Title: 10 Best Hotels in Medical Center District, San Antonio for 2025 | Expedia.ca

  

[Medical Center District Travel Guide](https://expedia.ca/San-Antonio-Medical-Center-District.dx553248635978913844)[Vacation Rentals in San Antonio](https://expedia.ca/San-Antonio-Vacation-Rentals.d178303.Travel-Guide-VacationRentals)[Flights to San Antonio](https://expedia.ca/Cheap-Flights-To-San-Antonio.d178303.Travel-Guide-Flights)[Things to do in San Antonio](https://expedia.ca/Things-To-Do-In-San-Antonio.d178303.Travel-Guide-Activities)[Medical Center District Car Rentals](https://expedia.ca/Car-Rentals-In-Medical-Center-District.d553248635978913844.Car-Rental-Guide)[Medical Center District Vacations](https://expedia.ca/Medical-Center-District.d553248635978913844.Destination-Travel-Guides)

![River walk in San Antonio](https://images.trvl-media.com/place/553248635978913844/ef5a7faf-f6d9-4f7e-b325-ac477c5ad14d.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Hotels in Medical Center District, San Antonio

![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg)

### 

Change your mind

Book hotels with free cancellation

![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg)

### 

Treat yourself

Sign in to save 10% or more on thousands of hotels

[Sign in](https://www.expedia.ca/login)

![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg)

### 

Be picky

Search almost a million properties worldwide

## Go beyond your typical stay in Medical Center District

Apart hotel

[](https://www.expedia.ca/Hotel-Search?destination=Medical+Center+District%2C+San+Antonio%2C+Texas%2C+United+States+of+America&regionId=553248635978913844&latLong=29.506237%2C-98.57686&adults=2&startDate=2025-10-15&d1=2025-10-15&endDate=2025-10-17&d2=2025-10-17&lodging=APART_HOTEL)

Spa

[](https://www.expedia.ca/Hotel-Search?destination=Medical+Center+District%2C+San+Antonio%2C+Texas%2C+United+States+of+America&regionId=553248635978913844&latLong=29.506237%2C-98.57686&adults=2&startDate=2025-10-15&d1=2025-10-15&endDate=2025-10-17&d2=2025-10-17&amenities=SPA_ON_SITE)

Family friendly

[](https://www.expedia.ca/Hotel-Search?destination=Medical+Center+District%2C+San+Antonio%2C+Texas%2C+United+States+of+America&regionId=553248635978913844&latLong=29.506237%2C-98.57686&adults=2&startDate=2025-10-15&d1=2025-10-15&endDate=2025-10-17&d2=2025-10-17&travelerType=family_friendly)

Pool

[](https://www.expedia.ca/Hotel-Search?destination=Medical+Center+District%2C+San+Antonio%2C+Texas%2C+United+States+of+America&regionId=553248635978913844&latLong=29.506237%2C-98.57686&adults=2&startDate=2025-10-15&d1=2025-10-15&endDate=2025-10-17&d2=2025-10-17&amenities=POOL)

Hot tub

[](https://www.expedia.ca/Hotel-Search?destination=Medical+Center+District%2C+San+Antonio%2C+Texas%2C+United+States+of+America&regionId=553248635978913844&latLong=29.506237%2C-98.57686&adults=2&startDate=2025-10-15&d1=2025-10-15&endDate=2025-10-17&d2=2025-10-17&amenities=HOT_TUB)

Pet friendly

[](https://www.expedia.ca/Hotel-Search?destination=Medical+Center+District%2C+San+Antonio%2C+Texas%2C+United+States+of+America&regionId=553248635978913844&latLong=29.506237%2C-98.57686&adults=2&startDate=2025-10-15&d1=2025-10-15&endDate=2025-10-17&d2=2025-10-17&amenities=PETS)

Apart­ment

[](https://www.expedia.ca/Hotel-Search?destination=Medical+Center+District%2C+San+Antonio%2C+Texas%2C+United+States+of+America&regionId=553248635978913844&latLong=29.506237%2C-98.57686&adults=2&startDate=2025-10-15&d1=2025-10-15&endDate=2025-10-17&d2=2025-10-17&lodging=APARTMENT)

Cottage

[](https://www.expedia.ca/Hotel-Search?destination=Medical+Center+District%2C+San+Antonio%2C+Texas%2C+United+States+of+America&regionId=553248635978913844&latLong=29.506237%2C-98.57686&adults=2&startDate=2025-10-15&d1=2025-10-15&endDate=2025-10-17&d2=2025-10-17&lodging=COTTAGE)

Waterpark

[](https://www.expedia.ca/Hotel-Search?destination=Medical+Center+District%2C+San+Antonio%2C+Texas%2C+United+States+of+America&regionId=553248635978913844&latLong=29.506237%2C-98.57686&adults=2&startDate=2025-10-15&d1=2025-10-15&endDate=2025-10-17&d2=2025-10-17&amenities=WATER_PARK)

Condo

[](https://www.expedia.ca/Hotel-Search?destination=Medical+Center+District%2C+San+Antonio%2C+Texas%2C+United+States+of+America&regionId=553248635978913844&latLong=29.506237%2C-98.57686&adults=2&startDate=2025-10-15&d1=2025-10-15&endDate=2025-10-17&d2=2025-10-17&lodging=CONDO)

Villa

[](https://www.expedia.ca/Hotel-Search?destination=Medical+Center+District%2C+San+Antonio%2C+Texas%2C+United+States+of+America&regionId=553248635978913844&latLong=29.506237%2C-98.57686&adults=2&startDate=2025-10-15&d1=2025-10-15&endDate=2025-10-17&d2=2025-10-17&lodging=VILLA)

Farm

[](https://www.expedia.ca/Hotel-Search?destination=Medical+Center+District%2C+San+Antonio%2C+Texas%2C+United+States+of+America&regionId=553248635978913844&latLong=29.506237%2C-98.57686&adults=2&startDate=2025-10-15&d1=2025-10-15&endDate=2025-10-17&d2=2025-10-17&lodging=AGRITOURISM)

## Check prices for these dates

Tonight

[Oct 1 - Oct 2](https://www.expedia.ca/Hotel-Search?regionId=553248635978913844&startDate=2025-10-01&endDate=2025-10-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Oct 2 - Oct 3](https://www.expedia.ca/Hotel-Search?regionId=553248635978913844&startDate=2025-10-02&endDate=2025-10-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=553248635978913844&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248635978913844&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Medical Center District hotels and places to stay

![Front of property](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/w9000h6173x0y15-23603cae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/ded9f09f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/8fcc83d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/9337ea37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

Medical Center District

8.6/10

Excellent

(2971)

"Great hotel and clean"

CA $124

CA $146 total

includes taxes & fees

Oct 3 - Oct 4

[](https://www.expedia.ca/San-Antonio-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Antonio-Medical-Ctr-NW.h1613977.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4200/4192/aa83e7de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 6:00 AM to 11:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/4200/4192/d3568343.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/1000000/10000/4200/4192/053f15e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/10000/4200/4192/0df91985.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### San Antonio Marriott Northwest Medical Center

Medical Center District

8.6/10

Excellent

(1032)

"Clean hotel."

CA $138

CA $164 total

includes taxes & fees

Oct 5 - Oct 6

[](https://www.expedia.ca/San-Antonio-Hotels-San-Antonio-Marriott-Northwest.h4192.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/69000000/68850000/68847400/68847371/3a049706.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/69000000/68850000/68847400/68847371/e7d952d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/69000000/68850000/68847400/68847371/144908d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, premium bedding, desk, laptop workspace](https://images.trvl-media.com/lodging/69000000/68850000/68847400/68847371/92301729.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites by Marriott San Antonio Medical Center

Medical Center District

9.0/10

Wonderful

(1027)

"Staff was excellent "

CA $123

CA $143 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/San-Antonio-Hotels-Fairfield-Inn-Suites-By-Marriott-San-Antonio-Medical-Center.h68847371.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/60000/59300/59226/444a09ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/60000/59300/59226/e4545fb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/60000/59300/59226/c11a39af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/60000/59300/59226/e4f8bf54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites San Antonio Northwest Medical Center

Medical Center District

9.2/10

Wonderful

(1292)

"Friendly staff."

CA $125

CA $148 total

includes taxes & fees

Oct 6 - Oct 7

[](https://www.expedia.ca/San-Antonio-Hotels-Drury-Inn-Suites-San-Antonio-Northwest-Medical-Center.h59226.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12600/12556/2045bf85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/12600/12556/e9bba3f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/12600/12556/1cc9e707.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/20000/12600/12556/42d97754.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Courtyard by Marriott Medical Center San Antonio

Medical Center District

8.8/10

Excellent

(1001)

"Room is clean, staff is very nice."

CA $124

CA $147 total

includes taxes & fees

Oct 9 - Oct 10

[](https://www.expedia.ca/San-Antonio-Hotels-Courtyard-By-Marriott-Medical-Center-San-Antonio.h12556.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/1000000/30000/28200/28102/034bcb0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast area](https://images.trvl-media.com/lodging/1000000/30000/28200/28102/368d725c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/28200/28102/853b5bbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/28200/28102/ea36f701.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Park Inn by Radisson

Medical Center District

7.2/10

Good

(1000)

"Yes, everything was decent and nice."

