Medical Center District

San Antonio

River walk in San Antonio
River walk in San Antonio
SanAntonio_SouthTexasMedicalCenter_6193120_01

Popular places to visit

Things to do


Medical Center District Hotel Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
The price is CA $104 per night from Mar 23 to Mar 24
CA $104
CA $123 total
Mar 23 - Mar 24
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (3,236 reviews)
nice place everything

Reviewed on Mar 22, 2026

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $139 per night from Apr 3 to Apr 4
CA $139
CA $165 total
Apr 3 - Apr 4
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy a free area shuttle, room service, and a 24-hour fitness center. Our guests praise the helpful ...
8.6/10 Excellent! (1,010 reviews)
Great stay overall. Very clean and nice rooms. Bar area was great. Only complaint is that our room didn’t get any colder than 66 degrees and found myself waking up hot at night.

Reviewed on Mar 22, 2026

San Antonio Marriott Northwest Medical Center
Park Inn by Radisson

Park Inn by Radisson

2 out of 5
7500 Louis Pasteur Drive San Antonio TX
The price is CA $88 per night from Apr 6 to Apr 7
CA $88
CA $103 total
Apr 6 - Apr 7
includes taxes & fees
Stay at this motel in San Antonio. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.2/10 Good! (1,003 reviews)
Room smelt like smoke and felt dirty. Parking was terrible.

Reviewed on Mar 21, 2026

Park Inn by Radisson
Riverwalk Plaza

Riverwalk Plaza

4 out of 5
100 Villita Street San Antonio TX
The price is CA $159 per night from Apr 1 to Apr 2
CA $159
CA $188 total
Apr 1 - Apr 2
includes taxes & fees
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the restaurant and the ...
8/10 Very Good! (6,403 reviews)
I had to call the front desk to get the room cleaned after 2 days I not having room service.

Reviewed on Mar 21, 2026

Riverwalk Plaza
Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

4.5 out of 5
150 E Houston St San Antonio TX
The price is CA $166 per night from Apr 1 to Apr 2
CA $166
CA $235 total
Apr 1 - Apr 2
includes taxes & fees
Book a stay at this luxury hotel in San Antonio. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.4/10 Exceptional! (2,562 reviews)
Fun times

Reviewed on Mar 21, 2026

Hotel Valencia Riverwalk
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

3.5 out of 5
9700 West Military Drive San Antonio TX
The price is CA $144 per night from Apr 13 to Apr 14
CA $144
CA $227 total
Apr 13 - Apr 14
includes taxes & fees
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the helpful staff in ...
9/10 Wonderful! (1,521 reviews)
Great hotel with very clean, comfortable rooms and excellent attention to detail. The staff was incredibly friendly, professional, and always willing to help with a smile. They made our stay feel welcoming and stress-free. Highly recommended — we will definitely be coming back!

Reviewed on Mar 21, 2026

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

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Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Dub Farris Athletic Complex.

Northwest Side
Sam's Burger Joint

Midtown

4.5/5(2 area reviews)

Unique features of Midtown include the river views and bars. Make a stop by San Antonio Zoo and Aquarium or The DoSeum while you're exploring the area.

Midtown
Historic architecture Spanish San Antonio Texas Mission San Jose on a cloudy day

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
One of the coolest bars in San Antonio. Definitely check it out.

Tobin Hill

Though Tobin Hill might not have many top sights, you can venture to the surrounding area to see attractions like San Antonio Zoo and Aquarium and San Antonio Museum of Art.

Tobin Hill
Marion Koogler McNay Art Museum which includes art and interior views as well as an individual male

Uptown

While visiting Uptown, you might make a stop by sights like San Antonio Zoo and Aquarium and Marion Koogler McNay Art Museum.

Uptown
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Alamo Heights

You'll enjoy the museums and coffeehouses in Alamo Heights. You might want to make time for a stop at San Antonio River or Toilet Seat Museum.

Alamo Heights


Medical Center District

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