Title: The 10 Best Hotels Near Looe Key National Marine Sanctuary, from CA $188 | Expedia.ca [United States of America Travel Guide](https://expedia.ca/United-States-Of-America.dx201)[Vacation Rentals in United States of America](https://expedia.ca/Destinations-In-United-States-Of-America.d201.Vacation-Rental-Destinations)[Flights to United States of America](https://expedia.ca/Destinations-In-United-States-Of-America.d201.Flight-Destinations)[Looe Key National Marine Sanctuary Car Rentals](https://expedia.ca/Car-Rentals-In-Looe-Key-National-Marine-Sanctuary.d553248621533115813.Car-Rental-Guide)[Looe Key National Marine Sanctuary Vacations](https://expedia.ca/Looe-Key-National-Marine-Sanctuary-United-States-Of-America.d553248621533115813.Vacation-Attraction) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels near Looe Key National Marine Sanctuary, from CA $188 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 18 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248621533115813&startDate=2025-10-18&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 19 - Oct 20](https://www.expedia.ca/Hotel-Search?regionId=553248621533115813&startDate=2025-10-19&endDate=2025-10-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248621533115813&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248621533115813&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Top Hotels Close to Looe Key National Marine Sanctuary ![Suite, 1 Bedroom, Kitchen, Sea Facing | Beach/ocean view](https://images.trvl-media.com/lodging/6000000/5570000/5561500/5561465/6492712a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dock](https://images.trvl-media.com/lodging/6000000/5570000/5561500/5561465/a69616f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/6000000/5570000/5561500/5561465/9585f19f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/6000000/5570000/5561500/5561465/0a8ded52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Parmer's Resort 14.1 km from Looe Key National Marine Sanctuary 9.0/10 Wonderful (1003) "Excellent laid back property. Close to a good restaurant " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jane CA $156 CA $222 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Little-Torch-Key-Hotels-Parmers-Resort.h5561465.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/90000000/89720000/89711600/89711513/50f5ab62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Toaster](https://images.trvl-media.com/lodging/90000000/89720000/89711600/89711513/c9f2ce52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Townhome](https://images.trvl-media.com/lodging/90000000/89720000/89711600/89711513/f6c4f83d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Toaster](https://images.trvl-media.com/lodging/90000000/89720000/89711600/89711513/dfdaae4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Little Torch Cottages 13.3 km from Looe Key National Marine Sanctuary 9.2/10 Wonderful (9) "Felt like home. We'd stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William CA $511 CA $890 total includes taxes & fees Oct 23 - Oct 24 [](https://www.expedia.ca/Little-Torch-Key-Hotels-Little-Torch-Cottages.h89711513.Hotel-Information) ![2 Bedroom Aqua Lodge # 13 Barracuda | Living area](https://images.trvl-media.com/lodging/18000000/17110000/17102400/17102343/92962431.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17110000/17102400/17102343/1bf38821.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 Bedroom Aqualodge # 6 Tarpon | Living area](https://images.trvl-media.com/lodging/18000000/17110000/17102400/17102343/dee083de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 8:30 AM to 8:00 PM, sun loungers](https://images.trvl-media.com/lodging/18000000/17110000/17102400/17102343/bdbf7145.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Old Wooden Bridge Resort and Marina 17.6 km from Looe Key National Marine Sanctuary 8.6/10 Excellent (260) "I love this place!!