Title: Hotels by Independent in East Prairie from CA $84 | Expedia.ca [East Prairie Travel Guide](https://expedia.ca/East-Prairie.dx3000349349)[Hotels in East Prairie](https://expedia.ca/East-Prairie-Hotels.d3000349349.Travel-Guide-Hotels)[Vacation Rentals in East Prairie](https://expedia.ca/East-Prairie-Vacation-Rentals.d3000349349.Travel-Guide-VacationRentals)[Flights to East Prairie](https://expedia.ca/Cheap-Flights-To-East-Prairie.d3000349349.Travel-Guide-Flights)[East Prairie Car Rentals](https://expedia.ca/Car-Rentals-In-East-Prairie.d3000349349.Car-Rental-Guide)[East Prairie Vacation Packages](https://expedia.ca/East-Prairie.d3000349349.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Independent in East Prairie from CA $84 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Nov 4 - Nov 5](https://www.expedia.ca/Hotel-Search?regionId=3000349349&startDate=2025-11-04&endDate=2025-11-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 5 - Nov 6](https://www.expedia.ca/Hotel-Search?regionId=3000349349&startDate=2025-11-05&endDate=2025-11-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=3000349349&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=3000349349&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top East Prairie Independent Hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/d5d0cfa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/4329af11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/e7b8b662.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) Sikeston 8.4/10 Very good (702) "Very quiet and comfortable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lana CA $79 CA $91 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/22000000/21830000/21826900/21826840/w1290h938x0y0-9734f59a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 King Bed, Non Smoking, Microwave](https://images.trvl-media.com/lodging/22000000/21830000/21826900/21826840/73298be5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 King Bed, Non Smoking, Microwave](https://images.trvl-media.com/lodging/22000000/21830000/21826900/21826840/c064d51d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/22000000/21830000/21826900/21826840/3817bb3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hospitality House Union City I 69 / US 51 Union City 6.8/10 (353) "I found the staff to be great. My room was large, clean and in good repair. Parking plentiful. I will definitely stay here again when in the area." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donna CA $76 CA $91 total includes taxes & fees Dec 3 - Dec 4 [](https://www.expedia.ca/Union-City-Hotels-Hospitality-House.h21826840.Hotel-Information) ![Premier Room, 1 Bedroom, Non Smoking](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/2d9e6936.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Room, 1 Bedroom, Non Smoking](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/06367e7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/91bb8871.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Room, 1 Bedroom, Non Smoking | Bathroom](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/5fa7b845.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### New Orleans Inn Portageville Portageville 8.0/10 Very good (715) "Very friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rachel [](https://www.expedia.ca/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information) ![Handicap Room](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/755237c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/e0fa396b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/45782657.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/60633b31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Reelfoot Lake Inn Tiptonville 7.2/10 Good (456) "The room was filthy and smelled so bad we could not stay and lost a whole weeks rent. I cleaned when we went in but nothing could be done about the smell and spiders. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sherry CA $85 CA $98 total includes taxes & fees Nov 13 - Nov 14 [](https://www.expedia.ca/Union-City-Hotels-Reelfoot-Lake-Inn.h16769945.Hotel-Information) ![Gazebo](https://images.trvl-media.com/lodging/17000000/16090000/16087600/16087543/501c540f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free on-the-go breakfast](https://images.trvl-media.com/lodging/17000000/16090000/16087600/16087543/f23217d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/17000000/16090000/16087600/16087543/825a993b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Soundproofing, free WiFi, bed sheets](https://images.trvl-media.com/lodging/17000000/16090000/16087600/16087543/a3f1cfc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travel Inn Marston 5.8/10 (113) "Everything was great except for the wifi issue. They said there was wifi and gav3ca password but it didnt work. I called the front desk and was told they might havevto reset it. Not sure bc i never got to use it. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle [](https://www.expedia.ca/Hayti-Hotels-Travel-Inn.h16087543.Hotel-Information) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/b7b36182.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/980dd49e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/b7350700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/131ce4dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Yard Inn and Suite Sikeston 6.8/10 (112) "Property is a little old. Needs some improvements. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dean CA $70 CA $84 total includes taxes & fees Nov 26 - Nov 27 [](https://www.expedia.ca/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/37000000/36090000/36089000/36088974/09116238.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/37000000/36090000/36089000/36088974/e92c13f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/37000000/36090000/36089000/36088974/ff6f2d55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/37000000/36090000/36089000/36088974/b7a606eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Duck Hunting, Fishing or Relaxing Family Vacation Hornbeak 10/10 Exceptional (214) "Extremely clean and cozy. Deck to the lake is perfection with great sunset views! