Title: The 10 Best Hotels Near St. Louis Children's Hospital, St. Louis from CA $121 | Expedia.ca [Central West End Travel Guide](https://expedia.ca/St-Louis-Central-West-End.dx6175135)[St. Louis Children's Hospital Car Rentals](https://expedia.ca/Car-Rentals-In-St-Louis-Childrens-Hospital.d553248635389802716.Car-Rental-Guide)[St. Louis Children's Hospital Vacations](https://expedia.ca/St-Louis-Childrens-Hospital-Central-West-End.d553248635389802716.Vacation-Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels near St. Louis Children's Hospital, St. Louis from CA $121 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 18 - Dec 19](https://www.expedia.ca/Hotel-Search?regionId=553248635389802716&startDate=2025-12-18&endDate=2025-12-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 19 - Dec 20](https://www.expedia.ca/Hotel-Search?regionId=553248635389802716&startDate=2025-12-19&endDate=2025-12-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=553248635389802716&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248635389802716&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for St. Louis Children's Hospital hotels ![Exterior](https://images.trvl-media.com/lodging/2000000/1430000/1427900/1427801/8b38b72c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1430000/1427900/1427801/54db7486.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1430000/1427900/1427801/cca43ba9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1430000/1427900/1427801/3a42e755.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites St. Louis at Forest Park [](https://www.expedia.ca/St-Louis-Hotels-Hampton-Inn-Suites-St-Louis-At-Forest-Park.h1427801.Hotel-Information) Dogtown, 1.7 km from St. Louis Children's Hospital 9.4/10 Exceptional (1001) "The staff was so friendly and made our stay enjoyable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tracy CA $157 CA $185 total includes taxes & fees Jan 3 - Jan 4, 2026 [](https://www.expedia.ca/St-Louis-Hotels-Hampton-Inn-Suites-St-Louis-At-Forest-Park.h1427801.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1720000/1717400/1717380/6d4358f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/2000000/1720000/1717400/1717380/f3f5bbd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/2000000/1720000/1717400/1717380/7046b02d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1720000/1717400/1717380/b7d04b66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites St. Louis Forest Park [](https://www.expedia.ca/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Forest-Park.h1717380.Hotel-Information) 3 km from St. Louis Children's Hospital 9.4/10 Exceptional (1000) "Very clean room and great breakfast/dinner and snacks options. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Megan CA $158 CA $185 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Forest-Park.h1717380.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/72000000/71090000/71082600/71082568/eba0e02e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/72000000/71090000/71082600/71082568/4b03f0f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/72000000/71090000/71082600/71082568/b852011b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/72000000/71090000/71082600/71082568/b9448ebe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AC Hotel St. Louis Central West End [](https://www.expedia.ca/St-Louis-Hotels-AC-Hotel-St-Louis-Central-West-End.h71082568.Hotel-Information) Central West End, 0.8 km from St. Louis Children's Hospital 9.0/10 Wonderful (683) "Clean room, Helpful staff, Easy/cheap parking " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Delaney CA $175 CA $206 total includes taxes & fees Dec 27 - Dec 28 [](https://www.expedia.ca/St-Louis-Hotels-AC-Hotel-St-Louis-Central-West-End.h71082568.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/470000/465800/465749/9bee4fd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/470000/465800/465749/b33f7b0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/470000/465800/465749/8fec479e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/470000/465800/465749/af72bf51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Royal Sonesta Chase Park Plaza St. Louis [](https://www.expedia.ca/St-Louis-Hotels-The-Chase-Park-Plaza-Royal-Sonesta-St-Louis.h465749.Hotel-Information) Central West End, 0.7 km from St. Louis Children's Hospital 9.0/10 Wonderful (1002) "Always, a great time and place to stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lubna CA $208 CA $286 total includes taxes & fees Jan 18 - Jan 19, 2026 [](https://www.expedia.ca/St-Louis-Hotels-The-Chase-Park-Plaza-Royal-Sonesta-St-Louis.h465749.