Title: Seneca Inns from CA $108 | Expedia.ca [Hotels in Seneca](https://expedia.ca/Seneca-Hotels.d6548.Travel-Guide-Hotels)[Vacation Rentals in Seneca](https://expedia.ca/Seneca-Vacation-Rentals.d6548.Travel-Guide-VacationRentals)[Flights to Seneca](https://expedia.ca/Cheap-Flights-To-Seneca.d6548.Travel-Guide-Flights)[Seneca Car Rentals](https://expedia.ca/Car-Rentals-In-Seneca.d6548.Car-Rental-Guide)[Seneca Vacation Packages](https://expedia.ca/Seneca.d6548.Destination-Travel-Guides) ![Lake Keowee South Carolina](https://images.trvl-media.com/place/6548/8356140f-bae9-4afc-8d65-c18efc5581aa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6548/8356140f-bae9-4afc-8d65-c18efc5581aa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Feb 27 - Mar 1](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-02-27&endDate=2026-03-01&adults=2&lodging=INN&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Mar 6 - Mar 8](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-03-06&endDate=2026-03-08&adults=2&lodging=INN&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-03-20&endDate=2026-03-22&adults=2&lodging=INN&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Apr 17 - Apr 19](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-04-17&endDate=2026-04-19&adults=2&lodging=INN&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) No exact matches found, but these alternatives could be just right ## Recommended hotels in Seneca ![View from property](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/d7c06df6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/2da98b27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/53271cae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 Queen Bed (View) | Private kitchen](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/60991646.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy [](https://www.expedia.ca/Seneca-Hotels-Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information) Seneca 9.8/10 Exceptional (59 reviews) "Excellent stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Beonca CA $94 CA $163 total includes taxes & fees Mar 11 - Mar 12 [](https://www.expedia.ca/Seneca-Hotels-Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/81c4f249.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/f6f7c8c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/16b3def6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Seneca Clemson Area US-123 [](https://www.expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) Downtown 8.0/10 Very good (678 reviews) "Everting was good" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan CA $106 CA $125 total includes taxes & fees Mar 15 - Mar 16 [](https://www.expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/40d3b059.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/ec808a43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/1da4db10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/89ea8ad4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Clemson Cottage - 3.6 mi. to Memorial Stadium [](https://www.expedia.ca/Seneca-Hotels-The-Clemson-Cottage-36-Mi-To-Memorial-Stadium.h96153668.Hotel-Information) Seneca 10/10 Exceptional (14 reviews) "Adorable and clean home convenient to Clemson’s campus. We enjoyed our stay and Tyler was an exceptional host! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mandy H. CA $245 CA $539 total includes taxes & fees Feb 18 - Feb 19 [](https://www.expedia.ca/Seneca-Hotels-The-Clemson-Cottage-36-Mi-To-Memorial-Stadium.h96153668.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/123000000/122340000/122332400/122332322/w1536h2048x0y0-6998e207.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122340000/122332400/122332322/ad885ebc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/123000000/122340000/122332400/122332322/511c9b4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/123000000/122340000/122332400/122332322/c9812bb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy Clemson TIny House Cabin [](https://www.expedia.ca/Seneca-Hotels-Cozy-Clemson-TIny-House-Cabin.h122332322.Hotel-Information) Seneca CA $170 CA $297 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Seneca-Hotels-Cozy-Clemson-TIny-House-Cabin.h122332322.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/db449d90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/589bd84f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/91e6d418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/6abd26aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakeside Lodge Clemson [](https://www.expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) Seneca 9.0/10 Wonderful (1,004 reviews) "Great place and location, great mattress, " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeffrey CA $148 CA $184 total includes taxes & fees Mar 16 - Mar 17 [](https://www.expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96690000/96683100/96683053/w1290h856x0y0-3209f519.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/97000000/96690000/96683100/96683053/783bd314.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/97000000/96690000/96683100/96683053/e4fb4aee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/97000000/96690000/96683100/96683053/1cece012.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private Room #3 [](https://www.expedia.ca/Seneca-Hotels-Private-Room-3.h96683053.Hotel-Information) Downtown 9.2/10 Wonderful (13 reviews) "Very clean and comfortable! Will stay again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph K. CA $191 CA $302 total includes taxes & fees Feb 18 - Feb 19 [](https://www.expedia.ca/Seneca-Hotels-Private-Room-3.h96683053.Hotel-Information) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96690000/96683400/96683303/w1290h849x0y0-46041109.