The 10 Best Hotels Near St. Louis Science Center, St. Louis from CA $132

A space shuttle exhibit with a large model of a space shuttle, a red pillar, and informational displays.

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Our top choices for St. Louis Science Center hotels

A conference room with rows of tables and chairs, a patterned carpet, and ceiling lights.

A hotel room with two beds, a TV, a dresser, and a window with curtains.

1. Drury Inn & Suites St. Louis Forest Park

2 km from St. Louis Science Center

Jennifer

CA $207

CA $242 total

includes taxes & fees

Sep 2 - Sep 3

A modern living room with a fireplace, sofas, a coffee table, and a bookshelf.

A modern kitchen with a marble backsplash, built-in bar with stools, and shelves stocked with bottles.

A modern living room with a fireplace, comfortable seating, and a large TV.

A modern hotel lobby with a marble reception desk, a bar area, and a seating space.

2. AC Hotel St. Louis Central West End

Central West End, 1.8 km from St. Louis Science Center

chris

CA $199

CA $234 total

includes taxes & fees

Sep 3 - Sep 4

An outdoor dining area with multiple wooden tables and benches, surrounded by wicker chairs.

A hotel with a covered outdoor area, a car parking lot, and a sign for 'Bell Air SoCoal'.

A modern bar area with a long counter, bar stools, and a television mounted on the wall.

A group of people sitting on a couch in a well-lit room with a large plant and a floor lamp.

3. Hotel Indigo St Louis - Central West End by IHG

Central West End, 1.7 km from St. Louis Science Center

Simon

CA $186

CA $235 total

includes taxes & fees

Sep 27 - Sep 28

A hot tub with a wooden deck, surrounded by a bamboo fence, and string lights.

A spacious dining area with marble tables and chairs, a kitchen in the background, and a modern ceiling design.

A reception area with a Christmas tree, a neon sign, and a Santa Claus figure.

A building with a brick facade, a covered entrance, and a tree adorned with string lights.

4. The West End

Central West End, 2.3 km from St. Louis Science Center

Isabella

CA $109

CA $155 total

includes taxes & fees

Sep 29 - Sep 30

An outdoor dining area with a table and chairs, a neon sign, and a glass railing overlooking a cityscape.

A modern hotel with a prominent 'aloft' sign, a 'WXYZ' sign, and a 'Coming Soon' advertisement on the side.

A pool area with clear water, red lounge chairs, and a view of the outside through large windows.

A modern bar area with seating, a bar counter, and a view of the cityscape.

5. Aloft by Marriott St Louis Central West End

Central West End, 1.8 km from St. Louis Science Center

Khristina

CA $158

CA $184 total

includes taxes & fees

Aug 31 - Sep 1

An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

A hotel room with a bed, a pink sofa, a small table, and a chair. There is a window with a view of a building.

A compact kitchen with a stainless steel microwave, a sink, and a coffee maker.

A modern indoor seating area with a sofa, tables, and chairs.

6. Home2 Suites by Hilton St. Louis/Forest Park

The Grove, 0.9 km from St. Louis Science Center

paullita jeanne

CA $218

CA $254 total

includes taxes & fees

Sep 20 - Sep 21

A modern hotel room with a large bed, a desk with a chair, a blue armchair, a sofa, a TV, and a large window offering a city view.

A hotel room with a sofa, a blue armchair, a desk with a computer, a TV, and a bed.

A spacious lobby with leather sofas, a patterned rug, and a reception desk.

A modern kitchen with wooden cabinets, a central island, and a wall display of packaged goods.

7. DoubleTree by Hilton St. Louis Forest Park

Central West End, 1.3 km from St. Louis Science Center

Kevin

CA $215

CA $253 total

includes taxes & fees

Sep 4 - Sep 5

A spacious foyer with a grand staircase, a piano, and a large rug.

A hallway with wooden doors, a wall-mounted tree decoration, a small table with a plant, and a painting.

A spacious living room with a beige sofa, a dining area with a table and chairs, large windows, and a chandelier.

A spacious dining area with a round glass table, black metal chairs, and a wooden staircase leading to an upper level.

8. White House at Grand Central

3 km from St. Louis Science Center

Triman

CA $109

CA $176 total

includes taxes & fees

Sep 29 - Sep 30

A bedroom with a large bed, a mirror, and a vanity with shelves.

