Title: Book the Best Los Osos SPA Resorts from CA $214 - Spa Hotels in Los Osos, CA | Expedia.ca [Los Osos Travel Guide](https://expedia.ca/Los-Osos.dx9873)[Hotels in Los Osos](https://expedia.ca/Los-Osos-Hotels.d9873.Travel-Guide-Hotels)[Vacation Rentals in Los Osos](https://expedia.ca/Los-Osos-Vacation-Rentals.d9873.Travel-Guide-VacationRentals)[Flights to Los Osos](https://expedia.ca/Cheap-Flights-To-Los-Osos.d9873.Travel-Guide-Flights)[Los Osos Car Rentals](https://expedia.ca/Car-Rentals-In-Los-Osos.d9873.Car-Rental-Guide)[Los Osos Vacation Packages](https://expedia.ca/Los-Osos.d9873.Destination-Travel-Guides) ![Such a nice place!](https://images.trvl-media.com/place/553248621532639980/2c5ca4d7-c91a-4938-ad4a-7fa3b4914016.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Lisa Travelfeet # Find Spa Hotels in Los Osos, CA from CA $214 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Los Osos Spa Hotels Tonight [Dec 3 - Dec 4](https://www.expedia.ca/Hotel-Search?regionId=9873&startDate=2025-12-03&endDate=2025-12-04&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 4 - Dec 5](https://www.expedia.ca/Hotel-Search?regionId=9873&startDate=2025-12-04&endDate=2025-12-05&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=9873&startDate=2025-12-05&endDate=2025-12-07&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=9873&startDate=2025-12-12&endDate=2025-12-14&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Los Osos Spa Hotels ![Property entrance](https://images.trvl-media.com/lodging/2000000/1180000/1178000/1177942/eb1d5a6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed | Terrace/patio](https://images.trvl-media.com/lodging/2000000/1180000/1178000/1177942/1d45972a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/2000000/1180000/1178000/1177942/be8d8cf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Room, 2 Queen Beds](https://images.trvl-media.com/lodging/2000000/1180000/1178000/1177942/a1ad61d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Avila Village Inn Avila Beach 9.2/10 Wonderful (1000) "The property and rooms were beautiful! We really enjoyed our weekend here and are planning to stay again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cathy [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Avila-Village-Inn.h1177942.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/9e66f2c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/323aabf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/4e72b30d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/1d10b621.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Agrarian Hotel, BW Signature Collection Arroyo Grande 9.6/10 Exceptional (1017) "The room was super comfortable and clean. They offered a great breakfast too!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) kim CA $188 CA $214 total includes taxes & fees Dec 4 - Dec 5 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-The-Agrarian-Hotel.h36117545.Hotel-Information) ![Caveman | Bathroom](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/29ce234c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/d6246a9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Highway Suite](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/59b09fa5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/5a091377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Madonna Inn San Luis Obispo 9.2/10 Wonderful (1313) "Fun place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kyle CA $208 CA $284 total includes taxes & fees Dec 4 - Dec 5 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Madonna-Inn.h1190976.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1840000/1839900/1839838/09f8fafa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1840000/1839900/1839838/811c4b37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Single Room, 2 Queen Beds | Exterior](https://images.trvl-media.com/lodging/2000000/1840000/1839900/1839838/6a62dfc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor wedding area](https://images.trvl-media.com/lodging/2000000/1840000/1839900/1839838/af3dfd64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sea Pines Resort Los Osos 8.2/10 Very good (410) "Nice staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ann [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Sea-Pines-Resort.h1839838.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/36000000/35830000/35826200/35826166/46c8343c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/36000000/35830000/35826200/35826166/57423573.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Honeymoon Suite, 1 King Bed, Non Smoking, Ocean View](https://images.trvl-media.com/lodging/36000000/35830000/35826200/35826166/8e1a2a5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/36000000/35830000/35826200/35826166/10b1b07e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cayucos Sunset Inn B&B Cayucos 9.8/10 Exceptional (194) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jason CA $244 CA $274 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Cayucos-Sunset-Inn-Bed-And-Breakfast.h35826166.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/42ac20df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/41f2d375.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/18ffa136.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/dd32277b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOTEL CERRO, Autograph Collection Downtown San Luis Obispo 9.2/10 Wonderful (466) "We had a great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ADALBERT CA $272 CA $357 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hotel-Cerro.h48257614.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/2000000/1510000/1507200/1507108/c2c4905d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gift shop](https://images.trvl-media.com/lodging/2000000/1510000/1507200/1507108/5276bae4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/2000000/1510000/1507200/1507108/cd3bd54d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Room, 1 King Bed (Spa Room) | Library](https://images.trvl-media.com/lodging/2000000/1510000/1507200/1507108/2d3891c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Avila La Fonda Hotel Avila Beach 9.6/10 Exceptional (1000) "Very nice hotel. Great for and rest and relaxation kind of vacation" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Princess CA $259 CA $292 total includes taxes & fees Dec 9 - Dec 10 [](https://www.expedia.ca/Avila-Beach-Hotels-Avila-La-Fonda-Hotel.h1507108.Hotel-Information) ![Morro Suite | Living area](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/96137871.