Title: Book the Best Los Osos SPA Resorts from CA $215 - Spa Hotels in Los Osos, CA | Expedia.ca [Los Osos Travel Guide](https://expedia.ca/Los-Osos.dx9873)[Hotels in Los Osos](https://expedia.ca/Los-Osos-Hotels.d9873.Travel-Guide-Hotels)[Vacation Rentals in Los Osos](https://expedia.ca/Los-Osos-Vacation-Rentals.d9873.Travel-Guide-VacationRentals)[Flights to Los Osos](https://expedia.ca/Cheap-Flights-To-Los-Osos.d9873.Travel-Guide-Flights)[Los Osos Car Rentals](https://expedia.ca/Car-Rentals-In-Los-Osos.d9873.Car-Rental-Guide)[Los Osos Vacation Packages](https://expedia.ca/Los-Osos.d9873.Destination-Travel-Guides) ![Such a nice place!](https://images.trvl-media.com/place/553248621532639980/2c5ca4d7-c91a-4938-ad4a-7fa3b4914016.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Lisa Travelfeet ![](https://images.trvl-media.com/place/553248621532639980/2c5ca4d7-c91a-4938-ad4a-7fa3b4914016.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Los Osos Spa Hotels Tonight [Jan 17 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=9873&startDate=2026-01-17&endDate=2026-01-18&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 18 - Jan 19](https://www.expedia.ca/Hotel-Search?regionId=9873&startDate=2026-01-18&endDate=2026-01-19&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=9873&startDate=2026-01-23&endDate=2026-01-25&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=9873&startDate=2026-01-30&endDate=2026-02-01&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Los Osos hotels with a spa ![Caveman | Bathroom](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/29ce234c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, individually decorated](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/63206dec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/1ea42b7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Madonna Suite | Bathroom](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/a4e68773.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Madonna Inn [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Madonna-Inn.h1190976.Hotel-Information) San Luis Obispo 9.2/10 Wonderful (1,356 reviews) "Breakfast & views were amazing! Loved this place!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nick CA $201 CA $276 total includes taxes & fees Jan 19 - Jan 20 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Madonna-Inn.h1190976.Hotel-Information) ![Staircase](https://images.trvl-media.com/lodging/2000000/1180000/1178000/1177942/6f4e12c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Room, 2 Queen Beds](https://images.trvl-media.com/lodging/2000000/1180000/1178000/1177942/a1ad61d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach nearby](https://images.trvl-media.com/lodging/2000000/1180000/1178000/1177942/a9f0fa5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed | Terrace/patio](https://images.trvl-media.com/lodging/2000000/1180000/1178000/1177942/1d45972a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Avila Village Inn [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Avila-Village-Inn.h1177942.Hotel-Information) Avila Beach 9.2/10 Wonderful (1,000 reviews) "I loved the place - it was classy and homey at the same time. It had a trail leading to the town from the hotel, so charming! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christina [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Avila-Village-Inn.h1177942.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/dea8ddbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/bd2697e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/f7fb843a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/1d10b621.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Agrarian Hotel, BW Signature Collection [](https://www.expedia.ca/San-Luis-Obispo-Hotels-The-Agrarian-Hotel.h36117545.Hotel-Information) Arroyo Grande 9.6/10 Exceptional (1,005 reviews) "Very nice place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chritine CA $189 CA $215 total includes taxes & fees Jan 19 - Jan 20 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-The-Agrarian-Hotel.h36117545.Hotel-Information) ![Exclusive Suite, Private Bathroom (PREMIER CALIFORNIA KING - Bay View)](https://images.trvl-media.com/lodging/117000000/116800000/116793800/116793728/e10d36bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, Private Bathroom (QUEEN BED - Town View) | Beach/ocean view](https://images.trvl-media.com/lodging/117000000/116800000/116793800/116793728/207f33e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Soundproofing, free WiFi, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/117000000/116800000/116793800/116793728/70d6de9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Soundproofing, free WiFi, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/117000000/116800000/116793800/116793728/95bde690.