Title: 10 Best Hotels in Murex Lakes, Sanibel for 2026 | Expedia.ca [Vacation Rentals in Sanibel](https://expedia.ca/Sanibel-Vacation-Rentals.d9791.Travel-Guide-VacationRentals)[Flights to Sanibel](https://expedia.ca/Cheap-Flights-To-Sanibel.d9791.Travel-Guide-Flights)[Things to do in Sanibel](https://expedia.ca/Things-To-Do-In-Sanibel.d9791.Travel-Guide-Activities)[Murex Lakes Car Rentals](https://expedia.ca/Car-Rentals-In-Murex-Lakes.d553248635976468770.Car-Rental-Guide)[Murex Lakes Vacations](https://expedia.ca/Murex-Lakes.d553248635976468770.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Hotels in Murex Lakes, Sanibel - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 26 - Dec 27](https://www.expedia.ca/Hotel-Search?regionId=553248635976468770&startDate=2025-12-26&endDate=2025-12-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 27 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248635976468770&startDate=2025-12-27&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248635976468770&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=553248635976468770&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Murex Lakes hotels ![Outdoor pool, open 8:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/d961205e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/4aba0d83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/1175676c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms, River View (Balcony)](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/43311ff7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Cape Coral Resort At Marina Village [](https://www.expedia.ca/Fort-Myers-Hotels-The-Westin-Cape-Coral-Resort-At-Marina-Village.h2721880.Hotel-Information) 15.7 km from Murex Lakes 9.0/10 Wonderful (1000) "Excellent stay over Thanksgiving holiday!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicole CA $276 CA $362 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Fort-Myers-Hotels-The-Westin-Cape-Coral-Resort-At-Marina-Village.h2721880.Hotel-Information) ![View from room](https://images.trvl-media.com/lodging/93000000/92430000/92421800/92421769/ead25301.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/93000000/92430000/92421800/92421769/c1a22212.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Condo, 1 Bedroom, Patio | Living area](https://images.trvl-media.com/lodging/93000000/92430000/92421800/92421769/5e014075.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Condo, 2 Bedrooms, Patio (waterview) | Private kitchen](https://images.trvl-media.com/lodging/93000000/92430000/92421800/92421769/1f1c096d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Matlacha on Shoreview [](https://www.expedia.ca/Cape-Coral-Hotels-Matlacha-At-Shoreview.h92421769.Hotel-Information) 23.2 km from Murex Lakes 9.6/10 Exceptional (215) "Place was great. Nice and neat perfect for what i needed." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $89 CA $191 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Cape-Coral-Hotels-Matlacha-At-Shoreview.h92421769.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1640000/1632700/1632691/faba246e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/2000000/1640000/1632700/1632691/23e15eaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1640000/1632700/1632691/cda8d432.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1640000/1632700/1632691/1b9c29fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dolphin Key Resort [](https://www.expedia.ca/Fort-Myers-Hotels-Dolphin-Key-Resort.h1632691.Hotel-Information) 21 km from Murex Lakes 8.8/10 Excellent (1213) "Nice rooms, great having the bar onsite" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lee CA $109 CA $122 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/Fort-Myers-Hotels-Dolphin-Key-Resort.h1632691.Hotel-Information) ![Balcony view](https://images.trvl-media.com/lodging/2000000/1880000/1874200/1874141/70464cf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1880000/1874200/1874141/97d9230d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1880000/1874200/1874141/c30c8bed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony view](https://images.trvl-media.com/lodging/2000000/1880000/1874200/1874141/6730da26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### OYO Waterfront Hotel - Cape Coral/Fort Myers, FL [](https://www.expedia.ca/Fort-Myers-Hotels-OYO-Waterfront-Hotel-Cape-CoralFort-Myers.h1874141.Hotel-Information) 23.2 km from Murex Lakes 5.8/10 (1004) "Beautiful place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Blaine CA $90 CA $110 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Fort-Myers-Hotels-OYO-Waterfront-Hotel-Cape-CoralFort-Myers.h1874141.