Title: The 10 Best Hotels Near St. Louis Science Center, St. Louis from CA $131 | Expedia.ca [Kings Oak Travel Guide](https://expedia.ca/St-Louis-Kings-Oak.dx896161834730729472)[St. Louis Science Center Car Rentals](https://expedia.ca/Car-Rentals-In-St-Louis-Science-Center.d502861.Car-Rental-Guide)[St. Louis Science Center Vacations](https://expedia.ca/St-Louis-Science-Center-Kings-Oak.d502861.Vacation-Attraction) ![](https://images.trvl-media.com/place/502861/cc796f06-6269-49b0-b73e-a533ef69790e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/502861/cc796f06-6269-49b0-b73e-a533ef69790e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Apr 7 - Apr 8](https://www.expedia.ca/Hotel-Search?regionId=502861&startDate=2026-04-07&endDate=2026-04-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Apr 8 - Apr 9](https://www.expedia.ca/Hotel-Search?regionId=502861&startDate=2026-04-08&endDate=2026-04-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=502861&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 17 - Apr 19](https://www.expedia.ca/Hotel-Search?regionId=502861&startDate=2026-04-17&endDate=2026-04-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for St. Louis Science Center hotels ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1430000/1427900/1427801/cca43ba9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1430000/1427900/1427801/f90b5a19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1430000/1427900/1427801/8b38b72c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1430000/1427900/1427801/a48fd573.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites St. Louis at Forest Park [](https://www.expedia.ca/St-Louis-Hotels-Hampton-Inn-Suites-St-Louis-At-Forest-Park.h1427801.Hotel-Information) Dogtown, 1 km from St. Louis Science Center 9.2/10 Wonderful (1,007 reviews) "Great stay, great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle CA $181 CA $214 total includes taxes & fees Apr 19 - Apr 20 [](https://www.expedia.ca/St-Louis-Hotels-Hampton-Inn-Suites-St-Louis-At-Forest-Park.h1427801.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1720000/1717400/1717380/6d4358f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cribs/infant beds, rollaway beds](https://images.trvl-media.com/lodging/2000000/1720000/1717400/1717380/2e11bb15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1720000/1717400/1717380/b7d04b66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/2000000/1720000/1717400/1717380/b693e67c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites St. Louis Forest Park [](https://www.expedia.ca/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Forest-Park.h1717380.Hotel-Information) 2 km from St. Louis Science Center 9.4/10 Exceptional (1,009 reviews) "Nice, powerful hot tub, spacious and clean room, great & attentive staff, wonderful food & drinks." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janet CA $200 CA $234 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Forest-Park.h1717380.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/470000/465800/465749/9bee4fd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/470000/465800/465749/b33f7b0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/470000/465800/465749/e67e5404.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/470000/465800/465749/34e1f351.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Royal Sonesta Chase Park Plaza St. Louis [](https://www.expedia.ca/St-Louis-Hotels-The-Chase-Park-Plaza-Royal-Sonesta-St-Louis.h465749.Hotel-Information) Central West End, 1.8 km from St. Louis Science Center 9.0/10 Wonderful (1,009 reviews) "Beautiful hotel, room was extremely clean and The Preston Restaurant was ordered for room service and the food was awesome!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kamyra CA $292 CA $386 total includes taxes & fees Apr 19 - Apr 20 [](https://www.expedia.ca/St-Louis-Hotels-The-Chase-Park-Plaza-Royal-Sonesta-St-Louis.h465749.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/72000000/71090000/71082600/71082568/937991c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/72000000/71090000/71082600/71082568/cf784226.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/72000000/71090000/71082600/71082568/f524d74a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/72000000/71090000/71082600/71082568/4b03f0f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AC Hotel St. Louis Central West End [](https://www.expedia.ca/St-Louis-Hotels-AC-Hotel-St-Louis-Central-West-End.h71082568.Hotel-Information) Central West End, 1.8 km from St. Louis Science Center 9.0/10 Wonderful (731 reviews) "Many thanks to Renya and Queen at the front desk." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deniz CA $211 CA $249 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/St-Louis-Hotels-AC-Hotel-St-Louis-Central-West-End.h71082568.