Santee Vacation Rentals

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Santee vacation rentals

Adorable 1 bedroom house 8 min from La Jolla!

Adorable 1 bedroom house 8 min from La Jolla!
Bay Ho
10.0 out of 10, Exceptional, (49 reviews)
"Sparkling clean, friendly host and thoughtful layout"
United States
Griff V.
The price is CA $193
CA $350 total
includes taxes & fees
Apr 6 - Apr 7
Adorable 1 bedroom house 8 min from La Jolla!

Cozy Pacific Beach Cottage w/Bikes, Private Yard & Entrance

Cozy Pacific Beach Cottage w/Bikes, Private Yard & Entrance
Pacific Beach
9.6 out of 10, Exceptional, (54 reviews)
"Second stay and we’ll be back !! Good location, owner easy to work with, clean & tidy !!"
United States
Kevin O.
Cozy Pacific Beach Cottage w/Bikes, Private Yard & Entrance

Hilltop cabin with panoramic lake & mountain views

Hilltop cabin with panoramic lake & mountain views
Del Dios
9.4 out of 10, Exceptional, (30 reviews)
"Beautiful property, comfy cabin"
United States
Robert S.
The price is CA $184
CA $274 total
includes taxes & fees
Apr 7 - Apr 8
Hilltop cabin with panoramic lake & mountain views

Wine Country Cabin Near San Diego - on private 9 acres

Wine Country Cabin Near San Diego - on private 9 acres
Ramona
9.4 out of 10, Exceptional, (22 reviews)
"Well equipped kichenette with large toaster oven, microwave, fridge and electric griddle/hot plate was great for quick meals. We appreciated the candle and blankets available for hanging out on the deck at night. "
United States
Megan G.
Wine Country Cabin Near San Diego - on private 9 acres

Private 2 bedroom apt in new craftsman ranch!

Private 2 bedroom apt in new craftsman ranch!
Escondido
10.0 out of 10, Exceptional, (15 reviews)
"We really enjoyed our stay! The amenities were great, the view and scenery were beautiful, and the property was very family-friendly. Would definitely recommend and stay again!"
United States
Joshua D.
The price is CA $224
CA $410 total
includes taxes & fees
Apr 7 - Apr 8
Private 2 bedroom apt in new craftsman ranch!

Beautiful Normal Heights Living

Beautiful Normal Heights Living
Mid-City
10.0 out of 10, Exceptional, (79 reviews)
"Great location, nice cozy place, had everything we needed. Would definitely stay again."
United States
Sheila S.
The price is CA $347
CA $440 total
includes taxes & fees
Apr 1 - Apr 2
Beautiful Normal Heights Living

Cozy & romantic tiny house w/magnificent views, hillside pool, & adorable goats

Cozy & romantic tiny house w/magnificent views, hillside pool, & adorable goats
Del Dios
10.0 out of 10, Exceptional, (1 review)
"The view is everything! place is very cute and clean"
United States
Basel
The price is CA $236
CA $408 total
includes taxes & fees
Apr 16 - Apr 17
Cozy & romantic tiny house w/magnificent views, hillside pool, & adorable goats

Family Friendly Modern Guest House

Family Friendly Modern Guest House
Mira Mesa
10.0 out of 10, Exceptional, (14 reviews)
"Wonderful modern, clean and well-appointed property! Will definitely consider staying here in the future!"
United States
Derek W.
The price is CA $334
CA $713 total
includes taxes & fees
Apr 1 - Apr 2
Family Friendly Modern Guest House

Breathtaking retreat in the wine country on the ranch with goats you can pet!

Breathtaking retreat in the wine country on the ranch with goats you can pet!
Escondido
10.0 out of 10, Exceptional, (13 reviews)
"Gorgeous view, very responsive host. We enjoyed our stay and would recommend "
United States
Carol
The price is CA $306
CA $503 total
includes taxes & fees
Apr 16 - Apr 17
Breathtaking retreat in the wine country on the ranch with goats you can pet!

Harley Davidson Ranch Glampling & Kids Play Area

Harley Davidson Ranch Glampling & Kids Play Area
Ramona
10.0 out of 10, Exceptional, (11 reviews)
"It was a pleasure staying here! the place clean and cozy and we hope to return soon!"
United States
Flor R.
The price is CA $129
CA $339 total
includes taxes & fees
Apr 21 - Apr 22
Harley Davidson Ranch Glampling & Kids Play Area

Private Resort "La Casita" Spa and Mini Golf Course

Private Resort "La Casita" Spa and Mini Golf Course
ALPINE
10.0 out of 10, Exceptional, (26 reviews)
"Awesome Ola Vibe of Magnificent Lush Property Oasis!!!"
United States
Marcy
The price is CA $236
CA $431 total
includes taxes & fees
Apr 2 - Apr 3
Private Resort "La Casita" Spa and Mini Golf Course

'Ted' 2-bedroom cozy house in central location! 10 minutes to Balboa!

