Title: Hotels by Best Western in Santee | Expedia.ca [Santee Travel Guide](https://expedia.ca/Santee.dx9953)[Hotels in Santee](https://expedia.ca/Santee-Hotels.d9953.Travel-Guide-Hotels)[Vacation Rentals in Santee](https://expedia.ca/Santee-Vacation-Rentals.d9953.Travel-Guide-VacationRentals)[Flights to Santee](https://expedia.ca/Cheap-Flights-To-Santee.d9953.Travel-Guide-Flights)[Santee Car Rentals](https://expedia.ca/Car-Rentals-In-Santee.d9953.Car-Rental-Guide)[Santee Vacation Packages](https://expedia.ca/Santee.d9953.Destination-Travel-Guides) ![Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina](https://images.trvl-media.com/place/9953/cd2a687d-b68e-41e2-9556-82dcf249bc2d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/9953/cd2a687d-b68e-41e2-9556-82dcf249bc2d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Mar 10 - Mar 11](https://www.expedia.ca/Hotel-Search?regionId=9953&startDate=2026-03-10&endDate=2026-03-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 11 - Mar 12](https://www.expedia.ca/Hotel-Search?regionId=9953&startDate=2026-03-11&endDate=2026-03-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=9953&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=9953&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Hotels-Best-Western.0-0-d9953--bBestWestern.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Hotels-Best-Western.0-0-d9953--bBestWestern.Travel-Guide-Filter-Hotels) ## Top Santee Hotel Reviews ![Spark by Hilton Orangeburg](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3840h2556x0y4-5cb4ef80_y.jpg) ### Spark by Hilton Orangeburg 10/10 Excellent "Nice work out center .It was quiet . rooms was spacious . Check in quick and easy . Staff vey friendly outside well lit" [](https://expedia.ca/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) ![SpringHill Suites by Marriott Orangeburg](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/27e78d69_y.jpg) ### SpringHill Suites by Marriott Orangeburg 8/10 Good "Bed was a little to soft breakfast could have been a whole lot better overalls stay was great" [](https://expedia.ca/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information) ![Tru by Hilton Orangeburg](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/99c8fb35_y.jpg) ### Tru by Hilton Orangeburg 10/10 Excellent "Didn't use business facility. Parking was safe." [](https://expedia.ca/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/4b412627_y.jpg) ### Tru By Hilton Santee 8/10 Good "The hotel room was clean, had a lot of towels. Was able to walk around the building for exercise. Cracker Barrel next door. Bed and pillows were uncomfortable. The water pressure in the shower was awful. Had hot water but the pressure was very low. They have a sign for quiet time in the hotel but we had someone upstairs making noise from 9 pm to almost 11 and the person next to us as well. The hotel itself is nice. The breakfast needs a bigger variety of food. Had bagels and bread. Could have english muffins or danish besides those. People at the front desk were nice. Would use this hotel again but they have to crack down on the noise in the building. Lack of rugs in the rooms does not help. Please have a better selection of foods at breakfast." [](https://expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![SureStay Hotel by Best Western Manning](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/27faffbf_y.jpg) ### SureStay Hotel by Best Western Manning 10/10 Excellent "Very clean" [](https://expedia.ca/Sumter-Hotels-SureStay-Hotel-By-Best-Western-Manning.h569301.Hotel-Information) ![Super 8 by Wyndham Santee](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/2fd60881_y.jpg) ### Super 8 by Wyndham Santee 8/10 Good "The beds are super comfy. I liked how quiet it was in the room and the staff was very friendly " [](https://expedia.ca/Orangeburg-Hotels-Super-8-By-Wyndham-Santee.h1050011.Hotel-Information) ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/d2da67e4_y.jpg) ### Baymont by Wyndham Santee 4/10 Poor "The room could have been cleaner around the sink. There was a used towel hanging on the bathroom door, and the body wash was empty. Okay besides that. " [](https://expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!](https://images.trvl-media.com/lodging/92000000/91790000/91788500/91788460/c321e70e_y.jpg) ### Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95! 10/10 Excellent "Everything was great and host was very responsive. We had a few notes we passed on to the host and they were very quick to respond. The exterior of the property wasn’t quite what we expected but the inside was very cozy and inviting. Overall would recommend especially if you have a dog that like to run around outside. " [](https://expedia.ca/Santee-Hotels-This-House-Is-A-3-Bedroom.h91788460.Hotel-Information) ![Quality Inn & Suites Santee I-95](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/cd0ca695_y.jpg) ### Quality Inn & Suites Santee I-95 6/10 Okay "Rooms are updated and clean. Very good value for the price of the room. " [](https://expedia.ca/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [5 Star Hotels in Manning ](https://www.expedia.ca/5Star-Manning-Hotels.s50-0-d8454.Travel-Guide-Filter-Hotels) - [Independent Hotels in Blackville ](https://www.expedia.ca/Blackville-Hotels-Independent.0-0-d3000455854--bIndependent.Travel-Guide-Filter-Hotels) - [B&B in Bowman ](https://www.expedia.ca/Bowman-Bed-And-Breakfast.d553248634998681915-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Red Roof Inn Hotels in Bowman ](https://www.expedia.ca/Bowman-Hotels-Red-Roof-Inn.0-0-d553248634998681915--bRedRoofInn.Travel-Guide-Filter-Hotels) - [Bowman Hotels ](https://www.expedia.ca/Bowman-Hotels.d553248634998681915.Travel-Guide-Hotels) - [Apartments in Brookdale ](https://www.expedia.ca/Brookdale-Apartments.d553248634999003908-aaApartments.Travel-Guide-Accommodation) - [Hotels with Free Breakfast in Brookdale ](https://www.expedia.ca/Brookdale-Hotels-Hotels-With-Free-Breakfast.0-0-d553248634999003908-tHotelswithFreeBreakfast.Travel-Guide-Filter-Hotels) - 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