Title: Book the Best Los Osos SPA Resorts from CA $239 - Spa Hotels in Los Osos, CA | Expedia.ca [Los Osos Travel Guide](https://expedia.ca/Los-Osos.dx9873)[Hotels in Los Osos](https://expedia.ca/Los-Osos-Hotels.d9873.Travel-Guide-Hotels)[Vacation Rentals in Los Osos](https://expedia.ca/Los-Osos-Vacation-Rentals.d9873.Travel-Guide-VacationRentals)[Flights to Los Osos](https://expedia.ca/Cheap-Flights-To-Los-Osos.d9873.Travel-Guide-Flights)[Los Osos Car Rentals](https://expedia.ca/Car-Rentals-In-Los-Osos.d9873.Car-Rental-Guide)[Los Osos Vacation Packages](https://expedia.ca/Los-Osos.d9873.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/82ae60cf1761badedca5aae03e4e0866.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Los Osos, CA from CA $239 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Los Osos Spa Hotels Tonight [Sep 24 - Sep 25](https://www.expedia.ca/Hotel-Search?regionId=9873&startDate=2025-09-24&endDate=2025-09-25&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 25 - Sep 26](https://www.expedia.ca/Hotel-Search?regionId=9873&startDate=2025-09-25&endDate=2025-09-26&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=9873&startDate=2025-09-26&endDate=2025-09-28&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=9873&startDate=2025-10-03&endDate=2025-10-05&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Los Osos Spa Hotels ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1840000/1839900/1839838/09f8fafa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Single Room, 2 Queen Beds | Exterior](https://images.trvl-media.com/lodging/2000000/1840000/1839900/1839838/6a62dfc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1840000/1839900/1839838/811c4b37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/2000000/1840000/1839900/1839838/4adefcff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sea Pines Resort Los Osos 8.2/10 Very good (402) "All around an amazing place to stay." CA $187 CA $242 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Sea-Pines-Resort.h1839838.Hotel-Information) ![Caveman | Bathroom](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/29ce234c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/5a091377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed | Terrace/patio](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/01a54722.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Highway Suite](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/59b09fa5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Madonna Inn San Luis Obispo 9.2/10 Wonderful (1246) "Always a great stay! Staff is always nice and gift shops are great. We love the Madonna Inn!" CA $204 CA $279 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Madonna-Inn.h1190976.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/9e66f2c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/1d10b621.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/323aabf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/4e72b30d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Agrarian Hotel, BW Signature Collection Arroyo Grande 9.6/10 Exceptional (1011) "Great location" CA $211 CA $239 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-The-Agrarian-Hotel.h36117545.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/42ac20df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/18ffa136.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/dd32277b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/786b3840.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOTEL CERRO, Autograph Collection Downtown San Luis Obispo 9.2/10 Wonderful (459) "We had a great stay" CA $280 CA $365 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hotel-Cerro.h48257614.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/2000000/1510000/1507200/1507108/c2c4905d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/2000000/1510000/1507200/1507108/cd3bd54d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gift shop](https://images.trvl-media.com/lodging/2000000/1510000/1507200/1507108/5276bae4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Double Room (Great Room) | Room amenity](https://images.trvl-media.com/lodging/2000000/1510000/1507200/1507108/5728603e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Avila La Fonda Hotel Avila Beach 9.6/10 Exceptional (1003) "Fantastic stay with a great location and food options!" CA $257 CA $290 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/Avila-Beach-Hotels-Avila-La-Fonda-Hotel.h1507108.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/36000000/35830000/35826200/35826166/46c8343c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/36000000/35830000/35826200/35826166/57423573.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/36000000/35830000/35826200/35826166/d2bd3038.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/36000000/35830000/35826200/35826166/10b1b07e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cayucos Sunset Inn B&B Cayucos 9.8/10 Exceptional (189) "Great place to stay" CA $273 CA $307 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Cayucos-Sunset-Inn-Bed-And-Breakfast.h35826166.Hotel-Information) ![Deluxe Studio Suite](https://images.trvl-media.com/lodging/3000000/2990000/2984500/2984429/8a746193.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/3000000/2990000/2984500/2984429/65367cdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/3000000/2990000/2984500/2984429/e4b8df1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV, fireplace](https://images.trvl-media.com/lodging/3000000/2990000/2984500/2984429/389e8e53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Creekside Inn of Paso Robles Paso Robles 9.2/10 Wonderful (300) "Enjoyed the complementary bottle of wine & really enjoyed our stay! We would definitely stay here again " CA $304 CA $336 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Creekside-Inn-Of-Paso-Robles.h2984429.