Title: Visit Santo Spirito: Best of Santo Spirito, Florence Travel 2026 | Expedia Tourism - Expedia.ca [Hotels in Santo Spirito](https://expedia.ca/Santo-Spirito-Florence-Hotels.0-n553248633938935375-0.Travel-Guide-Filter-Hotels)[Flights to Florence](https://expedia.ca/Cheap-Flights-To-Florence.d1222.Travel-Guide-Flights)[Things to do in Florence](https://expedia.ca/Things-To-Do-In-Florence.d1222.Travel-Guide-Activities)[Santo Spirito Car Rentals](https://expedia.ca/Car-Rentals-In-Santo-Spirito.d553248633938935375.Car-Rental-Guide)[Santo Spirito Vacations](https://expedia.ca/Santo-Spirito.d553248633938935375.Destination-Travel-Guides) # Santo Spirito ## Florence ![Province of Florence showing interior views, heritage elements and a church or cathedral](https://images.trvl-media.com/place/179893/dd801080-5529-49c4-b78b-415c9c4a56e9.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Province of Florence showing interior views, heritage elements and a church or cathedral](https://images.trvl-media.com/place/179893/dd801080-5529-49c4-b78b-415c9c4a56e9.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Province of Florence which includes a bridge, night scenes and a river or creek](https://images.trvl-media.com/place/179893/d6593db1-37e9-4616-898c-2181d3165076.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Province of Florence featuring markets and street scenes](https://images.trvl-media.com/place/179893/153cb425-fe7e-4254-919e-7419f0c1b3bb.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Province of Florence featuring heritage architecture and a church or cathedral](https://images.trvl-media.com/place/179893/d0760611-8e61-4e13-8383-a634f807d693.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Santo Spirito Things to do Hotels Where to stay [Florence travel guide](https://expedia.ca/Florence.dx1222) --- ### Popular places to visit ![Florence, Italy - Basilica di Santo Spirito, Tuscany religious architecture](https://images.trvl-media.com/place/6265853/6f1a3d40-9736-49ac-bcc7-097069f7ff9b.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Piazza Santo Spirito Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and stunning cathedral in this vibrant area. [](https://expedia.ca/Piazza-Santo-Spirito-Florence.d6265853.Vacation-Attraction) ![Ancient Roman gate into the old city of Florence, Italy. Porta Romana or Porta San Pier Gattolino](https://images.trvl-media.com/place/501037/2773ddf7-7ad2-4b95-a43a-15f2a40703cd.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Porta Romana 3/5(2 reviews) Find out about the history of Arcetri when you take a trip to Porta Romana. Amble around this vibrant area's riverfront or experience its fascinating museums. [](https://expedia.ca/Porta-Romana-Florence.d501037.Vacation-Attraction) ![Brancacci Chapel which includes heritage architecture and a church or cathedral](https://images.trvl-media.com/place/6143202/ad4f7c9f-cf49-4c66-b85b-1564733b578e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Brancacci Chapel A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine. [](https://expedia.ca/Brancacci-Chapel-Florence.d6143202.Vacation-Attraction) #### Santo Spirito Basilica Learn about the local history of Florence when you spend time at Santo Spirito Basilica. Stroll along the riverfront or visit the churches in this vibrant area. [](https://expedia.ca/Santo-Spirito-Basilica-Florence.d6075452.Vacation-Attraction) #### Torrigiani Garden Explore the great outdoors at Torrigiani Garden, a lovely green space in Florence. Stroll along the riverfront or visit the stunning cathedral in this vibrant area. [](https://expedia.ca/Torrigiani-Garden-Florence.d553248621532498389.Vacation-Attraction) #### Santa Maria della Carmine You can learn about the history of Florence with a visit to Santa Maria della Carmine. Visit the notable monuments and stunning cathedral in this vibrant area. [](https://expedia.ca/Santa-Maria-Della-Carmine-Florence.d6075450.Vacation-Attraction) ### Things to do ![Florence Accademia Gallery Tour with Entrance Ticket Included](https://mediaim.expedia.com/localexpert/3066485/d26c5e31-1f44-4056-bdee-2fc35c6c6ffc.