Title: Book the Best Panama Canal Zone SPA Resorts from CA $164 - Spa Hotels in Panama Canal Zone | Expedia.ca [Panama Canal Zone Travel Guide](https://expedia.ca/Panama-Canal-Zone.dx6222968)[Hotels in Panama Canal Zone](https://expedia.ca/Panama-Canal-Zone-Hotels.d6222968.Travel-Guide-Hotels)[Vacation Rentals in Panama Canal Zone](https://expedia.ca/Panama-Canal-Zone-Vacation-Rentals.d6222968.Travel-Guide-VacationRentals)[Flights to Panama Canal Zone](https://expedia.ca/Cheap-Flights-To-Panama-Canal-Zone.d6222968.Travel-Guide-Flights)[Panama Canal Zone Car Rentals](https://expedia.ca/Car-Rentals-In-Panama-Canal-Zone.d6222968.Car-Rental-Guide)[Panama Canal Zone Vacation Packages](https://expedia.ca/Panama-Canal-Zone.d6222968.Destination-Travel-Guides) ![0_BU000512](https://images.trvl-media.com/place/6222968/089e46e9-cc78-4d6b-b43a-af08a95dd797.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6222968/089e46e9-cc78-4d6b-b43a-af08a95dd797.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Panama Canal Zone Spa Hotels Tonight [Feb 21 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=6222968&startDate=2026-02-21&endDate=2026-02-22&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 22 - Feb 23](https://www.expedia.ca/Hotel-Search?regionId=6222968&startDate=2026-02-22&endDate=2026-02-23&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 27 - Mar 1](https://www.expedia.ca/Hotel-Search?regionId=6222968&startDate=2026-02-27&endDate=2026-03-01&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Mar 6 - Mar 8](https://www.expedia.ca/Hotel-Search?regionId=6222968&startDate=2026-03-06&endDate=2026-03-08&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Panama Canal Zone hotels with a spa ![Couples treatment rooms, Turkish bath, body treatments](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/46a37de3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/1a303895.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach/ocean view](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/665077af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/53f67005.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Colon 2,000 Hotel & Casino [](https://www.expedia.ca/Colon-Hotels-Radisson-Colon-2.h2147349.Hotel-Information) Barrio Sur 8.2/10 Very good (866 reviews) "Staff was very friendly and accommodating. I really enjoyed the breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Helene CA $149 CA $164 total includes taxes & fees Mar 13 - Mar 14 [](https://www.expedia.ca/Colon-Hotels-Radisson-Colon-2.h2147349.Hotel-Information) ![Sports massages, massages](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/4d4be0f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:30 AM to 7:00 PM, sun loungers](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/4df4233d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/a46475aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/e5f9d9ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SAND DIAMOND HOTEL [](https://www.expedia.ca/Colon-Hotels-SAND-DIAMOND-HOTEL.h66722954.Hotel-Information) Colon 8.6/10 Excellent (227 reviews) "Great hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) DIANA CA $163 CA $179 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Colon-Hotels-SAND-DIAMOND-HOTEL.h66722954.Hotel-Information) ![Outdoor pool, open 7:00 AM to 10:30 PM, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/b7e843b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool views, serves lunch and dinner](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/700fef33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/dc6a5657.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/d73825f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riande Aeropuerto Hotel & Casino [](https://www.expedia.ca/Tocumen-Hotels-Riande-Aeropuerto-Hotel-Casino.h26240.Hotel-Information) Tocumen 8.6/10 Excellent (1,854 reviews) "Very nice staff and confortable stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MARIA CA $171 CA $188 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Tocumen-Hotels-Riande-Aeropuerto-Hotel-Casino.h26240.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/79004c32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/8f2104c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Urban Suite,1 King, Partial City view](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/0b373179.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/1175365b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### W Panama [](https://www.expedia.ca/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) Bella Vista 9.0/10 Wonderful (1,001 reviews) "Second time staying and it was flawless." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anthony CA $294 CA $324 total includes taxes & fees Mar 7 - Mar 8 [](https://www.expedia.ca/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/398706e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/w5759h3838x0y0-d4c8ab5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/4edef1fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/616200e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Panama City [](https://www.expedia.ca/Panama-City-Hotels-Hyatt-Regency-Panama-City.h111843270.Hotel-Information) Bella Vista 9.8/10 Exceptional (199 reviews) "Very clean modern rooms, spacious hotel, delicious breakfast, very friendly staff!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Sheldon CA $225 CA $247 total includes taxes & fees Mar 7 - Mar 8 [](https://www.expedia.ca/Panama-City-Hotels-Hyatt-Regency-Panama-City.h111843270.Hotel-Information) ![Couples treatment rooms, steam room, Turkish bath, body treatments](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/0b681c03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/db85bc00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch served; local and international cuisine](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/c579d87e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch served; local and international cuisine](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/ea9ff933.