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/f3abfe0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/088fc1a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/88590a9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Paseo King Room](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/0c2ec67b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel San Luis Obispo Downtown San Luis Obispo 9.6/10 Exceptional (527) "Great location. " CA $474 CA $538 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hotel-San-Luis-Obispo.h37232966.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-09&endDate=2025-10-10®ionId=9873&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Los Osos Hotel Reviews ![Cottage Inn By The Sea](//images.trvl-media.com/lodging/1000000/160000/151000/150921/76ac3c06_y.jpg) ### Cottage Inn By The Sea 10/10 Excellent "I have stayed here before. I like the look, it’s comfortable. Now days everyone is going so clean modern it feels cold. The staff was all great. Had great suggestions. I was bringing my daughter back to CalPoly. I love that it is right on the beach and we can walk to our favorite breakfast spot, moonlight cafe. I just love the location. " [](https://expedia.ca/San-Luis-Obispo-Hotels-Cottage-Inn-By-The-Sea.h150921.Hotel-Information) ![La Cuesta Inn, BW Signature Collection](//images.trvl-media.com/lodging/1000000/20000/14400/14372/f5b74a44_y.jpg) ### La Cuesta Inn, BW Signature Collection 10/10 Excellent "Absolutely amazing property. Large room and bathroom, super clean and comfortable. Also, loved the balcony. Dog friendly, too!. We’ll be back! 100% Recommend! " [](https://expedia.ca/San-Luis-Obispo-Hotels-La-Cuesta-Inn.h14372.Hotel-Information) ![Sandcastle Hotel on the Beach](//images.trvl-media.com/lodging/1000000/50000/41000/40915/89d1e3f1_y.jpg) ### Sandcastle Hotel on the Beach 10/10 Excellent "The Sandcastle was a great place to stay, right on the beach. We'll be back !" [](https://expedia.ca/San-Luis-Obispo-Hotels-Sandcastle-Hotel-On-The-Beach.h40915.Hotel-Information) ![SeaCrest OceanFront Hotel](//images.trvl-media.com/lodging/2000000/1370000/1365400/1365352/w3000h1999x0y0-15b2e131_y.jpg) ### SeaCrest OceanFront Hotel 10/10 Excellent "Incredible beach view and access, comfortable, quiet, safe area, easy parking, breakfast and amenities all wonderful. Slept so well, i woke up refreshed and ready to tackle the day! " [](https://expedia.ca/San-Luis-Obispo-Hotels-SeaCrest-OceanFront-Hotel.h1365352.Hotel-Information) ![Madonna Inn](//images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/1ea42b7b_y.jpg) ### Madonna Inn 10/10 Excellent "We loved the Madonna Inn. Such a cool, charming hotel. The decor was crazy and so much fun. The pool was exquisite. Food was so so but the service was really grea. " [](https://expedia.ca/San-Luis-Obispo-Hotels-Madonna-Inn.h1190976.Hotel-Information) ![Edgewater Inn And Suites](//images.trvl-media.com/lodging/1000000/900000/894000/893902/3d1c5694_y.jpg) ### Edgewater Inn And Suites 10/10 Excellent "The place was awesome, great location, beautiful views, great staff, spacious room, plenty of parking, loved that it was air conditioned. Since the area was so well lit up at night the amount of light that came through the curtains was a lot, having said that i would recommend this hotel over and over again. We will definitely be back." [](https://expedia.ca/San-Luis-Obispo-Hotels-Edgewater-Inn-And-Suites.h893902.Hotel-Information) ![Quality Suites Downtown San Luis Obispo](//images.trvl-media.com/lodging/1000000/10000/3200/3138/9ac45291_y.jpg) ### Quality Suites Downtown San Luis Obispo 10/10 Excellent "It was a lovely place to stay at." [](https://expedia.ca/San-Luis-Obispo-Hotels-Quality-Suites-Downtown-San-Luis-Obispo.h3138.Hotel-Information) ![Oxford Suites Pismo Beach](//images.trvl-media.com/lodging/1000000/10000/3100/3089/b427747a_y.jpg) ### Oxford Suites Pismo Beach 10/10 Excellent "Hospitable staff, clean property quiet" [](https://expedia.ca/San-Luis-Obispo-Hotels-Oxford-Suites-Pismo-Beach.h3089.Hotel-Information) ![Apple Farm](//images.trvl-media.com/lodging/1000000/40000/39500/39435/f5438f41_y.jpg) ### Apple Farm 10/10 Excellent "Clean and quiet room. Friendly staff." [](https://expedia.ca/San-Luis-Obispo-Hotels-Apple-Farm.h39435.Hotel-Information) ## Frequently asked questions ### Looking for a spa hotel in Los Osos? > Forget the stress of everyday life and book yourself a hotel with a spa. Check out the beaches in Los Osos - worth a picture or two! Take part in recreational activities such as golfing during your vacation. Hotels with spas are a great way to break away from your daily routine and add a layer of luxury to your vacation. ### What is the best spa hotel in Los Osos? > [Sea Pines Resort](https://www.expedia.ca/San-Luis-Obispo-Hotels-Sea-Pines-Resort.h1839838.Hotel-Information) is a top spa hotel featuring a golf course, a bar, and a restaurant. Spend an afternoon at the spa where you'll find deep-tissue massages, hot stone massages, and couples treatments. ### How many spa hotels will I find in Los Osos? > Among Expedia's 46 accommodation options in Los Osos, there is 1 spa hotel. ### What's there to see and do in Los Osos? > Experience Los Osos with a stop at Elfin Forest Preserve, Montaña de Oro State Park, and Morro Bay State Park. If you have a bit of extra time while you're in the area, you might want to check out Los Osos Oaks State Reserve and Morro Coast Audubon Society Sweet Springs Nature Preserve. ### What is a Los Osos spa hotel? > Spa hotels in Los Osos provide lodging and have an on-site spa which offers services such as facials as well as body treatments. Some also offer in-room treatments. 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