Santa Isabel Vacation Rentals

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Our top choices for Santa Isabel vacation rentals

Fabulous 2-bedroom house with AC in charming Terranova

Fabulous 2-bedroom house with AC in charming Terranova
Terranova
10.0 out of 10, Exceptional, (1 review)
"The house was spotless, in a quiet neighborhood, easy excess to main road, and entertainment, great location everything close by."
United States
Francisco
The price is CA $111
CA $147 total
includes taxes & fees
Apr 23 - Apr 24
Fabulous 2-bedroom house with AC in charming Terranova

Beautiful 2-bedroom apartment with AC in delightful Tanamá

Beautiful 2-bedroom apartment with AC in delightful Tanamá
Tanamá
The price is CA $124
CA $289 total
includes taxes & fees
Apr 29 - Apr 30
Beautiful 2-bedroom apartment with AC in delightful Tanamá

Ventana al Atlantico at Arecibo 681 Ocean Drive

Ventana al Atlantico at Arecibo 681 Ocean Drive
2.5 star property
Arecibo
7.0 out of 10, Good, (265 reviews)
"The room was clean and the host was a great help. The view was beautiful. "
United States
Gustavo
The price is CA $150
CA $211 total
includes taxes & fees
May 11 - May 12
Ventana al Atlantico at Arecibo 681 Ocean Drive

The Cozy Càsata: A Unique American-Style Cabin in the Mountains of Puerto Rico

The Cozy Càsata: A Unique American-Style Cabin in the Mountains of Puerto Rico
Adjuntas
9.6 out of 10, Exceptional, (15 reviews)
"A beautiful home and a great host! Strongly recommend! "
United States
Brandon C.
The price is CA $218
CA $389 total
includes taxes & fees
Apr 28 - Apr 29
The Cozy Càsata: A Unique American-Style Cabin in the Mountains of Puerto Rico

Arecibo Hotel 2101

Arecibo Hotel 2101
3.0 star property
Arecibo
8.0 out of 10, Very good, (13 reviews)
"The room was clean. It’s very spacious and had everything we need. It was definitely a new experience will definitely highly recommend even though the city is a ghost town had my own parking and had no issues. A few restaurants and bars, and not too far from one of the best beaches in Puerto Rico. "
United States
Michael
The price is CA $170
CA $233 total
includes taxes & fees
Apr 18 - Apr 19
Arecibo Hotel 2101

Hacienda Vista Del Rio 1

Hacienda Vista Del Rio 1
Orocovis
The price is CA $69
CA $189 total
includes taxes & fees
Apr 17 - Apr 18
Hacienda Vista Del Rio 1

Colombian Boricua Apartment 5 minutes from the beach luxury

Colombian Boricua Apartment 5 minutes from the beach luxury
Quebradillas
10.0 out of 10, Exceptional, (1 review)
"Beautiful "
United States
Vanessa C.
The price is CA $78
CA $111 total
includes taxes & fees
Apr 28 - Apr 29
Colombian Boricua Apartment 5 minutes from the beach luxury

VSS La Puntilla Stylish Coastal Getaway Near Beach

VSS La Puntilla Stylish Coastal Getaway Near Beach
Arecibo
The price is CA $117
CA $249 total
includes taxes & fees
Apr 29 - Apr 30
VSS La Puntilla Stylish Coastal Getaway Near Beach

Isabela, Tiny House 2.

Isabela, Tiny House 2.
Isabela
10.0 out of 10, Exceptional, (11 reviews)
"Nice place, quite location beautiful "
United States
Carmen
The price is CA $148
CA $186 total
includes taxes & fees
Apr 21 - Apr 22
Isabela, Tiny House 2.

Cozy 2BR house w/ AC & WiFi in Utuado near Tanama River

Cozy 2BR house w/ AC & WiFi in Utuado near Tanama River
Utuado
10.0 out of 10, Exceptional, (1 review)
The price is CA $158
CA $289 total
includes taxes & fees
Apr 19 - Apr 20
Cozy 2BR house w/ AC & WiFi in Utuado near Tanama River

La Cueva Apt 1 | Boho Oceanfront Escape @ Arecibo

La Cueva Apt 1 | Boho Oceanfront Escape @ Arecibo
Arecibo
The price is CA $173
CA $405 total
includes taxes & fees
Apr 20 - Apr 21
La Cueva Apt 1 | Boho Oceanfront Escape @ Arecibo

