Title: Santa Cruz Vacation Home Rentals from CA $110: Search Top Private Vacation Homes for Rent | Expedia.ca

[Hotels in Santa Cruz](https://expedia.ca/Santa-Cruz-Hotels.d6047957.Travel-Guide-Hotels)[Vacation Rentals in Santa Cruz](https://expedia.ca/Santa-Cruz-Vacation-Rentals.d6047957.Travel-Guide-VacationRentals)[Santa Cruz Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Cruz.d6047957.Car-Rental-Guide)[Santa Cruz Vacation Packages](https://expedia.ca/Santa-Cruz.d6047957.Destination-Travel-Guides)

![Rows of vineyards, Santa Cruz, Chile](https://images.trvl-media.com/place/6047957/e58d3014-ef10-4c60-9e03-08890e2f5494.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Mar 6 - Mar 8](https://www.expedia.ca/Hotel-Search?regionId=6047957&startDate=2026-03-06&endDate=2026-03-08&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Apr 17 - Apr 19](https://www.expedia.ca/Hotel-Search?regionId=6047957&startDate=2026-04-17&endDate=2026-04-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 15 - May 17](https://www.expedia.ca/Hotel-Search?regionId=6047957&startDate=2026-05-15&endDate=2026-05-17&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jun 12 - Jun 14](https://www.expedia.ca/Hotel-Search?regionId=6047957&startDate=2026-06-12&endDate=2026-06-14&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Santa Cruz vacation homes

![Exterior](https://images.trvl-media.com/lodging/39000000/38120000/38118300/38118253/48553e33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/39000000/38120000/38118300/38118253/a038bdc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, WiFi](https://images.trvl-media.com/lodging/39000000/38120000/38118300/38118253/4fb40573.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/39000000/38120000/38118300/38118253/da1d039e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The ambush. Field and comfort

[](https://www.expedia.ca/Santa-Cruz-Hotels-The-Ambush-Field-And-Comfort.h38118253.Hotel-Information)

Santa Cruz

CA $202

CA $269 total

Mar 18 - Mar 19

[](https://www.expedia.ca/Santa-Cruz-Hotels-The-Ambush-Field-And-Comfort.h38118253.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/124000000/123780000/123777400/123777358/58ef3ff1_edited_6d5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/124000000/123780000/123777400/123777358/ddfe58f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Iron/ironing board, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/124000000/123780000/123777400/123777358/b09f5fdb_edited_2c1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/124000000/123780000/123777400/123777358/9abb34f0_edited_f464.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Beautiful 5-bedroom home near Santa Cruz perfect for your getaway

[](https://www.expedia.ca/Peralillo-Hotels-Beautiful-5-Bedroom-Home-Near-Santa-Cruz-Perfect-For-Your-Getaway.h123777358.Hotel-Information)

Santa Cruz

CA $552

CA $647 total

Feb 23 - Feb 24

[](https://www.expedia.ca/Peralillo-Hotels-Beautiful-5-Bedroom-Home-Near-Santa-Cruz-Perfect-For-Your-Getaway.h123777358.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/94000000/93190000/93188700/93188687/db0556a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, soap, shampoo](https://images.trvl-media.com/lodging/94000000/93190000/93188700/93188687/b6b66859.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/94000000/93190000/93188700/93188687/3f23d36b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cookware/dishes/utensils](https://images.trvl-media.com/lodging/94000000/93190000/93188700/93188687/33c91c4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hostel Turismo San Vicente Tagua Tagua

[](https://www.expedia.ca/San-Vicente-Hotels-Hostel-Turismo-San-Vicente-Tagua-Tagua.h93188687.Hotel-Information)

San Vicente de Taguatagua

CA $74

CA $110 total

Feb 18 - Feb 19

[](https://www.expedia.ca/San-Vicente-Hotels-Hostel-Turismo-San-Vicente-Tagua-Tagua.h93188687.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-03&endDate=2026-03-04&regionId=6047957&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

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## Find vacation rentals that suit your style

Cabins

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Cruz%2C+O%27Higgins+Region%2C+Chile&regionId=6047957&latLong=-34.640343%2C-71.365997&adults=2&startDate=2026-05-18&d1=2026-05-18&endDate=2026-05-21&d2=2026-05-21&lodging=CABIN)

Apartments

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Cruz%2C+O%27Higgins+Region%2C+Chile&regionId=6047957&latLong=-34.640343%2C-71.365997&adults=2&startDate=2026-05-18&d1=2026-05-18&endDate=2026-05-21&d2=2026-05-21&lodging=APARTMENT)

Private vacation homes

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Cruz%2C+O%27Higgins+Region%2C+Chile&regionId=6047957&latLong=-34.640343%2C-71.365997&adults=2&startDate=2026-05-18&d1=2026-05-18&endDate=2026-05-21&d2=2026-05-21&lodging=VACATION_HOME)