'Ted' 2-bedroom cozy house in central location! 10 minutes to Balboa!
Encanto
8.8 out of 10, Excellent, (32 reviews)
"This was a good central location and convenient to all of San Diego, both in and out of town."
United States
Samuel B.
The price is CA $118
CA $336 total
includes taxes & fees
Apr 14 - Apr 15
'Ted' 2-bedroom cozy house in central location! 10 minutes to Balboa!

Studio near San Diego attraction with amazing view

Studio near San Diego attraction with amazing view
Country Club
9.4 out of 10, Exceptional, (12 reviews)
"Was a very nice place to stay! 10/10 will be staying again sometime in the future! Felt very safe. "
United States
Kimberly g.
The price is CA $84
CA $224 total
includes taxes & fees
Apr 2 - Apr 3
Studio near San Diego attraction with amazing view

Pristine Poway Retreat

Pristine Poway Retreat
Poway
9.0 out of 10, Wonderful, (15 reviews)
"Beautiful place, responsive host and nice location. Kitchen needs pots/pans and other cooking items like a cutting board"
United States
Terri K.
The price is CA $340
CA $720 total
includes taxes & fees
Apr 1 - Apr 2
Pristine Poway Retreat

Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay

Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay
Old Town San Diego
10.0 out of 10, Exceptional, (273 reviews)
"We enjoyed our time in the back cottage. Everything we needed was available. We were able to just walk to so many sites and restaurants. Will definitely try to come back again! "
United States
Phillip
The price is CA $264
CA $335 total
includes taxes & fees
Apr 19 - Apr 20
Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay

Tranquil Private North San Diego Cottage/Guest 1 House

Tranquil Private North San Diego Cottage/Guest 1 House
Poway
9.0 out of 10, Wonderful, (34 reviews)
"Everything was wonderful. Beautiful property and hosts were great people."
United States
John K.
The price is CA $263
CA $606 total
includes taxes & fees
Apr 2 - Apr 3
Tranquil Private North San Diego Cottage/Guest 1 House

Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very good, (326 reviews)
"It is a clean place to stay and budget friendly. Unfortunately the noise from the road can make it hard to sleep."
United States
Afia
The price is CA $162
CA $183 total
includes taxes & fees
Apr 6 - Apr 7
Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Canyon View Tranquil Oasis w/ Private Pool and Dreamy Sunsets, New Backyard

Canyon View Tranquil Oasis w/ Private Pool and Dreamy Sunsets, New Backyard
San Carlos
9.4 out of 10, Exceptional, (62 reviews)
"The house was well located for us, spotless and mostly comfortable. We enjoyed our stay"
United States
Mary Ann M.
The price is CA $390
CA $1,073 total
includes taxes & fees
Apr 12 - Apr 13
Canyon View Tranquil Oasis w/ Private Pool and Dreamy Sunsets, New Backyard

Luxurious La Costa Remodel by SPA w/Steam Shower and Washer/Dryer!

Luxurious La Costa Remodel by SPA w/Steam Shower and Washer/Dryer!
La Costa
10.0 out of 10, Exceptional, (65 reviews)
"Great location comfy beds will definitely book again"
United States
Valerie E.
The price is CA $208
CA $437 total
includes taxes & fees
Apr 12 - Apr 13
Luxurious La Costa Remodel by SPA w/Steam Shower and Washer/Dryer!

Sentral Gaslamp Quarter

Sentral Gaslamp Quarter
4.0 star property
Downtown San Diego
9.4 out of 10, Exceptional, (806 reviews)
"Great location"
United States
Ethan
The price is CA $174
CA $242 total
includes taxes & fees
Apr 2 - Apr 3
Sentral Gaslamp Quarter
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Santee Hotel Reviews

Find out more about Santee

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Santee. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find a vacation rental in Santee?

Yes, there are vacation rentals where you'll be just 12.5 mi (20.1 km) from San Diego Zoo, giving you a more secluded option if you want a quieter place to stay. The shops and restaurants are several reasons why visitors like Santee. While you're here, grab a bite or have a drink at the bars.

What are some of the best vacation home rentals in Santee?

50' Ocean Front + 5 Outdoor Spaces + Dogs OK + AC: Visitors like this Santee vacation home rental. It is located on the beach and has a balcony, a barbecue grill, and air-conditioning to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family.

How many vacation rentals are there in Santee?

Expedia has 3 vacation rentals for your stay in Santee.

What’s there to see and do in Santee?

Cultural attractions include Off Broadway Live and Creation and Earth History Museum, whereas Mission Trails Regional Park and Sportsplex USA Santee are a couple of picturesque spots to enjoy the outdoors. San Diego Zoo and Mission Bay are other popular places to visit in the area.

What are vacation rentals like in Santee?

Vacation rentals are private accommodations you can stay in for several days or longer in Santee. Vacation rentals feature extras such as WiFi and washers and dryers so you'll be comfy for your stay. If you're concerned about cleanliness, a vacation rental can offer a sense of security away from shared hotel elevators and lobbies bustling with people while still allowing you to travel. You'll also have more space in a vacation rental than in a traditional hotel, which makes a vacation rental a popular choice for families.