CA $85

CA $99 total

includes taxes & fees

Oct 19 - Oct 20

[](https://www.expedia.ca/San-Antonio-Hotels-Welcome-Inn-San-Antonio-Medical-Center.h28102.Hotel-Information)

![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/50000/40500/40467/32f5e634.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/50000/40500/40467/910ea91c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/50000/40500/40467/f6e7b585.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/1000000/50000/40500/40467/5cc41c43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### SpringHill Suites by Marriott San Antonio Medical Center/NW

Medical Center District

8.8/10

Excellent

(1000)

"Nice hotel"

CA $141

CA $166 total

includes taxes & fees

Oct 5 - Oct 6

[](https://www.expedia.ca/San-Antonio-Hotels-SpringHill-Suites-By-Marriott-San-Antonio-Medical-CenterNW.h40467.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/97000000/96190000/96182100/96182039/1b117ba4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 Queen Deluxe Suites](https://images.trvl-media.com/lodging/97000000/96190000/96182100/96182039/a72cf5fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/97000000/96190000/96182100/96182039/82bbe653.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96190000/96182100/96182039/a0da5709.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Atria Inn & Suites

Medical Center District

7.6/10

Good

(259)

"Nice and helpful staff "

CA $69

CA $80 total

includes taxes & fees

Oct 5 - Oct 6

[](https://www.expedia.ca/San-Antonio-Hotels-9727-Fredericksburg-Rd.h96182039.Hotel-Information)

![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/60000/50600/50555/8636994f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/60000/50600/50555/8b9aed83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/60000/50600/50555/21be1695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/60000/50600/50555/ef1bc714.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Motel 6 San Antonio, TX - Northwest Medical Center

Medical Center District

6.0/10

(1000)

"Really enjoyed our stay"

CA $61

CA $72 total

includes taxes & fees

Oct 5 - Oct 6

[](https://www.expedia.ca/San-Antonio-Hotels-Motel-6-San-Antonio.h50555.Hotel-Information)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/12000000/11750000/11744300/11744297/63a40a4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/12000000/11750000/11744300/11744297/e79204bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/12000000/11750000/11744300/11744297/39b28cd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/12000000/11750000/11744300/11744297/ca8040db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Medical Center District

6.6/10

(1001)

"Hotel was in close vicinity of hospitals. Rooms.were good size and clean. Breakfast in the am. I Would definitely stay here again! "

CA $85

CA $99 total

includes taxes & fees

Oct 8 - Oct 9

[](https://www.expedia.ca/San-Antonio-Hotels-Country-Inn-Suites-By-Radisson.h11744297.Hotel-Information)

![Desk, laptop workspace, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/84000000/83410000/83406000/83405963/8267ae6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/84000000/83410000/83406000/83405963/b35dac08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/84000000/83410000/83406000/83405963/11140055.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/84000000/83410000/83406000/83405963/9eaddd06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Studio 6 San Antonio, Tx - Northwest Medical Center

Medical Center District

7.2/10

Good

(183)

"The location was convenient and the price was very good. "

CA $72

CA $85 total

includes taxes & fees

Oct 5 - Oct 6

[](https://www.expedia.ca/San-Antonio-Hotels-Studio-6-San-Antonio.h83405963.Hotel-Information)

![1 bedroom, desk, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/1000000/60000/51000/50914/cabe2252.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, coffee/tea maker, dining tables](https://images.trvl-media.com/lodging/1000000/60000/51000/50914/c7209e52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/1000000/60000/51000/50914/07a845c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/1000000/60000/51000/50914/5ab5a9dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Studio 6 San Antonio, TX - Medical Center

Medical Center District

6.6/10

(754)

"The staff is great! Customer service is their forefront!"

CA $71

CA $87 total

includes taxes & fees

Oct 5 - Oct 6

[](https://www.expedia.ca/San-Antonio-Hotels-Studio-6-San-Antonio.h50914.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/700000/692600/692534/09358142.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/700000/692600/692534/e974d0cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/700000/692600/692534/bcf9766f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/1000000/700000/692600/692534/6d7e3cbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### OYO Inn & Suites Medical Center San Antonio

Medical Center District

7.2/10

Good

(218)

"Always great stay"

CA $75

CA $97 total

includes taxes & fees

Oct 7 - Oct 8

[](https://www.expedia.ca/San-Antonio-Hotels-OYO-Inn-Suites-Medical-Center-San-Antonio.h692534.Hotel-Information)

![Basic Room, Multiple Beds, Non Smoking](https://images.trvl-media.com/lodging/76000000/75220000/75211700/75211602/2a175bf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/76000000/75220000/75211700/75211602/00bf65b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/76000000/75220000/75211700/75211602/52d716c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/76000000/75220000/75211700/75211602/53fea236.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Flex Studios

Medical Center District

6.0/10

(485)

"Staff was helpful checking in"

CA $61

CA $72 total

includes taxes & fees

Oct 5 - Oct 6

[](https://www.expedia.ca/San-Antonio-Hotels-Flex-Studios.h75211602.Hotel-Information)

![Water park](https://images.trvl-media.com/lodging/2000000/1120000/1113200/1113168/5058d5ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fireplace](https://images.trvl-media.com/lodging/2000000/1120000/1113200/1113168/4657a7fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/2000000/1120000/1113200/1113168/bdb1061e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/2000000/1120000/1113200/1113168/afa62b6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Far West Side, 11.3 km from Medical Center District

9.0/10

Wonderful

(1089)

"Great family friendly resort"

CA $117

CA $196 total

includes taxes & fees

Oct 27 - Oct 28

[](https://www.expedia.ca/San-Antonio-Hotels-Hyatt-Vacation-Club-At-Wild-Oak-Ranch.h1113168.Hotel-Information)

![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654325/a85730af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654325/0b5b7b15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654325/5f5807c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654325/507bc31c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Courtyard by Marriott San Antonio SeaWorld - Westover Hills

Far West Side, 12.1 km from Medical Center District

8.6/10

Excellent

(1004)

"Will stay there again!"

CA $135

CA $160 total

includes taxes & fees

Oct 12 - Oct 13

[](https://www.expedia.ca/San-Antonio-Hotels-Courtyard-By-Marriott-San-Antonio-SeaWorld-Westover-Hills.h2654325.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/3000000/2320000/2319500/2319424/06cad791.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily full breakfast](https://images.trvl-media.com/lodging/3000000/2320000/2319500/2319424/1276751c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/3000000/2320000/2319500/2319424/18a616c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2320000/2319500/2319424/19bfe972.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham San Antonio Northwest

Far West Side, 10.4 km from Medical Center District

8.8/10

Excellent

(1001)

"We have stayed before, and prefer this hotel and location"

CA $114

CA $133 total

includes taxes & fees

Oct 6 - Oct 7

[](https://www.expedia.ca/San-Antonio-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Antonio-Northwest.h2319424.Hotel-Information)

![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/3200/3187/b99867e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/1000000/10000/3200/3187/4baf38da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/10000/3200/3187/533974de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily buffet breakfast (USD 18.95 per person)](https://images.trvl-media.com/lodging/1000000/10000/3200/3187/f65c9ef3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Westin San Antonio North

3.4 km from Medical Center District

8.6/10

Excellent

(1098)

"Great place to stay."

CA $120

CA $144 total

includes taxes & fees

Oct 5 - Oct 6

[](https://www.expedia.ca/San-Antonio-Hotels-Omni-San-Antonio-Hotel-At-The-Colonnade.h3187.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/920000/918400/918329/9da79e0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/920000/918400/918329/6a5e6a8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/920000/918400/918329/8fdf5f65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/920000/918400/918329/42882466.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Days Inn by Wyndham Suites San Antonio North/Stone Oak

14.7 km from Medical Center District

8.0/10

Very good

(1009)

"Nice quiet stay"

CA $74

CA $86 total

includes taxes & fees

Oct 6 - Oct 7

[](https://www.expedia.ca/San-Antonio-Hotels-Days-Inn-By-Wyndham-Suites-San-Antonio-NorthStone-Oak.h918329.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/110000000/109060000/109052800/109052763/5fbb5d5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/110000000/109060000/109052800/109052763/2717104d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/110000000/109060000/109052800/109052763/41c45dbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/110000000/109060000/109052800/109052763/c17e450c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites By Wyndham San Antonio At The Rim

11.9 km from Medical Center District

9.2/10

Wonderful

(651)

"I had a very nice stay."

