A sunset over a beach with a pier extending into the water.

Find Spa Hotels in Los Osos, CA from CA $290

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Our top choices for Los Osos hotels with a spa

Reception

Cayucos Sunset Inn B&B

Cayucos Sunset Inn B&B
3.5 star property
Cayucos
9.8 out of 10, Exceptional, (245 reviews)
  • cleanliness
    Relax in a beachside inn with private hot tubs, garden views, and rejuvenating couples massages.
The price is CA $361
CA $406 total
includes taxes & fees
Jul 27 - Jul 28
Cayucos Sunset Inn B&B
Caveman | Bathroom

Madonna Inn

Madonna Inn
3.5 star property
San Luis Obispo
9.2 out of 10, Wonderful, (1,512 reviews)
  • cleanliness
    Unwind at a unique spa retreat with six treatment rooms for aromatherapy, body scrubs, and massages in scenic comfort.
The price is CA $311
CA $401 total
includes taxes & fees
Jul 30 - Jul 31
Madonna Inn
Exterior

The Agrarian Hotel, BW Signature Collection

The Agrarian Hotel, BW Signature Collection
2.5 star property
Arroyo Grande
9.6 out of 10, Exceptional, (1,000 reviews)
  • cleanliness
    Revitalize mind and body at this charming hotel with therapeutic spa services and a bubbling hot tub.
The price is CA $255
CA $290 total
includes taxes & fees
Jul 19 - Jul 20
The Agrarian Hotel, BW Signature Collection
Property grounds

Avila La Fonda Hotel

Avila La Fonda Hotel
4.0 star property
Avila Beach
9.6 out of 10, Exceptional, (1,000 reviews)
  • cleanliness
    Revitalizing seaside escape with private indoor hot tubs and spa services offers a wellness retreat just steps from the beach.
The price is CA $378
CA $425 total
includes taxes & fees
Aug 16 - Aug 17
Avila La Fonda Hotel
Lobby

Hotel San Luis Obispo

Hotel San Luis Obispo
4.5 star property
Downtown San Luis Obispo
9.4 out of 10, Exceptional, (622 reviews)
  • cleanliness
    Savour serenity at this luxury hotel with a full-service spa offering daily treatments and couples' massage rooms in San Luis Obispo.
The price is CA $599
CA $679 total
includes taxes & fees
Jul 20 - Jul 21
Hotel San Luis Obispo
Reception

HOTEL CERRO, Autograph Collection

HOTEL CERRO, Autograph Collection
4.0 star property
Downtown San Luis Obispo
9.2 out of 10, Wonderful, (489 reviews)
  • cleanliness
    Tranquil urban retreat with steam room, rooftop garden, and holistic treatments for a restorative wellness escape.
The price is CA $531
CA $651 total
includes taxes & fees
Aug 2 - Aug 3
HOTEL CERRO, Autograph Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Los Osos

Pool
Breakfast included

Top Los Osos Hotel Reviews

Vagabond Inn San Luis Obispo

Vagabond Inn San Luis Obispo

10/10 Excellent
"We were pleasantly surprised at how large the room and the bed was.Plenty of room for 2 adults or family with 2 young children. The bed was very comfortable .the bed cover surprisingly tasteful.the bedside lights handy for readers in bed. The mini fridge worked,the ironing board very helpful AND the tub actually deeper than normal. Lights and air-conditioning worked. Room was very clean,no smells shower good pressure,,it appeared the rooms were recently redone. Yes,,I highly recommend staying here Lots of parking ,3 minutes by car to Main Street. Handy location! Yes,I would return"
jane 1-night trip
Posted 1 hour ago
Vagabond Inn San Luis Obispo

Frequently asked questions

Which hotels in Los Osos offer the best spa experiences?
The best spa experiences in Los Osos can be found at the Sea Pines Resort.

The 3-star Sea Pines Resort, with an 8.2 rating, offers a full-service spa with an extensive treatment menu that includes deep tissue and hot stone massages. The spa features dedicated couples' treatment rooms, providing a serene environment for shared relaxation.
How much does a spa hotel in Los Osos cost?
Enjoy staying in a spa hotel in Los Osos, with plenty of hotels from CA $290 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, and may vary depending on the location, season, and hotel amenities. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a trip during the weekend or around public holidays.
Is it cheaper to book a spa hotel in Los Osos with flights as part of a package deal?
Booking a hotel and flight package on Expedia can be cheaper than booking flights and hotels separately. Bundling can lead to significant savings, especially for international travel or when booking well in advance. However, savings vary depending on factors like destination, travel dates, and availability, so it's wise to compare options. With access to over 300,000 hotels worldwide, Expedia makes it easy to build the perfect travel package.
Are there hotels in Los Osos that offer couples' spa treatments?
For couples seeking spa treatments in Los Osos, the Sea Pines Resort is an excellent option.

This 3-star hotel, with an 8.2 rating, offers couples' treatment rooms, allowing for a shared and intimate spa experience. The full-service spa provides a variety of treatments, including hot stone and deep tissue massages, for which advance notice is recommended.
Are there any unique spa experiences available in Los Osos?
Yes, there are unique spa experiences available near Los Osos, California, particularly centred around mineral springs and holistic treatments.

Sycamore Mineral Springs Resort & Spa, located approximately 10.8 miles from Los Osos, offers a distinctive experience with hot tubs filled with natural mineral spring water, located on a scenic hillside under oak trees. Guests can enjoy soaking in these mineral waters, often accompanied by local wine.

AcuGlo Acupuncture in Los Osos provides a unique blend of ancient Chinese healing and modern beauty techniques, including facial acupuncture, gua sha, facial reflexology, and herbal remedies, offering a wellness experience beyond traditional spa services.

Nearby resorts such as The Cliffs Hotel and Spa and Avila Lighthouse Suites also offer spa packages with massages, facials, and relaxing amenities, providing more conventional spa experiences.
How can I save on a spa hotel in Los Osos with Expedia?
Members always get our best prices. Find our best Los Osos spa hotel deals by joining Expedia's free travel rewards program—One Key™. As a member, you can unlock instant savings and member perks when you're logged in to your account. For a spontaneous weekend retreat, discover last-minute offers.
Can I cancel my spa hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use Expedia's "Fully refundable property" filter during your search to find the right spa hotel in Los Osos for you.

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