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Greg CA $124 CA $337 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Big-Pine-Key-Hotels-Old-Wooden-Bridge-Marina.h17102343.Hotel-Information) ![Flat-screen TV](https://images.trvl-media.com/lodging/91000000/90990000/90989500/90989471/048a25f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/91000000/90990000/90989500/90989471/w6000h3995x0y5-7c6df35f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/91000000/90990000/90989500/90989471/71a41b24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/91000000/90990000/90989500/90989471/w6000h3996x0y0-4c092400.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Barnacle Resort 11.3 km from Looe Key National Marine Sanctuary 8.2/10 Very good (40) "Perfect place for a quiet getaway." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $283 CA $353 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Big-Pine-Key-Hotels-Barnacle-Bed-And-Breakfast.h90989471.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4760000/4759500/4759500/63d12f01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine, pool views ](https://images.trvl-media.com/lodging/5000000/4760000/4759500/4759500/974f08a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, 2 Queen Beds | Terrace/patio](https://images.trvl-media.com/lodging/5000000/4760000/4759500/4759500/13570c88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/5000000/4760000/4759500/4759500/9eff678c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Looe Key Reef Resort 12.6 km from Looe Key National Marine Sanctuary 7.4/10 Good (1001) "We enjoyed our three night stay. We dived Looe Key reef every day through their dive shop. Safe shallow diving with excellent storage, easy access and excellent staff. Left the afternoon/evening open to relax or go into town. About 50 minutes from Key West. Recommend car rental for your stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Timothy CA $223 CA $250 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Ramrod-Key-Hotels-Looe-Key-Reef-Resort.h4759500.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/4000000/3920000/3918200/3918121/95d2903e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lake](https://images.trvl-media.com/lodging/4000000/3920000/3918200/3918121/a0504154.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/4000000/3920000/3918200/3918121/a36bdda4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/4000000/3920000/3918200/3918121/125c52d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sugar Loaf Lodge 19.5 km from Looe Key National Marine Sanctuary 8.2/10 Very good (1002) "Nice family owned spot. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Terry CA $167 CA $188 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Sugarloaf-Key-Hotels-Sugar-Loaf-Lodge.h3918121.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-01&endDate=2025-11-02®ionId=553248621533115813&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLooe-Key-National-Marine-Sanctuary-Hotels.0-l553248621533115813-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLooe-Key-National-Marine-Sanctuary-Hotels.0-l553248621533115813-0.Travel-Guide-Filter-Hotels) ## Top Looe Key National Marine Sanctuary Hotel Reviews ![Parmer's Resort](//images.trvl-media.com/lodging/6000000/5570000/5561500/5561465/6492712a_y.jpg) ### Parmer's Resort 10/10 Excellent "Everything was sweet! Clean, breakfast good, property organized and boys at front desk very nice and polite! Excellent! Will definitely consider going back" [](https://expedia.ca/Little-Torch-Key-Hotels-Parmers-Resort.h5561465.Hotel-Information) ![Star Room Barnacle Resort](//images.trvl-media.com/lodging/112000000/111160000/111152500/111152457/9bf80e17_y.jpg) ### Star Room Barnacle Resort 10/10 Excellent "We loved the location - quiet and secluded - away from everything but not so far away that you felt isolated. All very clean and amenities were as described." [](https://expedia.ca/Big-Pine-Key-Hotels-Star-Room-Barnacle-Bnb.h111152457.Hotel-Information) ![Looe Key Reef Resort](//images.trvl-media.com/lodging/5000000/4760000/4759500/4759500/63d12f01_y.jpg) ### Looe Key Reef Resort 8/10 Good "This is a very REASONABLY priced lodging for the FL Keys so expect simple things. We had a great stay, room was clean, the young gent at the front desk was exceptionally friendly and helpful, ditto at checkout. The beds are