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/11000000/10510000/10503100/10503041/c6cc2b03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/11000000/10510000/10503100/10503041/6bafa9b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining room](https://images.trvl-media.com/lodging/11000000/10510000/10503100/10503041/baa7d442.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/11000000/10510000/10503100/10503041/9b2b4e53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton St. Louis/Forest Park [](https://www.expedia.ca/St-Louis-Hotels-Home2-Suites-By-Hilton-St-LouisForest-Park.h10503041.Hotel-Information) The Grove, 0.9 km from St. Louis Science Center 8.6/10 Excellent (1,011 reviews) "The front desk host, Erica was truly amazing. She made us feel welcome, was very knowledgeable and friendly. Having the shuttle take us to the hospital and back was so convenient. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Regan CA $199 CA $233 total includes taxes & fees Apr 19 - Apr 20 [](https://www.expedia.ca/St-Louis-Hotels-Home2-Suites-By-Hilton-St-LouisForest-Park.h10503041.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/58000000/57060000/57057200/57057177/3e830499.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/58000000/57060000/57057200/57057177/e2c45e75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop bar](https://images.trvl-media.com/lodging/58000000/57060000/57057200/57057177/8a51369f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/58000000/57060000/57057200/57057177/9745e8b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Element St. Louis Midtown [](https://www.expedia.ca/St-Louis-Hotels-Element-St-Louis-Midtown.h57057177.Hotel-Information) Midtown, 2.7 km from St. Louis Science Center 9.0/10 Wonderful (713 reviews) "We had a wonderful stay at Element Hotel. Very clean, quiet, convenient location. We felt safe here and the staff was very kind and helpful. The room our family of 5 stayed in was spacious and had a wonderful kitchenette. We would stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lauren CA $188 CA $220 total includes taxes & fees May 3 - May 4 [](https://www.expedia.ca/St-Louis-Hotels-Element-St-Louis-Midtown.h57057177.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/107000000/106720000/106715700/106715696/74ffd1da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/107000000/106720000/106715700/106715696/1f832e9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/107000000/106720000/106715700/106715696/f77b5588.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/107000000/106720000/106715700/106715696/3e1d4fbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The West End [](https://www.expedia.ca/St-Louis-Hotels-The-West-End.h106715696.Hotel-Information) Central West End, 2.3 km from St. Louis Science Center 8.6/10 Excellent (469 reviews) "Very welcoming staff, hotel was clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela CA $126 CA $175 total includes taxes & fees Apr 15 - Apr 16 [](https://www.expedia.ca/St-Louis-Hotels-The-West-End.h106715696.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/22100/22068/bd89b9ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22100/22068/664f8ef2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cafe](https://images.trvl-media.com/lodging/1000000/30000/22100/22068/2ea98741.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/30000/22100/22068/ab186cc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Indigo St Louis - Central West End by IHG [](https://www.expedia.ca/St-Louis-Hotels-Holiday-Inn-Express-St-Louis-Central-West-End.h22068.Hotel-Information) Central West End, 1.7 km from St. Louis Science Center 8.4/10 Very good (1,009 reviews) "Clean room and good staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gregory CA $195 CA $245 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/St-Louis-Hotels-Holiday-Inn-Express-St-Louis-Central-West-End.h22068.Hotel-Information) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1090000/1082400/1082373/ce4899f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (USD 14.50 per person)](https://images.trvl-media.com/lodging/2000000/1090000/1082400/1082373/8de3247b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1090000/1082400/1082373/b6c6745d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed](https://images.trvl-media.com/lodging/2000000/1090000/1082400/1082373/15edbb89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton St. Louis Forest Park [](https://www.expedia.ca/St-Louis-Hotels-DoubleTree-By-Hilton-St-Louis-Forest-Park.h1082373.Hotel-Information) Central West End, 1.3 km from St. Louis Science Center 8.2/10 Very good (1,004 reviews) "The room was clean and comfortable, the staff was friendly and accommodating. Perfect for our stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rebecca CA $181 CA $214 total includes taxes & fees Apr 19 - Apr 20 [](https://www.expedia.ca/St-Louis-Hotels-DoubleTree-By-Hilton-St-Louis-Forest-Park.h1082373.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/84000000/83130000/83121100/83121050/f3c125ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/84000000/83130000/83121100/83121050/0bbeb61f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment | Interior entrance](https://images.trvl-media.com/lodging/84000000/83130000/83121100/83121050/55f5dbb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | Living area](https://images.trvl-media.com/lodging/84000000/83130000/83121100/83121050/4a627d76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### White House at Grand Central [](https://www.expedia.ca/St-Louis-Hotels-Grand-Center-Apartments.h83121050.Hotel-Information) 3 km from St. Louis Science Center 8.4/10 Very good (130 reviews) "Great place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kerry CA $117 CA $186 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/St-Louis-Hotels-Grand-Center-Apartments.h83121050.Hotel-Information) ![Standard Double Room](https://images.trvl-media.com/lodging/1000000/30000/22300/22298/460db328.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/22300/22298/7ae052ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/22300/22298/623aa763.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels, soap](https://images.trvl-media.com/lodging/1000000/30000/22300/22298/fa7a7814.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Forest Park Hotel by MDR [](https://www.expedia.ca/St-Louis-Hotels-Holiday-Inn-St-Louis-Forest-Park.h22298.Hotel-Information) The Hill, 1.8 km from St. Louis Science Center 7.6/10 Good (1,452 reviews) "Clean room and friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer CA $112 CA $136 total includes taxes & fees Apr 8 - Apr 9 [](https://www.expedia.ca/St-Louis-Hotels-Holiday-Inn-St-Louis-Forest-Park.h22298.Hotel-Information) ![Suite, Private Bathroom (Diamonds and Pearls Luxury Suite)](https://images.trvl-media.com/lodging/18000000/17680000/17678300/17678265/4d85105d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Private Bathroom](https://images.trvl-media.com/lodging/18000000/17680000/17678300/17678265/46a6046b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Private Bathroom (Reflections)](https://images.trvl-media.com/lodging/18000000/17680000/17678300/17678265/4bba56a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Private Bathroom](https://images.trvl-media.com/lodging/18000000/17680000/17678300/17678265/133b0297.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Central West End B&B [](https://www.expedia.ca/St-Louis-Hotels-Central-West-End-Bed-And-Breakfast.h17678265.Hotel-Information) Central West End, 3 km from St. Louis Science Center 8.0/10 Very good (55 reviews) "My husband & I were very impressed with the hostess Ms. Henrietta Taylor she made us feel at home with her hospitality. She keeps the establishment immaculate, and served a scrumptious homemade breakfast! I highly recommend this bed & breakfast in the Central West End of St. Louis, Missouri to all family & friends! 2 Thumbs Up 👍👍!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tammy CA $222 CA $280 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/St-Louis-Hotels-Central-West-End-Bed-And-Breakfast.h17678265.Hotel-Information) ![Superior Room, 1 King Bed (Smoke Free)](https://images.trvl-media.com/lodging/1000000/30000/24500/24411/2cedd544.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/24500/24411/f15bf15e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/30000/24500/24411/4dcd9d29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24500/24411/3904d866.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave [](https://www.expedia.ca/St-Louis-Hotels-Red-Roof-Inn-PLUS-St-Louis-Forest-Park-Hampton-Ave.h24411.Hotel-Information) The Hill, 1.8 km from St. Louis Science Center 5.8/10 (1,001 reviews) "I feel the place is not safe. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ma Eloisa CA $112 CA $131 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/St-Louis-Hotels-Red-Roof-Inn-PLUS-St-Louis-Forest-Park-Hampton-Ave.h24411.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/46000000/45770000/45765200/45765177/03e2f810.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor wedding area](https://images.trvl-media.com/lodging/46000000/45770000/45765200/45765177/fd41b80b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/46000000/45770000/45765200/45765177/ae513ea3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/46000000/45770000/45765200/45765177/2d13aedc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Center Inn [](https://www.expedia.ca/St-Louis-Hotels-GRAND-CENTER-INN.h45765177.Hotel-Information) 3.5 km from St. Louis Science Center 9.4/10 Exceptional (82 reviews) "Absolutely beautiful facilities. Room was so comfortable and we loved having space! A comfortable couch, fireplace, desk, chairs....It was just great. Bed was very comfortable. Bathroom was HUGE! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cheryl CA $229 CA $270 total includes taxes & fees Apr 13 - Apr 14 [](https://www.expedia.ca/St-Louis-Hotels-GRAND-CENTER-INN.h45765177.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/39000000/38720000/38711900/38711810/a9bf89ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/39000000/38720000/38711900/38711810/90b4f887.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pub](https://images.trvl-media.com/lodging/39000000/38720000/38711900/38711810/302445f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/39000000/38720000/38711900/38711810/9c80d4ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Knight Center at Washington University [](https://www.expedia.ca/St-Louis-Hotels-The-Charles-F-Knight-Center.h38711810.Hotel-Information) 4.3 km from St. Louis Science Center 9.4/10 Exceptional (513 reviews) "Great place to stay on campus. Extremely helpful and friendly staff you don’t typically find at the chain hotels. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $223 CA $257 total includes taxes & fees May 4 - May 5 [](https://www.expedia.ca/St-Louis-Hotels-The-Charles-F-Knight-Center.h38711810.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/w2897h2195x0y8-cdf51e05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/150f8d2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, rooftop bar](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/996a216e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/10a24838.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Moonrise Hotel [](https://www.expedia.ca/St-Louis-Hotels-Moonrise-Hotel.h2292856.Hotel-Information) 3.8 km from St. Louis Science Center 9.0/10 Wonderful (1,922 reviews) "Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $193 CA $229 total includes taxes & fees Apr 19 - Apr 20 [](https://www.expedia.ca/St-Louis-Hotels-Moonrise-Hotel.h2292856.Hotel-Information) ![Hallway](https://images.trvl-media.com/lodging/18000000/17330000/17326600/17326573/c44211f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/18000000/17330000/17326600/17326573/790c3c44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/18000000/17330000/17326600/17326573/3006689e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/18000000/17330000/17326600/17326573/f26ee42c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Benton Park Inn [](https://www.expedia.ca/St-Louis-Hotels-Benton-Park-Inn.h17326573.Hotel-Information) 5.5 km from St. Louis Science Center 9.6/10 Exceptional (321 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Conor CA $193 CA $225 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/St-Louis-Hotels-Benton-Park-Inn.h17326573.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/40000/37700/37651/151222b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/40000/37700/37651/724b1fd8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/40000/37700/37651/7a6739c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed (Sofa Sleeper, 2 Rooms)](https://images.trvl-media.com/lodging/1000000/40000/37700/37651/34148478.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites St. Louis Union Station [](https://www.expedia.ca/St-Louis-Hotels-Drury-Inn-St-Louis-At-Union-Station.h37651.Hotel-Information) Downtown West, 5.3 km from St. Louis Science Center 9.4/10 Exceptional (1,348 reviews) "Staff was super nice! Even with the renovations room was clean and the kid loved the pool!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cierra CA $223 CA $265 total includes taxes & fees Apr 16 - Apr 17 [](https://www.expedia.ca/St-Louis-Hotels-Drury-Inn-St-Louis-At-Union-Station.h37651.Hotel-Information) ![Gastropub](https://images.trvl-media.com/lodging/1000000/30000/26100/26061/24983857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/30000/26100/26061/w1020h682x1y0-97f5900d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/1000000/30000/26100/26061/c3a4349f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/26100/26061/b6ec06de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Cheshire [](https://www.expedia.ca/St-Louis-Hotels-The-Cheshire.h26061.Hotel-Information) 3.2 km from St. Louis Science Center 8.6/10 Excellent (1,007 reviews) "Bar and restaurant were both great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $213 CA $253 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/St-Louis-Hotels-The-Cheshire.h26061.