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Florence Accademia Gallery Tour with Entrance Ticket Included CA $61 per adult **92%** of travellers recommend [](https://expedia.ca/things-to-do/florence-accademia-gallery-tour-with-entrance-ticket-included.a3066485.activity-details) ![Tuscany Experience In Pisa, Siena, San Gimignano & Chianti](https://mediaim.expedia.com/localexpert/880286/269c0081-b51e-4e1d-ac21-b19cf125da10.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Tuscany Experience In Pisa, Siena, San Gimignano & Chianti CA $79 per adult **92%** of travellers recommend [](https://expedia.ca/things-to-do/tuscany-experience-in-pisa.a880286.activity-details) ![Pisa and Piazza dei Miracoli Half Day Tour from Florence](https://mediaim.expedia.com/localexpert/558114/ee5005a3-7dc7-4d52-b37b-cb457ae399b1.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Pisa and Piazza dei Miracoli Half Day Tour from Florence CA $50 per adult **88%** of travellers recommend [](https://expedia.ca/things-to-do/pisa-and-piazza-dei-miracoli-half-day-tour-from-florence.a558114.activity-details) ![Micheal Angelo's David](https://mediaim.expedia.com/localexpert/2479829/2bebb71d-abeb-452a-9a00-2b6fddf3b233.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Skip the Line: Florence's Accademia Gallery Priority Entrance Ticket CA $50 per adult **86%** of travellers recommend [](https://expedia.ca/things-to-do/skip-the-line-florences-accademia-gallery-priority-entrance-ticket.a2479829.activity-details) ![Best of Florence Walking Tour](https://mediaim.expedia.com/localexpert/970108/bee6bf2e-9905-40b1-a7e6-463e79154a77.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Best of Florence Walking Tour CA $32 per adult **80%** of travellers recommend [](https://expedia.ca/things-to-do/best-of-florence-walking-tour.a970108.activity-details) ![Florence half day combo tour with David, Uffizi & Duomo](https://mediaim.expedia.com/localexpert/177530/67736287-bdb2-4b4e-a2f9-65e0ac592e0e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Florence Half Day Tour with Uffizi, Michelangelo’s David & Accademia CA $45 per adult **92%** of travellers recommend [](https://expedia.ca/things-to-do/florence-half-day-tour-with-uffizi.a177530.activity-details) [See all activities in Florence](https://expedia.ca/Things-To-Do-In-Florence.d1222.Travel-Guide-Activities) --- ## Santo Spirito Hotel Deals ![Palazzo Mannaioni Suites](https://images.trvl-media.com/lodging/3000000/2530000/2524400/2524373/5017fcc9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Palazzo Mannaioni Suites Via Maffia 9 - 17r Florence FI CA $140 CA $200 total Feb 1 - Feb 2 includes taxes & fees Stay at this residence in Florence. Enjoy free WiFi, concierge services, and satellite TV channels. Our guests praise the helpful staff in our reviews. Popular ... 9.2/10 Wonderful! (1,065 reviews) Everything great. A+ Looking forward to stay again. Reviewed on Jan 21, 2026 [](https://expedia.ca/Hotel-Search?startDate=01%2F02%2F2026&endDate=02%2F02%2F2026&selected=2524373&PinnedHotelID=2524373&HadPinnedHotel=true®ionId=553248633938935375) ![Hotel Horto Convento](https://images.trvl-media.com/lodging/18000000/17940000/17933900/17933824/9c90a529_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Horto Convento Viale Ariosto, 13 Florence FI CA $152 CA $190 total Feb 5 - Feb 6 includes taxes & fees Stay at this hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. Popular ... 9.6/10 Exceptional! (613 reviews) This is an excellent hotel. The room was clean, comfortable, and well appointed. The hotel is beautiful. The staff were very helpful and the breakfast was quite good. It is in a very quiet area so sleeping was easy, but it is still close enough to all the attractions and rests to be walkable. We ... Reviewed on Jan 26, 2026 [](https://expedia.ca/Hotel-Search?startDate=05%2F02%2F2026&endDate=06%2F02%2F2026&selected=17933824&PinnedHotelID=17933824&HadPinnedHotel=true®ionId=553248633938935375) ![UNA Hotels Vittoria Firenze](https://images.trvl-media.com/lodging/1000000/910000/905700/905634/534e501f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### UNA Hotels Vittoria Firenze Via Pisana 59 Florence FI Book a stay at this boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ... 