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1380000/1374000/1373940/ad3dbe45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/2000000/1380000/1374000/1373940/34a63ef8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1380000/1374000/1373940/bbead05f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1380000/1374000/1373940/a888b077.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL [](https://www.expedia.ca/Fort-Myers-Hotels-Hampton-Inn-Suites-Cape-CoralFort-Myers-Area.h1373940.Hotel-Information) 20.2 km from Murex Lakes 8.6/10 Excellent (1001) "The rooms were clean, staff were very friendly and accommodating." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sandra CA $167 CA $186 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Fort-Myers-Hotels-Hampton-Inn-Suites-Cape-CoralFort-Myers-Area.h1373940.Hotel-Information) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/26900/26860/ab39b98c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/26900/26860/c3c27af0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/26900/26860/3133721f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/30000/26900/26860/42ce38d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Cape Coral-Fort Myers Area by IHG [](https://www.expedia.ca/Fort-Myers-Hotels-Holiday-Inn-Express-Cape-Coral-Fort-Myers-Area.h26860.Hotel-Information) 21.2 km from Murex Lakes 9.4/10 Exceptional (1087) "Is great place to stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anastassia CA $171 CA $191 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Fort-Myers-Hotels-Holiday-Inn-Express-Cape-Coral-Fort-Myers-Area.h26860.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/49000000/48600000/48598800/48598746/e7994f9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/49000000/48600000/48598800/48598746/266d5775.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/49000000/48600000/48598800/48598746/adedfa25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite (Second Floor Only) | Private kitchen](https://images.trvl-media.com/lodging/49000000/48600000/48598800/48598746/d83ba66d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Off the Charts Inn & Out Island Resort [](https://www.expedia.ca/Fort-Myers-Hotels-Off-The-Charts-Inn-Out-Island-Resort.h48598746.Hotel-Information) 8.1 km from Murex Lakes 9.6/10 Exceptional (144) "great boutique hotel in an amazing area on Pine Island Fl. Great restaurants and bars walkable and great fishing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pat CA $244 CA $318 total includes taxes & fees Dec 30 - Dec 31 [](https://www.expedia.ca/Fort-Myers-Hotels-Off-The-Charts-Inn-Out-Island-Resort.h48598746.Hotel-Information) ![Exercise/lap pool](https://images.trvl-media.com/lodging/1000000/1000000/991200/991114/fedffc57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/1000000/991200/991114/77b83b7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/1000000/991200/991114/10e34bd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach volleyball](https://images.trvl-media.com/lodging/1000000/1000000/991200/991114/01798210.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Vacation Club at Coconut Cove, Bonita Springs [](https://www.expedia.ca/Bonita-Springs-Hotels-Hyatt-Vacation-Club-At-Coconut-Cove.h991114.Hotel-Information) 26.3 km from Murex Lakes 9.2/10 Wonderful (740) "Room great clean, staff great.loved pool" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dennis CA $283 CA $369 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/Bonita-Springs-Hotels-Hyatt-Vacation-Club-At-Coconut-Cove.h991114.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/19000000/18330000/18322900/18322806/bd1916c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/19000000/18330000/18322900/18322806/e0307224.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/19000000/18330000/18322900/18322806/0e792007.