Title: Hotels by Best Western in Southern Illinois from CA $111 | Expedia.ca [Southern Illinois Travel Guide](https://expedia.ca/Southern-Illinois.dx6233859)[Hotels in Southern Illinois](https://expedia.ca/Southern-Illinois-Hotels.d6233859.Travel-Guide-Hotels)[Vacation Rentals in Southern Illinois](https://expedia.ca/Southern-Illinois-Vacation-Rentals.d6233859.Travel-Guide-VacationRentals)[Flights to Southern Illinois](https://expedia.ca/Cheap-Flights-To-Southern-Illinois.d6233859.Travel-Guide-Flights)[Southern Illinois Car Rentals](https://expedia.ca/Car-Rentals-In-Southern-Illinois.d6233859.Car-Rental-Guide)[Southern Illinois Vacation Packages](https://expedia.ca/Southern-Illinois.d6233859.Destination-Travel-Guides) ![Southern Illinois featuring a sunset, forests and landscape views](https://images.trvl-media.com/place/553248635944113522/0e29d2f8-2d58-457a-908d-4b89b13776d9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Southernmost Illinois Tourism Bureau # Find Hotels by Best Western in Southern Illinois from CA $111 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 17 - Dec 18](https://www.expedia.ca/Hotel-Search?regionId=6233859&startDate=2025-12-17&endDate=2025-12-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 18 - Dec 19](https://www.expedia.ca/Hotel-Search?regionId=6233859&startDate=2025-12-18&endDate=2025-12-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6233859&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6233859&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Southern Illinois Best Western ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/3400/3382/w3840h2556x0y4-dd5ad558.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/10000/3400/3382/5f2b59be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/10000/3400/3382/40f05879.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3400/3382/w3837h2560x3y0-d7de35fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Delta Inn [](https://www.expedia.ca/Effingham-Hotels-Best-Western-Delta-Inn.h3382.Hotel-Information) Effingham 9.2/10 Wonderful (1000) "Clean room, courteous staff, nice amenities." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard M CA $116 CA $130 total includes taxes & fees Jan 7 - Jan 8, 2026 [](https://www.expedia.ca/Effingham-Hotels-Best-Western-Delta-Inn.h3382.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/100000/98000/97975/86964c5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/100000/98000/97975/39e99d4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/100000/98000/97975/c372075d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/100000/98000/97975/9cb51690.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Marion Hotel [](https://www.expedia.ca/Carbondale-Hotels-Best-Western-Marion-Hotel.h97975.Hotel-Information) Marion 8.2/10 Very good (1005) "Front staff (Cari) was so friendly and helpful during our stay. Our room was clean and the bed was comfortable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wendy CA $92 CA $111 total includes taxes & fees Jan 14 - Jan 15, 2026 [](https://www.expedia.ca/Carbondale-Hotels-Best-Western-Marion-Hotel.h97975.Hotel-Information) ![Standard Room, 2 Double Beds, Accessible, Refrigerator & Microwave (Pet Friendly)](https://images.trvl-media.com/lodging/1000000/120000/119200/119178/43576f21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/120000/119200/119178/3652a0e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/119200/119178/cffec8b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/120000/119200/119178/8d5c63b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Saluki Inn [](https://www.expedia.ca/Carbondale-Hotels-Best-Western-Saluki-Inn.h119178.Hotel-Information) Carbondale 8.0/10 Very good (1001) "It was fine for the price and location. Good value if all you need is a no frills hotel room, and much better since the re-model. Clean room and staff was friendly and courteous. Easy walk to Buffalo Wild Wings and Fujiyama Japanese Steak House and a few others. Would stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Douglas CA $109 CA $128 total includes taxes & fees Dec 30 - Dec 31 [](https://www.expedia.ca/Carbondale-Hotels-Best-Western-Saluki-Inn.h119178.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/450000/446600/446536/7433f47d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/450000/446600/446536/03c2a370.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/450000/446600/446536/dc813dd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/450000/446600/446536/b28e75cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Troy Hotel [](https://www.expedia.ca/St-Louis-Hotels-Best-Western-Troy-Hotel.h446536.Hotel-Information) Troy 8.2/10 Very good (916) "wonderful stay,would use all hotel stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) larry CA $116 CA $129 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/St-Louis-Hotels-Best-Western-Troy-Hotel.h446536.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/50000/42100/42026/b9a8ecca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/42100/42026/82e04edc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42100/42026/e957049a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/42100/42026/1ab677de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Heartland Inn [](https://www.expedia.ca/Mattoon-Hotels-Best-Western-Heartland-Inn.h42026.Hotel-Information) Mattoon 8.2/10 Very good (552) "Clean room, comfortable beds, good breakfast selection, and friendly front desk staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cristy CA $111 CA $124 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Mattoon-Hotels-Best-Western-Heartland-Inn.h42026.Hotel-Information) ![Suite, 1 King Bed, Non Smoking, Kitchenette (with Sofabed)](https://images.trvl-media.com/lodging/1000000/70000/64500/64405/484b5683.