 - Sep 2
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

2. LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks

LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks
Santee
8.8 out of 10, Excellent, (6 reviews)
"Great stay no complaints. "
United States
Quantrel P.
The price is CA $250
CA $665 total
includes taxes & fees
Sep 19 - Sep 20
LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks

3. Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!
Santee
10.0 out of 10, Exceptional, (15 reviews)
"This is an amazing place to stay! Wake up in a beautiful place with stunning views and huge kitchen! Multiple boat docks that you can see turtles, alligators, fish from! Highly recommend "
United States
Hope M.
The price is CA $222
CA $588 total
includes taxes & fees
Sep 20 - Sep 21
Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

4. Lake Marion Condo, Boat Slip Included, Pet Friendly

Lake Marion Condo, Boat Slip Included, Pet Friendly
Santee
The price is CA $229
CA $483 total
includes taxes & fees
Aug 31 - Sep 1
Lake Marion Condo, Boat Slip Included, Pet Friendly

5. Bells Marina & Resort

Bells Marina & Resort
2.5 star property
Eutawville
8.6 out of 10, Excellent, (98 reviews)
"If you’re looking for a quiet and peaceful getaway this place was great! The lake is beautiful and you can kayak or just sit out by the water and relax. The cute ducks in the property were my favorite. Would definitely go back again."
United States
Amber
The price is CA $96
CA $111 total
includes taxes & fees
Aug 31 - Sep 1
Bells Marina & Resort

6. Country living lake style near Santee

Country living lake style near Santee
Summerton
10.0 out of 10, Exceptional, (46 reviews)
"Very convenient to the lake."
United States
John P.
The price is CA $132
CA $295 total
includes taxes & fees
Sep 8 - Sep 9
Country living lake style near Santee

7. Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6

Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6
Summerton
8.8 out of 10, Excellent, (36 reviews)
"Great place to stay on the lake! "
United States
Troy S.
The price is CA $121
CA $242 total
includes taxes & fees
Sep 27 - Sep 28
Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6

8. The Tee Vee Cove is the place to be located near great golfing, fishing and food

The Tee Vee Cove is the place to be located near great golfing, fishing and food
Elloree
9.4 out of 10, Exceptional, (3 reviews)
"Came to area for hiking. Plenty of spots and the location was great. Wonderful experience and enjoyed the outside patio in the evenings."
United States
Debra S.
The Tee Vee Cove is the place to be located near great golfing, fishing and food

9. Private Farm Stay on 30-Acres with Fish Pond + Sleeps 8

Private Farm Stay on 30-Acres with Fish Pond + Sleeps 8
Summerton
10.0 out of 10, Exceptional, (1 review)
"A Perfect Family Getaway!Our stay at this beautiful Summerton cabin was everything we hoped for and more. It provided the perfect opportunity to step back into a simpler time, unplug, and truly focus on making memories together as a family.The host family is wonderful. We purchased some of their farm-fresh goodies ahead of time, and having them waiting for us at the cabin when we arrived was a fantastic touch. A major highlight of our trip was getting to see all of the farm animals and the farm...
United States
Max N.
The price is CA $306
CA $738 total
includes taxes & fees
Aug 31 - Sep 1
Private Farm Stay on 30-Acres with Fish Pond + Sleeps 8

10. Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301

Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301
Bowman
9.8 out of 10, Exceptional, (35 reviews)
"The place was excellent. The bed was really nice and comfortable. I'd definitely stay again."
United States
Joseph
The price is CA $106
CA $226 total
includes taxes & fees
Sep 1 - Sep 2
Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301

11. Pet friendly country cottage with large fenced-in yard & horses on property

Pet friendly country cottage with large fenced-in yard & horses on property
Holly Hill
10.0 out of 10, Exceptional, (157 reviews)
"Allow us and four girls aka dogs a nice stop on way to and from Florida peaceful nice fenced yard will be back next year"
United States
Catrina C.
The price is CA $174
CA $306 total
includes taxes & fees
Sep 21 - Sep 22
Pet friendly country cottage with large fenced-in yard & horses on property

12. Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston

Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston
Holly Hill
10.0 out of 10, Exceptional, (14 reviews)
"Great stay!"
United States
Hayden S.
The price is CA $174
CA $224 total
includes taxes & fees
Sep 2 - Sep 3
Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston

13. Beautiful brick home w/ large porch and 3 bedrooms

Beautiful brick home w/ large porch and 3 bedrooms
Bowman
9.2 out of 10, Wonderful, (5 reviews)
"A great home and very peaceful!! The host is very friendly and very easy to work with. I recommend this home for a stay 100 percent!!We plan on staying there again when we are in the area, such a great value!!"
United States
Troy K.
The price is CA $206
CA $391 total
includes taxes & fees
Aug 31 - Sep 1
Beautiful brick home w/ large porch and 3 bedrooms

14. Relax and unwind near Lake Marion - 2-bedroom 1.5 bath cabin getaway.

Relax and unwind near Lake Marion - 2-bedroom 1.5 bath cabin getaway.
Summerton
The price is CA $232
CA $431 total
includes taxes & fees
Aug 31 - Sep 1
Relax and unwind near Lake Marion - 2-bedroom 1.5 bath cabin getaway.

15. Modern apartment overlooking historic downtown Elloree, SC.

Modern apartment overlooking historic downtown Elloree, SC.
Elloree
The price is CA $174
CA $270 total
includes taxes & fees
Aug 31 - Sep 1
Modern apartment overlooking historic downtown Elloree, SC.

16. Quiet 1-bedroom apartment in charming Elloree, SC

Quiet 1-bedroom apartment in charming Elloree, SC
Elloree
The price is CA $156
CA $251 total
includes taxes & fees
Aug 31 - Sep 1
Quiet 1-bedroom apartment in charming Elloree, SC

17. Cozy Camping Cabin on Lake Marion near Congaree Nat Park

Cozy Camping Cabin on Lake Marion near Congaree Nat Park
Rimini
8.4 out of 10, Very good, (16 reviews)
"Great place to stay. "
United States
Scott J.
The price is CA $114
CA $193 total
includes taxes & fees
Aug 31 - Sep 1
Cozy Camping Cabin on Lake Marion near Congaree Nat Park

18. Country Resting Spot just off I95. 12 miles west on hwy 6.

Country Resting Spot just off I95. 12 miles west on hwy 6.
Elloree
9.4 out of 10, Exceptional, (23 reviews)
"Amazing "
United States
Fisher R.
The price is CA $174
CA $258 total
includes taxes & fees
Sep 2 - Sep 3
Country Resting Spot just off I95. 12 miles west on hwy 6.

19. Turtle Cove - Lake Living on Lake Marion

Turtle Cove - Lake Living on Lake Marion
Summerton
10.0 out of 10, Exceptional, (1 review)
"Great quiet and cozy home with a nice backyard and porch with the easy water access by dock. Really enjoyed our stay."
United States
Judith H.
The price is CA $173
CA $615 total
includes taxes & fees
Aug 31 - Sep 1
Turtle Cove - Lake Living on Lake Marion

20. Cabin at the lake in Rimini, SC

Cabin at the lake in Rimini, SC
Rimini
7.4 out of 10, Good, (8 reviews)
"Great view, excellent communication with the owners, relaxing, peaceful. "
United States
Christie
The price is CA $120
CA $200 total
includes taxes & fees
Aug 31 - Sep 1
Cabin at the lake in Rimini, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santee Hotel Reviews

Find out more about Santee

Everything you need to know about Santee vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santee vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santee vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Santee vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santee. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santee vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Santee vacation rentals we have selected for you start as low as CA $111 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Santee rentals

At Expedia, we put the best Santee vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Santee rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santee vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santee. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in Santee?

Yes, we offer vacation rentals near the most popular points of interest in Santee, or you can select a more remote option if you'd like a relaxing place to stay. Tourists appreciate the top-notch restaurants and coffeehouses in Santee. Make sure you have time to check out the golf courses and lake views during your trip.

What are some of the best vacation home rentals in Santee?

Patio + Pool Table: Lake Marion Getaway: Visitors like this Santee vacation home rental. It is located on a lake and has a patio, a garden, and air-conditioning to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. Another good choice for your trip to Santee is Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!.

How many vacation rentals are there in Santee?

Expedia has 7 vacation rentals for your stay in Santee.

What can I see and do in Santee?

While you're exploring the area, Lake Marion and Santee National Wildlife Refuge are a couple of picturesque spots to get outside and enjoy nature. Santee Cooper Country Club and Santee State Park are other places to visit while you're in town.

What are vacation rentals like in Santee?

Vacation rentals are private accommodations you can book for several days or more in Santee. Vacation rentals feature amenities like kitchens and laundry facilities so you'll feel just like you're at home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of safety away from public hotel elevators and bustling concierge desks while still allowing you the experience of travel. You'll also get more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a great choice for family gatherings.