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/97000000/96690000/96683400/96683303/58429ce4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/97000000/96690000/96683400/96683303/cf717f09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/97000000/96690000/96683400/96683303/8ce3646a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique hotel in historic downtown Seneca. Room #4, King bed. [](https://www.expedia.ca/Seneca-Hotels-Boutique-Hotel-In-Historic-Downtown-Seneca-Room-4.h96683303.Hotel-Information) Downtown 9.6/10 Exceptional (18 reviews) "Great spot! Have stayed several different times and always come back!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashleigh G. CA $191 CA $302 total includes taxes & fees Feb 18 - Feb 19 [](https://www.expedia.ca/Seneca-Hotels-Boutique-Hotel-In-Historic-Downtown-Seneca-Room-4.h96683303.Hotel-Information) ![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100790000/100784300/100784243/67979a9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100790000/100784300/100784243/4513793e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100790000/100784300/100784243/c5a2afe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100790000/100784300/100784243/424e1883.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly! [](https://www.expedia.ca/Seneca-Hotels-Cozy-Camper-In-Clemson-Hills-5-Minutes-From-Clemson-University-Pet-Friendly.h100784243.Hotel-Information) Seneca 10/10 Exceptional (12 reviews) "Very clean and comfortable - very close to Clemson and easy access. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jim A. CA $205 CA $272 total includes taxes & fees Feb 18 - Feb 19 [](https://www.expedia.ca/Seneca-Hotels-Cozy-Camper-In-Clemson-Hills-5-Minutes-From-Clemson-University-Pet-Friendly.h100784243.Hotel-Information) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96690000/96684400/96684378/w1290h856x0y0-36eb931e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/97000000/96690000/96684400/96684378/b874ccca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/97000000/96690000/96684400/96684378/0ea4c48a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/97000000/96690000/96684400/96684378/94a7d324.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique hotel in historic downtown Seneca. Room #6, King Bed. [](https://www.expedia.ca/Seneca-Hotels-Boutique-Hotel-In-Historic-Downtown-Seneca-Room-6.h96684378.Hotel-Information) Downtown 9.2/10 Wonderful (24 reviews) "Great stay. Super cute decor. Loved the location. Will be staying again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) denise n. CA $191 CA $302 total includes taxes & fees Feb 18 - Feb 19 [](https://www.expedia.ca/Seneca-Hotels-Boutique-Hotel-In-Historic-Downtown-Seneca-Room-6.h96684378.Hotel-Information) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96690000/96684200/96684171/e82aa6e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/97000000/96690000/96684200/96684171/51c2fa13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/97000000/96690000/96684200/96684171/7d406dd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/97000000/96690000/96684200/96684171/811b8849.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique hotel in historic downtown Seneca. Room #5, two King beds. [](https://www.expedia.ca/Seneca-Hotels-Boutique-Hotel-In-Historic-Downtown-Seneca-Room-5.h96684171.Hotel-Information) Downtown 9.6/10 Exceptional (15 reviews) "We had a wonderful visit- clean and beautifully decorated. It was a little bit unusual to not have a window but very nice stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rachel L. CA $191 CA $302 total includes taxes & fees Feb 18 - Feb 19 [](https://www.expedia.ca/Seneca-Hotels-Boutique-Hotel-In-Historic-Downtown-Seneca-Room-5.h96684171.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/w4000h2662x0y0-18bf21d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/81e73e39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/e45ab30f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/cc35e730.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites Seneca Clemson Univ Area [](https://www.expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information) Seneca 9.4/10 Exceptional (207 reviews) "Spotless, friendly staff, great location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cari CA $170 CA $187 total includes taxes & fees Mar 19 - Mar 20 [](https://www.expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/51000000/50270000/50261400/50261396/fc19a084.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/51000000/50270000/50261400/50261396/84e2f8d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/51000000/50270000/50261400/50261396/52fb0c78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/51000000/50270000/50261400/50261396/64f3f98d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tucker Farm Cottage on Century Farm [](https://www.expedia.ca/Seneca-Hotels-Tucker-Farm-Cottage-On-Century-Farm.h50261396.Hotel-Information) Seneca 10/10 Exceptional (33 reviews) "Excellent stay, beautiful area!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Barbara W. CA $218 CA $527 total includes taxes & fees Feb 18 - Feb 19 [](https://www.expedia.ca/Seneca-Hotels-Tucker-Farm-Cottage-On-Century-Farm.h50261396.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/83732283.