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/46000000/45770000/45765200/45765177/03e2f810.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exclusive Room, 1 King Bed, Garden View](https://images.trvl-media.com/lodging/46000000/45770000/45765200/45765177/109434dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exclusive Room, 1 King Bed, Connecting Rooms](https://images.trvl-media.com/lodging/46000000/45770000/45765200/45765177/64f2a4ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exclusive Room, 1 King Bed, Connecting Rooms](https://images.trvl-media.com/lodging/46000000/45770000/45765200/45765177/403b938e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Center Inn [](https://www.expedia.ca/St-Louis-Hotels-GRAND-CENTER-INN.h45765177.Hotel-Information) 2.8 km from St. Louis Children's Hospital 9.4/10 Exceptional (70) "Great! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) mike CA $229 CA $271 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/St-Louis-Hotels-GRAND-CENTER-INN.h45765177.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/58000000/57060000/57057200/57057177/3e830499.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/58000000/57060000/57057200/57057177/cf492d3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, pillowtop beds, individually furnished, desk](https://images.trvl-media.com/lodging/58000000/57060000/57057200/57057177/6a7bc7ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop bar](https://images.trvl-media.com/lodging/58000000/57060000/57057200/57057177/2abdcb73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Element St. Louis Midtown [](https://www.expedia.ca/St-Louis-Hotels-Element-St-Louis-Midtown.h57057177.Hotel-Information) Midtown, 2.2 km from St. Louis Children's Hospital 9.0/10 Wonderful (644) "Everything was excellent. The staff were very friendly and helpful. The accommodations were excellent and it was a great location near every where we were going." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela CA $181 CA $211 total includes taxes & fees Dec 26 - Dec 27 [](https://www.expedia.ca/St-Louis-Hotels-Element-St-Louis-Midtown.h57057177.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/50000000/49300000/49290300/49290300/289db51c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/50000000/49300000/49290300/49290300/19fa8377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/50000000/49300000/49290300/49290300/3701ee1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/50000000/49300000/49290300/49290300/3b0cb161.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aloft St. Louis Cortex [](https://www.expedia.ca/St-Louis-Hotels-Aloft-St-Louis-Cortex.h49290300.Hotel-Information) Central West End, 1.2 km from St. Louis Children's Hospital 8.6/10 Excellent (829) "Great Stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brandon Russell CA $151 CA $176 total includes taxes & fees Dec 27 - Dec 28 [](https://www.expedia.ca/St-Louis-Hotels-Aloft-St-Louis-Cortex.h49290300.Hotel-Information) ![Dining room](https://images.trvl-media.com/lodging/11000000/10510000/10503100/10503041/baa7d442.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/11000000/10510000/10503100/10503041/ef955718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, dishwasher, cookware/dishes/utensils](https://images.trvl-media.com/lodging/11000000/10510000/10503100/10503041/83450a4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/11000000/10510000/10503100/10503041/601d2d0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton St. Louis/Forest Park [](https://www.expedia.ca/St-Louis-Hotels-Home2-Suites-By-Hilton-St-LouisForest-Park.h10503041.Hotel-Information) The Grove, 0.8 km from St. Louis Children's Hospital 8.6/10 Excellent (1001) "Nice hotel. Very nice breakfast" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amir CA $157 CA $183 total includes taxes & fees Jan 18 - Jan 19, 2026 [](https://www.expedia.ca/St-Louis-Hotels-Home2-Suites-By-Hilton-St-LouisForest-Park.h10503041.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/107000000/106720000/106715700/106715696/ccf67b25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee/tea maker, highchair](https://images.trvl-media.com/lodging/107000000/106720000/106715700/106715696/49927158.