CA $111

CA $130 total

includes taxes & fees

Oct 5 - Oct 6

[](https://www.expedia.ca/San-Antonio-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Antonio-At-The-Rim.h109052763.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-16&endDate=2025-10-17&regionId=553248635978913844&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Where to stay in Medical Center District

Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. [Learn more about Medical Center District](https://www.expedia.ca/San-Antonio-Medical-Center-District.dx553248635978913844)

-   Downtown San Antonio
-   Uptown
-   Far West Side
-   Stone Oak
-   Fort Sam Houston

![Downtown - Riverwalk showing heritage architecture, boating and a river or creek](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/34000/34785-San-Antonio-Rverwalk.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Downtown - Riverwalk which includes signage](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/34000/34789-San-Antonio-Rverwalk.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/34000/34793-San-Antonio-Rverwalk.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Downtown - Riverwalk which includes a bridge, boating and a river or creek](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/34000/34788-San-Antonio-Rverwalk.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Downtown - Riverwalk featuring signage](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/34000/34784-San-Antonio-Rverwalk.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=800120)

![Downtown San Antonio map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7BrmrDhqgxQ%7Bu%40iUe%60%40ia%40y%7EAmMkRgUqOad%40wPg%5CT%7DPdJmc%40xQElH%60CrZlR%7EIgDjNP%40uP%60h%40Lph%40a%40pQtLzb%40bFvIXdg%40mPxE%60R%7BK%60%7CAaAd%7EAoc%40dA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=MrJYQcM0zScwTbFLNWRMNBwAkbU=)

### Downtown San Antonio

Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=800120)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/535000/535610-marion-koogler-mcnay-art-museum.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/7/e1d88395fab384c9da8e4f446fd0d1af.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/7/1ccf5813987124aae8b2733223be9980.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/7/d6a1fc2a2d41cda288ee6c8c08223f50.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/7/e1537e371b4724babfe99cc04c237c59.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=553248635974902947)

![Uptown map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:ydesDviexQgd%40qGeaDglA%7BiAuZssAq%5Cof%40aLcgCoh%40wHeEx%5C_fB%60YwpB%7BMooG%7B%40%7D_DlF%7BZhHuIbgCm%7DAdJvIjUpGzM%7EMhHha%40nFrG%60YePfWmEbYcPlF%3FhHxKdJvg%40%7CZ%7Cx%40%7Cv%40p_BzKhXfLrPlb%40xXzi%40tIn%60%40dn%40rDhRz%40%7C%7DDlFdAfW%7BK%7EpA%3FxOsVjUnEzMsGjU%3FdoA%7Ci%40hHtIrDvXfH%7EMz%40dhB%7CM%7EMz%40ha%40%3Fj_AmF%60Nx%40bhBqDlEs%7BIbA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=5KRstSuCMr_zi7kxfgawsn-yfVM=)

### Uptown

While visiting Uptown, you might make a stop by sights like Marion Koogler McNay Art Museum and Alamo Quarry Market.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635974902947)

![](https://mediaim.expedia.com/destination/1/32d4867af6fd75a081e8873eb60c7c86.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/7/de4a14f44a07adb09a04d4f3a6ed958b.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/7/2782b57f65e40f8117efdcba283b180c.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/7/65cef24b374b47d9a0b3e7c06b383b4d.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/7/72c602606e17eb141df55e37cdf0e982.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=553248635975749416)

![Far West Side map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:_fyrDb%7EwyQmpLsbDyqCo%7B%40d%7BAi%7EDbJih%40ukAsa%40mp%40yr%40raBofBxZaj%40xfAeu%40bn%40uRtf%40y%5DpqAwr%40%7ChAg%60B%7CKqLlOyd%40xKhZp%7DAbzArdEheDrUxOfQpDlzDl%40%7EWfbAn%5DblAph%40bnD%7EX%7EgBjPviDmpJzf%40ekDbr%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=0B8LmRpUWiEUXggVgWiKS7L07-c=)

### Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635975749416)

![](https://mediaim.expedia.com/destination/7/9760dd0925b019876b814e4b83fc0d02.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=6343068)

![Stone Oak map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:qg_tDfmixQqXq_Mx%60I%7EuBmHzl%40vObfEmiB%60eAcdEnM&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=S1oBhJpmo5OYXFc5vi-iyXqubu4=)

### Stone Oak

Travelers come to Stone Oak for its abundant dining options, and you can see top attractions like Shops at Hardy Oak and Alta Vista while you're in town.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=6343068)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=6127453)

![Fort Sam Houston map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:e%7DurDrd%60xQiBEa%40i%40kAgGmAs%40oAtBx%40vAgCf%40EyVcMNQrCgH%3FClN%7BBwABue%40iR%3FDm%5Df%40o%40Og%5B_a%40gG%7DBcBo%40gDoK_ByI_%40%7DApB%7B%40ZoPLCsXsA_G%3F%7DGjU%3F%5CXt%40%5D%7EI%40Mc%40v%40u%40g%40q%40%7DBcMyIySmI_FetAim%40Y_A%7D%40EoRyIsC%7BCEc%7B%40pS%3F%40wMnQEDg%5Cdj%40DfFdGb%40rAnAPJyAbAb%40%7ERH%60%40x%40Ji%5Ed%40aBvA%5Bbl%40bVvElDzAbDJhsAtAvDtFvJ%7CJzIzJzMz_Alk%40xAvF%60AvH%7BBd%40qFvDwBmEqN%7CGCtP%5BA%3FfDW%3FVl_%40zSG%40lX%3FhI_IJBby%40_IJ%40tU&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=NZ0aks-nXJp-f0G8uQibgJiLtyQ=)

### Fort Sam Houston

One reason travelers love spending time in Fort Sam Houston is the stunning river views, and United States Army Medical Department Museum is a top place to visit.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=6127453)

## Top Medical Center District Hotel Reviews

![Hyatt Vacation Club at Wild Oak Ranch, San Antonio](//images.trvl-media.com/lodging/2000000/1120000/1113200/1113168/5058d5ba_y.jpg)

### Hyatt Vacation Club at Wild Oak Ranch, San Antonio

10/10 Excellent

"Wonderful lazy river "

[](https://expedia.ca/San-Antonio-Hotels-Hyatt-Vacation-Club-At-Wild-Oak-Ranch.h1113168.Hotel-Information)

![Hyatt Regency San Antonio Riverwalk](//images.trvl-media.com/lodging/1000000/20000/10700/10636/93e4ec15_y.jpg)

### Hyatt Regency San Antonio Riverwalk

10/10 Excellent

"Great "

[](https://expedia.ca/San-Antonio-Hotels-Hyatt-Regency-San-Antonio-Riverwalk.h10636.Hotel-Information)

![The Westin San Antonio North](//images.trvl-media.com/lodging/1000000/10000/3200/3187/b99867e6_y.jpg)

### The Westin San Antonio North

10/10 Excellent

"It was a great property. The staff was very polite not all of them but them. The room was great. Everything was very clean. We liked that there was an indoor pool and an outdoor purple. They have frozen yogurt. It’s a very family friendly. They even have a gym and a sauna. The only thing we didn’t like was that they charge for parking."

[](https://expedia.ca/San-Antonio-Hotels-Omni-San-Antonio-Hotel-At-The-Colonnade.h3187.Hotel-Information)

![Hotel Valencia Riverwalk](//images.trvl-media.com/lodging/1000000/900000/897400/897388/2b6d39b3_y.jpg)

### Hotel Valencia Riverwalk

10/10 Excellent

"The hotel was very stunning 😍 "

[](https://expedia.ca/San-Antonio-Hotels-Hotel-Valencia-Riverwalk.h897388.Hotel-Information)

![Riverwalk Plaza](//images.trvl-media.com/lodging/1000000/290000/288400/288321/ef3ca433_y.jpg)

### Riverwalk Plaza

10/10 Excellent

"Lots of shops nearby, was convenient to the event I was attending at the convention center. Good food at the gavel restaurant 😋 "

[](https://expedia.ca/San-Antonio-Hotels-Riverwalk-Plaza.h288321.Hotel-Information)

![Omni La Mansion del Rio](//images.trvl-media.com/lodging/1000000/20000/17400/17329/1aaa0955_y.jpg)

### Omni La Mansion del Rio

10/10 Excellent

"Right on River walk "

[](https://expedia.ca/San-Antonio-Hotels-Omni-La-Mansion-Del-Rio.h17329.Hotel-Information)

![Drury Plaza Hotel San Antonio Riverwalk](//images.trvl-media.com/lodging/2000000/1540000/1534300/1534252/232ec435_y.jpg)

### Drury Plaza Hotel San Antonio Riverwalk

10/10 Excellent

"An excellent place to stay, outstanding location and breakfast menu! Very clean and quiet!"

[](https://expedia.ca/San-Antonio-Hotels-Drury-Plaza-Hotel-San-Antonio-Riverwalk.h1534252.Hotel-Information)

![Menger Hotel](//images.trvl-media.com/lodging/1000000/10000/5900/5877/ae1a8ff6_y.jpg)

### Menger Hotel

10/10 Excellent

"Really interesting historical property. Antiques and historical artifacts everywhere. Would stay again."