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Tolosa Terrace King](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/cdd4facb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Paseo King Room](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/0c2ec67b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/b4e2ccc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel San Luis Obispo Downtown San Luis Obispo 9.4/10 Exceptional (543) "Beautiful room and nice rooftop bar!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chizuru CA $414 CA $469 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hotel-San-Luis-Obispo.h37232966.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-17&endDate=2025-12-18®ionId=9873&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_CA_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Limited-time deals: save up to 50% on select hotels [Book now](https://expedia.ca/deals?rfrr=AFFINITY_BF_PROMO_9873) ## Top Los Osos Hotel Reviews ![Cottage Inn By The Sea](https://images.trvl-media.com/lodging/1000000/160000/151000/150921/c54d7346_y.jpg) ### Cottage Inn By The Sea 10/10 Excellent "We always stay at the Cottage Inn. The staff is awesome and the property is amazing." [](https://expedia.ca/San-Luis-Obispo-Hotels-Cottage-Inn-By-The-Sea.h150921.Hotel-Information) ![Oxford Suites Pismo Beach](https://images.trvl-media.com/lodging/1000000/10000/3100/3089/b427747a_y.jpg) ### Oxford Suites Pismo Beach 10/10 Excellent "Clean room " [](https://expedia.ca/San-Luis-Obispo-Hotels-Oxford-Suites-Pismo-Beach.h3089.Hotel-Information) ![SeaCrest OceanFront Hotel](https://images.trvl-media.com/lodging/2000000/1370000/1365400/1365352/w3000h1999x0y0-15b2e131_y.jpg) ### SeaCrest OceanFront Hotel 10/10 Excellent "Our room had a large balcony and from it during daylight hours we could see the ocean. The hotel is on a bluff but has stairs where guests can walk down to Pismo Beach and walk for miles on the pristine sand and then on the Boardwalk. You can also walk to the cute shops and onto the Pismo Pier. The pier has a Christmas tree lit up at night that you can see from the hotel." [](https://expedia.ca/San-Luis-Obispo-Hotels-SeaCrest-OceanFront-Hotel.h1365352.Hotel-Information) ![Inn at the Cove](https://images.trvl-media.com/lodging/1000000/20000/15400/15382/b6db59c4_y.jpg) ### Inn at the Cove 10/10 Excellent "Ex" [](https://expedia.ca/San-Luis-Obispo-Hotels-Inn-At-The-Cove.h15382.Hotel-Information) ![Apple Farm](https://images.trvl-media.com/lodging/1000000/40000/39500/39435/f5438f41_y.jpg) ### Apple Farm 10/10 Excellent "The room was perfect, clean quaint very cute. The staff was kind and always helpful and the grounds are just beautiful super great place to stay." [](https://expedia.ca/San-Luis-Obispo-Hotels-Apple-Farm.h39435.Hotel-Information) ![Shore Cliff Hotel](https://images.trvl-media.com/lodging/1000000/10000/9800/9742/ff9d613b_y.jpg) ### Shore Cliff Hotel 10/10 Excellent "Clean room, amenities inluding the beach supplies for the kids were awesome! We had great stay. " [](https://expedia.ca/San-Luis-Obispo-Hotels-Shore-Cliff-Hotel.h9742.Hotel-Information) ![Sandcastle Hotel on the Beach](https://images.trvl-media.com/lodging/1000000/50000/41000/40915/89d1e3f1_y.jpg) ### Sandcastle Hotel on the Beach 10/10 Excellent "Location is excellent and the staff were kind. " [](https://expedia.ca/San-Luis-Obispo-Hotels-Sandcastle-Hotel-On-The-Beach.h40915.Hotel-Information) ![Embassy Suites by Hilton San Luis Obispo](https://images.trvl-media.com/lodging/1000000/20000/15500/15406/48c2929b_y.jpg) ### Embassy Suites by Hilton San Luis Obispo 10/10 Excellent "Spacious and comfortable. The room was clean and the beds were very comfortable. My 10 yr old grandson slept on the sectional couch, which he claims was the most comfortable couch he’s ever been on. It was large and fit all 5 of us when seated. I will most definitely stay here again. " [](https://expedia.ca/San-Luis-Obispo-Hotels-Embassy-Suites-By-Hilton-San-Luis-Obispo.h15406.Hotel-Information) ![La Cuesta Inn, BW Signature Collection](https://images.trvl-media.com/lodging/1000000/20000/14400/14372/f5b74a44_y.jpg) ### La Cuesta Inn, BW Signature Collection 10/10 Excellent "Friendly staff and comfy bed" [](https://expedia.ca/San-Luis-Obispo-Hotels-La-Cuesta-Inn.h14372.Hotel-Information) ## Frequently asked questions ### Looking for a spa hotel in Los Osos? > Forget the stress of everyday life and book yourself a hotel with a spa. Check out the beaches in Los Osos - worth a picture or two! Take part in recreational activities such as golfing during your vacation. Hotels with spas are a great way to break away from your daily routine and add a layer of luxury to your vacation. ### What is the best spa hotel in Los Osos? > [Sea Pines Resort](https://www.expedia.ca/San-Luis-Obispo-Hotels-Sea-Pines-Resort.h1839838.Hotel-Information) is a top spa hotel featuring a golf course, a bar, and a restaurant. Spend an afternoon at the spa where you'll find deep-tissue massages, hot stone massages, and couples treatments. ### How many spa hotels will I find in Los Osos? > Among Expedia's 45 accommodation options in Los Osos, there is 1 spa hotel. ### What's there to see and do in Los Osos? > Experience Los Osos with a stop at Los Osos Oaks State Reserve, Elfin Forest Preserve, and Montaña de Oro State Park. If you have a bit of extra time while you're in the area, you might want to check out Morro Bay State Park and Morro Coast Audubon Society Sweet Springs Nature Preserve. ### What is a Los Osos spa hotel? > Spa hotels in Los Osos provide lodging and have an on-site spa which offers services such as facials as well as body treatments. Some also offer in-room treatments. 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