Title: Hotels by Best Western in Depew from CA $127 | Expedia.ca [Depew Travel Guide](https://expedia.ca/Depew.dx6338362)[Hotels in Depew](https://expedia.ca/Depew-Hotels.d6338362.Travel-Guide-Hotels)[Vacation Rentals in Depew](https://expedia.ca/Depew-Vacation-Rentals.d6338362.Travel-Guide-VacationRentals)[Flights to Depew](https://expedia.ca/Cheap-Flights-To-Depew.d6338362.Travel-Guide-Flights)[Things to do in Depew](https://expedia.ca/Things-To-Do-In-Depew.d6338362.Travel-Guide-Activities)[Depew Car Rentals](https://expedia.ca/Car-Rentals-In-Depew.d6338362.Car-Rental-Guide)[Depew Vacation Packages](https://expedia.ca/Depew.d6338362.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Best Western in Depew from CA $127 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 29 - Oct 30](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2025-10-29&endDate=2025-10-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 30 - Oct 31](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2025-10-30&endDate=2025-10-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Depew Best Western Hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/c135a4a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/23031bfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/e11dd135.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/098077ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Summit Inn Niagara Falls 8.6/10 Excellent (1384) "Nice place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yanil CA $112 CA $127 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Niagara-Falls-Hotels-Best-Western-Summit-Inn.h5183.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/100000000/99810000/99802700/99802648/7d3bff92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/100000000/99810000/99802700/99802648/97ad4987.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/100000000/99810000/99802700/99802648/b3c0a8a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/100000000/99810000/99802700/99802648/dec807b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Buffalo Inn & Suites Buffalo 8.6/10 Excellent (829) "Breakfast was amazing and the property was great. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicholas CA $140 CA $159 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Eva-Hotel.h99802648.Hotel-Information) ![Suite, 1 King Bed, Non Smoking, Jetted Tub](https://images.trvl-media.com/lodging/7000000/6790000/6785900/6785857/ed7545be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/7000000/6790000/6785900/6785857/ff355930.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6790000/6785900/6785857/ce122a7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/7000000/6790000/6785900/6785857/2d06ae33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western on the Avenue Downtown Buffalo 8.6/10 Excellent (1010) "Very nice place with great breakfast, clean rooms, quiet AC unit and friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alexander CA $200 CA $233 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Buffalo-Hotels-Best-Western-On-The-Avenue.h6785857.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-12&endDate=2025-11-13®ionId=6338362&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDepew-Hotels-Best-Western.0-0-d6338362--bBestWestern.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDepew-Hotels-Best-Western.0-0-d6338362--bBestWestern.Travel-Guide-Filter-Hotels) ## Top Depew Hotel Reviews ![CenterWay Hotel Tonawanda](//images.trvl-media.com/lodging/1000000/80000/76400/76371/66013c67_y.jpg) ### CenterWay Hotel Tonawanda 10/10 Excellent "cheap clean and worth it for the price. " [](https://expedia.ca/Buffalo-Hotels-CenterWay-Hotel-Tonawanda.h76371.Hotel-Information) ![Garden Place Hotel](//images.trvl-media.com/lodging/2000000/1070000/1060800/1060721/40afc3e4_y.jpg) ### Garden Place Hotel 10/10 Excellent "We stayed for only a night while in town for our anniversary, and thoroughly enjoyed our room. The bed was incredibly comfortable, the hot tub was clean, and the room was very spacious. The staff was very kind and helpful, and parking waz ample. We