Default HTG hotel image

Find hotels in Cairo, MO from CA $102

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 9 - Aug 10
Tomorrow
Aug 10 - Aug 11
Next weekend
Aug 14 - Aug 16
In two weeks
Aug 21 - Aug 23

Filter by

Star rating

Guest rating

Our top choices for Cairo hotels

1. Super 8 by Wyndham Moberly MO

Super 8 by Wyndham Moberly MO
Moberly
United States
Ramona
CA $113
CA $127 total
includes taxes & fees
Aug 16 - Aug 17
Super 8 by Wyndham Moberly MO

2. Comfort Inn & Suites Moberly

Comfort Inn & Suites Moberly
Moberly
United States
Lorrie
CA $156
CA $175 total
includes taxes & fees
Aug 29 - Aug 30
Comfort Inn & Suites Moberly

3. Travelier Motel

Travelier Motel
Macon
United States
Jessica
CA $88
CA $105 total
includes taxes & fees
Aug 10 - Aug 11
Travelier Motel

4. Americas Best Value Inn & Suites Macon at Sunset Dr

Americas Best Value Inn & Suites Macon at Sunset Dr
Macon
United States
William
CA $95
CA $102 total
includes taxes & fees
Aug 23 - Aug 24
Americas Best Value Inn & Suites Macon at Sunset Dr

5. Simple Rewards Inn Shelbina

Simple Rewards Inn Shelbina
Shelbina
United States
Jason
CA $118
CA $130 total
includes taxes & fees
Aug 11 - Aug 12
Simple Rewards Inn Shelbina

6. Super 8 by Wyndham Macon

Super 8 by Wyndham Macon
Macon
United States
KARL
CA $121
CA $132 total
includes taxes & fees
Sep 5 - Sep 6
Super 8 by Wyndham Macon
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Top Cairo Hotel Reviews

Travelier Motel

Travelier Motel

8/10 Good
"Small room but clean and close to the parking. Air conditioning worked great and bed was comfortable. Staff was very good at addressing any questions or requests. Great value for the trip."
Angie 1-night trip
Posted 8 hours ago
Travelier Motel
Super 8 by Wyndham Macon

Super 8 by Wyndham Macon

8/10 Good
"Decent price"
Kevin 1-night trip
Posted 4 days ago
Super 8 by Wyndham Macon
Unwind on Vine

Unwind on Vine

10/10 Excellent
"We enjoy our stay in Macon and the location was perfect."
Amy S. 1-night trip
Posted 7 days ago
Unwind on Vine
Americas Best Value Inn & Suites Macon at Sunset Dr

Americas Best Value Inn & Suites Macon at Sunset Dr

10/10 Excellent
"The staff was excellent ELEVATOR WAS NOT OPERATING COMPUTERS WAS DOWN BREAKFAST WAS NOT VERY GOOD ,NOT MANY ITEMS DRINK MACHINE WAS DOWM"
JOSEPH 2-night trip
Posted 13 days ago
Americas Best Value Inn & Suites Macon at Sunset Dr
'Grace Place' Clark House on Farm: Shared Hot Tub!

'Grace Place' Clark House on Farm: Shared Hot Tub!

10/10 Excellent
"Space was wonderful and a short drive from Finger Lakes State Park for some kayaking. A wonderful place to spend the weekend."
Elyse V. 3-night trip
Posted 3 weeks ago
'Grace Place' Clark House on Farm: Shared Hot Tub!
Kimberly's Hope Clark Apt on Farm w/ Pool Access

Kimberly's Hope Clark Apt on Farm w/ Pool Access

10/10 Excellent
"Absolutely love staying here! It’s so beautiful and we always have soo much funnn! We hope to be back next year!"
Lauren
Posted 3 weeks ago
Kimberly's Hope Clark Apt on Farm w/ Pool Access
Peaceful Lakeside Getaway with Private Dock surrounded with Serene Wilderness

Peaceful Lakeside Getaway with Private Dock surrounded with Serene Wilderness

10/10 Excellent
"Resting and relaxing on a comfortable bed and couches. Perfect outdoor furniture for morning coffee, meals, or an evening game and drink. Fishing and kayaking on the secluded, peaceful, easy to access lake. Also close, easy drive back to town if needed. We loved this cabin! 10/10 recommend!!!"
Julinne M. 3-night trip
Posted 3 weeks ago
Peaceful Lakeside Getaway with Private Dock surrounded with Serene Wilderness
Teal Nest - at The Lodges of Long Branch

Teal Nest - at The Lodges of Long Branch

10/10 Excellent
"Great spot to lay your head after a hot summer day. Sonja always has the air conditioning going and it's nice a cool when we arrive late after fireworks. Very clean with a lot of attention to the details that make your stay comfortable. We are never disappointed."
Jill M. 1-night trip
Posted 1 month ago
Teal Nest - at The Lodges of Long Branch
The Rustic Railroad Studio     5 Min to HWY 63            Kitchen + Washer/Dryer

The Rustic Railroad Studio 5 Min to HWY 63 Kitchen + Washer/Dryer

10/10 Excellent
"This is a great little place. It’s charming, clean, stocked with what you need. The bends super comfortable with quality linens and pillows. The kitchen has all the basics and the bathroom is updated. A great experience!"
Kelly W. 2-night trip
Posted 1 month ago
The Rustic Railroad Studio 5 Min to HWY 63 Kitchen + Washer/Dryer

More cheap stays in Cairo

Americas Best Value Inn & Suites Macon at Sunset Dr

Americas Best Value Inn & Suites Macon at Sunset Dr

28933 Sunset Drive Macon MO
CA $95
CA $102 total
Aug 23 - Aug 24
includes taxes & fees
Americas Best Value Inn & Suites Macon at Sunset Dr
Travelier Motel

Travelier Motel

201 E Briggs Dr Macon MO
CA $88
CA $105 total
Aug 10 - Aug 11
includes taxes & fees
Travelier Motel
Super 8 by Wyndham Moberly MO

Super 8 by Wyndham Moberly MO

300 E Highway 24 Moberly MO
CA $113
CA $127 total
Aug 16 - Aug 17
includes taxes & fees
Super 8 by Wyndham Moberly MO
Simple Rewards Inn Shelbina

Simple Rewards Inn Shelbina

711 North Highway 15 Shelbina MO
CA $118
CA $130 total
Aug 11 - Aug 12
includes taxes & fees
Simple Rewards Inn Shelbina
Super 8 by Wyndham Macon

Super 8 by Wyndham Macon

203 E Briggs Dr Macon MO
CA $121
CA $132 total
Sep 5 - Sep 6
includes taxes & fees
Super 8 by Wyndham Macon
Comfort Inn & Suites Moberly

Comfort Inn & Suites Moberly

1801 W Outer Rd Moberly MO
CA $156
CA $175 total
Aug 29 - Aug 30
includes taxes & fees
Comfort Inn & Suites Moberly

Hotels in Cairo with star rating

Frequently asked questions

What is the best area to stay in Cairo?
The best area to stay in Cairo, Missouri, is near the intersection of US-24 and US-63, as this provides the most convenient access to local amenities and onward travel.This area, though not a distinct neighbourhood, is the commercial heart of Cairo. You'll find the town's main gas station, a few local eateries, and the primary access points to the surrounding highways. It's a practical base for exploring the region.For travellers passing through, perhaps on a road trip, staying close to this intersection offers unparalleled convenience. You can easily refuel, grab a bite, and quickly get back on the road without navigating through residential areas.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Cairo.
How much is the nightly rate at a Cairo hotel?
Prices for hotels in Cairo often vary, but you can find a great deal from CA $102 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia