Title: Book the Best Tisbury SPA Resorts from CA $290 - Spa Hotels in Tisbury, MA | Expedia.ca [Hotels in Tisbury](https://expedia.ca/Tisbury-Hotels.d553248634998753684.Travel-Guide-Hotels)[Vacation Rentals in Tisbury](https://expedia.ca/Tisbury-Vacation-Rentals.d553248634998753684.Travel-Guide-VacationRentals)[Tisbury Car Rentals](https://expedia.ca/Car-Rentals-In-Tisbury.d553248634998753684.Car-Rental-Guide)[Tisbury Vacation Packages](https://expedia.ca/Tisbury.d553248634998753684.Destination-Travel-Guides) ![Ferries pass back and forth throughout the day, but their lights dance along the water at night when no one is looking. #adventure](https://images.trvl-media.com/place/553248634998753684/9092cf59-05f1-427b-aa78-4964d3cb4387.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Jon Burke ![](https://images.trvl-media.com/place/553248634998753684/9092cf59-05f1-427b-aa78-4964d3cb4387.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Tisbury Spa Hotels Tonight [Jan 16 - Jan 17](https://www.expedia.ca/Hotel-Search?regionId=553248634998753684&startDate=2026-01-16&endDate=2026-01-17&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 17 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=553248634998753684&startDate=2026-01-17&endDate=2026-01-18&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=553248634998753684&startDate=2026-01-16&endDate=2026-01-18&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=553248634998753684&startDate=2026-01-23&endDate=2026-01-25&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Tisbury hotels with a spa ![Beach nearby](https://images.trvl-media.com/lodging/3000000/2190000/2182100/2182094/04588712.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, 1 King Bed with Sofa bed](https://images.trvl-media.com/lodging/3000000/2190000/2182100/2182094/0cb6b6d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/3000000/2190000/2182100/2182094/2385000d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2190000/2182100/2182094/b950a23c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mansion House Inn And Spa [](https://www.expedia.ca/Vineyard-Haven-Hotels-Mansion-House-Inn-And-Spa.h2182094.Hotel-Information) Vineyard Haven 9.4/10 Exceptional (1,001 reviews) "Our second time staying. Friendly staff, perfect location, great views. Highly recommend." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kurt CA $241 CA $290 total includes taxes & fees Jan 21 - Jan 22 [](https://www.expedia.ca/Vineyard-Haven-Hotels-Mansion-House-Inn-And-Spa.h2182094.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/12900/12897/30f6a06a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/12900/12897/e05c3d69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12900/12897/b82acf26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/12900/12897/0ad12b76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Margaritaville Resort Cape Cod [](https://www.expedia.ca/Hyannis-Hotels-Cape-Codder-Resort-And-Spa.h12897.Hotel-Information) Hyannis 8.8/10 Excellent (428 reviews) "We are very happy with all the people at margaritaville, they are awesome 💝" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ewerton CA $374 CA $507 total includes taxes & fees Feb 13 - Feb 14 [](https://www.expedia.ca/Hyannis-Hotels-Cape-Codder-Resort-And-Spa.h12897.Hotel-Information) ![Suite | Bathroom](https://images.trvl-media.com/lodging/7000000/6670000/6664600/6664561/20cb5ae9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6670000/6664600/6664561/35461e89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served](https://images.trvl-media.com/lodging/7000000/6670000/6664600/6664561/942cd0d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/7000000/6670000/6664600/6664561/58199395.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Dan'l Webster Inn and Spa [](https://www.expedia.ca/Sandwich-Hotels-The-Danl-Webster-Inn-And-Spa.h6664561.Hotel-Information) Sandwich 9.0/10 Wonderful (542 reviews) "Location, friendly staff, cleanliness, ease of check in and out, atmosphere." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Barbara CA $255 CA $292 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Sandwich-Hotels-The-Danl-Webster-Inn-And-Spa.h6664561.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-30&endDate=2026-01-31®ionId=553248634998753684&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Tisbury Hotel Reviews ![Mansion House Inn And Spa](https://images.trvl-media.com/lodging/3000000/2190000/2182100/2182094/e86ce24b_y.jpg) ### Mansion House Inn And Spa 10/10 Excellent "My favorite place to stay on the Island! " [](https://expedia.ca/Vineyard-Haven-Hotels-Mansion-House-Inn-And-Spa.h2182094.Hotel-Information) ![Margaritaville Resort Cape Cod](https://images.trvl-media.com/lodging/1000000/20000/12900/12897/b57e0b1f_y.jpg) ### Margaritaville Resort Cape Cod 10/10 Excellent "Evrything is so clean! We love staying here with our family with small children. The kids love it and so do we! We go back every year. It's become a tradition! " [](https://expedia.ca/Hyannis-Hotels-Cape-Codder-Resort-And-Spa.h12897.Hotel-Information) ![Comfort Inn Hyannis - Cape Cod](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/f7a87ca8_y.jpg) ### Comfort Inn Hyannis - Cape Cod 10/10 Excellent "Very clean, and very helpful and friendly staff" [](https://expedia.ca/Hyannis-Hotels-Comfort-Inn.h1240460.Hotel-Information) ![Hyannis Plaza Hotel](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/f7fc1d07_y.jpg) ### Hyannis Plaza Hotel 10/10 Excellent "The best staff abd it was clean and beautiful " [](https://expedia.ca/Hyannis-Hotels-Hyannis-Plaza-Hotel.h1119277.Hotel-Information) ![Hyannis Travel Inn](https://images.trvl-media.com/lodging/2000000/1380000/1379200/1379109/fe11d49f_y.jpg) ### Hyannis Travel Inn 10/10 Excellent "Very kind staff. Functional, clean room. Had an early bus and they let me take a few things for breakfast the night before." [](https://expedia.ca/Hyannis-Hotels-Hyannis-Travel-Inn.h1379109.Hotel-Information) ## Frequently asked questions ### Looking for a spa hotel in Tisbury? ### What is the best spa hotel in Tisbury? ### How many spa hotels will I find in Tisbury? ### What's there to see and do in Tisbury? ### What is a Tisbury spa hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [Adults Only Resorts & in Boston ](https://www.expedia.ca/Boston-Hotels-Adults-Only-Resorts.0-0-d178239-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Business Hotels in Boston ](https://www.expedia.ca/Boston-Hotels-Business-Hotel.0-0-d178239-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in Boston ](https://www.expedia.ca/Boston-Hotels-Couples-Resorts-Hotels.0-0-d178239-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Golf Hotels in Boston ](https://www.expedia.ca/Boston-Hotels-Golf-Hotel.0-0-d178239-tGolfHotel.Travel-Guide-Filter-Hotels) - 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