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18330000/18322900/18322806/14701c89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Fort Myers Estero [](https://www.expedia.ca/Fort-Myers-Hotels-TownePlace-Suites-By-Marriott-Fort-Myers-Estero.h18322806.Hotel-Information) 29.6 km from Murex Lakes 9.4/10 Exceptional (467) "Clean room and very nice staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nancy CA $217 CA $242 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Fort-Myers-Hotels-TownePlace-Suites-By-Marriott-Fort-Myers-Estero.h18322806.Hotel-Information) ![Outdoor pool, a heated pool, sun loungers](https://images.trvl-media.com/lodging/6000000/5430000/5427100/5427071/a9952fd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/6000000/5430000/5427100/5427071/1f6416a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/6000000/5430000/5427100/5427071/ac457bc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, a heated pool, sun loungers](https://images.trvl-media.com/lodging/6000000/5430000/5427100/5427071/b3dba413.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Resort Harbour Properties [](https://www.expedia.ca/Fort-Myers-Hotels-Resort-Harbour-Properties.h5427071.Hotel-Information) 10.8 km from Murex Lakes 9.6/10 Exceptional (364) "10/10 would stay there again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristie CA $784 CA $1,348 total includes taxes & fees Dec 27 - Dec 28 [](https://www.expedia.ca/Fort-Myers-Hotels-Resort-Harbour-Properties.h5427071.Hotel-Information) ![Deluxe Studio Suite | Terrace/patio](https://images.trvl-media.com/lodging/101000000/100010000/100004200/100004161/8edbdf92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Studio Suite | Living area](https://images.trvl-media.com/lodging/101000000/100010000/100004200/100004161/e0d72b7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Studio Suite | Private kitchen](https://images.trvl-media.com/lodging/101000000/100010000/100004200/100004161/b237ba1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Studio Suite | Living area](https://images.trvl-media.com/lodging/101000000/100010000/100004200/100004161/7b9d153c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### White Orchid Apartments [](https://www.expedia.ca/Fort-Myers-Hotels-White-Orchid-Apartments.h100004161.Hotel-Information) 15.3 km from Murex Lakes 8.0/10 Very good (49) "Place was nice and private. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dawn CA $94 CA $149 total includes taxes & fees Dec 27 - Dec 28 [](https://www.expedia.ca/Fort-Myers-Hotels-White-Orchid-Apartments.h100004161.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/w2247h1500x326y0-2ea06bb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, sun loungers, beach towels](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/6b3a0fb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/aa9b23b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/2ab8abc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sanibel Island Beach Resort [](https://www.expedia.ca/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) Mid Island, 5.3 km from Murex Lakes 9.2/10 Wonderful (1488) "Excellent value with a great location and a solid staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $333 CA $406 total includes taxes & fees Jan 8 - Jan 9, 2026 [](https://www.expedia.ca/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) ![Basic Studio | Private kitchen](https://images.trvl-media.com/lodging/102000000/101230000/101221500/101221445/1d3727b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Studio (Our Largest Unit) | Living area](https://images.trvl-media.com/lodging/102000000/101230000/101221500/101221445/ae1c6b63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Studio | Living area](https://images.trvl-media.com/lodging/102000000/101230000/101221500/101221445/56eff8cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Studio (Our Largest Unit) | Terrace/patio](https://images.trvl-media.com/lodging/102000000/101230000/101221500/101221445/fac5779b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Summerwind Studios [](https://www.expedia.ca/Fort-Myers-Hotels-Summerwind-Studios.h101221445.Hotel-Information) 17.5 km from Murex Lakes 8.0/10 Very good (11) "Very clean and roomy. Quiet neighborhood. Loves the shower; so relaxing. Only complaint is that we could have used some drinking glasses. I would stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Micki CA $95 CA $151 total includes taxes & fees Dec 27 - Dec 28 [](https://www.expedia.ca/Fort-Myers-Hotels-Summerwind-Studios.h101221445.Hotel-Information) ![Economy Studio (Turtle) | Private kitchen](https://images.trvl-media.com/lodging/113000000/112940000/112934500/112934495/6ec7a320.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Studio (HoneyBee)](https://images.trvl-media.com/lodging/113000000/112940000/112934500/112934495/d570642d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Studio (Butterfly) | Living area](https://images.trvl-media.com/lodging/113000000/112940000/112934500/112934495/9324697f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Studio (Alligator) | Living area](https://images.trvl-media.com/lodging/113000000/112940000/112934500/112934495/7a5f7b79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TriLuxe Inn & Studios [](https://www.expedia.ca/Fort-Myers-Hotels-TriLuxe-Inn-Studios.h112934495.Hotel-Information) 17.4 km from Murex Lakes 8.2/10 Very good (17) "Everything was great, will definitely be coming back" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ruben CA $97 CA $152 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Fort-Myers-Hotels-TriLuxe-Inn-Studios.h112934495.Hotel-Information) ![4 outdoor pools](https://images.trvl-media.com/lodging/1000000/800000/792100/792025/311e3874.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels](https://images.trvl-media.com/lodging/1000000/800000/792100/792025/53643806.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/800000/792100/792025/325331d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/800000/792100/792025/a634b537.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Coconut Point Resort & Spa [](https://www.expedia.ca/Naples-Hotels-Hyatt-Regency-Coconut-Point-Resort-Spa.h792025.Hotel-Information) 26.6 km from Murex Lakes 9.0/10 Wonderful (1000) "This is a fabulous hotel in every way. The staff are outstanding especially Ursula who went out of her way to make sure we had what we needed. The hotel and it’s restaurants are wonderful. It is situated in the middle of beautiful groves with its on private island. Shopping is close by." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra CA $670 CA $816 total includes taxes & fees Jan 12 - Jan 13, 2026 [](https://www.expedia.ca/Naples-Hotels-Hyatt-Regency-Coconut-Point-Resort-Spa.h792025.Hotel-Information) ![Outdoor pool, open 7:00 AM to 6:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/3000000/2450000/2443800/2443726/f927a0fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2450000/2443800/2443726/d2d1940f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cocktail bar](https://images.trvl-media.com/lodging/3000000/2450000/2443800/2443726/b5ae8df6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2450000/2443800/2443726/b4f496dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Fort Myers Estero [](https://www.expedia.ca/Fort-Myers-Hotels-Hyatt-Place-Coconut-Point.h2443726.Hotel-Information) 29.1 km from Murex Lakes 8.8/10 Excellent (1001) "Great staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marlene CA $243 CA $271 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Fort-Myers-Hotels-Hyatt-Place-Coconut-Point.h2443726.Hotel-Information) ![On the beach, white sand, kayaking, motor boating](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/ac9a3a07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/39279b5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, 3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/17d9d33f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Water view](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/4914d2c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Sanibel Harbour Resort & Spa [](https://www.expedia.ca/Fort-Myers-Hotels-Marriott-Sanibel-Harbour-Resort-Spa.h3079.Hotel-Information) 10.9 km from Murex Lakes 8.4/10 Very good (1004) "This was thr best place that we have ever stayed at. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matthew CA $436 CA $521 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Fort-Myers-Hotels-Marriott-Sanibel-Harbour-Resort-Spa.h3079.