[](https://expedia.ca/San-Antonio-Hotels-Menger-Hotel.h5877.Hotel-Information)

![Sonesta ES Suites San Antonio Downtown Alamo Plaza](//images.trvl-media.com/lodging/1000000/50000/41200/41122/11513eda_y.jpg)

### Sonesta ES Suites San Antonio Downtown Alamo Plaza

10/10 Excellent

"The room was spacious and clean. Loce the kitchenette and fridge in the room. Rivercity mall is about a 7 min walk which you can go through to access the riverwalk. The hotel Valet parking is convenient and easy, free breakfast included with stay "

[](https://expedia.ca/San-Antonio-Hotels-Sonesta-ES-Suites-San-Antonio-Downtown.h41122.Hotel-Information)

## Frequently asked questions

### What are the best hotels in Medical Center District that travellers recommend?

> [Drury Inn & Suites San Antonio Northwest Medical Center](https://www.expedia.ca/San-Antonio-Hotels-Drury-Inn-Suites-San-Antonio-Northwest-Medical-Center.h59226.Hotel-Information) is a great choice for travellers, earning an impressive review score of 9.2. This hotel not only offers a complimentary buffet breakfast to kickstart your day but also features an inviting indoor pool and hot tub, superb for unwinding after a day of exploring. Families will appreciate the convenience of kitchen facilities and free cribs, making it easier to accommodate little ones.
> 
>   
> 
> For those seeking a spacious stay, the [SpringHill Suites by Marriott San Antonio Medical Center/NW](https://www.expedia.ca/San-Antonio-Hotels-SpringHill-Suites-By-Marriott-San-Antonio-Medical-CenterNW.h40467.Hotel-Information), rated 8.8, provides comfortable suites that are ideal for families or couples. Guests love the option of a free to-go breakfast and an outdoor pool for afternoon relaxation. With shopping nearby and a 24-hour fitness centre, this hotel caters well to both leisure and active travellers.
> 
>   
> 
> [La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW](https://www.expedia.ca/San-Antonio-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Antonio-Medical-Ctr-NW.h1613977.Hotel-Information), boasting a review score of 8.6, is another excellent option, especially for families. It features both indoor and outdoor pools, along with convenient kitchen amenities. The proximity to a shopping district adds to the appeal, allowing for easy outings with the family.
> 
>   
> 
> Business travellers will find [Courtyard by Marriott Medical Center San Antonio](https://www.expedia.ca/San-Antonio-Hotels-Courtyard-By-Marriott-Medical-Center-San-Antonio.h12556.Hotel-Information) appealing, rated 8.6. This hotel offers multiple meeting rooms, a 24-hour business centre, and free Wi-Fi in rooms, ensuring productivity during your stay. With an outdoor pool and accessible fitness facilities, it's a great blend of work and relaxation.
> 
>   
> 
> For a blend of comfort and family-friendly amenities, [San Antonio Marriott Northwest Medical Center](https://www.expedia.ca/San-Antonio-Hotels-San-Antonio-Marriott-Northwest.h4192.Hotel-Information), rated 8.4, provides an friendly space with an outdoor pool and spacious rooms equipped with balconies. The hotel's design caters to both leisure and business guests, making it a versatile choice for various travellers.

### What are the best family hotels in Medical Center District?

> [Drury Inn & Suites San Antonio Northwest Medical Center](https://www.expedia.ca/San-Antonio-Hotels-Drury-Inn-Suites-San-Antonio-Northwest-Medical-Center.h59226.Hotel-Information) is an excellent choice for families seeking comfort and convenience, boasting an impressive review score of 9.2. Families can enjoy spacious connecting rooms, ensuring everyone has plenty of space to relax. Plus, the hotel offers complimentary cribs and a sofa bed, making it easy to accommodate little ones. Guests rave about the delicious free buffet breakfast that fuels a day of exploration.
> 
>   
> 
> Another fantastic option is the [Fairfield Inn & Suites by Marriott San Antonio Medical Center](https://www.expedia.ca/San-Antonio-Hotels-Fairfield-Inn-Suites-By-Marriott-San-Antonio-Medical-Center.h68847371.Hotel-Information), which scores a solid 9.0. This hotel not only features a refreshing pool great for family fun, but it also provides rollaway beds at no extra charge. With connecting rooms and free cribs available, it's tailored for families with young children. The complimentary breakfast is a great way to start your day before heading out to nearby attractions.
> 
>   
> 
> For those looking for a bit more space, [SpringHill Suites by Marriott San Antonio Medical Center/NW](https://www.expedia.ca/San-Antonio-Hotels-SpringHill-Suites-By-Marriott-San-Antonio-Medical-CenterNW.h40467.Hotel-Information), rated 8.8, has features friendly for families such as a pool and sofa beds. The hotel also provides free cribs and a nearby theme park, ensuring that your family can enjoy both relaxation and adventure during your stay. Guests appreciate the daily housekeeping and snack bar, which add convenience to your family vacation.
> 
>   
> 
> [La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW](https://www.expedia.ca/San-Antonio-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Antonio-Medical-Ctr-NW.h1613977.Hotel-Information) is another family-friendly gem, with a review score of 8.6. This hotel features a pool and offers free cribs, making it accessible for families with babies. The connecting rooms and free meals for children further enhance its appeal. Guests love the gardens for some outdoor family time and the proximity to theme parks for thrilling adventures.
> 
>   
> 
> Lastly, [Courtyard by Marriott Medical Center San Antonio](https://www.expedia.ca/San-Antonio-Hotels-Courtyard-By-Marriott-Medical-Center-San-Antonio.h12556.Hotel-Information), also with a score of 8.6, rounds out the list of great family hotels. With features like connecting rooms, sofa beds, and a pool, it provides ample space for families. The availability of kids' meals and a nearby theme park makes it an attractive option for those traveling with children.

### What hotels in Medical Center District offer free breakfast?

> [Drury Inn & Suites San Antonio Northwest Medical Center](https://www.expedia.ca/San-Antonio-Hotels-Drury-Inn-Suites-San-Antonio-Northwest-Medical-Center.h59226.Hotel-Information) is a fantastic choice for travellers looking for a family-friendly atmosphere in the Medical Centre District. This hotel boasts a free buffet breakfast that guests rave about, ensuring a great start to the day. Additionally, families can take advantage of the indoor pool and hot tub, providing a great place for relaxation and fun. With a customer review rating of 9.2, it's clear that many guests appreciate the quality and convenience of this property.
> 
>   
> 
> Another excellent option is the [Fairfield Inn & Suites by Marriott San Antonio Medical Center](https://www.expedia.ca/San-Antonio-Hotels-Fairfield-Inn-Suites-By-Marriott-San-Antonio-Medical-Center.h68847371.Hotel-Information), which also offers a complimentary breakfast, including options on weekends. This hotel features a pool and spacious suites that are ideal for families needing extra room. With a customer review score of 9.0, it's highly rated for its comfortable accommodations and friendly service.
> 
>   
> 
> For those traveling without children or couples seeking a romantic getaway, the [SpringHill Suites by Marriott San Antonio Medical Center/NW](https://www.expedia.ca/San-Antonio-Hotels-SpringHill-Suites-By-Marriott-San-Antonio-Medical-CenterNW.h40467.Hotel-Information) offers a blend of comfort and convenience. Their outdoor pool and fitness centre cater to guests looking to unwind or maintain their routine during their stay.
> 
>   
> 
> Each of these properties provides a welcoming environment, ensuring both families and couples can find the great home base during their San Antonio adventure.

### What are the best budget hotels in Medical Center District?

> [Drury Inn & Suites San Antonio Northwest Medical Center](https://www.expedia.ca/San-Antonio-Hotels-Drury-Inn-Suites-San-Antonio-Northwest-Medical-Center.h59226.Hotel-Information) is a fantastic option for budget-conscious families seeking comfort and convenience. Rated 9.2 by guests, this hotel offers an array of family-friendly amenities, including a complimentary breakfast and a cozy indoor pool great for splashing around after a day of exploring. The spacious rooms, equipped with kitchen facilities and sofa beds, ensure that everyone has a comfortable place to unwind.
> 
>   
> 
> Another excellent choice is the [Fairfield Inn & Suites by Marriott San Antonio Medical Center](https://www.expedia.ca/San-Antonio-Hotels-Fairfield-Inn-Suites-By-Marriott-San-Antonio-Medical-Center.h68847371.Hotel-Information), boasting a review score of 9.0. Families will appreciate the free weekend breakfast, secure self-parking, and the inviting pool area. The hotel's traditional design and accessible features cater to a wide range of travellers, making it an excellent base for both families and couples looking for a relaxing getaway.
> 
>   
> 
> For travellers seeking a more business-oriented experience, properties like the [Courtyard by Marriott Medical Center San Antonio](https://www.expedia.ca/San-Antonio-Hotels-Courtyard-By-Marriott-Medical-Center-San-Antonio.h12556.Hotel-Information) and [SpringHill Suites by Marriott San Antonio Medical Center/NW](https://www.expedia.ca/San-Antonio-Hotels-SpringHill-Suites-By-Marriott-San-Antonio-Medical-CenterNW.h40467.Hotel-Information) can accommodate your needs greatly. While they offer family-friendly amenities, their business centres and fitness facilities make them ideal for business travellers or couples looking to fit in some exercise during their stay. With such a variety of options, you're sure to find the great budget hotel in the Medical Centre District.

### Can I cancel my hotel reservation on Expedia?

> Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Medical Center District hotel for you.

### How can I save on a Medical Center District hotel booking with Expedia?

> Before booking your Medical Center District hotel, remember to join Expedia's free travel rewards program. Just sign up and sign in to access our lowest Member Prices as well as members-only perks. You could also enjoy savings by bundling together your hotel and flights on Expedia.

