Title: Hotels by La Quinta Inn & Suites in Santee from CA $127 | Expedia.ca [Santee Travel Guide](https://expedia.ca/Santee.dx6678)[Hotels in Santee](https://expedia.ca/Santee-Hotels.d6678.Travel-Guide-Hotels)[Vacation Rentals in Santee](https://expedia.ca/Santee-Vacation-Rentals.d6678.Travel-Guide-VacationRentals)[Flights to Santee](https://expedia.ca/Cheap-Flights-To-Santee.d6678.Travel-Guide-Flights)[Things to do in Santee](https://expedia.ca/Things-To-Do-In-Santee.d6678.Travel-Guide-Activities)[Santee Car Rentals](https://expedia.ca/Car-Rentals-In-Santee.d6678.Car-Rental-Guide)[Santee Vacation Packages](https://expedia.ca/Santee.d6678.Destination-Travel-Guides) ![](https://images.trvl-media.com/place/3073/47ddac67-5969-41c0-8843-96304c5986bd.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by La Quinta Inn & Suites in Santee from CA $127 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 18 - Dec 19](https://www.expedia.ca/Hotel-Search?regionId=6678&startDate=2025-12-18&endDate=2025-12-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 19 - Dec 20](https://www.expedia.ca/Hotel-Search?regionId=6678&startDate=2025-12-19&endDate=2025-12-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6678&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6678&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santee La Quinta Inn & Suites ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/20000/11400/11366/b2f86861.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11400/11366/87139cb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/20000/11400/11366/e912e2a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/20000/11400/11366/3e11c449.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham San Diego Mission Bay [](https://www.expedia.ca/San-Diego-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Diego-Mission-Bay.h11366.Hotel-Information) Pacific Beach 8.0/10 Very good (1431) "Great place We will stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Derek CA $125 CA $143 total includes taxes & fees Jan 7 - Jan 8, 2026 [](https://www.expedia.ca/San-Diego-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Diego-Mission-Bay.h11366.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/5700/5684/49f2cd82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/5700/5684/8ae9b43e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5700/5684/4b32319c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/5700/5684/0d512cb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn by Wyndham San Diego - Miramar [](https://www.expedia.ca/San-Diego-Hotels-La-Quinta-Inn-By-Wyndham-San-Diego-Miramar.h5684.Hotel-Information) Rancho Peñasquitos 7.8/10 Good (1101) "It was a great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cherie CA $110 CA $127 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/San-Diego-Hotels-La-Quinta-Inn-By-Wyndham-San-Diego-Miramar.h5684.Hotel-Information) ![Free continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/22900/22810/079ae4ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/22900/22810/4e7175aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22900/22810/bfd1ccfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/22900/22810/be33bca1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn by Wyndham San Diego Chula Vista [](https://www.expedia.ca/Chula-Vista-Hotels-La-Quinta-Inn-By-Wyndham-San-Diego-Chula-Vista.h22810.Hotel-Information) Chula Vista 8.6/10 Excellent (1492) "Everything was great, staff , Room , clean , great place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Luis CA $138 CA $151 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Chula-Vista-Hotels-La-Quinta-Inn-By-Wyndham-San-Diego-Chula-Vista.h22810.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-01&endDate=2026-01-02®ionId=6678&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Hotels-La-Quinta-Inn-Suites.0-0-d6678--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Hotels-La-Quinta-Inn-Suites.0-0-d6678--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) ## Top Santee Hotel Reviews ![Wyndham San Diego Bayside](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "Fantastic location for catching a cruise. Right across the street!!! Great views as well! " [](https://expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Best Western Plus Marina Gateway Hotel](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe_y.jpg) ### Best Western Plus Marina Gateway Hotel 10/10 Excellent "Nice room and beds" [](https://expedia.ca/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ![Hard Rock Hotel San Diego](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Clean. Great room " [](https://expedia.ca/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Sheraton San Diego Resort](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/w4000h2662x0y0-91d299a1_y.jpg) ### Sheraton San Diego Resort 10/10 Excellent "The hotel was clean, festive and helpful. Very accommodating. I will definitely come back. " [](https://expedia.ca/San-Diego-Hotels-Sheraton-San-Diego-Hotel-And-Marina.h11109.Hotel-Information) ![Pendry San Diego](https://images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/05d0e601_y.jpg) ### Pendry San Diego 10/10 Excellent "Clean room staff gently " [](https://expedia.ca/San-Diego-Hotels-Pendry-San-Diego.h16298963.Hotel-Information) ![The DEXTRO Little Italy, BW Premier Collection](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/6fe441dd_y.jpg) ### The DEXTRO Little Italy, BW Premier Collection 10/10 Excellent "It was great " [](https://expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) ![Handlery Hotel](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/ab6ccd55_y.jpg) ### Handlery Hotel 10/10 Excellent "Staff was friendly room was very clean " [](https://expedia.ca/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information) ![Courtyard by Marriott San Diego Downtown Little Italy](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/db3040ff_y.jpg) ### Courtyard by Marriott San Diego Downtown Little Italy 10/10 Excellent "Clean rooms, friendly staff" [](https://expedia.ca/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) ![Lafayette Hotel & Club](https://images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/91a184a3_y.jpg) ### Lafayette Hotel & Club 10/10 Excellent "Our suite was beautiful and spacious. We hosted our friends in it every day and there was so much space. The decor is so festive and fun. The staff was very helpful and the valet guys were helpful. We had a nice time. Feedback: The shower water was not hot, and the shower leaked water all over the floor every time someone showered. Full length mirrors or more mirrors would be nice for multiple people being able to get ready at once. There were randoms wandering the floors and all restaurants and bars were packed with outsiders. It would be nice to have security by the stairs. And limit the number of outsiders because the people who pay to stay were having to leave the premise to get food/drinks. " [](https://expedia.ca/San-Diego-Hotels-Lafayette-Hotel.h38077738.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [5 Star Hotels in El Cajon ](https://www.expedia.ca/5Star-El-Cajon-Hotels.s50-0-d6632.Travel-Guide-Filter-Hotels) - [Hilton Hotels in Altadena ](https://www.expedia.ca/Altadena-San-Diego-Hotels-Hilton-Hotels.0-n553248635976472078-0--bHiltonHotels.Travel-Guide-Filter-Hotels) - [La Quinta Inn & Suites Hotels in Bonita ](https://www.expedia.ca/Bonita-Hotels-La-Quinta-Inn-Suites.0-0-d177687--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) - [Guest Houses in Bostonia ](https://www.expedia.ca/Bostonia-Guest-Houses.d177696-aaGuestHouses.Travel-Guide-Accommodation) - [Bostonia Hotels ](https://www.expedia.ca/Bostonia-Hotels.d177696.Travel-Guide-Hotels) - [Ranches in Bostonia ](https://www.expedia.ca/Bostonia-Ranches.d177696-aaRanches.Travel-Guide-Accommodation) - [Townhomes in Bostonia ](https://www.expedia.ca/Bostonia-Townhomes.d177696-aaTownhomes.Travel-Guide-Accommodation) - 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