Nature's Lodge Escape

Nature's Lodge Escape
Sabana Grande
8.0 out of 10, Very good, (3 reviews)
"Beautiful "
United States
Vanessa C.
The price is CA $41
CA $115 total
includes taxes & fees
Apr 22 - Apr 23
Nature's Lodge Escape

Villa Colon near beach and Top Attractions, Wi-Fi

Villa Colon near beach and Top Attractions, Wi-Fi
Arecibo
10.0 out of 10, Exceptional, (1 review)
"My family and I stayed here while visiting family in the area. It is a great location, close to the beach, pharmacy, bakery, and convenience store all within walking distance."
United States
Hyomara H.
The price is CA $158
CA $267 total
includes taxes & fees
May 5 - May 6
Villa Colon near beach and Top Attractions, Wi-Fi

Cozy 2-bedroom apartment in charming Arecibo with WiFi, AC

Cozy 2-bedroom apartment in charming Arecibo with WiFi, AC
Arecibo
10.0 out of 10, Exceptional, (2 reviews)
"Nice place to stay, sleep and go out!! "
United States
Rosa
The price is CA $165
CA $257 total
includes taxes & fees
Apr 29 - Apr 30
Cozy 2-bedroom apartment in charming Arecibo with WiFi, AC

Marie Guest House w A/C

Marie Guest House w A/C
Camuy
10.0 out of 10, Exceptional, (1 review)
"好"
China
善安
The price is CA $247
CA $348 total
includes taxes & fees
Apr 28 - Apr 29
Marie Guest House w A/C

DK Backyard - Yellow Room

DK Backyard - Yellow Room
Arecibo
10.0 out of 10, Exceptional, (1 review)
"Exelente estancia🙏"
Mexico
Liliana
The price is CA $147
CA $216 total
includes taxes & fees
May 11 - May 12
DK Backyard - Yellow Room

Moderno apartamento cerca de la playa + wifi

Moderno apartamento cerca de la playa + wifi
Arecibo
7.8 out of 10, Good, (9 reviews)
"Clean, water works, ac are functional, easy check in process and great amenities "
United States
Victor G.
The price is CA $172
CA $264 total
includes taxes & fees
Apr 29 - Apr 30
Moderno apartamento cerca de la playa + wifi

DK Backyard's Green Apartment

DK Backyard's Green Apartment
Arecibo
The price is CA $140
CA $209 total
includes taxes & fees
Apr 29 - Apr 30
DK Backyard's Green Apartment

The Eden Oasis - A Private Getaway

The Eden Oasis - A Private Getaway
Bajadero
10.0 out of 10, Exceptional, (1 review)
"The home was beautiful and it was close to the beaches and restaurants. We had a wonderful stay and there were several pleasant surprises. The host was very responsive and welcoming!"
United States
Gladys G.
The price is CA $130
CA $322 total
includes taxes & fees
Apr 29 - Apr 30
The Eden Oasis - A Private Getaway

Arecibo Hotel 2104

Arecibo Hotel 2104
3.0 star property
Arecibo
7.0 out of 10, Good, (12 reviews)
"Convenient, clean, excellent communication throughout. Very happy with our stay!"
United States
Henry
The price is CA $129
CA $193 total
includes taxes & fees
Apr 18 - Apr 19
Arecibo Hotel 2104
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Isabel Hotel Reviews

Find out more about Santa Isabel

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Santa Isabel. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Are there vacation rentals in Santa Isabel?

Yes, we have vacation rentals near top attractions in Santa Isabel, or you can choose a secluded option if you'd like a relaxing place to stay.

What's the top vacation rental that Santa Isabel has to offer?

3-Bedroom House in Quebradillas: You might want to consider this vacation rental near Santa Isabel, which is located near the airport and has a terrace, a garden, and WiFi to put you at ease in your new surroundings. This vacation rental also comes with free parking to give you added peace of mind.

What can I see and do in Santa Isabel?

Explore the area and family-friendly sights such as Maricao Fish Hatchery, or get out into nature at a spot like Tanamá River. Camuy River Cave Park and Cueva Ventana are a couple of places you'll find in the larger area.

What are vacation rentals like in Santa Isabel?

Vacation rentals are privately owned accommodations you can book for a short or long stay in Santa Isabel. Vacation rentals feature extras such as patios, hot tubs, and fire pits so you'll feel right at home. If you're concerned about cleanliness, a vacation rental can provide a sense of safety away from shared hotel elevators and busy concierge desks while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a traditional hotel, which makes a vacation rental a popular option for small groups.