didn't eat breakfast there so cannot comment on that. " [](https://expedia.ca/Buffalo-Hotels-Garden-Place-Hotel.h1060721.Hotel-Information) ![Wyndham Garden Buffalo Downtown](//images.trvl-media.com/lodging/1000000/160000/159000/158959/2e0799e1_y.jpg) ### Wyndham Garden Buffalo Downtown 10/10 Excellent "The lady at the front desk was the absolute best! Very helpful and kind and supportive " [](https://expedia.ca/Buffalo-Hotels-Wyndham-Garden-Buffalo-Downtown.h158959.Hotel-Information) ![Buffalo Airport Hotel](//images.trvl-media.com/lodging/1000000/30000/26100/26001/90223c0d_y.jpg) ### Buffalo Airport Hotel 10/10 Excellent "Good having an airport shuttle " [](https://expedia.ca/Buffalo-Hotels-Buffalo-Airport-Hotel.h26001.Hotel-Information) ![M Hotel Buffalo](//images.trvl-media.com/lodging/1000000/20000/11300/11231/2c4d5593_y.jpg) ### M Hotel Buffalo 10/10 Excellent "Amazing" [](https://expedia.ca/Buffalo-Hotels-Millennium-Buffalo.h11231.Hotel-Information) ![Sleep Inn & Suites Buffalo Airport](//images.trvl-media.com/lodging/1000000/90000/85100/85007/ae021a7d_y.jpg) ### Sleep Inn & Suites Buffalo Airport 10/10 Excellent "Everything was clean and convenient but staff was a little rude (especially the shuttle guy) and the common areas near the lobby looked pretty beat up. Everything in the room itself was perfectly clean and functional though, including one of the most comfortable beds I've ever seen in a hotel. The free breakfast was great too. Overall I'd definitely recommend this place." [](https://expedia.ca/Buffalo-Hotels-Sleep-Inn-Suites-Buffalo-Airport.h85007.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Buffalo Amherst](//images.trvl-media.com/lodging/25000000/24730000/24723600/24723591/456d3072_y.jpg) ### La Quinta Inn & Suites by Wyndham Buffalo Amherst 10/10 Excellent "Amazingly surprised" [](https://expedia.ca/Buffalo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Buffalo-Amherst.h24723591.Hotel-Information) ![Hampton Inn Buffalo - Amherst, NY](//images.trvl-media.com/lodging/51000000/50710000/50706500/50706489/63fc013f_y.jpg) ### Hampton Inn Buffalo - Amherst, NY 10/10 Excellent "Big, clean, comfortable room and bed. Had all of the amenities we needed and went a step above other Hamptons with an additional bottle of soap at the sink. We were so happy to see hooks on the wall and extra hooks in the bathroom. We asked Dan, the registration clerk, for a restaurant recommendation. Lebro’s Italian restaurant was his response and it was delicious, reasonably priced, with excellent service. Dan also gave us some good sightseeing tips and thanks to him, we had a great visit to Buffalo!" [](https://expedia.ca/Buffalo-Hotels-Hampton-Inn-Buffalo-Amherst.h50706489.Hotel-Information) ![Hyatt Regency Buffalo / Hotel and Conference Center](//images.trvl-media.com/lodging/1000000/30000/23200/23101/00561234_y.jpg) ### Hyatt Regency Buffalo / Hotel and Conference Center 10/10 Excellent "Went there for the hockey game. Trolley is just outside the door and free to go to the game. Good location. All you need" [](https://expedia.ca/Buffalo-Hotels-Hyatt-Regency-Buffalo-Hotel-And-Conference-Center.h23101.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [5 Star Hotels in Cheektowaga](https://www.expedia.ca/5Star-Cheektowaga-Hotels.s50-0-d7197.Travel-Guide-Filter-Hotels) - [Adam's Mark Hotels in Amherst](https://www.expedia.ca/Amherst-Hotels-Adams-Mark.0-0-d9323--bAdamsMark.Travel-Guide-Filter-Hotels) - [Best Western Hotels in Amherst](https://www.expedia.ca/Amherst-Hotels-Best-Western.0-0-d9323--bBestWestern.Travel-Guide-Filter-Hotels) - [La Quinta Inn & Suites Hotels in Amherst](https://www.expedia.ca/Amherst-Hotels-La-Quinta-Inn-Suites.0-0-d9323--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) - [Marriott Hotels & Resorts in Amherst](https://www.expedia.ca/Amherst-Hotels-Marriott-Hotels-Resorts.0-0-d9323--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) - [Millennium Hotels in Amherst](https://www.expedia.ca/Amherst-Hotels-Millennium-Hotels.0-0-d9323--bMillenniumHotels.Travel-Guide-Filter-Hotels) - 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