A wall with a large, abstract mirror design.

A room with a grand piano, a round table with a red and white tablecloth, and a statue of a robed figure.

A modern bedroom with a large bed, a sitting area with a sofa and chairs, a vanity with a mirror, and a ceiling fan.

9. Central West End B&B

Central West End, 3 km from St. Louis Science Center

Stacee

CA $219

CA $276 total

includes taxes & fees

Sep 15 - Sep 16

A hotel room with two beds, a chair, a desk, and a large window.

A conference room with a floral carpet, tables with chairs, and a large orange pendant light.

A lobby with seating areas, a reception desk, and a view through glass doors.

A bathroom with a bathtub, toilet, and sink.

10. Forest Park Hotel by MDR

The Hill, 1.8 km from St. Louis Science Center

wahwah

CA $107

CA $132 total

includes taxes & fees

Sep 27 - Sep 28

11. Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave

The Hill, 1.8 km from St. Louis Science Center

LaTonya

CA $117

CA $137 total

includes taxes & fees

Sep 1 - Sep 2

A log cabin with a stone chimney, wooden deck, and a staircase leading to the entrance.

A rustic wooden bed with a quilt, a chair, and a view of the outdoors through a door.

A cozy bedroom with a stone fireplace, a bed with a patterned bedspread, and a television on a wooden stand.

A rustic wooden interior with a wooden bench displaying various animal carvings and a stone wall.

12. The Lodge at Grant's Trail

10.1 km from St. Louis Science Center

Adrian

CA $239

CA $275 total

includes taxes & fees

Sep 6 - Sep 7

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.

A lobby with a reception desk, seating area with sofas and ottomans, and a patterned rug.

A hotel room with a large bed, a desk with a chair, a television, and a wardrobe.

13. Drury Plaza Hotel St. Louis Brentwood

6.5 km from St. Louis Science Center

Eric

CA $189

CA $224 total

includes taxes & fees

Sep 6 - Sep 7

An outdoor patio with a fire pit, seating, and a building in the background.

A modern hotel lobby with a bar area, a large dining table, and a seating area with chairs.

A modern bar area with a digital menu display, a seating area with a long table and chairs, and a wall with a colorful abstract design.

A Courtyard by Marriott hotel with a modern facade, multiple floors, and a well-lit entrance.

14. Courtyard by Marriott St. Louis Brentwood

5.5 km from St. Louis Science Center

MARY

CA $152

CA $186 total

includes taxes & fees

Sep 6 - Sep 7

A multi-story building with a grand entrance, large windows, and a well-lit facade at night.

A hallway with a chandelier, a dining table with chairs, and a vase of flowers.

A wooden table set for a meal under a tent with string lights, surrounded by chairs on a grassy area.

A dining room with two tables, chairs, a chandelier, and a fireplace.

15. Grand Center Inn

3.5 km from St. Louis Science Center

Leon and Janis

CA $214

CA $252 total

includes taxes & fees

Sep 29 - Sep 30

A rooftop terrace with a fire feature, outdoor seating, and a city view.

A modern bar area with round tables and blue chairs, a wooden bar counter, and a television mounted on the wall.

A modern lounge area with a fireplace, a flat-screen TV, and a dining area with chairs and tables.

A hotel with a modern brick facade, large windows, and a well-lit entrance.

16. Residence Inn By Marriott St. Louis Clayton

Clayton, 6.8 km from St. Louis Science Center

Donna

CA $242

CA $291 total

includes taxes & fees

Sep 6 - Sep 7

A modern bar area with a wooden bar counter, black bar stools, and a large wall with city names.

An outdoor seating area with multiple tables and chairs, large umbrellas, and a built-in fire feature against a stone wall.

A modern lounge area with a stone wall, a flat-screen TV, a fireplace, and comfortable seating.

A modern living room with a fireplace, a large forest-themed painting, and a cozy seating area with a sofa and a coffee table.

17. Fairfield Inn & Suites by Marriott St. Louis Downtown

Downtown West, 5 km from St. Louis Science Center

Erik

CA $186

CA $222 total

includes taxes & fees

Sep 6 - Sep 7

An outdoor patio with a stone fire pit, wicker furniture, and a wooden pergola.

A modern lounge area with a sofa, armchairs, a coffee table, and a small dining table with chairs.