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/107000000/106720000/106715700/106715696/2c313b99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family dining](https://images.trvl-media.com/lodging/107000000/106720000/106715700/106715696/0cdb491f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The West End [](https://www.expedia.ca/St-Louis-Hotels-The-West-End.h106715696.Hotel-Information) Central West End, 1.4 km from St. Louis Children's Hospital 8.6/10 Excellent (408) "Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shaniqua CA $96 CA $138 total includes taxes & fees Jan 6 - Jan 7, 2026 [](https://www.expedia.ca/St-Louis-Hotels-The-West-End.h106715696.Hotel-Information) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1090000/1082400/1082373/3f93ad2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1090000/1082400/1082373/fb148803.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed](https://images.trvl-media.com/lodging/2000000/1090000/1082400/1082373/15edbb89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1090000/1082400/1082373/ce4899f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton St. Louis Forest Park [](https://www.expedia.ca/St-Louis-Hotels-DoubleTree-By-Hilton-St-Louis-Forest-Park.h1082373.Hotel-Information) Central West End, 0.3 km from St. Louis Children's Hospital 8.2/10 Very good (1001) "The guy at check in was super nice. What I love the most is they give you freshly baked scrumptious oatmeal chocolate chip cookies (that melt in your mouth) throughout your stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gloria CA $150 CA $177 total includes taxes & fees Jan 12 - Jan 13, 2026 [](https://www.expedia.ca/St-Louis-Hotels-DoubleTree-By-Hilton-St-Louis-Forest-Park.h1082373.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/25bc97a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/fe6513ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/3653d011.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Suite, 2 Bedrooms | Private kitchen](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/0083e033.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Angad Arts Hotel St. Louis, Tapestry Collection by Hilton [](https://www.expedia.ca/St-Louis-Hotels-Angad-Arts-Hotel-St-Louis.h27616925.Hotel-Information) 3 km from St. Louis Children's Hospital 8.8/10 Excellent (1031) "Fun staff and a very cool hotel. Great room, too!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christopher CA $164 CA $193 total includes taxes & fees Dec 27 - Dec 28 [](https://www.expedia.ca/St-Louis-Hotels-Angad-Arts-Hotel-St-Louis.h27616925.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/22100/22068/bd89b9ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed | Room amenity](https://images.trvl-media.com/lodging/1000000/30000/22100/22068/61364f25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/30000/22100/22068/34577ba0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22100/22068/3285eddf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Indigo St Louis - Central West End by IHG [](https://www.expedia.ca/St-Louis-Hotels-Holiday-Inn-Express-St-Louis-Central-West-End.h22068.Hotel-Information) Central West End, 0.7 km from St. Louis Children's Hospital 8.2/10 Very good (1000) "Very friendly staff. Clean modern hotel room with comfortable bed and spacious shower! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Courtney CA $160 CA $204 total includes taxes & fees Jan 18 - Jan 19, 2026 [](https://www.expedia.ca/St-Louis-Hotels-Holiday-Inn-Express-St-Louis-Central-West-End.h22068.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/22300/22298/21d70af8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/22300/22298/623aa763.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels, soap](https://images.trvl-media.com/lodging/1000000/30000/22300/22298/fa7a7814.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room](https://images.trvl-media.com/lodging/1000000/30000/22300/22298/460db328.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Forest Park Hotel by MDR [](https://www.expedia.ca/St-Louis-Hotels-Holiday-Inn-St-Louis-Forest-Park.h22298.Hotel-Information) The Hill, 2.9 km from St. Louis Children's Hospital 7.6/10 Good (1274) "location attentive staff large king room" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephen [](https://www.expedia.ca/St-Louis-Hotels-Holiday-Inn-St-Louis-Forest-Park.h22298.Hotel-Information) ![ (Lil Dynasty) No Private Bathroom ](https://images.trvl-media.com/lodging/18000000/17680000/17678300/17678265/1d4cc219.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Private Bathroom (Reflections)](https://images.trvl-media.com/lodging/18000000/17680000/17678300/17678265/4bba56a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Private Bathroom (Diamonds and Pearls Luxury Suite)](https://images.trvl-media.com/lodging/18000000/17680000/17678300/17678265/bb0770c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Private Bathroom (Asia)](https://images.trvl-media.com/lodging/18000000/17680000/17678300/17678265/be8fe357.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Central West End B&B [](https://www.expedia.ca/St-Louis-Hotels-Central-West-End-Bed-And-Breakfast.h17678265.Hotel-Information) Central West End, 2.1 km from St. Louis Children's Hospital 7.8/10 Good (53) "Really enjoyed the comfort. I would recommend this place to anyone. Very nice breakfast also!!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stacee CA $215 CA $272 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/St-Louis-Hotels-Central-West-End-Bed-And-Breakfast.h17678265.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24500/24411/3904d866.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24500/24411/7a52099f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/24500/24411/c394d816.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, 2 Double Beds (Upgraded Bedding & Snack, Smoke Free)](https://images.trvl-media.com/lodging/1000000/30000/24500/24411/ec8ba901.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave [](https://www.expedia.ca/St-Louis-Hotels-Red-Roof-Inn-PLUS-St-Louis-Forest-Park-Hampton-Ave.h24411.Hotel-Information) The Hill, 2.8 km from St. Louis Children's Hospital 5.8/10 (1001) "Needs remodeling and new furniture " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) antwon CA $103 CA $121 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/St-Louis-Hotels-Red-Roof-Inn-PLUS-St-Louis-Forest-Park-Hampton-Ave.h24411.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/fe8445aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/w2897h2195x0y8-cdf51e05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/db6ee37f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, City View](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/ff34bd9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Moonrise Hotel [](https://www.expedia.ca/St-Louis-Hotels-Moonrise-Hotel.h2292856.Hotel-Information) 3.6 km from St. Louis Children's Hospital 9.0/10 Wonderful (1914) "Clean rooms, good coffee and fresh muffins and friendly service." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Colleen CA $163 CA $193 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/St-Louis-Hotels-Moonrise-Hotel.h2292856.Hotel-Information) ![Pub](https://images.trvl-media.com/lodging/39000000/38720000/38711900/38711810/302445f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/39000000/38720000/38711900/38711810/a9bf89ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/39000000/38720000/38711900/38711810/35cc392e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/39000000/38720000/38711900/38711810/cc76404d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Knight Center at Washington University [](https://www.expedia.ca/St-Louis-Hotels-The-Charles-F-Knight-Center.h38711810.Hotel-Information) 4.3 km from St. Louis Children's Hospital 9.4/10 Exceptional (446) "The hotel is beautiful and the staff is very helpful and kind. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Beth CA $171 CA $197 total includes taxes & fees Jan 2 - Jan 3, 2026 [](https://www.expedia.ca/St-Louis-Hotels-The-Charles-F-Knight-Center.h38711810.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/40000/37700/37651/151222b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/40000/37700/37651/fde81462.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/40000/37700/37651/0467986d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/40000/37700/37651/1dea3ddf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites St. Louis Union Station [](https://www.expedia.ca/St-Louis-Hotels-Drury-Inn-St-Louis-At-Union-Station.h37651.Hotel-Information) Downtown West, 4.9 km from St. Louis Children's Hospital 9.4/10 Exceptional (1302) "Nice hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vivian CA $164 CA $195 total includes taxes & fees Jan 13 - Jan 14, 2026 [](https://www.expedia.ca/St-Louis-Hotels-Drury-Inn-St-Louis-At-Union-Station.h37651.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/37000000/36350000/36342700/36342606/d5bd0f6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/37000000/36350000/36342700/36342606/ad6cb127.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/37000000/36350000/36342700/36342606/d7bff3ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/37000000/36350000/36342700/36342606/e7617ff9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott St. Louis Brentwood [](https://www.expedia.ca/St-Louis-Hotels-Courtyard-By-Marriott-St-Louis-Brentwood.h36342606.Hotel-Information) 6 km from St. Louis Children's Hospital 9.4/10 Exceptional (837) "We always enjoy our stay here nice clean and great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dominique CA $139 CA $171 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/St-Louis-Hotels-Courtyard-By-Marriott-St-Louis-Brentwood.h36342606.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/45000000/44010000/44005400/44005380/fd79d4c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/45000000/44010000/44005400/44005380/f0d9e7fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/45000000/44010000/44005400/44005380/9e2897b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/45000000/44010000/44005400/44005380/f4a32958.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott St. Louis Downtown [](https://www.expedia.ca/St-Louis-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Louis-Downtown.h44005380.Hotel-Information) Downtown West, 4.7 km from St. Louis Children's Hospital 9.2/10 Wonderful (1002) "Breakfast menu was fresh and tasty. Will return in the future with more time to go to the national park!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Silvar CA $147 CA $176 total includes taxes & fees Dec 25 - Dec 26 [](https://www.expedia.ca/St-Louis-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Louis-Downtown.h44005380.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-01&endDate=2026-01-02®ionId=553248635389802716&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top St. Louis Children's Hospital Hotel Reviews ![Home2 Suites by Hilton St. Louis/Forest Park](https://images.trvl-media.com/lodging/11000000/10510000/10503100/10503041/baa7d442_y.jpg) ### Home2 Suites by Hilton St. Louis/Forest Park 10/10 Excellent "Would have liked an egg option. The hotel and service were great however they didn’t have my reservation. Upon check in they didn’t have me in the system. They eventually found me in the Expedia app but still couldn’t access the reservation. The hotel just gave me a room and said they would handle with Hotels.com after which I appreciated. Really bummed us out having to wait to figure out why it wasn’t in the system. Do better Hotels.com." [](https://expedia.ca/St-Louis-Hotels-Home2-Suites-By-Hilton-St-LouisForest-Park.h10503041.Hotel-Information) ![Element St. Louis Midtown](https://images.trvl-media.com/lodging/58000000/57060000/57057200/57057177/3e830499_y.jpg) ### Element St. Louis Midtown 10/10 Excellent "The room was spacious, and the staff were as friendly and helpful as any I have ever met. " [](https://expedia.ca/St-Louis-Hotels-Element-St-Louis-Midtown.h57057177.Hotel-Information) ![The West End](https://images.trvl-media.com/lodging/107000000/106720000/106715700/106715696/ccf67b25_y.jpg) ### The West End 10/10 Excellent "The staff was courteous. Good location, and liked the parking garage." [](https://expedia.ca/St-Louis-Hotels-The-West-End.h106715696.Hotel-Information) ![Hampton Inn & Suites St. Louis at Forest Park](https://images.trvl-media.com/lodging/2000000/1430000/1427900/1427801/8b38b72c_y.jpg) ### Hampton Inn & Suites St. Louis at Forest Park 10/10 Excellent "Clean room, friendly staff " [](https://expedia.ca/St-Louis-Hotels-Hampton-Inn-Suites-St-Louis-At-Forest-Park.h1427801.Hotel-Information) ![Aloft St. Louis Cortex](https://images.trvl-media.com/lodging/50000000/49300000/49290300/49290300/289db51c_y.jpg) ### Aloft St. Louis Cortex 10/10 Excellent "Great Stay " [](https://expedia.ca/St-Louis-Hotels-Aloft-St-Louis-Cortex.h49290300.Hotel-Information) ![Angad Arts Hotel St. Louis, Tapestry Collection by Hilton](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/25bc97a8_y.jpg) ### Angad Arts Hotel St. Louis, Tapestry Collection by Hilton 10/10 Excellent "We always stay here when seeing a show at the Fox Theatre. Love it!!" [](https://expedia.ca/St-Louis-Hotels-Angad-Arts-Hotel-St-Louis.h27616925.Hotel-Information) ![AC Hotel St. Louis Central West End](https://images.trvl-media.com/lodging/72000000/71090000/71082600/71082568/eba0e02e_y.jpg) ### AC Hotel St. Louis Central West End 10/10 Excellent "The room was clean and appeared to have been recently updated. The staff were especially courteous and accommodating during my stay. " [](https://expedia.ca/St-Louis-Hotels-AC-Hotel-St-Louis-Central-West-End.h71082568.Hotel-Information) ![ The Royal