8.4/10 Very Good! (987 reviews) Perfect stay! Not only was the check-in smooth, but everything else was also satisfying. The breakfast was delicious, the staff were friendly, and the location was ideal. There wasn't a single thing I didn't like. I’ll definitely be back! Reviewed on Jan 1, 2026 [Get rates](https://expedia.ca/Hotel-Search?startDate=13%2F02%2F2026&endDate=14%2F02%2F2026&selected=905634&PinnedHotelID=905634&HadPinnedHotel=true®ionId=553248633938935375) [](https://expedia.ca/Hotel-Search?startDate=13%2F02%2F2026&endDate=14%2F02%2F2026&selected=905634&PinnedHotelID=905634&HadPinnedHotel=true®ionId=553248633938935375) ![La Torre Del Cestello](https://images.trvl-media.com/lodging/12000000/11930000/11925300/11925245/b6c3d47f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### La Torre Del Cestello Via Borgo San Frediano, 8 Florence FI CA $298 CA $351 total Feb 14 - Feb 15 includes taxes & fees Stay at this residence in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Popular attractions Pitti Palace and Ponte Vecchio are ... 9/10 Wonderful! (232 reviews) The Torre del Cestello had the "Room with a View" (complete with garden below) that I had been dreaming of for my first visit to Florence. The desk staff were all pleasant, helpful, and set me up with a map and suggestions when I checked in. There was easy access in and out of the room. Quiet but ... Reviewed on Jan 18, 2026 [](https://expedia.ca/Hotel-Search?startDate=14%2F02%2F2026&endDate=15%2F02%2F2026&selected=11925245&PinnedHotelID=11925245&HadPinnedHotel=true®ionId=553248633938935375) ![Casa Santo Nome di Gesù](https://images.trvl-media.com/lodging/18000000/17910000/17907800/17907720/7a971b8e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Casa Santo Nome di Gesù Piazza del Carmine, 21 Florence FI Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ... 8.8/10 Excellent! (342 reviews) Really a nice place, like the room style and good for family stay! Reviewed on Jan 1, 2026 [Get rates](https://expedia.ca/Hotel-Search?startDate=13%2F02%2F2026&endDate=14%2F02%2F2026&selected=17907720&PinnedHotelID=17907720&HadPinnedHotel=true®ionId=553248633938935375) [](https://expedia.ca/Hotel-Search?startDate=13%2F02%2F2026&endDate=14%2F02%2F2026&selected=17907720&PinnedHotelID=17907720&HadPinnedHotel=true®ionId=553248633938935375) ![Santo Spirito Venti](https://images.trvl-media.com/lodging/43000000/42250000/42240100/42240013/00bfb23e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Santo Spirito Venti Via Santo Spirito 20 Florence FI Stay at this B&B in Florence. Enjoy free WiFi, breakfast (surcharge), and an airport shuttle (surcharge). Popular attractions Pitti Palace and Ponte Vecchio ... 8.6/10 Excellent! (59 reviews) The Santo Spirito Venti is in a great location if you want to be close to the Piazza Santa Maria Novella area but want to avoid the noise and crowdedness. It is near a lot of good restaurants. The room was clean and there were enough room for my three kids and me. No complaints but some things of ... Reviewed on Nov 30, 2025 [Get rates](https://expedia.ca/Hotel-Search?startDate=13%2F02%2F2026&endDate=14%2F02%2F2026&selected=42240013&PinnedHotelID=42240013&HadPinnedHotel=true®ionId=553248633938935375) [](https://expedia.ca/Hotel-Search?startDate=13%2F02%2F2026&endDate=14%2F02%2F2026&selected=42240013&PinnedHotelID=42240013&HadPinnedHotel=true®ionId=553248633938935375) [See all 480 properties in Santo Spirito](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=31%2F01%2F2026&endDate=01%2F02%2F2026®ionId=553248633938935375) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Santo Spirito hotel availability [Tonight ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2026-01-30&endDate=2026-01-31)[Jan 30 - Jan 31](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2026-01-30&endDate=2026-01-31) [Tomorrow night ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2026-01-31&endDate=2026-02-01)[Jan 31 - Feb 1](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2026-01-31&endDate=2026-02-01) [This weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=30%2F01%2F2026&endDate=01%2F02%2F2026)[Jan 30 - Feb 1](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=30%2F01%2F2026&endDate=01%2F02%2F2026) --- ### Other neighbourhoods around Santo Spirito ![Brancacci Chapel which includes a church or cathedral and heritage architecture](https://images.trvl-media.com/place/6143202/1907daa8-9b9f-4b02-8d0a-120fd0d47a75.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### San Frediano San Frediano is popular for its stunning river views, and if you're looking for more to see and do, you might think about a trip to Piazza Santo Spirito or Boboli Gardens. [](https://expedia.ca/Florence-San-Frediano.dx6141947) ![Arcetri which includes a river or creek, a sunset and a bridge](https://images.trvl-media.com/place/6141938/199010d8-e112-4eac-a1fa-328c98245fb2.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Oltrarno 4.5/5(77 area reviews) South of the River Arno, this quarter boasts part of Florence's historic center, featuring notable sites like Santo Spirito di Firenze, Palazzo Pitti, Belvedere, and Piazzale Michelangelo. [](https://expedia.ca/Florence-Oltrarno.dx6084345) ![Santa Maria Novella which includes heritage architecture, a church or cathedral and street scenes](https://images.trvl-media.com/place/6084343/def994ac-70f7-40cd-89a8-ec519f783ac9.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Santa Maria Novella 4.5/5(225 area reviews) Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato. [](https://expedia.ca/Florence-Santa-Maria-Novella.dx6084343) ![Ponte Vecchio showing a bridge and a river or creek](https://images.trvl-media.com/place/6075434/7c194037-41c2-40fb-a601-3da01105de7b.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### San Giovanni If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing. [](https://expedia.ca/Florence-San-Giovanni.dx553248635976383065) ![Arcetri showing a bridge and a river or creek](https://images.trvl-media.com/place/6075434/96ba5e7b-ca43-4d9f-9921-bde07164fcbc.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Historic Centre of Florence Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza di Santa Maria Novella and Via de' Calzaiuoli are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city. [](https://expedia.ca/Florence-Historic-Centre-Of-Florence.dx6141938) ![Duomo featuring heritage architecture and street scenes as well as a small group of people](https://images.trvl-media.com/place/6141938/4816fa4b-dceb-4db3-bc3d-7fd0a5eb8789.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Duomo 5/5(339 area reviews) Piazza di Santa Maria Novella and Via de' Calzaiuoli are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops. [](https://expedia.ca/Florence-Duomo.dx6084346) --- --- - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # Santo Spirito ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [4 Star Hotels in Florence ](https://www.expedia.ca/4Star-Florence-Hotels.s40-0-d1222.Travel-Guide-Filter-Hotels) - [Hotels near Boboli Gardens ](https://www.expedia.ca/Boboli-Gardens-Hotels.0-l507684-0.Travel-Guide-Filter-Hotels) - [Winery Hotels in Province of Florence ](https://www.expedia.ca/Destinations-In-Province-Of-Florence-Winery-Hotel.0-0-d179893-tWineryHotel.Hotel-Filter-Destinations) - [Province of Florence Hotels ](https://www.expedia.ca/Destinations-In-Province-Of-Florence.d179893.Hotel-Destinations) - [All Inclusive Resorts and in Tuscany ](https://www.expedia.ca/Destinations-In-Tuscany-All-Inclusive-Hotel.0-0-d601686-tAllInclusiveHotel.Hotel-Filter-Destinations) - 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