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/25bc97a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Bathtub, Corner](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/0864b113.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/b624c396.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/8ea3622b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Angad Arts Hotel St. Louis, Tapestry Collection by Hilton [](https://www.expedia.ca/St-Louis-Hotels-Angad-Arts-Hotel-St-Louis.h27616925.Hotel-Information) 3.7 km from St. Louis Science Center 8.8/10 Excellent (1,052 reviews) "Room was absolutely beautiful, very clean and spacious!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shawnica CA $182 CA $214 total includes taxes & fees May 3 - May 4 [](https://www.expedia.ca/St-Louis-Hotels-Angad-Arts-Hotel-St-Louis.h27616925.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-21&endDate=2026-04-22®ionId=502861&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels close to St. Louis Science Center | Property | Star rating | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | | | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | --------------------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1430000/1427900/1427801/cca43ba9.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hampton Inn & Suites St. Louis at Forest Park | 2.5 star property | 9.2Wonderful1,007 reviews | View | | | | | | | ![Lobby](https://images.trvl-media.com/lodging/2000000/1720000/1717400/1717380/6d4358f6.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Drury Inn & Suites St. Louis Forest Park | 3.0 star property | 9.4Exceptional1,009 reviews | View | | | | | | | ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/470000/465800/465749/9bee4fd7.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium) The Royal Sonesta Chase Park Plaza St. Louis | 4.5 star property | 9.0Wonderful1,009 reviews | View | | | | | | | ![Lobby](https://images.trvl-media.com/lodging/72000000/71090000/71082600/71082568/937991c0.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)AC Hotel St. Louis Central West End | 4.0 star property | 9.0Wonderful731 reviews | View | | | | | | | ![Terrace/patio](https://images.trvl-media.com/lodging/11000000/10510000/10503100/10503041/c6cc2b03.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Home2 Suites by Hilton St. Louis/Forest Park | 3.0 star property | 8.6Excellent1,011 reviews | View | | | | | | ## Top St. Louis Science Center Hotel Reviews ![DoubleTree by Hilton St. Louis Forest Park](https://images.trvl-media.com/lodging/2000000/1090000/1082400/1082373/ce4899f0_y.jpg) ### DoubleTree by Hilton St. Louis Forest Park 10/10 Excellent "Room was quite large and nice" [](https://expedia.ca/St-Louis-Hotels-DoubleTree-By-Hilton-St-Louis-Forest-Park.h1082373.Hotel-Information) ![Hotel Indigo St Louis - Central West End by IHG](https://images.trvl-media.com/lodging/1000000/30000/22100/22068/bd89b9ce_y.jpg) ### Hotel Indigo St Louis - Central West End by IHG 6/10 Okay "The hotel was the nice the staff was not." [](https://expedia.ca/St-Louis-Hotels-Holiday-Inn-Express-St-Louis-Central-West-End.h22068.Hotel-Information) ![Aloft St. Louis Cortex](https://images.trvl-media.com/lodging/50000000/49300000/49290300/49290300/4ca8b2dd_y.jpg) ### Aloft St. Louis Cortex 10/10 Excellent "Near specialty hospitals, very clean, great for families, has a gym, pool, beautiful pit. Staff is wonderful. " [](https://expedia.ca/St-Louis-Hotels-Aloft-St-Louis-Cortex.h49290300.Hotel-Information) ![Pear Tree Inn St. Louis Near Union Station](https://images.trvl-media.com/lodging/1000000/30000/26600/26572/3056142b_y.jpg) ### Pear Tree Inn St. Louis Near Union Station 6/10 Okay "My kids appreciated the pool (crowded as it was!). The happy hour and fountain soda in the breakfast area was a pleasant surprise. Rooms are a bit worn, hallway looked like it had some water issues as well with missing tiles/exposed pipes. Bed was too soft for me. We had to switch rooms due to wet carpet by the AC; staff was very accommodating, but it was an inconvenience after we had unpacked." [](https://expedia.ca/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Near-Union-Station.h26572.Hotel-Information) ![Forest Park Hotel by MDR](https://images.trvl-media.com/lodging/1000000/30000/22300/22298/460db328_y.jpg) ### Forest Park Hotel by MDR 10/10 Excellent "It was great, no complaints! A great property, quiet and clean!" [](https://expedia.ca/St-Louis-Hotels-Holiday-Inn-St-Louis-Forest-Park.h22298.Hotel-Information) ![The West End](https://images.trvl-media.com/lodging/107000000/106720000/106715700/106715696/74ffd1da_y.jpg) ### The West End 10/10 Excellent "There are a couple fast-food restaurants nearby. There is a grocery store almost across the street, I walked to it. The room had a small fridge and microwave and since I was trying to save money and calories, I bought food at the grocery store and made my meals in the room. However, I did see a full kitchen that you may be able to use in the common area as well. " [](https://expedia.ca/St-Louis-Hotels-The-West-End.h106715696.Hotel-Information) ![Hampton Inn & Suites St. Louis at Forest Park](https://images.trvl-media.com/lodging/2000000/1430000/1427900/1427801/cca43ba9_y.jpg) ### Hampton Inn & Suites St. Louis at Forest Park 10/10 Excellent "Amazing suite room! Absolutely loved my stay! " [](https://expedia.ca/St-Louis-Hotels-Hampton-Inn-Suites-St-Louis-At-Forest-Park.h1427801.Hotel-Information) ![ The Royal Sonesta Chase Park Plaza St. Louis](https://images.trvl-media.com/lodging/1000000/470000/465800/465749/9bee4fd7_y.jpg) ### The Royal Sonesta Chase Park Plaza St. Louis 10/10 Excellent "Beautiful hotel - three phenomenal restaurants. Perfect location. We absolutely love The Chase Park Plaza. " [](https://expedia.ca/St-Louis-Hotels-The-Chase-Park-Plaza-Royal-Sonesta-St-Louis.h465749.Hotel-Information) ![Drury Inn & Suites St. Louis Forest Park](https://images.trvl-media.com/lodging/2000000/1720000/1717400/1717380/6d4358f6_y.jpg) ### Drury Inn & Suites St. Louis Forest Park 10/10 Excellent "na" [](https://expedia.ca/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Forest-Park.h1717380.Hotel-Information) ## Hotels near other St. Louis Science Center attractions ![](https://images.trvl-media.com/place/553248635823456129/31a7e052-df36-4de6-ab04-772d1de8c62d.jpg) ### Jewel Box Made of stacked glass in a restored art deco style, this glass house from the 1930s continues to flourish with tropical trees, hanging plants and a large fountain. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635823456129) ![Grand Basin looking from top of Art Hill in Forest Park, St. Louis, Missouri](https://images.trvl-media.com/place/6005687/6a48afd8-f12d-4336-91f1-21e5f7dcf5c4.jpg) ### Forest Park 4.6/5 (3,388 reviews) Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6005687) ![](https://images.trvl-media.com/place/553248635810227311/1a3c426c-0102-47a7-a244-05819335714b.jpg) ### Pagoda Circle As one of the cornerstones of Forest Park for about a century, this grassy island and its bandstand offer an excellent concert spot. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635810227311) ![](https://images.trvl-media.com/place/6064093/1bd978a5-c785-4881-8a2a-edf6f08f40b8.jpg) ### The Muny Theater You can enjoy a show at The Muny Theater during your trip to St. Louis. Amble around the area's lush forest or attend a sporting event. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6064093) ![Caption---- Penguins at The St. Louis, MO Zoo](https://images.trvl-media.com/place/502878/d236ddaf-a463-4f53-858a-6c1f9c4e02c5.jpg) ### St. Louis Zoo 4.6/5 (4,364 reviews) In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=502878) ![](https://images.trvl-media.com/place/553248635892175015/13d907a2-8beb-4737-a54b-b19884e5d716.jpg) ### Cabanne House Attend a private wedding or musical rehearsal in the historic setting of the first brick farmhouse built west of the Mississippi River. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635892175015) ![](https://images.trvl-media.com/place/553248621555612614/f5c81b46-6015-49d2-9ee5-a58e9186f716.jpg) ### World Chess Hall of Fame Play a game of chess on a giant outdoor board, inspect chess-related artifacts and view artworks inspired by the two-player board game at this fascinating center. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621555612614) ### Highlands Golf & Tennis Center Catch an event at Highlands Golf & Tennis Center during your trip to St. Louis. Experience the area's acclaimed theater scene or attend a baseball game. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=941624749059428352) ## Frequently asked questions ### What's the area like around St. Louis Science Center? ### Where is the best place to stay near St. Louis Science Center? ### How many hotels will I be able to find near St. Louis Science Center? ### If I need to cancel the hotel reservation for my stay near St. Louis Science Center, will I receive a refund? ### What can I see and do near St. Louis Science Center? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - [5 Star Hotels in Skinker DeBaliviere ](https://www.expedia.ca/5Star-Skinker-DeBaliviere-St-Louis-Hotels.s50-n887273043026735104-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in The Grove ](https://www.expedia.ca/5Star-The-Grove-St-Louis-Hotels.s50-n808797266555363328-0.Travel-Guide-Filter-Hotels) - [Academy - Sherman Park Hotels ](https://www.expedia.ca/Academy-Sherman-Park-St-Louis-Hotels.0-n553248635976472137-0.Travel-Guide-Filter-Hotels) - 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