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Inn at Rose's Landing [](https://www.expedia.ca/Morro-Bay-Hotels-Inn-At-Roses-Landing.h116793728.Hotel-Information) Downtown Morro Bay 9.0/10 Wonderful (2 reviews) "Central location Easy parking Clean, newly remodeled room with extensive range of amenities available Staff was extremely friendly and helpful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Emily CA $291 CA $333 total includes taxes & fees Jan 19 - Jan 20 [](https://www.expedia.ca/Morro-Bay-Hotels-Inn-At-Roses-Landing.h116793728.Hotel-Information) ![Coffee service](https://images.trvl-media.com/lodging/36000000/35830000/35826200/35826166/d2bd3038.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/36000000/35830000/35826200/35826166/3dde3a99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Honeymoon Suite, 1 King Bed, Non Smoking, Ocean View](https://images.trvl-media.com/lodging/36000000/35830000/35826200/35826166/8e1a2a5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/36000000/35830000/35826200/35826166/10b1b07e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cayucos Sunset Inn B&B [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Cayucos-Sunset-Inn-Bed-And-Breakfast.h35826166.Hotel-Information) Cayucos 9.8/10 Exceptional (200 reviews) "Very nice accommodations, staff extremely friendly!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jacqueline CA $245 CA $276 total includes taxes & fees Jan 19 - Jan 20 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Cayucos-Sunset-Inn-Bed-And-Breakfast.h35826166.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/2000000/1510000/1507200/1507108/c2c4905d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1510000/1507200/1507108/74e3dfcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Owners Suite | Living area](https://images.trvl-media.com/lodging/2000000/1510000/1507200/1507108/86271dbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, pillowtop beds](https://images.trvl-media.com/lodging/2000000/1510000/1507200/1507108/1386e090.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Avila La Fonda Hotel [](https://www.expedia.ca/Avila-Beach-Hotels-Avila-La-Fonda-Hotel.h1507108.Hotel-Information) Avila Beach 9.6/10 Exceptional (1,002 reviews) "From the moment at check-in staff was awesome and the accommodations were great. Great quiet little cali beach town. La Fonda is the right place to stay. One block from the beach as well. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeff CA $252 CA $284 total includes taxes & fees Feb 16 - Feb 17 [](https://www.expedia.ca/Avila-Beach-Hotels-Avila-La-Fonda-Hotel.h1507108.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/42ac20df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/e0c265d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/22fcbd4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/8a3ff3f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOTEL CERRO, Autograph Collection [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hotel-Cerro.h48257614.Hotel-Information) Downtown San Luis Obispo 9.2/10 Wonderful (472 reviews) "Staff is horrible and I was charged by Expedia and also the hotel and they’re refusing to refund me " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Demeishia CA $330 CA $422 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hotel-Cerro.h48257614.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/088fc1a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Morro Suite | Living area](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/96137871.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/3f29ecb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/bdb8f309.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel San Luis Obispo [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hotel-San-Luis-Obispo.h37232966.Hotel-Information) Downtown San Luis Obispo 9.4/10 Exceptional (571 reviews) "Friendly staff lovely room and nice amenities " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anthony CA $512 CA $581 total includes taxes & fees Jan 23 - Jan 24 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hotel-San-Luis-Obispo.h37232966.