A modern dining area with round tables, chairs, and a long wooden table.

A hotel room with two beds, a desk, a chair, a lamp, and a large window.

18. TownePlace Suites by Marriott Brentwood

5.8 km from St. Louis Science Center

EDWARD

CA $188

CA $228 total

includes taxes & fees

Sep 6 - Sep 7

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

A spacious indoor area with multiple wooden tables and chairs, large windows, and a high ceiling with exposed beams.

A spacious indoor area with a high ceiling and large windows, featuring multiple seating areas with sofas and chairs, and a visible outdoor view through the windows.

A hotel room with a bed, a desk, a television, and a lamp.

19. Pear Tree Inn St. Louis Airport

15 km from St. Louis Science Center

Darren

CA $123

CA $145 total

includes taxes & fees

Sep 7 - Sep 8

A rooftop terrace with modern outdoor seating, a fire pit, and a view of the cityscape.

A modern bar area with multiple shelves of bottles, a bar counter, and several black bar stools.

A spacious dining area with round tables, elegant chandeliers, and a city view.

A modern hotel exterior with a dark facade, outdoor seating area, and a sign indicating it is a Marriott hotel.

20. AC Hotel St. Louis Clayton

6.3 km from St. Louis Science Center

Milton

CA $180

CA $210 total

includes taxes & fees

Sep 4 - Sep 5

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Compare popular hotels close to St. Louis Science Center

Property	Star rating	Guest rating
Drury Inn & Suites St. Louis Forest Park	9.4 Exceptional 1,006 reviews	View
AC Hotel St. Louis Central West End	9.0 Wonderful 832 reviews	View
Hotel Indigo St Louis - Central West End by IHG	8.8 Excellent 1,000 reviews	View
The West End	8.6 Excellent 625 reviews	View
Aloft by Marriott St Louis Central West End	8.6 Excellent 1,001 reviews	View

Top St. Louis Science Center Hotel Reviews

The Royal Sonesta Chase Park Plaza St. Louis

10/10 Excellent

"Always try to stay at CPP when in St. Louis. Familiar, great location, quiet, easy in/out."

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

10/10 Excellent

"The room was cozy and the location was great"

AC Hotel St. Louis Central West End

10/10 Excellent

"Very nice and clean. Lots of nice restaurants in the area too."

Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave

8/10 Good

"Clean and friendly but need to upgrade their TV"

Forest Park Hotel by MDR

8/10 Good

"Free parking, clean big room, with microwave and fridge and affordable."

Drury Inn & Suites St. Louis Forest Park

10/10 Excellent

"The breakfast and the happy hour made this place worth it for us! Everyone on staff was super friendly and this was only about 15 mins away from the city museum which was a plus. The pool was great for the kids to play in too"

Hotel Indigo St Louis - Central West End by IHG

8/10 Good

"Sheets were not clean when we arrived. Room was never cleaned when we came back to sleep for the 2nd night."

4BR Near Forest Park Zoo & Missouri Botanical Garden | Free Parking | STL

10/10 Excellent

"Great location that is walkable to the Science Center, a short drive to Forest Park and the Zoo, and a short drive to Busch Stadium. Exactly what we needed for showing our family some of our favorite places in STL. Also has a nice grass backyard for the kids to run about."

Cielo Casa on “The Hill” Walkable and mins away from, BJC, SLU, Downtown + more

10/10 Excellent

"Our stay in St Louis at Cielo Casa on "the hill" was fantastic. I cannot say enough about our host Adam! He is very responsive and took great care of us along with great suggestions as this was our first time in St Louis. The property is centrally located and easy to get downtown to the arch and Cardinals game. A very short drive to Forest Park which includes an amazing zoo and art museum which are both free! How does that happen?! Also, a quick drive to original AB plant which is a fun tour. The hill really is a great fit for us as it is the "little Italy" of St Louis with amazing deli's, coffee shops, plaza and restaurants. We really enjoyed Shaw Coffee, Gioia's deli and Milo's. The property is an older home as you would expect in this area and is well maintained. Only caution I would advise on is lots of steps, although that was fine for us. Parking is easy in front or the back of the property through the alley. Adam takes good care of the property, and you can see the work that has been done. I highly recommend this property and this area."

Other attractions near St. Louis Science Center

A modern building with large glass windows and a garden with red and pink tulips.