Sonesta Chase Park Plaza St. Louis](https://images.trvl-media.com/lodging/1000000/470000/465800/465749/9bee4fd7_y.jpg) ### The Royal Sonesta Chase Park Plaza St. Louis 10/10 Excellent "Everything was excellent. " [](https://expedia.ca/St-Louis-Hotels-The-Chase-Park-Plaza-Royal-Sonesta-St-Louis.h465749.Hotel-Information) ![Forest Park Hotel by MDR](https://images.trvl-media.com/lodging/1000000/30000/22300/22298/21d70af8_y.jpg) ### Forest Park Hotel by MDR 10/10 Excellent "Great room staff nice " [](https://expedia.ca/St-Louis-Hotels-Holiday-Inn-St-Louis-Forest-Park.h22298.Hotel-Information) ## Hotels near other St. Louis Children's Hospital attractions ![St. Louis](https://images.trvl-media.com/place/553248621555612614/f5c81b46-6015-49d2-9ee5-a58e9186f716.jpg) ### World Chess Hall of Fame Play a game of chess on a giant outdoor board, inspect chess-related artifacts and view artworks inspired by the two-player board game at this fascinating center. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621555612614) ![Sanctuary in the Cathedral Basilica of Saint Louis on Lindell Boulevard in St. Louis, Missouri](https://images.trvl-media.com/place/6069379/a60a0089-7d47-4bd2-909e-b5d8200463c4.jpg) ### Cathedral Basilica of St. Louis After visiting Cathedral Basilica of St. Louis, make a plan to see the other sights and activities in St. Louis. Experience the area's great live music and acclaimed art scene. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6069379) ![You must visit this center it should be on your list why? Because family friendly place](https://images.trvl-media.com/place/3284/bec54e6a-1ec8-4ffc-9203-5492e745af5c.jpg) Photo by Nawa Aseen ### St. Louis Science Center 4.5/5 (387 reviews) You can spend time studying the exhibits at St. Louis Science Center during your travels in St. Louis. Experience the area's acclaimed art scene and great live music. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=502861) ![Grand Basin looking from top of Art Hill in Forest Park, St. Louis, Missouri](https://images.trvl-media.com/place/6005687/6a48afd8-f12d-4336-91f1-21e5f7dcf5c4.jpg) ### Forest Park 4.6/5 (2,094 reviews) Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6005687) ![Cabanne House](https://images.trvl-media.com/place/553248635892175015/13d907a2-8beb-4737-a54b-b19884e5d716.jpg) ### Cabanne House Attend a private wedding or musical rehearsal in the historic setting of the first brick farmhouse built west of the Mississippi River. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635892175015) ![Forest Park](https://images.trvl-media.com/place/553248635823456129/31a7e052-df36-4de6-ab04-772d1de8c62d.jpg) ### Jewel Box Made of stacked glass in a restored art deco style, this glass house from the 1930s continues to flourish with tropical trees, hanging plants and a large fountain. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635823456129) ![Pagoda Circle featuring heritage elements, a pond and bird life](https://images.trvl-media.com/place/553248635810227311/1a3c426c-0102-47a7-a244-05819335714b.jpg) ### Pagoda Circle As one of the cornerstones of Forest Park for about a century, this grassy island and its bandstand offer an excellent concert spot. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635810227311) ### Highlands Golf & Tennis Center Catch an event at Highlands Golf & Tennis Center during your trip to St. Louis. Experience the area's entertainment choices or attend a baseball game. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=941624749059428352) ## Frequently asked questions ### What's the area like around St. Louis Children's Hospital? ### What's the best hotel to stay near St. Louis Children's Hospital? ### How many hotels can I expect to find close to St. Louis Children's Hospital? ### If I need to cancel the hotel reservation for my stay near St. Louis Children's Hospital, will I receive a refund? ### What can I see and do near St. Louis Children's Hospital? ### How can I get to St. Louis Children's Hospital? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - [5 Star Hotels in Skinker DeBaliviere ](https://www.expedia.ca/5Star-Skinker-DeBaliviere-St-Louis-Hotels.s50-n887273043026735104-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in The Grove ](https://www.expedia.ca/5Star-The-Grove-St-Louis-Hotels.s50-n808797266555363328-0.Travel-Guide-Filter-Hotels) - [Academy - Sherman Park Hotels ](https://www.expedia.ca/Academy-Sherman-Park-St-Louis-Hotels.0-n553248635976472137-0.Travel-Guide-Filter-Hotels) - 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