Panacea Vacation Rentals

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Panacea vacation rentals

☼ Short Walk to Beach! Canal Front w/ Game Room @ Flip-Flop Hideaway

☼ Short Walk to Beach! Canal Front w/ Game Room @ Flip-Flop Hideaway
Alligator Point
10.0 out of 10, Exceptional, (36 reviews)
"We loved our stay! Dog friendly & close to the beach, beautiful home! "
United States
rideitlikeyoustolei1
☼ Short Walk to Beach! Canal Front w/ Game Room @ Flip-Flop Hideaway

Secluded Florida Beach Bungalow-best of both worlds-BEACH TIME & FISHING TIME!!

Secluded Florida Beach Bungalow-best of both worlds-BEACH TIME & FISHING TIME!!
Panacea
10.0 out of 10, Exceptional, (247 reviews)
"2nd time staying here and it was so beautiful we will definitely be back, everything was wonderful and the host was amazing."
United States
Carrie J.
The price is CA $222
CA $554 total
includes taxes & fees
May 4 - May 5
Secluded Florida Beach Bungalow-best of both worlds-BEACH TIME & FISHING TIME!!

Fisherman's Retreat Entire home in Panacea, Florida

Fisherman's Retreat Entire home in Panacea, Florida
Panacea
The price is CA $112
CA $404 total
includes taxes & fees
Apr 6 - Apr 7
Fisherman's Retreat Entire home in Panacea, Florida

romantic get away for 2 right on the Ochlockonee river

romantic get away for 2 right on the Ochlockonee river
Panacea
6.0 out of 10, (2 reviews)
"Wonderful accommodations-clean and comfortable. "
United States
Laurie K.
The price is CA $182
CA $440 total
includes taxes & fees
Apr 6 - Apr 7
romantic get away for 2 right on the Ochlockonee river

Cozy Panacea Retreat #3 (King)

Cozy Panacea Retreat #3 (King)
Panacea
9.0 out of 10, Wonderful, (2 reviews)
"Great communication. Comfortable"
United States
Faith V.
The price is CA $197
CA $247 total
includes taxes & fees
Apr 8 - Apr 9
Cozy Panacea Retreat #3 (King)

NEW - St. Teresa Beach Escape w/ Private Beach Acc

NEW - St. Teresa Beach Escape w/ Private Beach Acc
Lanark Village
NEW - St. Teresa Beach Escape w/ Private Beach Acc

Skipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock

Skipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock
Panacea
9.8 out of 10, Exceptional, (96 reviews)
"We really enjoyed our time at Skipper! It's location on the west end of Alligator Point is perfect for walking the beach for miles in either direction. With so many shells to search for and so many dolphins to watch, our time there was so relaxing that we can't wait to go back!"
United States
Karen R.
The price is CA $294
CA $671 total
includes taxes & fees
Apr 17 - Apr 18
Skipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock

Point & Paddle Waterfront Retreat @Alligator Point

Point & Paddle Waterfront Retreat @Alligator Point
Alligator Point
10.0 out of 10, Exceptional, (2 reviews)
"Not only is this house adorable and roomy, it is the perfect mix of secluded and convenient. I hosted my girls for a little weekend birthday celebration and we had the best time watching the sunset from the dock, then enjoying a bonfire with smores! We played games and laughed well in to the night before finally retiring to the super comfy beds. The next morning we took the short walk to the beach and enjoyed discovering all types of nature while walking through the beaches of bald point state...
United States
Holley C.
The price is CA $251
CA $661 total
includes taxes & fees
Apr 13 - Apr 14
Point & Paddle Waterfront Retreat @Alligator Point

Private Beach & Dock - Quiet Waterfront Retreat on Ochlockonee Bay

Private Beach & Dock - Quiet Waterfront Retreat on Ochlockonee Bay
Panacea
10.0 out of 10, Exceptional, (1 review)
"host and the peace and ouietness of the area great for relaxing with out all of the giltter and gallyer"
United States
william C.
The price is CA $281
CA $677 total
includes taxes & fees
Apr 22 - Apr 23
Private Beach & Dock - Quiet Waterfront Retreat on Ochlockonee Bay

Cozy Panacea Retreat #7 (King)

