Medical Center District

San Antonio

River walk in San Antonio
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Popular places to visit

Things to do


Medical Center District Hotel Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
The price is CA $122 per night from Mar 23 to Mar 24
CA $122
CA $144 total
Mar 23 - Mar 24
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (3,210 reviews)
Not what it looks like on line. The check in staff is very nice however if you have questions or concerns about anything they are ver dismissive. The spa temperature was so high the one night that an elderly man got burns on his feet from the water. When we reported it to the night staff they said ...

Reviewed on Mar 17, 2026

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
The price is CA $138 per night from Apr 3 to Apr 4
CA $138
CA $165 total
Apr 3 - Apr 4
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy a free area shuttle, room service, and a 24-hour fitness center. Our guests praise the helpful ...
8.6/10 Excellent! (1,011 reviews)
Clean room

Reviewed on Mar 17, 2026

San Antonio Marriott Northwest Medical Center
Park Inn by Radisson

Park Inn by Radisson

2 out of 5
7500 Louis Pasteur Drive San Antonio TX
The price is CA $87 per night from Apr 13 to Apr 14
CA $87
CA $102 total
Apr 13 - Apr 14
includes taxes & fees
Stay at this motel in San Antonio. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.2/10 Good! (1,000 reviews)
Nothing out of the ordinary but in a good way.

Reviewed on Feb 28, 2026

Park Inn by Radisson
Riverwalk Plaza

Riverwalk Plaza

4 out of 5
100 Villita Street San Antonio TX
The price is CA $134 per night from Apr 5 to Apr 6
CA $134
CA $159 total
Apr 5 - Apr 6
includes taxes & fees
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the restaurant and the ...
8/10 Very Good! (6,386 reviews)
Very clean room. Amazing location

Reviewed on Mar 18, 2026

Riverwalk Plaza
Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

4.5 out of 5
150 E Houston St San Antonio TX
The price is CA $207 per night from Mar 22 to Mar 23
CA $207
CA $284 total
Mar 22 - Mar 23
includes taxes & fees
Book a stay at this luxury hotel in San Antonio. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.4/10 Exceptional! (2,554 reviews)
1st time visitors to San Antonio. The hotel is perfectly located to the River Walk & The Alamo, and very walkable. Our biggest complaint is with the room temperature. It was very warm & made sleeping and getting ready in a ventless bathroom quite uncomfortable.

Reviewed on Mar 18, 2026

Hotel Valencia Riverwalk
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

3.5 out of 5
9700 West Military Drive San Antonio TX
The price is CA $150 per night from Apr 13 to Apr 14
CA $150
CA $234 total
Apr 13 - Apr 14
includes taxes & fees
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the helpful staff in ...
9/10 Wonderful! (1,517 reviews)
This is my third time staying here and I have definitely noticed a few things have changed and not for the better. Just seemed to me the customer has to suffer with minimal housekeeping and not the customer service there was before.

Reviewed on Mar 18, 2026

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

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Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Dub Farris Athletic Complex.

Northwest Side
Sam's Burger Joint

Midtown

4.5/5(2 area reviews)

Unique features of Midtown include the river views and bars. Make a stop by San Antonio Zoo and Aquarium or The DoSeum while you're exploring the area.

Midtown
Historic architecture Spanish San Antonio Texas Mission San Jose on a cloudy day

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
One of the coolest bars in San Antonio. Definitely check it out.

Tobin Hill

Though Tobin Hill might not have many top sights, you can venture to the surrounding area to see attractions like San Antonio Zoo and Aquarium and San Antonio Museum of Art.

Tobin Hill
Marion Koogler McNay Art Museum which includes art and interior views as well as an individual male

Uptown

While visiting Uptown, you might make a stop by sights like San Antonio Zoo and Aquarium and Marion Koogler McNay Art Museum.

Uptown
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Alamo Heights

You'll enjoy the museums and coffeehouses in Alamo Heights. You might want to make time for a stop at San Antonio River or Toilet Seat Museum.

Alamo Heights


Medical Center District

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