### How much is the nightly rate at a Medical Center District hotel?

> Hotel prices in Medical Center District often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

## Explore a world of travel with Expedia

-   Lodging
-   Flights
-   Packages
-   Cars
-   More ways to book

-   [3 Star Hotels in Woodridge](https://www.expedia.ca/3Star-Woodridge-San-Antonio-Hotels.s30-n553248635976386203-0.Travel-Guide-Filter-Hotels)
-   [5 Star Hotels in Northwest Side](https://www.expedia.ca/5Star-Northwest-Side-San-Antonio-Hotels.s50-n887264728595001344-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Alamo Quarry Market](https://www.expedia.ca/Alamo-Quarry-Market-Hotels.0-l6163147-0.Travel-Guide-Filter-Hotels)
-   [Babcock North Hotels](https://www.expedia.ca/Babcock-North-San-Antonio-Hotels.0-n553248635976474646-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Bandera Road Community Church](https://www.expedia.ca/Bandera-Road-Community-Church-Hotels.0-l553248621532643314-0.Travel-Guide-Filter-Hotels)
-   [Motel 6 Hotels in Beacon Hill](https://www.expedia.ca/Beacon-Hill-San-Antonio-Hotels-Motel-6.0-n553248635976470722-0--bMotel6.Travel-Guide-Filter-Hotels)
-   [Beacon Hill Hotels](https://www.expedia.ca/Beacon-Hill-San-Antonio-Hotels.0-n553248635976470722-0.Travel-Guide-Filter-Hotels)
-   [Independent Hotels in Braun Hollow](https://www.expedia.ca/Braun-Hollow-San-Antonio-Hotels-Independent.0-n553248635976471791-0--bIndependent.Travel-Guide-Filter-Hotels)
-   [Hotels near CHRISTUS Santa Rosa Hospital - Medical Center](https://www.expedia.ca/CHRISTUS-Santa-Rosa-Hospital-Medical-Center-Hotels.0-l553248621593511347-0.Travel-Guide-Filter-Hotels)
-   [Castle Hills Hotels](https://www.expedia.ca/Castle-Hills-San-Antonio-Hotels.0-n553248634999005679-0.Travel-Guide-Filter-Hotels)
-   [Omni Hotels in Crown Meadows](https://www.expedia.ca/Crown-Meadows-San-Antonio-Hotels-Omni.0-n553248635976469800-0--bOmni.Travel-Guide-Filter-Hotels)
-   [Crown Meadows Hotels](https://www.expedia.ca/Crown-Meadows-San-Antonio-Hotels.0-n553248635976469800-0.Travel-Guide-Filter-Hotels)
-   [Crownhill Park Hotels](https://www.expedia.ca/Crownhill-Park-San-Antonio-Hotels.0-n553248635976472972-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Dellview Park](https://www.expedia.ca/Dellview-Park-Hotels.0-l6229159-0.Travel-Guide-Filter-Hotels)
-   [Best Western Hotels in Edison](https://www.expedia.ca/Edison-San-Antonio-Hotels-Best-Western.0-n553248635976468869-0--bBestWestern.Travel-Guide-Filter-Hotels)
-   [Great Northwest Hotels](https://www.expedia.ca/Great-Northwest-San-Antonio-Hotels.0-n553248635976481542-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Huebner Oaks](https://www.expedia.ca/Huebner-Oaks-Hotels.0-l6230811-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Ingram Park Mall](https://www.expedia.ca/Ingram-Park-Mall-Hotels.0-l6229144-0.Travel-Guide-Filter-Hotels)
-   [Oyo Rooms Hotels in Jade Oaks](https://www.expedia.ca/Jade-Oaks-San-Antonio-Hotels-OYO-Rooms.0-n553248635976384547-0--bOYORooms.Travel-Guide-Filter-Hotels)
-   [Jade Oaks Hotels](https://www.expedia.ca/Jade-Oaks-San-Antonio-Hotels.0-n553248635976384547-0.Travel-Guide-Filter-Hotels)
-   [Cheap Hotels in Jefferson](https://www.expedia.ca/Jefferson-San-Antonio-Hotels-Cheap-Hotels.0-n553248635976480676-0-tCheapHotels.Travel-Guide-Filter-Hotels)
-   [Historic Hotels in Jefferson](https://www.expedia.ca/Jefferson-San-Antonio-Hotels-Historic-Hotel.0-n553248635976480676-0-tHistoricHotel.Travel-Guide-Filter-Hotels)
-   [Hotels with Hot Tubs in Jefferson](https://www.expedia.ca/Jefferson-San-Antonio-Hotels-Hotels-With-Hot-Tubs.0-n553248635976480676-0-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels)
-   [Luxury Hotels in Jefferson](https://www.expedia.ca/Jefferson-San-Antonio-Hotels-Luxury-Hotel.0-n553248635976480676-0-tLuxuryHotel.Travel-Guide-Filter-Hotels)
-   [Leon Valley Hotels](https://www.expedia.ca/Leon-Valley-San-Antonio-Hotels.0-n125419-0.Travel-Guide-Filter-Hotels)
-   [Hotels with smoking rooms in Midtown](https://www.expedia.ca/Midtown-San-Antonio-Hotels-Hotels-With-Smoking-Rooms.0-n553248633938969302-0-tHotelswithsmokingrooms.Travel-Guide-Filter-Hotels)
-   [Pet-Friendly Hotels in Midtown](https://www.expedia.ca/Midtown-San-Antonio-Hotels-Pet-Friendly-Hotel.0-n553248633938969302-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels)
-   [Scuba Diving Hotels in Midtown](https://www.expedia.ca/Midtown-San-Antonio-Hotels-Scuba-Diving-Vacations.0-n553248633938969302-0-tscubadivingvacations.Travel-Guide-Filter-Hotels)
-   [Waterpark Hotels in Midtown](https://www.expedia.ca/Midtown-San-Antonio-Hotels-Waterpark-Hotels.0-n553248633938969302-0-tWaterparkHotels.Travel-Guide-Filter-Hotels)
-   [Hotels near Monster Mini Golf](https://www.expedia.ca/Monster-Mini-Golf-Hotels.0-l553248621532643386-0.Travel-Guide-Filter-Hotels)
-   [Hotels with smoking rooms in North Central](https://www.expedia.ca/North-Central-San-Antonio-Hotels-Hotels-With-Smoking-Rooms.0-n3000663370-0-tHotelswithsmokingrooms.Travel-Guide-Filter-Hotels)
-   [North Central Hotels](https://www.expedia.ca/North-Central-San-Antonio-Hotels.0-n3000663370-0.Travel-Guide-Filter-Hotels)
-   [Hotels near North Star Mall](https://www.expedia.ca/North-Star-Mall-Hotels.0-l502628-0.Travel-Guide-Filter-Hotels)
-   [Best Western Hotels in Northwest Crossing](https://www.expedia.ca/Northwest-Crossing-San-Antonio-Hotels-Best-Western.0-n553248635976477588-0--bBestWestern.Travel-Guide-Filter-Hotels)
-   [Golf Hotels in Northwest Los Angeles Heights](https://www.expedia.ca/Northwest-Los-Angeles-Heights-San-Antonio-Hotels-Golf-Hotel.0-n553248635976480994-0-tGolfHotel.Travel-Guide-Filter-Hotels)
-   [Hotels with Free Parking in Northwest Los Angeles Heights](https://www.expedia.ca/Northwest-Los-Angeles-Heights-San-Antonio-Hotels-Hotels-With-Free-Parking.0-n553248635976480994-0-tHotelswithFreeParking.Travel-Guide-Filter-Hotels)
-   [Hotels with an Indoor Pool in Northwest Los Angeles Heights](https://www.expedia.ca/Northwest-Los-Angeles-Heights-San-Antonio-Hotels-Hotels-With-Indoor-Pool.0-n553248635976480994-0-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels)
-   [Pet-Friendly Hotels in Northwest Los Angeles Heights](https://www.expedia.ca/Northwest-Los-Angeles-Heights-San-Antonio-Hotels-Pet-Friendly-Hotel.0-n553248635976480994-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels)
-   [Cheap Hotels in Northwest Side](https://www.expedia.ca/Northwest-Side-San-Antonio-Hotels-Cheap-Hotels.0-n887264728595001344-0-tCheapHotels.Travel-Guide-Filter-Hotels)
-   [Family Hotels in Northwest Side](https://www.expedia.ca/Northwest-Side-San-Antonio-Hotels-Family-Hotel.0-n887264728595001344-0-tFamilyHotel.Travel-Guide-Filter-Hotels)
-   [Hotels with Free Airport Shuttle in Northwest Side](https://www.expedia.ca/Northwest-Side-San-Antonio-Hotels-Hotels-With-Free-Airport-Shuttle.0-n887264728595001344-0-tHotelswithFreeAirportShuttle.Travel-Guide-Filter-Hotels)
-   [Hotels with Kitchenettes in Northwest Side](https://www.expedia.ca/Northwest-Side-San-Antonio-Hotels-Hotels-With-Kitchenettes.0-n887264728595001344-0-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels)
-   [Pet-Friendly Hotels in Northwest Side](https://www.expedia.ca/Northwest-Side-San-Antonio-Hotels-Pet-Friendly-Hotel.0-n887264728595001344-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels)
-   [Spa Hotels in Northwest Side](https://www.expedia.ca/Northwest-Side-San-Antonio-Hotels-Spa-Hotel.0-n887264728595001344-0-tSpaHotel.Travel-Guide-Filter-Hotels)
-   [Hotels near Oak Hills Country Club](https://www.expedia.ca/Oak-Hills-Country-Club-Hotels.0-l553248621532643653-0.Travel-Guide-Filter-Hotels)
-   [Boutique Hotels in Oakland Estates](https://www.expedia.ca/Oakland-Estates-San-Antonio-Hotels-Boutique-Hotel.0-n6230858-0-tBoutiqueHotel.Travel-Guide-Filter-Hotels)
-   [Hotels with Early Check-in in Oakland Estates](https://www.expedia.ca/Oakland-Estates-San-Antonio-Hotels-Hotel-With-Early-Check-In.0-n6230858-0-thotelwithearlycheckin.Travel-Guide-Filter-Hotels)
-   [Romantic Hotels in Oakland Estates](https://www.expedia.ca/Oakland-Estates-San-Antonio-Hotels-Romantic-Hotel.0-n6230858-0-tRomanticHotel.Travel-Guide-Filter-Hotels)
-   [Spa Hotels in Oakland Estates](https://www.expedia.ca/Oakland-Estates-San-Antonio-Hotels-Spa-Hotel.0-n6230858-0-tSpaHotel.Travel-Guide-Filter-Hotels)
-   [Waterpark Hotels in Oakland Estates](https://www.expedia.ca/Oakland-Estates-San-Antonio-Hotels-Waterpark-Hotels.0-n6230858-0-tWaterparkHotels.Travel-Guide-Filter-Hotels)
-   [Olmos Park Terrace Hotels](https://www.expedia.ca/Olmos-Park-Terrace-San-Antonio-Hotels.0-n553248635976469841-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Phil Hardberger Park](https://www.expedia.ca/Phil-Hardberger-Park-Hotels.0-l553248621532643389-0.Travel-Guide-Filter-Hotels)
-   [Pet-Friendly Hotels in Prospect Hill](https://www.expedia.ca/Prospect-Hill-San-Antonio-Hotels-Pet-Friendly-Hotel.0-n553248635976387013-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels)
-   [San Antonio Hotels](https://www.expedia.ca/San-Antonio-Hotels.d178303.Travel-Guide-Hotels)
-   [Shavano Park Hotels](https://www.expedia.ca/Shavano-Park-San-Antonio-Hotels.0-n6004947-0.Travel-Guide-Filter-Hotels)
-   [Adults Only Resorts & in Shearer Hills - Ridgeview](https://www.expedia.ca/Shearer-Hills-Ridgeview-San-Antonio-Hotels-Adults-Only-Resorts.0-n553248635976471907-0-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels)
-   [Hotels near South Texas Medical Center](https://www.expedia.ca/South-Texas-Medical-Center-Hotels.0-l6193120-0.Travel-Guide-Filter-Hotels)
-   [Hotels near St. Mary's University](https://www.expedia.ca/St-Marys-University-Hotels.0-l502632-0.Travel-Guide-Filter-Hotels)
-   [Hotels near USAA Corporate Office Headquarters](https://www.expedia.ca/USAA-Corporate-Office-Headquarters-Hotels.0-l553248621593511346-0.Travel-Guide-Filter-Hotels)
-   [Hotels near University of Texas Health and Science Center at San Antonio](https://www.expedia.ca/University-Of-Texas-Health-And-Science-Center-At-San-Antonio-Hotels.0-l6191585-0.Travel-Guide-Filter-Hotels)
-   [All Inclusive Resorts and in Vance Jackson](https://www.expedia.ca/Vance-Jackson-San-Antonio-Hotels-All-Inclusive-Hotel.0-n553248635976480877-0-tAllInclusiveHotel.Travel-Guide-Filter-Hotels)
-   [Vance Jackson Hotels](https://www.expedia.ca/Vance-Jackson-San-Antonio-Hotels.0-n553248635976480877-0.Travel-Guide-Filter-Hotels)
-   [Vista Del Norte Hotels](https://www.expedia.ca/Vista-Del-Norte-San-Antonio-Hotels.0-n553248635976474068-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Wonderland of the Americas Mall](https://www.expedia.ca/Wonderland-Of-The-Americas-Mall-Hotels.0-l6127197-0.Travel-Guide-Filter-Hotels)
-   [Pet-Friendly Hotels in Woodlawn Lake](https://www.expedia.ca/Woodlawn-Lake-San-Antonio-Hotels-Pet-Friendly-Hotel.0-n553248635976476298-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels)
-   [Hotels near Woodlawn Theater](https://www.expedia.ca/Woodlawn-Theater-Hotels.0-l6083191-0.Travel-Guide-Filter-Hotels)
-   [Best Western Hotels in Woodridge](https://www.expedia.ca/Woodridge-San-Antonio-Hotels-Best-Western.0-n553248635976386203-0--bBestWestern.Travel-Guide-Filter-Hotels)