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Evelyn J. [](https://www.expedia.ca/Hornbeak-Hotels-Duck-Hunting.h36088974.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/84000000/83510000/83500500/83500478/dbfefe0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, in-room safe, free WiFi, bed sheets](https://images.trvl-media.com/lodging/84000000/83510000/83500500/83500478/de4a4d77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/84000000/83510000/83500500/83500478/687381a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/84000000/83510000/83500500/83500478/e2bb5e74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Premier lodging at Reelfoot lake , First class upgrade! Hornbeak 9.8/10 Exceptional (51) "Great place to stay for a fishing trip with friends.Has a nice fish cleaning building." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tim R. [](https://www.expedia.ca/Hornbeak-Hotels-Premier-Lodging-At-Reelfoot-Lake.h83500478.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/76000000/75270000/75267600/75267595/5199219e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/76000000/75270000/75267600/75267595/744e7e66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/76000000/75270000/75267600/75267595/ecbaa404.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, free WiFi](https://images.trvl-media.com/lodging/76000000/75270000/75267600/75267595/db8cf56a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beautiful Reelfoot Lake Tiptonville 10/10 Exceptional (85) "Plenty of room for our family and is located in a quiet neighborhood. Always super clean as well! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amanda F. [](https://www.expedia.ca/Tiptonville-Hotels-Beautiful-Reelfoot-Lake.h75267595.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/90000000/89880000/89872800/89872735/96df576d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/90000000/89880000/89872800/89872735/33bcdf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/90000000/89880000/89872800/89872735/3c043a97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/90000000/89880000/89872800/89872735/48099d18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Great location just across the street from Reelfoot Lake close to boat ramps Hornbeak 9.8/10 Exceptional (71) "Great place to spend a few days." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Johnny R. CA $141 CA $252 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Hornbeak-Hotels-Great-Location-Just-Across-The-Street-From-Reelfoot-Lake-Close-To-Boat-Ramps.h89872735.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-18&endDate=2025-11-19®ionId=3000349349&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FEast-Prairie-Hotels-Independent.0-0-d3000349349--bIndependent.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FEast-Prairie-Hotels-Independent.0-0-d3000349349--bIndependent.Travel-Guide-Filter-Hotels) ## Top East Prairie Hotel Reviews ![Drury Inn & Suites Sikeston, MO](//images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Clean room, great location and friendly staff" [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Pear Tree Inn Sikeston](//images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85_y.jpg) ### Pear Tree Inn Sikeston 10/10 Excellent "Good breakfast options. Reasonable rate. Clean" [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Days Inn and Suites by Wyndham Sikeston](//images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg) ### Days Inn and Suites by Wyndham Sikeston 10/10 Excellent "Yes " [](https://expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Sleep Inn at Discovery Park of America](//images.trvl-media.com/lodging/39000000/38310000/38309600/38309567/2a51d3d0_y.jpg) ### Sleep Inn at Discovery Park of America 10/10 Excellent "Awesome room wonderful breakfast great staff" [](https://expedia.ca/Union-City-Hotels-Sleep-Inn.h38309567.Hotel-Information) ![ For Larger Groups Up To 24, Right on Reelfoot Lake--Private Dock And Pier.](//images.trvl-media.com/lodging/35000000/34330000/34322400/34322352/537131b5_y.jpg) ### For Larger Groups Up To 24, Right on Reelfoot Lake--Private Dock And Pier. 10/10 Excellent "Cypress Knee Lodge was a great gathering place for our hiking group. After nearly 20 years we don't hike much anymore, we are more of a card playing group now! We enjoyed the space, the views, the location, and the accommodations in general. All of this prove to be important because it rained every day we were at Reelfoot Lake. Watching hundreds of pelicans, cormorants, coots, and various other ducks was an added bonus! We would definitely stay here again. Thanks, Jim!" [](https://expedia.ca/Hornbeak-Hotels-For-Larger-Groups-Right-On-Reelfoot-Lake-Private-Dock-And-Pier.h34322352.Hotel-Information) ![Hospitality House Union City I 69 / US 51](//images.trvl-media.com/lodging/22000000/21830000/21826900/21826840/w1290h938x0y0-9734f59a_y.jpg) ### Hospitality House Union City I 69 / US 51 10/10 Excellent "Upgraded to a king suite at no additional costs. Receptionst was very friendly and helpful." [](https://expedia.ca/Union-City-Hotels-Hospitality-House.h21826840.Hotel-Information) ![Hampton Inn Sikeston](//images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg) ### Hampton Inn Sikeston 10/10 Excellent "We had a great room. It was clean and the staff was friendly and helpful. The only thing that happened was the elevators went out during the night. I would definitely stay there again. " [](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Super 8 by Wyndham Charleston/Sikeston East MO](//images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39_y.jpg) ### Super 8 by Wyndham Charleston/Sikeston East MO 10/10 Excellent "Great experience " [](https://expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) ![Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)](//images.trvl-media.com/lodging/1000000/40000/34800/34745/c7be0f94_y.jpg) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) 10/10 Excellent "Courteous staff. Clean, and a large room." 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