Title: Best Hotels Near Oklahoma Frontier Drugstore Museum, Guthrie from CA $106 | Expedia.ca [Vacation Rentals in Guthrie](https://expedia.ca/Guthrie-Vacation-Rentals.d7494.Travel-Guide-VacationRentals)[Flights to Guthrie](https://expedia.ca/Cheap-Flights-To-Guthrie.d7494.Travel-Guide-Flights)[Oklahoma Frontier Drugstore Museum Car Rentals](https://expedia.ca/Car-Rentals-In-Oklahoma-Frontier-Drugstore-Museum.d928407067723894784.Car-Rental-Guide)[Oklahoma Frontier Drugstore Museum Vacations](https://expedia.ca/Oklahoma-Frontier-Drugstore-Museum-Guthrie.d928407067723894784.Vacation-Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Feb 21 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=928407067723894784&startDate=2026-02-21&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 22 - Feb 23](https://www.expedia.ca/Hotel-Search?regionId=928407067723894784&startDate=2026-02-22&endDate=2026-02-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 27 - Mar 1](https://www.expedia.ca/Hotel-Search?regionId=928407067723894784&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Mar 6 - Mar 8](https://www.expedia.ca/Hotel-Search?regionId=928407067723894784&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Oklahoma Frontier Drugstore Museum hotels ![Exterior](https://images.trvl-media.com/lodging/3000000/2860000/2858900/2858839/f3debf7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/3000000/2860000/2858900/2858839/763ab2db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2860000/2858900/2858839/137448b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom](https://images.trvl-media.com/lodging/3000000/2860000/2858900/2858839/b0d56169.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Guthrie North Edmond by IHG [](https://www.expedia.ca/Guthrie-Hotels-Holiday-Inn-Express-Suites-Guthrie.h2858839.Hotel-Information) 2.6 km from Oklahoma Frontier Drugstore Museum 8.4/10 Very good (1,000 reviews) "Nice stay for the price range! Good breakfast, friendly staff, clean room. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chad CA $108 CA $126 total includes taxes & fees Mar 10 - Mar 11 [](https://www.expedia.ca/Guthrie-Hotels-Holiday-Inn-Express-Suites-Guthrie.h2858839.Hotel-Information) ![Children's play area - indoor](https://images.trvl-media.com/lodging/1000000/20000/12700/12615/w866h647x0y0-8af0d428.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12700/12615/2697d94d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/1000000/20000/12700/12615/973b15eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/12700/12615/932451bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Territorial Inn - Guthrie [](https://www.expedia.ca/Guthrie-Hotels-Territorial-Inn-Guthrie.h12615.Hotel-Information) 2.9 km from Oklahoma Frontier Drugstore Museum 8.2/10 Very good (803 reviews) "Clean rooms, staff was incredibly nice and breakfast was delicious." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dwight [](https://www.expedia.ca/Guthrie-Hotels-Territorial-Inn-Guthrie.h12615.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/16000000/15710000/15703100/15703100/a23aae85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15710000/15703100/15703100/07de5c99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/16000000/15710000/15703100/15703100/b1ee8059.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/16000000/15710000/15703100/15703100/a4b740d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Guthrie [](https://www.expedia.ca/Guthrie-Hotels-Hampton-Inn-Suites-Guthrie.h15703100.Hotel-Information) 2.9 km from Oklahoma Frontier Drugstore Museum 8.4/10 Very good (999 reviews) "hotel is clean and very convenient access." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert CA $117 CA $135 total includes taxes & fees Mar 10 - Mar 11 [](https://www.expedia.ca/Guthrie-Hotels-Hampton-Inn-Suites-Guthrie.h15703100.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/450000/441000/440999/9a1236fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/450000/441000/440999/58934206.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/450000/441000/440999/284a90f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/450000/441000/440999/af398b47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites Guthrie - Edmond North [](https://www.expedia.ca/Guthrie-Hotels-Sleep-Inn-Suites-Guthrie-Edmond-North.h440999.Hotel-Information) 2.9 km from Oklahoma Frontier Drugstore Museum 7.8/10 Good (124 reviews) "Clean rooms, staff was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert CA $99 CA $115 total includes taxes & fees Mar 15 - Mar 16 [](https://www.expedia.ca/Guthrie-Hotels-Sleep-Inn-Suites-Guthrie-Edmond-North.h440999.