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40800/40711/55e96d4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40800/40711/925dd3c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40800/40711/09cc3103.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/50000/40800/40711/0f55ab5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sanibel Inn [](https://www.expedia.ca/Fort-Myers-Hotels-Sanibel-Inn.h40711.Hotel-Information) East End, 6.3 km from Murex Lakes 9.0/10 Wonderful (1000) "Just beautiful! Couldn’t ask for a better stay in Sanibel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer Rebecca CA $482 CA $617 total includes taxes & fees Jan 7 - Jan 8, 2026 [](https://www.expedia.ca/Fort-Myers-Hotels-Sanibel-Inn.h40711.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/27000000/26920000/26914900/26914841/3e7873b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/27000000/26920000/26914900/26914841/b7fba495.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe King Studio Waterfront](https://images.trvl-media.com/lodging/27000000/26920000/26914900/26914841/cf6a8265.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/27000000/26920000/26914900/26914841/56a5c955.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Latitude 26 Waterfront Boutique Resort - Bonita Springs [](https://www.expedia.ca/Naples-Hotels-Latitude-26-Waterfront-Boutique-Resort.h26914841.Hotel-Information) 29.2 km from Murex Lakes 8.8/10 Excellent (708) "Super location charming place, a total hidden gem!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jay CA $232 CA $265 total includes taxes & fees Jan 3 - Jan 4, 2026 [](https://www.expedia.ca/Naples-Hotels-Latitude-26-Waterfront-Boutique-Resort.h26914841.Hotel-Information) ![Luxury Suite, Sea View | Beach/ocean view](https://images.trvl-media.com/lodging/2000000/1510000/1509800/1509747/57dffb5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Suite, Sea View | Balcony view](https://images.trvl-media.com/lodging/2000000/1510000/1509800/1509747/1fdb20ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gulfview Studio](https://images.trvl-media.com/lodging/2000000/1510000/1509800/1509747/8530c714.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1510000/1509800/1509747/f9e5b71d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Island Inn [](https://www.expedia.ca/Fort-Myers-Hotels-Island-Inn.h1509747.Hotel-Information) West End, 0.8 km from Murex Lakes 9.4/10 Exceptional (1123) "Really nice, updated, and clean room with a screened waterfront balcony in a perfect place on the island (far enough away from the big resorts to be in a quieter area, but close enough to the center area of the island to be convenient). " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chris CA $354 CA $395 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Fort-Myers-Hotels-Island-Inn.h1509747.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-09&endDate=2026-01-10®ionId=553248635976468770&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in Murex Lakes Find the best Murex Lakes areas and neighborhoods for the activities you enjoy most. - West End - Mid Island - East End - Beachview Country Club Estates - Sanctuary ![Fort Myers showing a sandy beach](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/31000/31797-Sanibel-Island.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Sanibel Captiva Chamber of Commerce/Milissa Sprecher Photography ![Fort Myers which includes signage](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/31000/31796-Sanibel-Island.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Sanibel Captiva Chamber of Commerce/Milissa Sprecher Photography ![Fort Myers showing island views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/31000/31793-Sanibel-Island.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Sanibel Captiva Chamber of Commerce/Dave Meardon Photography ![Fort Myers which includes a pebble beach](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/31000/31789-Sanibel-Island.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Sanibel Captiva Chamber of Commerce/Dave Meardon Photography ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/427000/427051-Sanibel-Captiva-Island.