-   [Flights to San Antonio](https://www.expedia.ca/Cheap-Flights-To-San-Antonio.d178303.Travel-Guide-Flights)
-   [Flights from San Antonio Intl.](https://www.expedia.ca/lp/airports/sat/flights-from-san-antonio-intl-airport)
-   [Flights from Austin (AUS) to San Antonio (SAT)](https://www.expedia.ca/lp/flights/aus/sat/austin-to-san-antonio)
-   [Flights from Bellingham (BLI) to San Antonio (SAT)](https://www.expedia.ca/lp/flights/bli/sat/bellingham-to-san-antonio)
-   [Flights from Buffalo (BUF) to San Antonio (SAT)](https://www.expedia.ca/lp/flights/buf/sat/buffalo-to-san-antonio)
-   [Flights from Dallas (DFW) to San Antonio (SAT)](https://www.expedia.ca/lp/flights/dfw/sat/dallas-to-san-antonio)
-   [Flights from Detroit (DTW) to San Antonio (SAT)](https://www.expedia.ca/lp/flights/dtw/sat/detroit-to-san-antonio)
-   [Flights from Houston (IAH) to San Antonio (SAT)](https://www.expedia.ca/lp/flights/iah/sat/houston-to-san-antonio)
-   [Flights from Los Angeles (LAX) to San Antonio (SAT)](https://www.expedia.ca/lp/flights/lax/sat/los-angeles-to-san-antonio)
-   [Flights from Midland (MAF) to San Antonio (SAT)](https://www.expedia.ca/lp/flights/maf/sat/midland-to-san-antonio)
-   [Flights from Phoenix (PHX) to San Antonio (SAT)](https://www.expedia.ca/lp/flights/phx/sat/phoenix-to-san-antonio)
-   [Flights from Seattle (SEA) to San Antonio (SAT)](https://www.expedia.ca/lp/flights/sea/sat/seattle-to-san-antonio)
-   [Flights from Edmonton (YEG) to San Antonio (SAT)](https://www.expedia.ca/lp/flights/yeg/sat/edmonton-to-san-antonio)
-   [Flights from Kelowna (YLW) to San Antonio (SAT)](https://www.expedia.ca/lp/flights/ylw/sat/kelowna-to-san-antonio)
-   [Flights from Ottawa (YOW) to San Antonio (SAT)](https://www.expedia.ca/lp/flights/yow/sat/ottawa-to-san-antonio)
-   [Flights from Grande Prairie (YQU) to San Antonio (SAT)](https://www.expedia.ca/lp/flights/yqu/sat/grande-prairie-to-san-antonio)
-   [Flights from Montreal (YUL) to San Antonio (SAT)](https://www.expedia.ca/lp/flights/yul/sat/montreal-to-san-antonio)
-   [Flights from Vancouver (YVR) to San Antonio (SAT)](https://www.expedia.ca/lp/flights/yvr/sat/vancouver-to-san-antonio)
-   [Flights from Winnipeg (YWG) to San Antonio (SAT)](https://www.expedia.ca/lp/flights/ywg/sat/winnipeg-to-san-antonio)
-   [Flights from Fort Saint John (YXJ) to San Antonio (SAT)](https://www.expedia.ca/lp/flights/yxj/sat/fort-saint-john-to-san-antonio)
-   [Flights from Calgary (YYC) to San Antonio (SAT)](https://www.expedia.ca/lp/flights/yyc/sat/calgary-to-san-antonio)
-   [Flights from Toronto (YYZ) to San Antonio (SAT)](https://www.expedia.ca/lp/flights/yyz/sat/toronto-to-san-antonio)

-   [North Star Mall](https://www.expedia.ca/North-Star-Mall-Uptown.d502628.Vacation-Attraction)
-   [Visit Balcones Heights](https://www.expedia.ca/San-Antonio-Balcones-Heights.dx553248634999172368)
-   [Visit Braun's Farm](https://www.expedia.ca/San-Antonio-Brauns-Farm.dx553248635976475762)
-   [Visit Castle Hills](https://www.expedia.ca/San-Antonio-Castle-Hills.dx553248634999005679)
-   [Visit Leon Valley](https://www.expedia.ca/San-Antonio-Leon-Valley.dx125419)
-   [Visit Oakland Estates](https://www.expedia.ca/San-Antonio-Oakland-Estates.dx6230858)
-   [San Pedro Springs Park](https://www.expedia.ca/San-Pedro-Springs-Park-Midtown.d553248621532643336.Vacation-Attraction)
-   [Usaa Corporate Office Headquarters](https://www.expedia.ca/USAA-Corporate-Office-Headquarters-Medical-Center-District.d553248621593511346.Vacation-Attraction)

-   [Rental cars San Antonio Intl. airport](https://www.expedia.ca/Car-Rentals-In-San-Antonio-Intl.d5521747.Car-Rental-Guide)
-   [Car rentals near Shavano Park](https://www.expedia.ca/Car-Rentals-In-Shavano-Park.d6004947.Car-Rental-Guide)
-   [Car rentals near USAA Corporate Office Headquarters](https://www.expedia.ca/Car-Rentals-In-USAA-Corporate-Office-Headquarters.d553248621593511346.Car-Rental-Guide)

-   [Book Hotels in Medical Center District on Expedia.com](https://www.expedia.com/Medical-Center-District-San-Antonio-Hotels.0-n553248635978913844-0.Travel-Guide-Filter-Hotels)