Cottages

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Cruz%2C+O%27Higgins+Region%2C+Chile&regionId=6047957&latLong=-34.640343%2C-71.365997&adults=2&startDate=2026-05-18&d1=2026-05-18&endDate=2026-05-21&d2=2026-05-21&lodging=COTTAGE)

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## Top Santa Cruz Hotel Reviews

![TerraViña](https://images.trvl-media.com/lodging/4000000/3780000/3775300/3775207/08e2ca8e_y.jpg)

### TerraViña

10/10 Excellent

"Everything was wonderful and all staff were very helpful "

[](https://expedia.ca/San-Fernando-Hotels-TerraVina.h3775207.Hotel-Information)

![Santa Cruz Plaza](https://images.trvl-media.com/lodging/2000000/1410000/1406700/1406642/3fe1c8d9_y.jpg)

### Santa Cruz Plaza

10/10 Excellent

"Very clean and staff very courteous "

[](https://expedia.ca/San-Fernando-Hotels-Santa-Cruz-Plaza.h1406642.Hotel-Information)

![Hotel Vendimia Parador](https://images.trvl-media.com/lodging/23000000/22440000/22438600/22438533/2c7a7923_y.jpg)

### Hotel Vendimia Parador

10/10 Excellent

"Our stay was spectacular! Our host Mauricio and his family were welcoming and accommodating. It felt glorious to stroll around the grounds and pick fruit and even almonds! Our room was spacious with a private balcony, and the house was gorgeous with antique furniture and decor everywhere. This is a Must Stay! "

[](https://expedia.ca/San-Fernando-Hotels-Hotel-Vendimia-Parador.h22438533.Hotel-Information)

![Hotel Boutique Solaz Bella Vista de Colchagua](https://images.trvl-media.com/lodging/5000000/4250000/4248400/4248321/437299fa_y.jpg)

### Hotel Boutique Solaz Bella Vista de Colchagua

10/10 Excellent

"The hotel was in a great location and the garden and pool made it a very relaxing place to stay. All the staff were so friendly and helpful - they had given great advice before we arrived and booked wine tours for us which made our stay all the more enjoyable! Breakfast was also really good. We would certainly stay here again. "

[](https://expedia.ca/San-Fernando-Hotels-Hotel-Boutique-Solaz-Bella-Vista-De-Colchagua.h4248321.Hotel-Information)

![La Perla Hotel](https://images.trvl-media.com/lodging/19000000/18060000/18057500/18057456/afe65d1c_y.jpg)

### La Perla Hotel

10/10 Excellent

"Beautiful grounds, friendly and helpful staff."

[](https://expedia.ca/San-Fernando-Hotels-La-Perla-Hotel.h18057456.Hotel-Information)

![Casa Calfu](https://images.trvl-media.com/lodging/20000000/19900000/19897100/19897092/068ad3e4_y.jpg)

### Casa Calfu

10/10 Excellent

"This was a beautiful place to stay. Great to have the pool. The breakfast was delicious, excellent location and lovely staff. I wish we could have stayed longer but we were at the end of our travels. "

[](https://expedia.ca/San-Fernando-Hotels-Casa-Calfu-Hostal-Bed-And-Breakfast.h19897092.Hotel-Information)

![Hotel Boutique Vendimia Premium](https://images.trvl-media.com/lodging/3000000/2960000/2959500/2959484/e99bf923_y.jpg)

### Hotel Boutique Vendimia Premium

10/10 Excellent

"A comfortable, family run friendly place to stay. It's a bit quirky, and full of interesting memorabilia, but just perfect for us, with a swimming pool and a couple of excellent restaurants within 1 min walking for dinner. Spot on."

[](https://expedia.ca/San-Fernando-Hotels-Hotel-Boutique-Vendimia-Premium.h2959484.Hotel-Information)

![Colchagua Tiny Lodge](https://images.trvl-media.com/lodging/113000000/112020000/112019700/112019659/a6261078_y.jpg)

### Colchagua Tiny Lodge

10/10 Excellent

"Cute lodge with friendly staff that helps you to your cozy room- sets up your hot tub and brings an amazing basket for breakfast! Can’t wait to go back "

[](https://expedia.ca/Santa-Cruz-Hotels-Colchagua-Tiny-Lodge.h112019659.Hotel-Information)

![Hotel Boutique Grand Cru](https://images.trvl-media.com/lodging/112000000/111720000/111717800/111717705/60f6a89d_y.jpg)

### Hotel Boutique Grand Cru

10/10 Excellent

"We thoroughly enjoyed our time with the great people who own and manage this hidden gem."

[](https://expedia.ca/Santa-Cruz-Hotels-Hotel-Boutique-Grand-Cru.h111717705.Hotel-Information)

## Find out more about Santa Cruz

## Santa Cruz Vacation Homes information

| Number of reviews |                  |
| ----------------- | ---------------- |
| Accommodation     | 5 Vacation Homes |
| Lowest Price      | CA $110          |
| Highest Price     | CA $269          |