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City [](https://www.expedia.ca/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) Juan Diaz 9.6/10 Exceptional (666 reviews) "As usual the stay was amazing in this hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose CA $368 CA $405 total includes taxes & fees Mar 7 - Mar 8 [](https://www.expedia.ca/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) ![Executive Suite, 1 King Bed, Partial Ocean View | Bathroom](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/a71c6d5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/w3996h2667x4y0-a167c2ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 outdoor pools, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/0babe4e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/08d313d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### JW Marriott Panama [](https://www.expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) San Francisco 9.0/10 Wonderful (1,010 reviews) "Beautiful hotel, great service. Breakfast buffet is amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tamara CA $382 CA $420 total includes taxes & fees Mar 9 - Mar 10 [](https://www.expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Body treatments, aromatherapy, body wraps, body scrubs, facials](https://images.trvl-media.com/lodging/6000000/5790000/5781900/5781845/a6bfaf07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed](https://images.trvl-media.com/lodging/6000000/5790000/5781900/5781845/2fee40c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/6000000/5790000/5781900/5781845/8d6ae106.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/6000000/5790000/5781900/5781845/234e399f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Panama [](https://www.expedia.ca/Panama-City-Hotels-The-Westin-Panama.h5781845.Hotel-Information) Costa del Este 9.0/10 Wonderful (318 reviews) "Great hotel and services" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pedro CA $305 CA $335 total includes taxes & fees Mar 7 - Mar 8 [](https://www.expedia.ca/Panama-City-Hotels-The-Westin-Panama.h5781845.Hotel-Information) ![Couples treatment rooms, sauna, hot tub, Turkish bath, body treatments](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/f95b4a50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (PAB 21 per person)](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/4e948961.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, sauna, hot tub, Turkish bath, body treatments](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/58ea7ce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/22409c1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sheraton Grand Panama [](https://www.expedia.ca/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) San Francisco 8.6/10 Excellent (1,007 reviews) "Good locatiion" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Caren CA $183 CA $202 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![Couples treatment rooms, body treatments, aromatherapy](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/965d1cfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/8c9eeca6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/34e202d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/6ae0cc51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel San Felipe [](https://www.expedia.ca/Panama-City-Hotels-Hotel-San-Felipe.h100620363.Hotel-Information) Casco Viejo 9.4/10 Exceptional (302 reviews) "Great staff and Hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joshua CA $185 CA $203 total includes taxes & fees Feb 23 - Feb 24 [](https://www.expedia.ca/Panama-City-Hotels-Hotel-San-Felipe.h100620363.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-07&endDate=2026-03-08®ionId=6222968&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Choose what matters most at spa hotels in Panama Canal Zone Pool Breakfast included Hot tub 4 stars 5 stars ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=AFFINITY_SPRING_PROMO_6222968) ## Find out more about Panama Canal Zone ### Top Panama Canal Zone attractions for a relaxing vacation The Panama Canal Zone offers a unique blend of adventure and relaxation, making it an excellent choice for travellers seeking spa hotels. Begin your journey with a visit to the Miraflores Locks, where you can witness the impressive engineering of the Panama Canal while enjoying the serene views of the waterway. For nature enthusiasts, the nearby Soberanía National Park provides a lush escape with opportunities for birdwatching and hiking through its verdant trails. If you're in the mood for some local culture, the Biomuseo showcases the biodiversity of Panama and offers engaging exhibits that are perfect for families. The vibrant Amador Causeway is ideal for leisurely walks or cycling, with stunning views of the Pacific Ocean and the city skyline. To unwind after a day of exploration, retreat to one of the luxurious hotels in the area, such as the elegant Westin Playa Bonita, which features a world-class spa offering rejuvenating treatments and stunning ocean views. Here, attentive service and plush amenities ensure a pampered experience, allowing you to fully relax and recharge. ## Top Panama Canal Zone Hotel Reviews ![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/179e52b4_y.jpg) ### Sheraton Grand Panama 10/10 Excellent "That was good" [](https://expedia.ca/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "Good" [](https://expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![The Westin Playa Bonita Panama](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/6d441b5e_y.jpg) ### The Westin Playa Bonita Panama 10/10 Excellent "The room más immaculate " [](https://expedia.ca/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information) ![Hotel El Panama by Faranda Grand, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/10000/7200/7164/cfc3400a_y.jpg) ### Hotel El Panama by Faranda Grand, a member of Radisson Individuals 10/10 Excellent "Good" [](https://expedia.ca/Panama-City-Hotels-Hotel-El-Panama-By-Faranda-Grand.h7164.Hotel-Information) ![JW Marriott Panama](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg) ### JW Marriott Panama 10/10 Excellent "The room was perfect " [](https://expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg) ### Las Americas Golden Tower Panama 10/10 Excellent "Excellent staff, very friendly and knowledgeable." [](https://expedia.ca/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) ![Dreams Playa Bonita Panama - All Inclusive](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg) ### Dreams Playa Bonita Panama - All Inclusive 10/10 Excellent "Wonderful staff, good food, and an all around beautiful resort!" [](https://expedia.ca/Panama-City-Hotels-Dreams-Playa-Bonita-Panama.h12445554.Hotel-Information) ![Radisson Hotel Panama Canal](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/23e8ad44_y.jpg) ### Radisson Hotel Panama Canal 10/10 Excellent "Excellent " [](https://expedia.ca/Amador-Hotels-Radisson-Hotel-Panama-Canal.h809149.Hotel-Information) ![Waldorf Astoria Panama](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e_y.jpg) ### Waldorf Astoria Panama 10/10 Excellent "Staff was friendly and helpful. Amenities were great and location was perfect. " [](https://expedia.ca/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information)