-   Explore a world of travel with Expedia

### Hotels in top San Antonio neighborhoods

-   [Hotels in Downtown San Antonio](https://expedia.ca/Downtown-San-Antonio-San-Antonio-Hotels.0-n800120-0.Travel-Guide-Filter-Hotels)
-   [Hotels in Uptown](https://expedia.ca/Uptown-San-Antonio-Hotels.0-n553248635974902947-0.Travel-Guide-Filter-Hotels)
-   [Hotels in Far West Side](https://expedia.ca/Far-West-Side-San-Antonio-Hotels.0-n553248635975749416-0.Travel-Guide-Filter-Hotels)
-   [Hotels in Medical Center District](https://expedia.ca/Medical-Center-District-San-Antonio-Hotels.0-n553248635978913844-0.Travel-Guide-Filter-Hotels)
-   [Hotels in Stone Oak](https://expedia.ca/Stone-Oak-San-Antonio-Hotels.0-n6343068-0.Travel-Guide-Filter-Hotels)
-   [Hotels in Fort Sam Houston](https://expedia.ca/Fort-Sam-Houston-San-Antonio-Hotels.0-n6127453-0.Travel-Guide-Filter-Hotels)
-   [Hotels in Northwest Side](https://expedia.ca/Northwest-Side-San-Antonio-Hotels.0-n887264728595001344-0.Travel-Guide-Filter-Hotels)
-   [Hotels in La Cantera District](https://expedia.ca/La-Cantera-District-San-Antonio-Hotels.0-n887254682616180736-0.Travel-Guide-Filter-Hotels)
-   [Hotels in Midtown](https://expedia.ca/Midtown-San-Antonio-Hotels.0-n553248633938969302-0.Travel-Guide-Filter-Hotels)
-   [Hotels in Arena District](https://expedia.ca/Arena-District-San-Antonio-Hotels.0-n553248635976384171-0.Travel-Guide-Filter-Hotels)
-   [Hotels in Near East Side](https://expedia.ca/Near-East-Side-San-Antonio-Hotels.0-n553248635976482249-0.Travel-Guide-Filter-Hotels)
-   [Hotels in South San Antonio](https://expedia.ca/South-San-Antonio-San-Antonio-Hotels.0-n6239233-0.Travel-Guide-Filter-Hotels)
-   [Hotels in Live Oak](https://expedia.ca/Live-Oak-San-Antonio-Hotels.0-n177652-0.Travel-Guide-Filter-Hotels)
-   [Hotels in Alamo Heights](https://expedia.ca/Alamo-Heights-San-Antonio-Hotels.0-n553248633938969296-0.Travel-Guide-Filter-Hotels)
-   [Hotels in Pearl District](https://expedia.ca/Pearl-District-San-Antonio-Hotels.0-n6163206-0.Travel-Guide-Filter-Hotels)
-   [Hotels in Tobin Hill](https://expedia.ca/Tobin-Hill-San-Antonio-Hotels.0-n553248635976386526-0.Travel-Guide-Filter-Hotels)
-   [Hotels in Lavaca](https://expedia.ca/Lavaca-San-Antonio-Hotels.0-n553248635976394887-0.Travel-Guide-Filter-Hotels)
-   [Hotels in Arsenal](https://expedia.ca/Arsenal-San-Antonio-Hotels.0-n553248635976470970-0.Travel-Guide-Filter-Hotels)
-   [Hotels in Dignowty Hill](https://expedia.ca/Dignowty-Hill-San-Antonio-Hotels.0-n553248635976387522-0.Travel-Guide-Filter-Hotels)
-   [Hotels in Denver Heights](https://expedia.ca/Denver-Heights-San-Antonio-Hotels.0-n553248635976470555-0.Travel-Guide-Filter-Hotels)

### Hotels near popular San Antonio Attractions

-   [Hotels near USAA Corporate Office Headquarters](https://expedia.ca/USAA-Corporate-Office-Headquarters-Hotels.0-l553248621593511346-0.Travel-Guide-Filter-Hotels)
-   [Hotels near South Texas Medical Center](https://expedia.ca/South-Texas-Medical-Center-Hotels.0-l6193120-0.Travel-Guide-Filter-Hotels)
-   [Hotels near University of Texas Health and Science Center at San Antonio](https://expedia.ca/University-Of-Texas-Health-And-Science-Center-At-San-Antonio-Hotels.0-l6191585-0.Travel-Guide-Filter-Hotels)
-   [Hotels near CHRISTUS Santa Rosa Hospital - Medical Center](https://expedia.ca/CHRISTUS-Santa-Rosa-Hospital-Medical-Center-Hotels.0-l553248621593511347-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Oak Hills Country Club](https://expedia.ca/Oak-Hills-Country-Club-Hotels.0-l553248621532643653-0.Travel-Guide-Filter-Hotels)
-   [Hotels near The San Antonio Art Institute](https://expedia.ca/The-San-Antonio-Art-Institute-Hotels.0-l553248621532643355-0.Travel-Guide-Filter-Hotels)
-   [Hotels near River Walk](https://expedia.ca/River-Walk-Hotels.0-l6125866-0.Travel-Guide-Filter-Hotels)

### More Accommodation Types in Medical Center District

-   [Vacation Homes in San Antonio](https://expedia.ca/San-Antonio-Private-Vacation-Homes.d178303-aaPrivateVacationHomes.Travel-Guide-Accommodation)
-   [Apartments in San Antonio](https://expedia.ca/San-Antonio-Apartments.d178303-aaApartments.Travel-Guide-Accommodation)
-   [Cottages in San Antonio](https://expedia.ca/San-Antonio-Cottages.d178303-aaCottages.Travel-Guide-Accommodation)
-   [Condo Rentals in San Antonio](https://expedia.ca/San-Antonio-Condos.d178303-aaCondos.Travel-Guide-Accommodation)
-   [Motels in San Antonio](https://expedia.ca/San-Antonio-Motels.d178303-aaMotels.Travel-Guide-Accommodation)
-   [Villas in San Antonio](https://expedia.ca/San-Antonio-Villas.d178303-aaVillas.Travel-Guide-Accommodation)
-   [Guest Houses in San Antonio](https://expedia.ca/San-Antonio-Guest-Houses.d178303-aaGuestHouses.Travel-Guide-Accommodation)
-   [Cabin Rentals in San Antonio](https://expedia.ca/San-Antonio-Cabins.d178303-aaCabins.Travel-Guide-Accommodation)
-   [Aparthotels in San Antonio](https://expedia.ca/San-Antonio-Apart-Hotels.d178303-aaApartHotels.Travel-Guide-Accommodation)
-   [Resorts in San Antonio](https://expedia.ca/San-Antonio-Resort-Hotels.d178303-aaResortHotels.Travel-Guide-Accommodation)
-   [B&B in San Antonio](https://expedia.ca/San-Antonio-Bed-And-Breakfast.d178303-aaBedAndBreakfast.Travel-Guide-Accommodation)
-   [Farmstay in San Antonio](https://expedia.ca/San-Antonio-Agritourism.d178303-aaAgritourism.Travel-Guide-Accommodation)
-   [RV Parks in San Antonio](https://expedia.ca/San-Antonio-RV-Parks.d178303-aaRVParks.Travel-Guide-Accommodation)
-   [Houseboats in San Antonio](https://expedia.ca/San-Antonio-Houseboats.d178303-aaHouseboats.Travel-Guide-Accommodation)
-   [Lodges in San Antonio](https://expedia.ca/San-Antonio-Lodges.d178303-aaLodges.Travel-Guide-Accommodation)
-   [Residences in San Antonio](https://expedia.ca/San-Antonio-Residences.d178303-aaResidences.Travel-Guide-Accommodation)
-   [Castles in San Antonio](https://expedia.ca/San-Antonio-Castles.d178303-aaCastles.Travel-Guide-Accommodation)
-   [Inns in San Antonio](https://expedia.ca/San-Antonio-Inns.d178303-aaInns.Travel-Guide-Accommodation)
-   [Ranches in San Antonio](https://expedia.ca/San-Antonio-Ranches.d178303-aaRanches.Travel-Guide-Accommodation)

### Hotels Close to Nearby Airports

-   [Hotels near San Antonio Intl. Airport](https://expedia.ca/San-Antonio-Intl-Airport-Hotels.0-aSAT-0.Travel-Guide-Filter-Hotels)

### Medical Center District Hotels by Star Rating

-   [2 Star Hotels in Medical Center District](https://expedia.ca/2Star-Medical-Center-District-San-Antonio-Hotels.s20-n553248635978913844-0.Travel-Guide-Filter-Hotels)
-   [3 Star Hotels in Medical Center District](https://expedia.ca/3Star-Medical-Center-District-San-Antonio-Hotels.s30-n553248635978913844-0.Travel-Guide-Filter-Hotels)
-   [4 Star Hotels in Medical Center District](https://expedia.ca/4Star-Medical-Center-District-San-Antonio-Hotels.s40-n553248635978913844-0.Travel-Guide-Filter-Hotels)
-   [5 Star Hotels in Medical Center District](https://expedia.ca/5Star-Medical-Center-District-San-Antonio-Hotels.s50-n553248635978913844-0.Travel-Guide-Filter-Hotels)