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/70000/64500/64405/c20e75b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/64500/64405/83533a47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/70000/64500/64405/66d488fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Flora Inn [](https://www.expedia.ca/Olney-Hotels-Best-Western-Lorson-Inn.h64405.Hotel-Information) Flora 8.4/10 Very good (295) "Breakfast area very nice and food tasty " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeanette CA $137 CA $150 total includes taxes & fees Dec 18 - Dec 19 [](https://www.expedia.ca/Olney-Hotels-Best-Western-Lorson-Inn.h64405.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/120000/119400/119307/9bba734f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/120000/119400/119307/3a194c80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/120000/119400/119307/86b65f12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/120000/119400/119307/d9118f52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western U. S. Inn [](https://www.expedia.ca/Carlyle-Lake-Hotels-Best-Western-U-S-Inn.h119307.Hotel-Information) Nashville 8.6/10 Excellent (393) "Great and clean hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose CA $151 CA $165 total includes taxes & fees Dec 18 - Dec 19 [](https://www.expedia.ca/Carlyle-Lake-Hotels-Best-Western-U-S-Inn.h119307.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/10000/6200/6183/f3f7bcfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/6200/6183/4bde9a8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/6200/6183/cc1cff17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/6200/6183/a07edb86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western St. Louis Fairview Heights [](https://www.expedia.ca/Fairview-Heights-Hotels-Western-Hotels.h6183.Hotel-Information) Fairview Heights 6.2/10 (122) "The swimming pool heater was broken. The grandkids were disappointed. The rooms are clean and quiet. The staff are friendly and helpful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Heather CA $104 CA $118 total includes taxes & fees Jan 12 - Jan 13, 2026 [](https://www.expedia.ca/Fairview-Heights-Hotels-Western-Hotels.h6183.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-31&endDate=2026-01-01®ionId=6233859&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSouthern-Illinois-Hotels-Best-Western.0-0-d6233859--bBestWestern.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSouthern-Illinois-Hotels-Best-Western.0-0-d6233859--bBestWestern.Travel-Guide-Filter-Hotels) ## Top Southern Illinois Hotel Reviews ![Drury Plaza Hotel Mt. Vernon](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/f9296f7b_y.jpg) ### Drury Plaza Hotel Mt. Vernon 10/10 Excellent "Short weekend, clean room, very bright atmosphere, super clean, great staff, no issues will stay again. " [](https://expedia.ca/Mount-Vernon-Hotels-Drury-Inn-Suites-Mt-Vernon.h42021.Hotel-Information) ![Comfort Suites Mount Vernon](https://images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/b34f836a_y.jpg) ### Comfort Suites Mount Vernon 10/10 Excellent "Very clean, good breakfast included. Night staff was very friendly and good. 😊 " [](https://expedia.ca/Mount-Vernon-Hotels-Comfort-Suites-Mount-Vernon.h1387309.Hotel-Information) ![Drury Inn & Suites St. Louis Fairview Heights](https://images.trvl-media.com/lodging/1000000/50000/41900/41802/c56c0460_y.jpg) ### Drury Inn & Suites St. Louis Fairview Heights 10/10 Excellent "I always stay at Drury whenever I can, you can always count on having a great stay! Clean rooms, complimentary cocktails, Hot breakfast, AND complimentary hors d’oeuvres!! " [](https://expedia.ca/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-Fairview-Heights.h41802.Hotel-Information) ![Drury Inn & Suites St. Louis O'Fallon, IL](https://images.trvl-media.com/lodging/2000000/1550000/1544100/1544028/d2bc121f_y.jpg) ### Drury Inn & Suites St. Louis O'Fallon, IL 10/10 Excellent "The Breakfast was nice and saved us money on the trip. Hotel and rooms were very clean and all the workers were very nice. Local was good for anything you would need and close the St. Louis" [](https://expedia.ca/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-OFallon.h1544028.Hotel-Information) ![Drury Inn & Suites Marion](https://images.trvl-media.com/lodging/1000000/50000/42100/42025/a8315e37_y.jpg) ### Drury Inn & Suites Marion 10/10 Excellent "Breakfast was very good. Dinner was fair." [](https://expedia.ca/Carbondale-Hotels-Drury-Inn-Marion.h42025.Hotel-Information) ![La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis](https://images.trvl-media.com/lodging/1000000/210000/201300/201286/c5041840_y.jpg) ### La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis 8/10 Good "Clean bed and room. Very nice staff" [](https://expedia.ca/Collinsville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-OFallon.h201286.Hotel-Information) ![Hampton Inn & Suites Effingham](https://images.trvl-media.com/lodging/2000000/1330000/1322000/1321975/11916b3a_y.jpg) ### Hampton Inn & Suites Effingham 10/10 Excellent "Great room! Will definitely stay again!" [](https://expedia.ca/Effingham-Hotels-Hampton-Inn-Suites-Effingham.h1321975.Hotel-Information) ![Red Lion Inn & Suites Pontoon Beach](https://images.trvl-media.com/lodging/1000000/20000/17400/17338/284b6d11_y.jpg) ### Red Lion Inn & Suites Pontoon Beach 10/10 Excellent "Room was clean, staff were really nice & helpful!! We will be back!" [](https://expedia.ca/St-Louis-Hotels-Red-Lion-Inn-Suites-Pontoon-Beach.h17338.Hotel-Information) ![Super 8 by Wyndham O'Fallon](https://images.trvl-media.com/lodging/1000000/20000/11100/11071/055d0e3b_y.jpg) ### Super 8 by Wyndham O'Fallon 10/10 Excellent "Staff were very friendly. It was clean & quiet. I will definitely stop again on my next trip. 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