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/b202edd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/62fa3a56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/590fd43d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Seneca Clemson [](https://www.expedia.ca/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information) Seneca 9.2/10 Wonderful (809 reviews) "Perfect stay for a weekend. Lots of shopping and restaurants nearby. Clean safe area annd the staff was wonderful!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cindy CA $148 CA $162 total includes taxes & fees Feb 23 - Feb 24 [](https://www.expedia.ca/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/126000000/125630000/125624500/125624500/fbb953e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/126000000/125630000/125624500/125624500/2d71c6c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/126000000/125630000/125624500/125624500/a6445e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/126000000/125630000/125624500/125624500/891c0bf4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 1-bedroom house in lovely Seneca. 5 miles from Clemson University [](https://www.expedia.ca/Seneca-Hotels-Charming-1-Bedroom-House-In-Lovely-Seneca-5-Miles-From-Clemson-University.h125624500.Hotel-Information) Seneca CA $64 CA $116 total includes taxes & fees Feb 18 - Feb 19 [](https://www.expedia.ca/Seneca-Hotels-Charming-1-Bedroom-House-In-Lovely-Seneca-5-Miles-From-Clemson-University.h125624500.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/e032590e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/518d0c67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cookware/dishes/utensils, paper towels](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/bc9bfba2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/9b29fdfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 3-bedroom house with WiFi and AC in serene Seneca on Lake Hartwell [](https://www.expedia.ca/Seneca-Hotels-Charming-3-Bedroom-House-With-WiFi-And-AC-In-Serene-Seneca-On-Lake-Hartwell.h114542071.Hotel-Information) Seneca 10/10 Exceptional (9 reviews) "We enjoyed our stay. Had everything we needed. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diane S. CA $334 CA $717 total includes taxes & fees Feb 18 - Feb 19 [](https://www.expedia.ca/Seneca-Hotels-Charming-3-Bedroom-House-With-WiFi-And-AC-In-Serene-Seneca-On-Lake-Hartwell.h114542071.Hotel-Information) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/118000000/117650000/117644500/117644416/c0b82041.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop](https://images.trvl-media.com/lodging/118000000/117650000/117644500/117644416/b1844261.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/118000000/117650000/117644500/117644416/c2f5c321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/118000000/117650000/117644500/117644416/5fc6414e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Enjoy one of our RV units son less of a headache for you this vacation! [](https://www.expedia.ca/Seneca-Hotels-Cozy-Campground-In-Enchanting-Seneca-With-AC.h117644416.Hotel-Information) Seneca 8.0/10 Very good (4 reviews) "My partner and I stayed 5 nights and we enjoyed it so much. It's such a convenient place to reside for a get away. If you're looking for that "outback" feeling but want to be cozy; look no further. Communication was always qick with responses and was more than willing to help with anything we needed! We would definitely stay again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Denise s. CA $95 CA $209 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/Seneca-Hotels-Cozy-Campground-In-Enchanting-Seneca-With-AC.h117644416.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/56ab80ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free cribs/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/0d1cab6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/72b1141f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/dac98c3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Seneca / Clemson Area [](https://www.expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Seneca-Clemson-Area.h14854.Hotel-Information) Seneca 6.8/10 (726 reviews) "Room was clean. Quiet place to rest. Lisa at the front desk was very helpful and very nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Teresa CA $99 CA $108 total includes taxes & fees Feb 26 - Feb 27 [](https://www.expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Seneca-Clemson-Area.h14854.Hotel-Information) ![Standard Room, 1 King Bed, Non Smoking, Jetted Tub](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/eaa8fc9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/a9edd66e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/d223eeb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/83901eb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Seneca-Clemson [](https://www.expedia.ca/Anderson-Hotels-Best-Western-Seneca-Clemson.h517561.Hotel-Information) Seneca 8.4/10 Very good (649 reviews) "The stay was amazing " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tabatha CA $126 CA $139 total includes taxes & fees Feb 23 - Feb 24 [](https://www.expedia.ca/Anderson-Hotels-Best-Western-Seneca-Clemson.h517561.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/7bfcd263.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/bf812e86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, table tennis](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/1692b12e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/8d32bcc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 3-bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson [](https://www.expedia.ca/Seneca-Hotels-3-Bedroom-2-Bath-Home-Located-Minutes-From-Keowee-Mariana.h118704946.Hotel-Information) Seneca 10/10 Exceptional (5 reviews) "Great place with a lot close by" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aldor D. CA $290 CA $431 total includes taxes & fees Feb 18 - Feb 19 [](https://www.expedia.ca/Seneca-Hotels-3-Bedroom-2-Bath-Home-Located-Minutes-From-Keowee-Mariana.h118704946.