### Medical Center District Hotels by Brand

-   [Best Western Hotels](https://expedia.ca/Medical-Center-District-San-Antonio-Hotels-Best-Western.0-n553248635978913844-0--bBestWestern.Travel-Guide-Filter-Hotels)
-   [Drury Inn & Suites Hotels](https://expedia.ca/Medical-Center-District-San-Antonio-Hotels-Drury-Inn-Suites.0-n553248635978913844-0--bDruryInnSuites.Travel-Guide-Filter-Hotels)
-   [Hilton Hotels Hotels](https://expedia.ca/Medical-Center-District-San-Antonio-Hotels-Hilton-Hotels.0-n553248635978913844-0--bHiltonHotels.Travel-Guide-Filter-Hotels)
-   [Independent Hotels](https://expedia.ca/Medical-Center-District-San-Antonio-Hotels-Independent.0-n553248635978913844-0--bIndependent.Travel-Guide-Filter-Hotels)
-   [La Quinta Inn & Suites Hotels](https://expedia.ca/Medical-Center-District-San-Antonio-Hotels-La-Quinta-Inn-Suites.0-n553248635978913844-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)
-   [Marriott Hotels & Resorts Hotels](https://expedia.ca/Medical-Center-District-San-Antonio-Hotels-Marriott-Hotels-Resorts.0-n553248635978913844-0--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels)
-   [Motel 6 Hotels](https://expedia.ca/Medical-Center-District-San-Antonio-Hotels-Motel-6.0-n553248635978913844-0--bMotel6.Travel-Guide-Filter-Hotels)
-   [Omni Hotels](https://expedia.ca/Medical-Center-District-San-Antonio-Hotels-Omni.0-n553248635978913844-0--bOmni.Travel-Guide-Filter-Hotels)
-   [Red Lion Hotels](https://expedia.ca/Medical-Center-District-San-Antonio-Hotels-Red-Lion.0-n553248635978913844-0--bRedLion.Travel-Guide-Filter-Hotels)
-   [Red Roof Inn Hotels](https://expedia.ca/Medical-Center-District-San-Antonio-Hotels-Red-Roof-Inn.0-n553248635978913844-0--bRedRoofInn.Travel-Guide-Filter-Hotels)
-   [Wyndham Extra Holidays Hotels](https://expedia.ca/Medical-Center-District-San-Antonio-Hotels-Wyndham-Extra-Holidays.0-n553248635978913844-0--bWyndhamExtraHolidays.Travel-Guide-Filter-Hotels)

### Explore more hotels

-   [Hotel Contessa](https://expedia.ca/San-Antonio-Hotels-Hotel-Contessa-Suites-On-The-Riverwalk.h1234369.Hotel-Information)
-   [Crockett Hotel](https://expedia.ca/San-Antonio-Hotels-Crockett-Hotel.h1534.Hotel-Information)
-   [Menger Hotel](https://expedia.ca/San-Antonio-Hotels-Menger-Hotel.h5877.Hotel-Information)
-   [Hyatt Regency San Antonio Riverwalk](https://expedia.ca/San-Antonio-Hotels-Hyatt-Regency-San-Antonio-Riverwalk.h10636.Hotel-Information)
-   [The Westin Riverwalk, San Antonio](https://expedia.ca/San-Antonio-Hotels-The-Westin-Riverwalk.h330528.Hotel-Information)
-   [The Westin San Antonio North](https://expedia.ca/San-Antonio-Hotels-Omni-San-Antonio-Hotel-At-The-Colonnade.h3187.Hotel-Information)
-   [Omni La Mansion del Rio](https://expedia.ca/San-Antonio-Hotels-Omni-La-Mansion-Del-Rio.h17329.Hotel-Information)
-   [The St. Anthony, A Luxury Collection Hotel, San Antonio](https://expedia.ca/San-Antonio-Hotels-The-St-Anthony.h8789.Hotel-Information)
-   [La Quinta Inn & Suites by Wyndham San Antonio Downtown](https://expedia.ca/San-Antonio-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Antonio-Downtown.h421726.Hotel-Information)
-   [Red Roof Inn PLUS+ San Antonio Downtown - Riverwalk](https://expedia.ca/San-Antonio-Hotels-Red-Roof-Inn-PLUS-San-Antonio-Downtown-Riverwalk.h64197.Hotel-Information)
-   [Grand Hyatt San Antonio River Walk](https://expedia.ca/San-Antonio-Hotels-Grand-Hyatt-San-Antonio-River-Walk.h1848212.Hotel-Information)
-   [InterContinental San Antonio Riverwalk by IHG](https://expedia.ca/San-Antonio-Hotels-InterContinental-San-Antonio-Riverwalk.h50988.Hotel-Information)

[See a list of all hotels in San Antonio](https://expedia.ca/All-San-Antonio-Hotels.d178303.Travel-Guide-City-All-Hotels)

### More ways to book

-   [Book Hotels in Medical Center District on Expedia.com](https://www.expedia.com/Medical-Center-District-San-Antonio-Hotels.0-n553248635978913844-0.Travel-Guide-Filter-Hotels)

### Expedia's Latest Trends

Hotels

-   [Downtown Dallas hotels](https://expedia.ca/Downtown-Dallas-Dallas-Hotels.0-n800026-0.Travel-Guide-Filter-Hotels)
-   [Island Vista Resort](https://expedia.ca/Myrtle-Beach-Hotels-Island-Vista-Resort.h9779164.Hotel-Information)
-   [Red Lion Hotel Orlando Lake Buena Vista South](https://expedia.ca/Orlando-Hotels-Red-Lion-Hotel-Orlando-Lake-Buena-Vista-South.h7622.Hotel-Information)
-   [Downtown Austin hotels](https://expedia.ca/Downtown-Austin-Austin-Hotels.0-n6059085-0.Travel-Guide-Filter-Hotels)
-   [Best Western Ville-Marie Montreal Hotel & Suites](https://expedia.ca/Montreal-Hotels-Best-Western-Ville-Marie-Montreal-Hotel-Suites.h563088.Hotel-Information)
-   [Iberostar Waves Punta Cana - All Inclusive](https://expedia.ca/Punta-Cana-Hotels-Iberostar-Punta-Cana-All-Inclusive.h487018.Hotel-Information)
-   [Beach House Fort Lauderdale, a Hilton Resort](https://expedia.ca/Fort-Lauderdale-Hotels-Hilton-Fort-Lauderdale-Beach-Resort.h28591.Hotel-Information)
-   [Cheap Hotels in Downtown Austin](https://expedia.ca/Downtown-Austin-Austin-Hotels-Cheap-Hotels.0-n6059085-0-tCheapHotels.Travel-Guide-Filter-Hotels)
-   [Sechelt Inn](https://expedia.ca/Sechelt-Hotels-Driftwood-Motor-Inn.h9482408.Hotel-Information)
-   [Downtown Houston hotels](https://expedia.ca/Downtown-Houston-Houston-Hotels.0-n800037-0.Travel-Guide-Filter-Hotels)
-   [Fort Worth Stockyards hotels](https://expedia.ca/Fort-Worth-Stockyards-Fort-Worth-Hotels.0-n6190845-0.Travel-Guide-Filter-Hotels)

Flights

-   [Flights from Vancouver to Edmonton](https://expedia.ca/lp/flights/yvr/yeg/vancouver-to-edmonton)
-   [Flights to Nashville](https://expedia.ca/Cheap-Flights-To-Nashville.d178291.Travel-Guide-Flights)
-   [Flights from Edmonton to Victoria](https://expedia.ca/lp/flights/yeg/yyj/edmonton-to-victoria)
-   [Flights from Toronto to Indianapolis](https://expedia.ca/lp/flights/yyz/ind/toronto-to-indianapolis)
-   [Flights to Halifax](https://expedia.ca/Cheap-Flights-To-Halifax.d602873.Travel-Guide-Flights)
-   [Flights to Portland](https://expedia.ca/Cheap-Flights-To-Portland.d178299.Travel-Guide-Flights)
-   [Flights from Moncton to Delhi](https://expedia.ca/lp/flights/yqm/del/moncton-to-delhi)
-   [Flights from Edmonton to Nice](https://expedia.ca/lp/flights/yeg/nce/edmonton-to-nice)
-   [Flights from Montreal to Manila](https://expedia.ca/lp/flights/yul/mnl/montreal-to-manila)
-   [Cristiano Ronaldo Airport Flights](https://expedia.ca/lp/airports/fnc/flights-from-cristiano-ronaldo-airport)

Packages

-   [Punta Cana Vacations](https://expedia.ca/Punta-Cana.d601906.Destination-Travel-Guides)

General

-   [Visit Downtown Dallas](https://expedia.ca/Dallas-Downtown-Dallas.dx800026)
-   [Visit Downtown Houston](https://expedia.ca/Houston-Downtown-Houston.dx800037)
-   [Visit Fort Worth Stockyards](https://expedia.ca/Fort-Worth-Fort-Worth-Stockyards.dx6190845)
-   [Visit Downtown San Antonio](https://expedia.ca/San-Antonio-Downtown-San-Antonio.dx800120)
-   [Visit Tiki Island](https://expedia.ca/Galveston-Tiki-Island.dx3000398918)
-   [Visit Crystal Beach](https://expedia.ca/Port-Bolivar-Crystal-Beach.dx94245)
-   [Visit Downtown Austin](https://expedia.ca/Austin-Downtown-Austin.dx6059085)
-   [Visit Deep Ellum](https://expedia.ca/Dallas-Deep-Ellum.dx6190847)