Title: Top 10 4 Star Hotels in Sanibel : Find a Four Star Hotel in Sanibel | Expedia.ca [Sanibel Travel Guide](https://expedia.ca/Sanibel.dx9791)[Hotels in Sanibel](https://expedia.ca/Sanibel-Hotels.d9791.Travel-Guide-Hotels)[Vacation Rentals in Sanibel](https://expedia.ca/Sanibel-Vacation-Rentals.d9791.Travel-Guide-VacationRentals)[Flights to Sanibel](https://expedia.ca/Cheap-Flights-To-Sanibel.d9791.Travel-Guide-Flights)[Things to do in Sanibel](https://expedia.ca/Things-To-Do-In-Sanibel.d9791.Travel-Guide-Activities)[Sanibel Car Rentals](https://expedia.ca/Car-Rentals-In-Sanibel.d9791.Car-Rental-Guide)[Sanibel Vacation Packages](https://expedia.ca/Sanibel.d9791.Destination-Travel-Guides) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496714-sanibel.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 4 Star Hotels in Sanibel ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Sanibel 4 Star Hotels Tonight [Oct 18 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=9791&startDate=2025-10-18&endDate=2025-10-19&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 19 - Oct 20](https://www.expedia.ca/Hotel-Search?regionId=9791&startDate=2025-10-19&endDate=2025-10-20&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=9791&startDate=2025-10-24&endDate=2025-10-26&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=9791&startDate=2025-10-31&endDate=2025-11-02&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Sanibel 4 Star Hotels ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Sanibel-Hotels.s40-0-d9791.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Sanibel-Hotels.s40-0-d9791.Travel-Guide-Filter-Hotels) ## Learn more about Sanibel Escape to relaxing Sanibel! Enjoy its island views, beaches, and sunsets. [See all hotels in Sanibel](https://www.expedia.ca/Hotel-Search?startDate=2025-11-02&endDate=2025-11-03&adults=2®ionId=9791) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496714-sanibel.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top Sanibel Hotel Reviews ## Find out more about Sanibel If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Sanibel are calling your name. Known for providing first-rate service in amazing locations, each of the Sanibel 4 Stars hotels lets discerning travelers bask in an unforgettable experience. Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day. It’s all waiting for you at the top four star hotels in Sanibel. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Sanibel, Florida, neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Sanibel hotels with 4 Stars provide everything you need to unwind in style. ## Frequently asked questions ### What are the best 4-star hotels in Sanibel? > Kick back and unwind in 4-star hotel comfort at [Marriott Sanibel Harbour Resort & Spa](https://www.expedia.ca/Fort-Myers-Hotels-Marriott-Sanibel-Harbour-Resort-Spa.h3079.Hotel-Information). Ranked highly by many Expedia guests, it offers designer toiletries and a tennis court. Also consider [Pink Shell Beach Resort and Marina](https://www.expedia.ca/Fort-Myers-Hotels-Pink-Shell-Beach-Resort-And-Marina.h15603.Hotel-Information). A resort and a beach view help make this getaway another traveller favourite in Sanibel. ### How much does it cost to stay in a 4-star hotel in Sanibel? > We can help you quickly find the ideal 4-star hotel for your getaway in Sanibel. Use our filter tool to fine-tune your search by things like price, amenities and property star rating and get access to terrific deals in a few clicks. > > > > - Search for the lowest price ### What's the difference between 5-star and 4-star hotels in Sanibel? > If you decide to spend your vacation at a 4-star hotel in Sanibel, you'll typically find loads of amenities to make sure you're relaxed, such as a pool, gym and restaurant. You can look forward to high-quality service and deluxe accommodations. Go for a 5-star hotel and you'll get a few more bells and whistles — think on-site spas, 24-hour front desk and indulgent turndown services. 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