Jewel Box

Made of stacked glass in a restored art deco style, this glass house from the 1930s continues to flourish with tropical trees, hanging plants and a large fountain.

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A modern building with large glass windows, surrounded by a garden with red and pink tulips and purple flowers.

Forest Park

9.2/10 (3,389 reviews)

Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.

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A gazebo with columns and a dome roof, surrounded by a pond and greenery.

Pagoda Circle

As one of the cornerstones of Forest Park for about a century, this grassy island and its bandstand offer an excellent concert spot.

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A well-lit building with multiple flags, including the American flag, and a parking area with cars.

The Muny Theater

8.6/10 (7 reviews)

You can enjoy a show at The Muny Theater during your trip to St. Louis. Amble around the area's lush forest or attend a sporting event.

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Highlands Golf & Tennis Center

Catch an event at Highlands Golf & Tennis Center during your trip to St. Louis. Experience the area's great live music or attend a baseball game.

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Atomic Cowboy

Atomic Cowboy is just one of the places to see in St. Louis, so why not enjoy the other things to explore during your travels?

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Atomic by Jamo

Atomic by Jamo is just one of the places to see in St. Louis, so why not enjoy the other things to explore during your travels?

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Frequently asked questions

What's the area like around St. Louis Science Center?

St. Louis Science Center is located in a welcoming area of St. Louis known for its picturesque gardens and sporting events. If you're looking for a convenient place to stay, check out the 68 hotels and other accommodations you'll find within a mile.

Where is the best place to stay near St. Louis Science Center?

Hampton Inn & Suites St. Louis at Forest Park is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.6 mi (1 km) from St. Louis Science Center. Other good options within a short distance include DoubleTree by Hilton St. Louis Forest Park and Home2 Suites by Hilton St. Louis/Forest Park.

How many hotels will I be able to find near St. Louis Science Center?

Expedia has 68 hotels and other accommodations within a mile from St. Louis Science Center.

If I need to cancel the hotel reservation for my stay near St. Louis Science Center, will I receive a refund?

Yes, the majority of hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best options available near St. Louis Science Center.

What can I see and do near St. Louis Science Center?

Cathedral Basilica of St. Louis, St. Louis Art Museum, and Scott Joplin House State Historic Site feature captivating exhibits. St. Louis Union Station, Jewel Box, and Washington Avenue Historic District are monuments to see when you're exploring the area around St. Louis Science Center. You can check out the local talent at The Muny Theater, Fox Theater, and Powell Hall.

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St. Louis Vacation Rentals

Find hotels near St. Louis Science Center, St. Louis from CA $132

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for St. Louis Science Center hotels

1. Drury Inn & Suites St. Louis Forest Park

2. AC Hotel St. Louis Central West End

3. Hotel Indigo St Louis - Central West End by IHG

4. The West End

5. Aloft by Marriott St Louis Central West End

6. Home2 Suites by Hilton St. Louis/Forest Park

7. DoubleTree by Hilton St. Louis Forest Park

8. White House at Grand Central

9. Central West End B&B

10. Forest Park Hotel by MDR

11. Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave

12. The Lodge at Grant's Trail

13. Drury Plaza Hotel St. Louis Brentwood

14. Courtyard by Marriott St. Louis Brentwood

15. Grand Center Inn

16. Residence Inn By Marriott St. Louis Clayton

17. Fairfield Inn & Suites by Marriott St. Louis Downtown

18. TownePlace Suites by Marriott Brentwood

19. Pear Tree Inn St. Louis Airport

20. AC Hotel St. Louis Clayton

Compare popular hotels close to St. Louis Science Center

Top St. Louis Science Center Hotel Reviews

The Royal Sonesta Chase Park Plaza St. Louis

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

AC Hotel St. Louis Central West End

Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave

Forest Park Hotel by MDR

Drury Inn & Suites St. Louis Forest Park

Hotel Indigo St Louis - Central West End by IHG

4BR Near Forest Park Zoo & Missouri Botanical Garden | Free Parking | STL

Cielo Casa on “The Hill” Walkable and mins away from, BJC, SLU, Downtown + more

Other attractions near St. Louis Science Center

Jewel Box

Forest Park

Pagoda Circle

The Muny Theater

Highlands Golf & Tennis Center

Atomic Cowboy

Atomic by Jamo

Frequently asked questions

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