Title: Book the Best Hartsville SPA Resorts from CA $201 - Spa Hotels in Hartsville, SC | Expedia.ca [Hartsville Travel Guide](https://expedia.ca/Hartsville.dx7762)[Hotels in Hartsville](https://expedia.ca/Hartsville-Hotels.d7762.Travel-Guide-Hotels)[Vacation Rentals in Hartsville](https://expedia.ca/Hartsville-Vacation-Rentals.d7762.Travel-Guide-VacationRentals)[Things to do in Hartsville](https://expedia.ca/Things-To-Do-In-Hartsville.d7762.Travel-Guide-Activities)[Hartsville Car Rentals](https://expedia.ca/Car-Rentals-In-Hartsville.d7762.Car-Rental-Guide)[Hartsville Vacation Packages](https://expedia.ca/Hartsville.d7762.Destination-Travel-Guides) ![The Midnight Rooster is my go to spot in my hometown of Hartsville, SC. Great brunch and coffee! Love the courtyard!](https://images.trvl-media.com/place/7762/94f24b5a-6f19-4be1-9683-553b4be73135.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Caroline Nunez ![](https://images.trvl-media.com/place/7762/94f24b5a-6f19-4be1-9683-553b4be73135.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Hartsville Spa Hotels Tonight [Mar 19 - Mar 20](https://www.expedia.ca/Hotel-Search?regionId=7762&startDate=2026-03-19&endDate=2026-03-20&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 20 - Mar 21](https://www.expedia.ca/Hotel-Search?regionId=7762&startDate=2026-03-20&endDate=2026-03-21&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=7762&startDate=2026-03-20&endDate=2026-03-22&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 27 - Mar 29](https://www.expedia.ca/Hotel-Search?regionId=7762&startDate=2026-03-27&endDate=2026-03-29&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Hartsville hotels with a spa ![Sports facility](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/713c2524.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/af0558b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/05b9e041.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/e5aa7c6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Florence, Tapestry Collection by Hilton [](https://www.expedia.ca/Florence-Hotels-Hotel-Florence.h6128999.Hotel-Information) Florence 8.8/10 Excellent (622 reviews) "Nice room. Good breakfast. Interesting town" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Noel CA $179 CA $201 total includes taxes & fees Apr 5 - Apr 6 [](https://www.expedia.ca/Florence-Hotels-Hotel-Florence.h6128999.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-02&endDate=2026-04-03®ionId=7762&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Choose what matters most at spa hotels in Hartsville Pool Breakfast included Hot tub 4 stars 5 stars ## Top Hartsville Hotel Reviews ## Frequently asked questions ### How much does a spa hotel in Hartsville cost? ### Is it cheaper to book a spa hotel in Hartsville with flights as part of a package deal? ### Are there any unique spa experiences available in Hartsville? > Renew – The Med Spa provides a unique combination of medical aesthetics and wellness in a serene, upscale environment, offering non-invasive cosmetic procedures alongside luxurious wellness treatments, personalised by medical professionals and licensed therapists. > > > The Experience Salon and Head Spa offers a distinctive fusion of high-end hairstyling and exclusive head spa treatments, including scalp massages and custom hair masks, designed as a true escape for relaxation and indulgence. > > > Peace & Harmony Day Spa features a variety of relaxing services such as Swedish massage, lymphatic drainage, cupping therapy, and hot stone therapy, offering a holistic approach to body wellness. > > > Luxe Beauty Bar and Spa offers advanced skin treatments like microneedling, microdermabrasion facials, chemical peels, and a Luxe Head Spa, combining cutting-edge technology with personalised care for skin rejuvenation. > > > The Sanctuary Spa focuses on whole-body wellness with facials, sugaring, spray tans, and microchanneling in a calming environment designed to promote healing and relaxation. ### How can I save on a spa hotel in Hartsville with Expedia? ### Can I cancel my spa hotel reservation on Expedia? ## Explore a world of travel with Expedia - 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