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/8f736b3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/1436aba9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/313b57b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/aca2d330.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Seneca-Clemson Area [](https://www.expedia.ca/Anderson-Hotels-Hampton-Inn-Suites-Seneca-Clemson-Area.h6696886.Hotel-Information) Seneca 9.2/10 Wonderful (680 reviews) "Everything was excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debby CA $168 CA $185 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Anderson-Hotels-Hampton-Inn-Suites-Seneca-Clemson-Area.h6696886.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-03&endDate=2026-03-04®ionId=6548&adults=2&lodging=INN&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=AA_SPRING_PROMO_6548) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSeneca-Inns.d6548-aaInns.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSeneca-Inns.d6548-aaInns.Travel-Guide-Accommodation) ## Top Seneca Hotel Reviews ![Hampton Inn & Suites Seneca-Clemson Area](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/1436aba9_y.jpg) ### Hampton Inn & Suites Seneca-Clemson Area 10/10 Excellent "yes" [](https://expedia.ca/Anderson-Hotels-Hampton-Inn-Suites-Seneca-Clemson-Area.h6696886.Hotel-Information) ![Lakeside Lodge Clemson](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/9732d3ff_y.jpg) ### Lakeside Lodge Clemson 10/10 Excellent "Great place and location, great mattress, " [](https://expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) ![Quality Inn Seneca Clemson Area US-123](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2_y.jpg) ### Quality Inn Seneca Clemson Area US-123 10/10 Excellent "Everting was good" [](https://expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) ![Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/8c11b789_y.jpg) ### Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy 10/10 Excellent "THE ABSOLUTE BEST from the staff that accommodated every request I had, the views, the welcoming kit, very very clean. Perfect getaway with the kids. Can’t wait to go back for an adult weekend! " [](https://expedia.ca/Seneca-Hotels-Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information) ![Tru by Hilton Seneca Clemson](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/10f1fcf8_y.jpg) ### Tru by Hilton Seneca Clemson 10/10 Excellent "Everything is good!!! " [](https://expedia.ca/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information) ![Days Inn by Wyndham Seneca / Clemson Area](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/9f69229a_y.jpg) ### Days Inn by Wyndham Seneca / Clemson Area 10/10 Excellent "Room was very clean and the staff are great. " [](https://expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Seneca-Clemson-Area.h14854.Hotel-Information) ![5🌟 Modern Lakefront Luxury Oasis 🇺🇸 270° Lake Views w/Dock & Hot Tub!](https://images.trvl-media.com/lodging/62000000/61020000/61010400/61010330/fa789e5c_y.jpg) ### 5🌟 Modern Lakefront Luxury Oasis 🇺🇸 270° Lake Views w/Dock & Hot Tub! 10/10 Excellent "What a wonderful place for our family gathering. The large commons area provided beautiful views of the lake. There were a variety of places to play games and enjoy our time together." [](https://expedia.ca/Seneca-Hotels-Modern-Lakefront-Luxury-Oasis-270-Lake-Views-WDock.h61010330.Hotel-Information) ![Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock](https://images.trvl-media.com/lodging/28000000/27120000/27118400/27118346/67cc829e_y.jpg) ### Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock 10/10 Excellent "We will definitely be booking this property again. We usually have family gathering inJanuary and I think this will be our new location. It accommodated those lodging with us and who came to visit while we were there. The flow of the house and outdoors was so convenient especially for our large gathering when we roasted oysters. " [](https://expedia.ca/Seneca-Hotels-Quiet-Cove.h27118346.Hotel-Information) ![Fairfield Inn & Suites Seneca Clemson Univ Area ](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/9fe06894_y.jpg) ### Fairfield Inn & Suites Seneca Clemson Univ Area 10/10 Excellent "Spotless, friendly staff, great location. " [](https://expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information) ## Find out more about Seneca ## Seneca Inns information | Number of reviews | 4,943 | | ----------------- | ------- | | Accommodation | 0 Inns | | Lowest Price | CA $108 | | Highest Price | CA $717 | ## Frequently asked questions ### Why book your Seneca inn with Expedia? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [Aparthotels in Central ](https://www.expedia.ca/Central-Apart-Hotels.d10503-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Central ](https://www.expedia.ca/Central-Bed-And-Breakfast.d10503-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Boutique Hotels in Central ](https://www.expedia.ca/Central-Hotels-Boutique-Hotel.0-0-d10503-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Business Hotels in Central ](https://www.expedia.ca/Central-Hotels-Business-Hotel.0-0-d10503-tBusinessHotel.Travel-Guide-Filter-Hotels) - 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