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/113000000/112160000/112158800/112158721/ba7d0a15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bungalow | Private kitchen](https://images.trvl-media.com/lodging/113000000/112160000/112158800/112158721/8534b4d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House | Living area](https://images.trvl-media.com/lodging/113000000/112160000/112158800/112158721/5a3e32b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House | Living area](https://images.trvl-media.com/lodging/113000000/112160000/112158800/112158721/w2502h1876x0y0-867df7b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Judge's Chambers [](https://www.expedia.ca/Guthrie-Hotels-The-Judges-Chambers.h112158721.Hotel-Information) 1.4 km from Oklahoma Frontier Drugstore Museum 10/10 Exceptional (2 reviews) "We had a wonderful experience. The home is beautiful. We were there at Christmas time and it was beautifully decorated. Breakfast and coffee were delicious. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelli CA $227 CA $264 total includes taxes & fees Mar 24 - Mar 25 [](https://www.expedia.ca/Guthrie-Hotels-The-Judges-Chambers.h112158721.Hotel-Information) ![Soundproofing, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499358/a23af9a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499358/4d3a5abe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free self parking](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499358/8dac09af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499358/42a965ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Interstate Motel Guthrie [](https://www.expedia.ca/Guthrie-Hotels-Interstate-Motel-Guthrie.h2499358.Hotel-Information) 2.4 km from Oklahoma Frontier Drugstore Museum 6.0/10 (130 reviews) "The staff was so nice and the toom was comfortable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Briana CA $91 CA $106 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/Guthrie-Hotels-Interstate-Motel-Guthrie.h2499358.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-07&endDate=2026-03-08®ionId=928407067723894784&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels close to Oklahoma Frontier Drugstore Museum | Property | Star rating | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | | | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | ------------------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![Exterior](https://images.trvl-media.com/lodging/3000000/2860000/2858900/2858839/f3debf7c.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Holiday Inn Express & Suites Guthrie North Edmond by IHG | 2.5 star property | 8.4Very good1,000 reviews | View | | | | | | | ![Children's play area - indoor](https://images.trvl-media.com/lodging/1000000/20000/12700/12615/w866h647x0y0-8af0d428.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Territorial Inn - Guthrie | 2.5 star property | 8.2Very good803 reviews | View | | | | | | | ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/16000000/15710000/15703100/15703100/a23aae85.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hampton Inn & Suites Guthrie | 2.5 star property | 8.4Very good999 reviews | View | | | | | | | ![Lobby](https://images.trvl-media.com/lodging/1000000/450000/441000/440999/9a1236fd.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Sleep Inn & Suites Guthrie - Edmond North | 2.5 star property | 7.8Good124 reviews | View | | | | | | | ![Exterior](https://images.trvl-media.com/lodging/113000000/112160000/112158800/112158721/ba7d0a15.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)The Judge's Chambers | 3.0 star property | 10.0Exceptional2 reviews | View | | | | | | ## Top Oklahoma Frontier Drugstore Museum Hotel Reviews ![avid hotel Oklahoma City - Quail Springs by IHG](https://images.trvl-media.com/lodging/25000000/24370000/24362600/24362586/4af615bc_y.jpg) ### avid hotel Oklahoma City - Quail Springs by IHG 10/10 Excellent "Wonderful room and breakfast !! " [](https://expedia.ca/Oklahoma-City-Hotels-Avid-Hotels-Oklahoma-City-Quail-Springs.h24362586.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Oklahoma City - NW Expwy](https://images.trvl-media.com/lodging/1000000/170000/165600/165560/7d2f000e_y.jpg) ### La Quinta Inn & Suites by Wyndham Oklahoma City - NW Expwy 10/10 Excellent "Staff was so so kind and accommodating. And for the price it was in decent repair and very clean. I would take a star off for the pool/hot tub being unusable without notice, and the fore alarm in our room had a low battery several days into our stay and was very very annoyong. But the staff was so kind and helpful i dont want to lower the rating at all." [](https://expedia.ca/Oklahoma-City-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Oklahoma-City-NW-Expwy.h165560.Hotel-Information) ![Embassy Suites by Hilton Oklahoma City Northwest](https://images.trvl-media.com/lodging/1000000/30000/22200/22191/4486e5bd_y.jpg) ### Embassy Suites by Hilton Oklahoma City Northwest 10/10 Excellent "Great room and outstanding staff!" [](https://expedia.ca/Oklahoma-City-Hotels-Embassy-Suites-By-Hilton-Oklahoma-City-Northwest.h22191.Hotel-Information) ![La