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Sanibel Captiva Chamber of Commerce/Dave Meardon Photography [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=977664051587067904) ![West End map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:egs%60DlmrtNyjAco%40Xei%40tyAkvB_%40evB%7EfCyvG%7ExAqa%40jfC%7BAyAzo%40mFpn%40o%7D%40ncDg_%40nw%40euAn%7DAyoA%7CsCagBftA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=rYtfIojIXwdhtd9RgwR7P6VGoPQ=) ### West End While visiting West End, you might make a stop by sights like J. N. Ding Darling National Wildlife Refuge and Bowman's Beach. [See properties](https://www.expedia.ca/Hotel-Search?regionId=977664051587067904) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496800-sanibel-historical-museum-and-village.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496794-sanibel-historical-museum-and-village.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496797-sanibel-historical-museum-and-village.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496795-sanibel-historical-museum-and-village.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496033-southwest-coast-florida.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=977663677668896768) ![Mid Island map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:ivk%60Dfj%7EsNoU%7Bk%40sk%40m%5EsTlS_%5DeYmi%40%7B%5CiBiQvJ%7BUd%5B%7Be%40zP_e%40fTgRbLkPpq%40lLdi%40MnQEdb%40b%7E%40%7EWzn%40hZphArFzb%40b%40h%5DefC%60B&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=VxGJcF1rdvQCDBU5UqL_Xs8Jsy8=) ### Mid Island While visiting Mid Island, you might make a stop by sights like Periwinkle Way and Sanibel Island Southern Beach. [See properties](https://www.expedia.ca/Hotel-Search?regionId=977663677668896768) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/495000/495910-south-florida.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496810-sanibel.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496815-sanibel.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496813-sanibel.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496031-periwinkle-way.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=977663465835589632) ![East End map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:wkl%60DbmvsNsq%40kLxBsM%7EBFpByDtDqR%7D%40_DNoZaBqNm%40aNViE%7D%40uKyFcOVqExFeGpE%60A%7CDpDlFpN%7EYjj%40nOt_%40zc%40%60aAk%7B%40X&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=hlweUqTn_teHrd_l720zC5CKvf4=) ### East End While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse. [See properties](https://www.expedia.ca/Hotel-Search?regionId=977663465835589632) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496031-periwinkle-way.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496033-southwest-coast-florida.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496099-periwinkle-way.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496100-periwinkle-way.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496067-periwinkle-way.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976658737) ![Beachview Country Club Estates map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:_xi%60DnhzsN%7DF%7BKm%40qJo%60%40WcFgQsIGkFm%5BlPuInCdJrU%3Fh%40cBhAh%40vCwAve%40%7CjAuVF&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=01bhKNjFz-Z_Q0nxmzzaWzGMm0I=) ### Beachview Country Club Estates If you're spending some time in Beachview Country Club Estates, Periwinkle Way and Sanibel Island Golf Club are top sights worth seeing. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976658737) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976469368) ![Sanctuary map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7Dct%60DjfqtNcl%40iNz%40%7D%5Ef%5DeBxrAodAbBcLfV%7DAbCzGkT%60OqDlf%40wIpR%7BHnXyHlIcf%40fByCzK&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=poR-ON5_hQI0xWhU_gQlcmdLxUw=) ### Sanctuary While Sanctuary might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Blind Pass Beach and Turner Beach. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976469368) ## Top Murex Lakes Hotel Reviews ![Pink Shell Beach Resort and Marina](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/5f038ed2_y.jpg) ### Pink Shell Beach Resort and Marina 10/10 Excellent "The staff was exceptional!" [](https://expedia.ca/Fort-Myers-Hotels-Pink-Shell-Beach-Resort-And-Marina.h15603.Hotel-Information) ![DiamondHead Beach Resort](https://images.trvl-media.com/lodging/1000000/210000/200700/200632/814c4388_y.jpg) ### DiamondHead Beach Resort 10/10 Excellent "All ok" [](https://expedia.ca/Fort-Myers-Hotels-DiamondHead-Beach-Resort.h200632.Hotel-Information) ![Hyatt Vacation Club at Coconut Cove, Bonita Springs](https://images.trvl-media.com/lodging/1000000/1000000/991200/991114/fedffc57_y.jpg) ### Hyatt Vacation Club at Coconut Cove, Bonita Springs 10/10 Excellent "Both and lazy river a blast" [](https://expedia.ca/Bonita-Springs-Hotels-Hyatt-Vacation-Club-At-Coconut-Cove.h991114.Hotel-Information) ![Margaritaville Beach Resort Fort Myers ](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/w3998h2821x0y0-a77e6574_y.jpg) ### Margaritaville Beach Resort Fort Myers 10/10 Excellent "Awesome place. Definitely coming back. The room and the staff were excellent. " [](https://expedia.ca/Fort-Myers-Beach-Hotels-Margaritaville-Beach-Resort-Fort-Myers.h95126992.Hotel-Information) ![Holiday Inn Express Cape Coral-Fort Myers Area by IHG](https://images.trvl-media.com/lodging/1000000/30000/26900/26860/ab39b98c_y.jpg) ### Holiday Inn Express Cape Coral-Fort Myers Area by IHG 10/10 Excellent "Always a good stay " [](https://expedia.ca/Fort-Myers-Hotels-Holiday-Inn-Express-Cape-Coral-Fort-Myers-Area.h26860.Hotel-Information) ![Matanzas Inn Bayside Resort and Marina](https://images.trvl-media.com/lodging/3000000/2670000/2665100/2665085/fc463bf9_y.jpg) ### Matanzas Inn Bayside Resort and Marina 10/10 Excellent "We had another great stay at Matanzas Inn! The “cottage” is across the street and up a stairwell into a great studio apartment with a king bed that had a full size fridge, cooktop with 4 burners, microwave, cookware and a dishwasher. Very comfortable accommodation! The real bonus is being able to walk around and enjoy all the restaurants & bars with live music everywhere. Penny is a great lady and we look forward to our next stay here!" [](https://expedia.ca/Fort-Myers-Hotels-Matanzas-Inn-Bayside-Resort-And-Marina.h2665085.Hotel-Information) ![Edison Beach House](https://images.trvl-media.com/lodging/12000000/11760000/11753200/11753200/fb0b7d7c_y.jpg) ### Edison Beach House 10/10 Excellent "Everything was great, clean alot of space n walking distance to time square" [](https://expedia.ca/Fort-Myers-Hotels-Edison-Beach-House.h11753200.Hotel-Information) ![Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway](https://images.trvl-media.com/lodging/1000000/560000/551900/551886/8158a459_y.jpg) ### Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway 10/10 Excellent "Wonderful breakfast selection. Worth the price for the close proximity to Fort Meyer beach. " [](https://expedia.ca/Fort-Myers-Beach-Hotels-Hampton-Inn-Suites-Fort-Myers-BeachSanibel-Gateway.h551886.Hotel-Information) ![Sanibel Island Beach Resort](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/w2247h1500x326y0-2ea06bb5_y.jpg) ### Sanibel Island Beach Resort 10/10 Excellent "Restaurant staff was excellent. They catered to the special requirements we had. Direct beach access with beach chairs setup was a big plus." [](https://expedia.ca/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) ## Frequently asked questions ### What's it like in Murex Lakes? ### How many hotels are there in Murex Lakes? ### If I need to cancel my hotel reservation in Murex Lakes, will I receive a refund? ### What is there to do around this Sanibel neighborhood? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [3 Star Hotels in Sanibel Captiva Island ](https://www.expedia.ca/3Star-Sanibel-Captiva-Island-Hotels.s30-0-d6326115.Travel-Guide-Filter-Hotels) - [Hotels near Bailey - Matthews Shell Museum ](https://www.expedia.ca/Bailey-Matthews-Shell-Museum-Hotels.0-l6123901-0.Travel-Guide-Filter-Hotels) - [Hotels near Bowman's Beach ](https://www.expedia.ca/Bowmans-Beach-Hotels.0-l6296151-0.Travel-Guide-Filter-Hotels) - [Bright Water Hotels ](https://www.expedia.ca/Bright-Water-Sanibel-Hotels.0-n553248635976473851-0.Travel-Guide-Filter-Hotels) - [Hotels near Captiva Beach ](https://www.expedia.ca/Captiva-Beach-Hotels.0-l6296288-0.Travel-Guide-Filter-Hotels) - [Captiva Hotels ](https://www.expedia.ca/Captiva-Hotels.d86452.Travel-Guide-Hotels) - [Hotels near Causeway Islands Park A ](https://www.expedia.ca/Causeway-Islands-Park-A-Hotels.0-l6298744-0.Travel-Guide-Filter-Hotels) - [Hotels near Causeway Islands Park B ](https://www.expedia.ca/Causeway-Islands-Park-B-Hotels.0-l6298750-0.Travel-Guide-Filter-Hotels) - [Casino Hotels in Chateaux Sur Mer ](https://www.expedia.ca/Chateaux-Sur-Mer-Sanibel-Hotels-Casino-Hotel.0-n553248635976472800-0-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Chateaux Sur Mer Hotels ](https://www.expedia.ca/Chateaux-Sur-Mer-Sanibel-Hotels.0-n553248635976472800-0.