Title: Hotels by Best Western in Perryville | Expedia.ca [Perryville Travel Guide](https://expedia.ca/Perryville.dx6134448)[Hotels in Perryville](https://expedia.ca/Perryville-Hotels.d6134448.Travel-Guide-Hotels)[Vacation Rentals in Perryville](https://expedia.ca/Perryville-Vacation-Rentals.d6134448.Travel-Guide-VacationRentals)[Flights to Perryville](https://expedia.ca/Cheap-Flights-To-Perryville.d6134448.Travel-Guide-Flights)[Things to do in Perryville](https://expedia.ca/Things-To-Do-In-Perryville.d6134448.Travel-Guide-Activities)[Perryville Car Rentals](https://expedia.ca/Car-Rentals-In-Perryville.d6134448.Car-Rental-Guide)[Perryville Vacation Packages](https://expedia.ca/Perryville.d6134448.Destination-Travel-Guides) ![Arched train bridge](https://images.trvl-media.com/place/6134448/9dc94c46-c0ab-4d3f-b5fe-2d6ecd4d81c3.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6134448/9dc94c46-c0ab-4d3f-b5fe-2d6ecd4d81c3.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Mar 21 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=6134448&startDate=2026-03-21&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 22 - Mar 23](https://www.expedia.ca/Hotel-Search?regionId=6134448&startDate=2026-03-22&endDate=2026-03-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 27 - Mar 29](https://www.expedia.ca/Hotel-Search?regionId=6134448&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Apr 3 - Apr 5](https://www.expedia.ca/Hotel-Search?regionId=6134448&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FPerryville-Hotels-Best-Western.0-0-d6134448--bBestWestern.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FPerryville-Hotels-Best-Western.0-0-d6134448--bBestWestern.Travel-Guide-Filter-Hotels) ## Top Perryville Hotel Reviews ![Drury Inn & Suites Jackson MO](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 10/10 Excellent "Great food and pool. Clean and cozy. We will be back! " [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Holiday Inn Express & Suites Perryville by IHG](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/469821a6_y.jpg) ### Holiday Inn Express & Suites Perryville by IHG 8/10 Good "Staff were friendly, rooms were clean, pool was nice. Bathroom door didn’t lock. Pull out couch mattress was worn so thin there was no padding to it. Bedframe was broken- wobbled when you moved. Room door had a lot of light and while it locked it wasn’t secure with all that space " [](https://expedia.ca/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ![Microtel Inn & Suites by Wyndham Sainte Genevieve](https://images.trvl-media.com/lodging/1000000/430000/426000/425932/96e79bac_y.jpg) ### Microtel Inn & Suites by Wyndham Sainte Genevieve 10/10 Excellent "Thank you, Ste. Genevieve Microtel staff. We loved the stay. Comfortable beds with clean and spacious room. Good continental breakfast! " [](https://expedia.ca/Ste-Genevieve-Hotels-Microtel-Inn-Suites-By-Wyndham-Sainte-Genevieve.h425932.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf_y.jpg) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau 10/10 Excellent "Hotel staff were friendly and helpful. Store and restaurants were a short drive away." [](https://expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Days Inn by Wyndham Perryville](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/6caf4858_y.jpg) ### Days Inn by Wyndham Perryville 6/10 Okay "furniture worn off, ok breakfast, but right off freeway so easy access" [](https://expedia.ca/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) ![Super 8 by Wyndham Perryville](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/e270ba08_y.jpg) ### Super 8 by Wyndham Perryville 6/10 Okay "We booked here bc the pictures show a hot tub , there is no hot tub. It’s been bricked in. The pictures do not represent the property. There were people swimming and running in the halls that were not staying there. I walked out side and they were running to their car in their swimsuits and running back in with pajamas on and waiting for guests to open the side door with their keys so they could enter the property. It appears the staff didn’t care. They were eating outside by their car and going inside to use the pool and bathrooms. I asked the girl if she was staying there when she expected me to open the side door for her , she admitted no. I explained she needed to go in the main entrance and she went back to the vehicle. 5 minutes later she was playing in the hall again. " [](https://expedia.ca/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ![Baymont by Wyndham Chester IL](https://images.trvl-media.com/lodging/1000000/10000/1700/1699/19091438_y.jpg) ### Baymont by Wyndham Chester IL 10/10 Excellent "Welcoming to pets. Nice clean property. Comfy beds." [](https://expedia.ca/Chester-Hotels-Baymont-By-Wyndham-Chester-IL.h1699.Hotel-Information) ![Retreat Air - King Bed, Hot Tub & No cleaning fee](https://images.trvl-media.com/lodging/124000000/123750000/123743600/123743557/5b24ebbb_y.jpg) ### Retreat Air - King Bed, Hot Tub & No cleaning fee 10/10 Excellent "Clean, comfortable bed, very welcoming. Kimberly was an awesome host and provided a home away from home that my wife and I the were looking for. We will stay here again. " [](https://expedia.ca/Perryville-Hotels-Retreat-Air-King-Bed.h123743557.Hotel-Information) ![Holiday Inn Express & Suites Murphysboro - Carbondale by IHG](https://images.trvl-media.com/lodging/64000000/63310000/63308800/63308723/cb237759_y.jpg) ### Holiday Inn Express & Suites Murphysboro - Carbondale by IHG 10/10 Excellent "Staff are super nice, helpful, and friendly! Breakfast was always great, good selection to choose from. Its clean and quiet, a perfect home away from home couldn't be happer!" 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