Quinta Inn & Suites by Wyndham OKC North - Quail Springs](https://images.trvl-media.com/lodging/2000000/1090000/1088100/1088005/w2000h1499x0y1-cce58d94_y.jpg) ### La Quinta Inn & Suites by Wyndham OKC North - Quail Springs 10/10 Excellent "Great service, we enjoyed our stay!" [](https://expedia.ca/Oklahoma-City-Hotels-La-Quinta-Inn-Suites-By-Wyndham-OKC-North-Quail-Springs.h1088005.Hotel-Information) ![Holiday Inn Stillwater - University West by IHG](https://images.trvl-media.com/lodging/3000000/2210000/2206400/2206327/58558d62_y.jpg) ### Holiday Inn Stillwater - University West by IHG 10/10 Excellent "Room was clean and the bed was very comfortable. " [](https://expedia.ca/Stillwater-Hotels-Holiday-Inn-Stillwater-University-West.h2206327.Hotel-Information) ![Hilton Garden Inn Edmond / Oklahoma City North, OK](https://images.trvl-media.com/lodging/20000000/19660000/19654000/19653984/w3839h2558x0y1-4960127b_y.jpg) ### Hilton Garden Inn Edmond / Oklahoma City North, OK 10/10 Excellent "Super clean and quiet. Room was very nice." [](https://expedia.ca/Oklahoma-City-Hotels-Hilton-Garden-Inn-Edmond-Oklahoma-City-North.h19653984.Hotel-Information) ![Garner Hotel Oklahoma City - Quail Springs by IHG](https://images.trvl-media.com/lodging/2000000/1710000/1709300/1709214/16a807cb_y.jpg) ### Garner Hotel Oklahoma City - Quail Springs by IHG 10/10 Excellent "Room was clean, staff was so sweet and very kind. We even had a fire alarm scare and the lady at the front desk was very calm and helped us all. I would definitely recommend staying here. We will also be staying here again. We added it to our favorites! " [](https://expedia.ca/Oklahoma-City-Hotels-Garner-Oklahoma-City-Quail-Springs.h1709214.Hotel-Information) ![Aloft Oklahoma City Quail Springs](https://images.trvl-media.com/lodging/71000000/70900000/70890200/70890140/4ef8fb0c_y.jpg) ### Aloft Oklahoma City Quail Springs 10/10 Excellent "Everything was very clean. And the staff was nice" [](https://expedia.ca/Oklahoma-City-Hotels-Aloft-Oklahoma-City-Quail-Springs.h70890140.Hotel-Information) ![Stratford House Inns - Edmond](https://images.trvl-media.com/lodging/11000000/10540000/10539300/10539202/2b834415_y.jpg) ### Stratford House Inns - Edmond 10/10 Excellent "Was great " [](https://expedia.ca/Oklahoma-City-Hotels-Stratford-House-Inns-Edmond.h10539202.Hotel-Information) ## Hotels near other Oklahoma Frontier Drugstore Museum attractions ### Guthrie City Hall Guthrie City Hall is just one of the places to see in Guthrie, so why not enjoy the other things to explore during your travels? Discover the area's festivals and temples. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=928407306482556928) ### Guthrie Historic District Learn about the local history of Guthrie when you spend time at Guthrie Historic District. Experience the area's festivals and live music. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=928407280928755712) ### Honor Park Honor Park is just one of the places to see in Guthrie, so why not enjoy the other things to explore during your travels? Experience the area's festivals and live music. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=928406884900487168) ### Pollard Theatre 3.9/5 (17 reviews) Enjoy a performance at Pollard Theatre, a storied theater in Guthrie. Experience the area's festivals and live music. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532647465) ### Guthrie Public Library Guthrie Public Library is just one of the places to see in Guthrie, so why not enjoy the other things to explore during your travels? Experience the area's festivals and live music. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=928407343996403712) ### Guthrie Depot You can learn about the history of Guthrie with a trip to Guthrie Depot. Experience the area's festivals and live music. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=950511771809034240) ### Jelsma Stadium Catch an event at Jelsma Stadium during your trip to Guthrie. Discover the area's festivals and temples. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=928407100934393856) ### Oklahoma Territorial Museum and Carnegie Library 4.1/5 (30 reviews) You can browse the exhibits at Oklahoma Territorial Museum and Carnegie Library, a museum with a storied past, during your travels to Guthrie. Experience the area's festivals and live music. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532647464) ## Frequently asked questions ### What's the area like around Oklahoma Frontier Drugstore Museum? ### What's the best hotel to stay near Oklahoma Frontier Drugstore Museum? ### How many hotels will I be able to find close to Oklahoma Frontier Drugstore Museum? ### If I need to cancel the hotel reservation for my stay near Oklahoma Frontier Drugstore Museum, will I receive a refund? ### What can I see and do near Oklahoma Frontier Drugstore Museum?