comfortable. The shower head had great pressure and the onsite tiki bar is a big plus. There were no plastic cups or coffee maker in the room but there was a microwave and fridge and table with two chairs. The ice machine was not working but there is a quickie mart just next door for that if you needed it. Could the resort be flashier, yes it could but Looe Key Reef Resort offered us a cost effective comfy safe stay in a place where time in the room was not important. We did not use the pool or the dive/snorkle amenities as we came down to fish, but if you wanted that stuff it’s all here. We hope to be back soon." [](https://expedia.ca/Ramrod-Key-Hotels-Looe-Key-Reef-Resort.h4759500.Hotel-Information) ![Florida keys Waterfront,Forever Summer](//images.trvl-media.com/lodging/61000000/60280000/60277700/60277645/0ac065ce_y.jpg) ### Florida keys Waterfront,Forever Summer 10/10 Excellent "We had a great time. Everything was what we were told. Michael was a great host." [](https://expedia.ca/Summerland-Key-Hotels-Forever-Summer.h60277645.Hotel-Information) ![Treehouse Private Village Barnacle Resort](//images.trvl-media.com/lodging/112000000/111160000/111152500/111152459/d1e84791_y.jpg) ### Treehouse Private Village Barnacle Resort 8/10 Good "Great location, quiet with great views!" [](https://expedia.ca/Big-Pine-Key-Hotels-Treehouse-Private-Village.h111152459.Hotel-Information) ![Gorgeous Beachfront Home with a pool. Water views from every direction.](//images.trvl-media.com/lodging/37000000/36320000/36314300/36314286/d96b30e5_y.jpg) ### Gorgeous Beachfront Home with a pool. Water views from every direction. 10/10 Excellent "We have been coming to the keys for years, this has to be top 3 places to stay. Absolutely beautiful. Plenty of room. Deer come up every day. Definitely will stay here again! " [](https://expedia.ca/Big-Pine-Key-Hotels-As-Seen-On-BEACH-HUNTERS-Sn7-Ep5-Feel-Like-You-Are-On-Your-Own-Private-Island.h36314286.Hotel-Information) ![Barnacle Resort](//images.trvl-media.com/lodging/91000000/90990000/90989500/90989471/048a25f3_y.jpg) ### Barnacle Resort 10/10 Excellent "No communication when I couldn’t get into my room. Horrible situation. DO NOT STAY AT THIS PROPERTY!! Total scam. " [](https://expedia.ca/Big-Pine-Key-Hotels-Barnacle-Bed-And-Breakfast.h90989471.Hotel-Information) ![Your Best Fishing And Relaxing Experience! 2/2 Waterfront Home](//images.trvl-media.com/lodging/35000000/34180000/34172400/34172307/12b49e2f_y.jpg) ### Your Best Fishing And Relaxing Experience! 2/2 Waterfront Home 10/10 Excellent "This is a nice house that has everything you need for a vacation on the water in the Keys. The house is perfect for a small family or other group - in fact the guest bedroom can easily sleep 3 people. The outside area is spacious, with an excellent dock area for a boat - in my case I docked my motorized fishing kayak there. The house is located on the corner junction of two canals and only a couple of hundred yards from the open water of Pine Channel, so if you are there to fish, it's an ideal location. Communication with the property owner was excellent. Unfortunately, I had to cut my stay short due to a medical situation back home, but I would definitely stay here again." [](https://expedia.ca/Little-Torch-Key-Hotels-Your-Best-Fishing-And-Relaxing-Experience-Waterfront-Home.h34172307.Hotel-Information) ![Summerland Breeze - Three house retreat, perfect for multiple families](//images.trvl-media.com/lodging/67000000/66310000/66304800/66304795/f1085f26_y.jpg) ### Summerland Breeze - Three house retreat, perfect for multiple families 10/10 Excellent "Beautiful oceanfront property with wonderful pool - great space for large families " [](https://expedia.ca/Summerland-Key-Hotels-Summerland-Breeze-Three-House-Retreat.h66304795.Hotel-Information) ## Hotels near other Looe Key National Marine Sanctuary attractions [](https://www.expedia.ca/Munson-Island-Hotels.0-l874556621345521664-0.Travel-Guide-Filter-Hotels) ### Munson Island Commune with nature and explore the great outdoors at Munson Island during your travels in Big Pine Key. While you're in the area, stroll along the beaches. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=874556621345521664) [](https://www.expedia.ca/Big-Munson-Island-Hotels.0-l874555262665744384-0.Travel-Guide-Filter-Hotels) ### Big Munson Island Commune with nature and explore the great outdoors at Big Munson Island during your travels in Big Pine Key. While you're in the area, stroll along the beaches. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=874555262665744384) [](https://www.expedia.ca/Newfound-Harbor-Keys-Hotels.0-l874556615670603776-0.Travel-Guide-Filter-Hotels) ### Newfound Harbor Keys Commune with nature and explore the great outdoors at Newfound Harbor Keys during your travels in Big Pine Key. While you're in the area, wander around the natural setting. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=874556615670603776) [](https://www.expedia.ca/Hopkins-Island-Hotels.0-l874555017892454400-0.Travel-Guide-Filter-Hotels) ### Hopkins Island Commune with nature and explore the great outdoors at Hopkins Island during your travels in Big Pine Key. While you're in the area, wander around the natural setting. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=874555017892454400) [](https://www.expedia.ca/Cook-Island-Hotels.0-l553248635976197877-0.Travel-Guide-Filter-Hotels) ### Cook Island Commune with nature and explore the great outdoors at Cook Island during your travels in Big Pine Key. While you're in the area, wander around the natural setting. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635976197877) [](https://www.expedia.ca/Pye-Key-Hotels.0-l874555935142699008-0.Travel-Guide-Filter-Hotels) ### Pye Key Commune with nature and explore the great outdoors at Pye Key during your travels in Summerland Key. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=874555935142699008) [](https://www.expedia.ca/Coupon-Bight-Aquatic-Preserve-Hotels.0-l6177699-0.Travel-Guide-Filter-Hotels) ### Coupon Bight Aquatic Preserve Commune with nature and explore the great outdoors at Coupon Bight Aquatic Preserve during your travels in Big Pine Key. While in this romantic area, you can enjoy the restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6177699) ## Frequently asked questions ### What's the area like around Looe Key National Marine Sanctuary? > Looe Key National Marine Sanctuary is located in an area that travelers like for its local tours. When you want to settle in and find a place to stay, check out some of the hotels and other accommodations that Expedia offers in the area. ### What's the best place to stay close to Looe Key National Marine Sanctuary? > [Barnacle Resort](https://www.expedia.ca/Big-Pine-Key-Hotels-Barnacle-Bed-And-Breakfast.h90989471.Hotel-Information) is one of the top choices for your stay based on our traveler data, and this B&B offers free parking and a rooftop terrace. You'll find it 7 mi (11.3 km) from Looe Key National Marine Sanctuary. Another good choice is [Looe Key Reef Resort](https://www.expedia.ca/Ramrod-Key-Hotels-Looe-Key-Reef-Resort.h4759500.Hotel-Information), located 7.8 mi (12.6 km) away. ### If I need to cancel the hotel reservation for my stay near Looe Key National Marine Sanctuary, will I receive a refund? > Yes! The majority of hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view the top deals on offer near Looe Key National Marine Sanctuary. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [Bahia Honda Key Hotels](https://www.expedia.ca/Bahia-Honda-Key-Hotels.d553248635083902001.Travel-Guide-Hotels) - [Bay Point Hotels](https://www.expedia.ca/Bay-Point-Hotels.d553248635976383913.Travel-Guide-Hotels) - [Big Coppitt Key Hotels](https://www.expedia.ca/Big-Coppitt-Key-Hotels.d553248635975850102.Travel-Guide-Hotels) - [Big Pine Key Hotels](https://www.expedia.ca/Big-Pine-Key-Hotels.d7195.Travel-Guide-Hotels) - [Big Torch Key Hotels](https://www.expedia.ca/Big-Torch-Key-Hotels.d553248635974614531.Travel-Guide-Hotels) - [Hotels near Calusa Beach](https://www.expedia.ca/Calusa-Beach-Hotels.0-l553248635983993598-0.Travel-Guide-Filter-Hotels) - [Hotels near Cook Island](https://www.expedia.ca/Cook-Island-Hotels.0-l553248635976197877-0.Travel-Guide-Filter-Hotels) - 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