Cozy Panacea Retreat #7 (King)
Panacea
The price is CA $197
CA $247 total
includes taxes & fees
Apr 6 - Apr 7
Cozy Panacea Retreat #7 (King)

09) Queen Kitchenette by the Bay

09) Queen Kitchenette by the Bay
Panacea
The price is CA $197
CA $247 total
includes taxes & fees
Apr 6 - Apr 7
09) Queen Kitchenette by the Bay

Queen Kitchenette by the Bay #15

Queen Kitchenette by the Bay #15
Panacea
The price is CA $197
CA $247 total
includes taxes & fees
Apr 7 - Apr 8
Queen Kitchenette by the Bay #15

Queen Kitchenette by the Bay #12

Queen Kitchenette by the Bay #12
Panacea
The price is CA $197
CA $247 total
includes taxes & fees
Apr 6 - Apr 7
Queen Kitchenette by the Bay #12

Queen Kitchenette by the Bay #11

Queen Kitchenette by the Bay #11
Panacea
The price is CA $197
CA $247 total
includes taxes & fees
Apr 6 - Apr 7
Queen Kitchenette by the Bay #11

Cozy Panacea Retreat #3 (King)

Cozy Panacea Retreat #3 (King)
Panacea
The price is CA $197
CA $247 total
includes taxes & fees
Apr 6 - Apr 7
Cozy Panacea Retreat #3 (King)

Queen Kitchenette by the Bay #14

Queen Kitchenette by the Bay #14
Panacea
The price is CA $197
CA $247 total
includes taxes & fees
Apr 6 - Apr 7
Queen Kitchenette by the Bay #14

Queen Kitchenette by the Bay #16

Queen Kitchenette by the Bay #16
Panacea
The price is CA $197
CA $247 total
includes taxes & fees
Apr 6 - Apr 7
Queen Kitchenette by the Bay #16

Queen Kitchenette by the Bay #10

Queen Kitchenette by the Bay #10
Panacea
The price is CA $197
CA $247 total
includes taxes & fees
Apr 6 - Apr 7
Queen Kitchenette by the Bay #10

Queen Kitchenette by the Bay #13

Queen Kitchenette by the Bay #13
Panacea
The price is CA $197
CA $247 total
includes taxes & fees
Apr 6 - Apr 7
Queen Kitchenette by the Bay #13

Queen Kitchenette by the Bay #17

Queen Kitchenette by the Bay #17
Panacea
The price is CA $214
CA $268 total
includes taxes & fees
Apr 6 - Apr 7
Queen Kitchenette by the Bay #17
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Panacea Hotel Reviews

Find out more about Panacea

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Panacea. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find vacation rentals in Panacea?

Yes, there are vacation rentals in Panacea close to Gulf Specimen Public Aquarum, or you can go with a secluded option if you'd like a relaxing place to stay. Visitors to Panacea speak positively about the beaches and seafood restaurants in this destination.

What are some of the best vacation rentals in Panacea?

Beautiful Waterfront, Pool, Private Hot Tub, Golf Cart, Kayaks, Bikes & Tennis: Visitors give good reviews to this Panacea vacation home rental, which is located by the ocean and has an outdoor pool, a balcony, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a selection of games and a hot tub. Some other homes for rent in Panacea include 5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch and Tiki House is a Unique Beach Front gathering spot for family, friends and PUPs..

How many vacation rentals are there in Panacea?

Choose from 172 Expedia vacation rentals in Panacea for a memorable vacation.

What’s there to see and do in Panacea?

Mashes Sand Beach and Wilson Beach are a couple of lovely local spots to enjoy the outdoors, whereas family-friendly attractions include Gulf Specimen Public Aquarum. While here, Alligator Point Beach and Bald Point State Park are other places worth a visit.

What’s a vacation rental in Panacea like?

Vacation rentals are privately owned properties where you can stay for a few weeks or just a few days in Panacea. Vacation rentals offer amenities like laundry facilities and kitchens so you'll have everything you need. If you're concerned about cleanliness, vacation rentals can offer a sense of seclusion away from shared hotel elevators and busy reception areas while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a hotel, which makes a vacation rental a popular choice for family trips or small group gatherings.