Book the Best Los Osos SPA Resorts from CA $240 - Spa Hotels in Los Osos, CA

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Our top choices for Los Osos hotels with a spa

Madonna Inn

San Luis Obispo

Unwind at a unique spa retreat with six treatment rooms for aromatherapy, body scrubs, and massages in scenic comfort.

CA $311 total

includes taxes & fees

Jun 10 - Jun 11

Cayucos Sunset Inn B&B

Cayucos

Relax in a beachside inn with private hot tubs, garden views, and rejuvenating couples massages.

CA $277 total

includes taxes & fees

Jun 15 - Jun 16

The Agrarian Hotel, BW Signature Collection

Arroyo Grande

Revitalize mind and body at this charming hotel with therapeutic spa services and a bubbling hot tub.

CA $240 total

includes taxes & fees

Jun 11 - Jun 12

Avila La Fonda Hotel

Avila Beach

Revitalizing seaside escape with private indoor hot tubs and spa services offers a wellness retreat just steps from the beach.

CA $422 total

includes taxes & fees

Jun 30 - Jul 1

Hotel San Luis Obispo

Downtown San Luis Obispo

Savour serenity at this luxury hotel with a full-service spa offering daily treatments and couples' massage rooms in San Luis Obispo.

CA $672 total

includes taxes & fees

Jun 10 - Jun 11

HOTEL CERRO, Autograph Collection

Downtown San Luis Obispo

Tranquil urban retreat with steam room, rooftop garden, and holistic treatments for a restorative wellness escape.

CA $604 total

includes taxes & fees

Jun 15 - Jun 16

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Choose what matters most at spa hotels in Los Osos

Pool

Breakfast included

Top Los Osos Hotel Reviews

SeaCrest OceanFront Hotel

10/10 Excellent

"Great service clean wonderful breakfast bar the sea crest goes the extra mile puts out cookies in the afternoon for the guests a bar right outside the pool family friendly pool and two hot tubs and still had an extra hot tub adults only private area great fire pit seating for the morning and evenings ! Beautiful views and close access to the beach"

Madonna Inn

10/10 Excellent

"A huge property with different themed rooms. Quite unique. The pool bar attendant was unhelpful and disappeared when we wanted to order drinks. He also refused to make a reservation for us for the restaurant. The bar/cafe area was lovely. The staff were helpful and the food was reasonable and delicious. The main dining area had a 12 piece old style dance band that lended well to the overall decor and atmosphere. Although registration, who were pleasant and helpful, offered to have a porter help us with the luggage, as a nearly 80 yo, I landed up carrying heavy cases up 3 levels of stairs. Not good! Overall the experience was wonderful."