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Gulf Pines ](https://www.expedia.ca/Gulf-Pines-Sanibel-Hotels-Oceanfront-Hotels.0-n553248635976472804-0-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Adults Only Resorts & in Gulf Shores ](https://www.expedia.ca/Gulf-Shores-Sanibel-Hotels-Adults-Only-Resorts.0-n553248635976479667-0-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Hotels with a Lazy River in Gulf Shores ](https://www.expedia.ca/Gulf-Shores-Sanibel-Hotels-Hotels-With-A-Lazy-River.0-n553248635976479667-0-tHotelswithaLazyRiver.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Gulf Shores ](https://www.expedia.ca/Gulf-Shores-Sanibel-Hotels-Hotels-With-Indoor-Pool.0-n553248635976479667-0-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Gulf Shores ](https://www.expedia.ca/Gulf-Shores-Sanibel-Hotels-Pet-Friendly-Hotel.0-n553248635976479667-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Gulf Shores Hotels ](https://www.expedia.ca/Gulf-Shores-Sanibel-Hotels.0-n553248635976479667-0.Travel-Guide-Filter-Hotels) - [Gumbo Limbo Hotels ](https://www.expedia.ca/Gumbo-Limbo-Sanibel-Hotels.0-n553248635976480905-0.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Island Woods ](https://www.expedia.ca/Island-Woods-Sanibel-Hotels-Cheap-Hotels.0-n553248635976477725-0-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels near J. 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Ding Darling National Wildlife Refuge ](https://www.expedia.ca/J-N-Ding-Darling-National-Wildlife-Refuge-Hotels.0-l6123903-0.Travel-Guide-Filter-Hotels) - [Hotels near Jensen’s Marina ](https://www.expedia.ca/Jensens-Marina-Hotels.0-l553248621533115710-0.Travel-Guide-Filter-Hotels) - [Manatee Bay Hotels ](https://www.expedia.ca/Manatee-Bay-Saint-James-City-Hotels.0-n553248635976473614-0.Travel-Guide-Filter-Hotels) - [Hotels near Periwinkle Way ](https://www.expedia.ca/Periwinkle-Way-Hotels.0-l6298863-0.Travel-Guide-Filter-Hotels) - [Hotels near Port Sanibel Marina ](https://www.expedia.ca/Port-Sanibel-Marina-Hotels.0-l6295987-0.Travel-Guide-Filter-Hotels) - [Punta Rassa Hotels ](https://www.expedia.ca/Punta-Rassa-Fort-Myers-Hotels.0-n6177558-0.Travel-Guide-Filter-Hotels) - [Saint James City Hotels ](https://www.expedia.ca/Saint-James-City-Hotels.d6355652.Travel-Guide-Hotels) - [Hotels near Sanibel and Captiva Island Visitor's Center ](https://www.expedia.ca/Sanibel-And-Captiva-Island-Visitors-Center-Hotels.0-l6295955-0.Travel-Guide-Filter-Hotels) - 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[Hotels with Tennis Courts in Sanibel Captiva Island ](https://www.expedia.ca/Sanibel-Captiva-Island-Hotels-Hotels-With-Tennis-Courts.0-0-d6326115-tHotelswithTennisCourts.Travel-Guide-Filter-Hotels) - [Hotels with Waterslides in Sanibel Captiva Island ](https://www.expedia.ca/Sanibel-Captiva-Island-Hotels-Hotels-With-Waterslides.0-0-d6326115-tHotelswithWaterslides.Travel-Guide-Filter-Hotels) - [Independent Hotels in Sanibel Captiva Island ](https://www.expedia.ca/Sanibel-Captiva-Island-Hotels-Independent.0-0-d6326115--bIndependent.Travel-Guide-Filter-Hotels) - [La Quinta Inn & Suites Hotels in Sanibel Captiva Island ](https://www.expedia.ca/Sanibel-Captiva-Island-Hotels-La-Quinta-Inn-Suites.0-0-d6326115--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Sanibel Captiva Island ](https://www.expedia.ca/Sanibel-Captiva-Island-Hotels-Luxury-Hotel.0-0-d6326115-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Noble House Hotels in Sanibel Captiva Island ](https://www.expedia.ca/Sanibel-Captiva-Island-Hotels-Noble-House.0-0-d6326115--bNobleHouse.Travel-Guide-Filter-Hotels) - 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