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-01&endDate=2026-02-02®ionId=9873&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Los Osos Hotel Reviews ![Embassy Suites by Hilton San Luis Obispo](https://images.trvl-media.com/lodging/1000000/20000/15500/15406/48c2929b_y.jpg) ### Embassy Suites by Hilton San Luis Obispo 10/10 Excellent "The room was very clean but for me what stood out the most was the staff. They were very helpful, Very Friendly and took the time to answer all questions." [](https://expedia.ca/San-Luis-Obispo-Hotels-Embassy-Suites-By-Hilton-San-Luis-Obispo.h15406.Hotel-Information) ![Quality Suites Downtown San Luis Obispo](https://images.trvl-media.com/lodging/1000000/10000/3200/3138/9ac45291_y.jpg) ### Quality Suites Downtown San Luis Obispo 10/10 Excellent "VERY nice property and resort fees waived for Expedia clients." [](https://expedia.ca/San-Luis-Obispo-Hotels-Quality-Suites-Downtown-San-Luis-Obispo.h3138.Hotel-Information) ![Sandcastle Hotel on the Beach](https://images.trvl-media.com/lodging/1000000/50000/41000/40915/89d1e3f1_y.jpg) ### Sandcastle Hotel on the Beach 10/10 Excellent "Very clean. Right on the beach. " [](https://expedia.ca/San-Luis-Obispo-Hotels-Sandcastle-Hotel-On-The-Beach.h40915.Hotel-Information) ![Spyglass Inn](https://images.trvl-media.com/lodging/1000000/50000/41300/41235/44c3350f_y.jpg) ### Spyglass Inn 10/10 Excellent "Communal fire pits. Private fireplace. Oceanfront walking access. " [](https://expedia.ca/San-Luis-Obispo-Hotels-Spyglass-Inn.h41235.Hotel-Information) ![Cottage Inn By The Sea](https://images.trvl-media.com/lodging/1000000/160000/151000/150921/c54d7346_y.jpg) ### Cottage Inn By The Sea 10/10 Excellent "Cute little stay with my partner. Would happily return again for the ocean view and that exceptionally cozy fireplace!" [](https://expedia.ca/San-Luis-Obispo-Hotels-Cottage-Inn-By-The-Sea.h150921.Hotel-Information) ![Oxford Suites Pismo Beach](https://images.trvl-media.com/lodging/1000000/10000/3100/3089/b427747a_y.jpg) ### Oxford Suites Pismo Beach 10/10 Excellent "Great experience " [](https://expedia.ca/San-Luis-Obispo-Hotels-Oxford-Suites-Pismo-Beach.h3089.Hotel-Information) ![Apple Farm](https://images.trvl-media.com/lodging/1000000/40000/39500/39435/f5438f41_y.jpg) ### Apple Farm 10/10 Excellent "Best hotel value for the price. I like my nice hotels and nothing else in SLO compares for proximity to town, walkable, great breakfast and clean and cozy rooms. My last room had a deck with patio lights! " [](https://expedia.ca/San-Luis-Obispo-Hotels-Apple-Farm.h39435.Hotel-Information) ![Madonna Inn](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/1ea42b7b_y.jpg) ### Madonna Inn 10/10 Excellent "Love the quirky theme rooms. Came for a wedding and it was gorgeous! Great restaurants and bar. Lovely grounds and pool." [](https://expedia.ca/San-Luis-Obispo-Hotels-Madonna-Inn.h1190976.Hotel-Information) ![Edgewater Inn And Suites](https://images.trvl-media.com/lodging/1000000/900000/894000/893902/3d1c5694_y.jpg) ### Edgewater Inn And Suites 10/10 Excellent "It was awesome to stay here " [](https://expedia.ca/San-Luis-Obispo-Hotels-Edgewater-Inn-And-Suites.h893902.Hotel-Information) ## Frequently asked questions ### Which hotels in Los Osos offer the best spa experiences? > The 3-star Sea Pines Resort, with an 8.2 rating, offers a full-service spa with an extensive treatment menu that includes deep tissue and hot stone massages. The spa features dedicated couples' treatment rooms, providing a serene environment for shared relaxation. ### How much does a spa hotel in Los Osos cost? ### Is it cheaper to book a spa hotel in Los Osos with flights as part of a package deal? ### Are there hotels in Los Osos that offer couples' spa treatments? > This 3-star hotel, with an 8.2 rating, offers couples' treatment rooms, allowing for a shared and intimate spa experience. The full-service spa provides a variety of treatments, including hot stone and deep tissue massages, for which advance notice is recommended. ### Are there any unique spa experiences available in Los Osos? > Sycamore Mineral Springs Resort & Spa, located approximately 10.8 miles from Los Osos, offers a distinctive experience with hot tubs filled with natural mineral spring water, located on a scenic hillside under oak trees. Guests can enjoy soaking in these mineral waters, often accompanied by local wine. > > > AcuGlo Acupuncture in Los Osos provides a unique blend of ancient Chinese healing and modern beauty techniques, including facial acupuncture, gua sha, facial reflexology, and herbal remedies, offering a wellness experience beyond traditional spa services. > > > Nearby resorts such as The Cliffs Hotel and Spa and Avila Lighthouse Suites also offer spa packages with massages, facials, and relaxing amenities, providing more conventional spa experiences. ### How can I save on a spa hotel in Los Osos with Expedia? ### Can I cancel my spa hotel reservation on Expedia? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [3 Star Hotels in Morro Bay ](https://www.expedia.ca/3Star-Morro-Bay-Hotels.s30-0-d8976.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Morro Bay ](https://www.expedia.ca/5Star-Morro-Bay-Hotels.s50-0-d8976.Travel-Guide-Filter-Hotels) - 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