Title: Hotels by Motel 6 in Lupus | Expedia.ca [Lupus Travel Guide](https://expedia.ca/Lupus.dx553248634983573735)[Hotels in Lupus](https://expedia.ca/Lupus-Hotels.d553248634983573735.Travel-Guide-Hotels)[Vacation Rentals in Lupus](https://expedia.ca/Lupus-Vacation-Rentals.d553248634983573735.Travel-Guide-VacationRentals)[Flights to Lupus](https://expedia.ca/Cheap-Flights-To-Lupus.d553248634983573735.Travel-Guide-Flights)[Lupus Car Rentals](https://expedia.ca/Car-Rentals-In-Lupus.d553248634983573735.Car-Rental-Guide)[Lupus Vacation Packages](https://expedia.ca/Lupus.d553248634983573735.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Motel 6 in Lupus - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 16 - Dec 17](https://www.expedia.ca/Hotel-Search?regionId=553248634983573735&startDate=2025-12-16&endDate=2025-12-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 17 - Dec 18](https://www.expedia.ca/Hotel-Search?regionId=553248634983573735&startDate=2025-12-17&endDate=2025-12-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=553248634983573735&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248634983573735&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLupus-Hotels-Motel-6.0-0-d553248634983573735--bMotel6.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLupus-Hotels-Motel-6.0-0-d553248634983573735--bMotel6.Travel-Guide-Filter-Hotels) ## Top Lupus Hotel Reviews ![Stoney Creek Hotel Columbia](https://images.trvl-media.com/lodging/2000000/1060000/1052400/1052330/5398551a_y.jpg) ### Stoney Creek Hotel Columbia 10/10 Excellent "A clean and quiet room with warm surroundings. The staff was very friendly and helpful. Beds were comfortable and the room had a nice chair for relaxing. " [](https://expedia.ca/Columbia-Hotels-Stoney-Creek-Hotel-Columbia.h1052330.Hotel-Information) ![Ramada by Wyndham Columbia](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/77d8da33_y.jpg) ### Ramada by Wyndham Columbia 10/10 Excellent "The rooms were perf" [](https://expedia.ca/Columbia-Hotels-Ramada-By-Wyndham-Columbia.h18803.Hotel-Information) ![Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG](https://images.trvl-media.com/lodging/8000000/7680000/7678000/7677926/8a05cd33_y.jpg) ### Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG 10/10 Excellent "Breakfast hostess was so friendly! Room was clean & comfortable." [](https://expedia.ca/Columbia-Hotels-Holiday-Inn-Express-Hotel-Suites-Columbia-Univ-Area-Hwy-63.h7677926.Hotel-Information) ![Country Inn & Suites by Radisson, Columbia, MO](https://images.trvl-media.com/lodging/2000000/1660000/1658500/1658463/c8809092_y.jpg) ### Country Inn & Suites by Radisson, Columbia, MO 10/10 Excellent "Rooms were spotless! I usually stay in Marriott properties but this gave me a new perspective on hotel selection. Higher prices don’t mean cleaner hotel rooms! This property was inexpensive but much cleaner than most Marriott locations I have stayed in!! " [](https://expedia.ca/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h1658463.Hotel-Information) ![Hampton Inn & Suites Columbia at University](https://images.trvl-media.com/lodging/3000000/2010000/2009600/2009513/2702d693_y.jpg) ### Hampton Inn & Suites Columbia at University 10/10 Excellent "Room was great for what we needed, breakfast was really good, staff very friendly, location was perfect-will be back!" [](https://expedia.ca/Columbia-Hotels-Hampton-Inn-Suites-Columbia-At-University.h2009513.Hotel-Information) ![Best Western Plus Columbia Inn](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/2c317c73_y.jpg) ### Best Western Plus Columbia Inn 10/10 Excellent "Clean " [](https://expedia.ca/Columbia-Hotels-Best-Western-Plus-Columbia-Inn.h12546284.Hotel-Information) ![Drury Inn & Suites Columbia Stadium Boulevard](https://images.trvl-media.com/lodging/1000000/50000/42200/42129/3e728377_y.jpg) ### Drury Inn & Suites Columbia Stadium Boulevard 10/10 Excellent "Room was clean and staff was friendly and helpful. Easy parking and close to highway and shopping mall." [](https://expedia.ca/Columbia-Hotels-Drury-Inn-Suites-Columbia-Stadium-Boulevard.h42129.Hotel-Information) ![Drury Plaza Hotel Columbia East](https://images.trvl-media.com/lodging/22000000/21390000/21389900/21389857/3abac008_y.jpg) ### Drury Plaza Hotel Columbia East 10/10 Excellent "Love Drury! Always the best place to stay!" [](https://expedia.ca/Columbia-Hotels-Drury-Plaza-Hotel-Columbia-East.h21389857.Hotel-Information) ![Wyndham Executive Center Columbia](https://images.trvl-media.com/lodging/1000000/30000/22400/22359/86998653_y.jpg) ### Wyndham Executive Center Columbia 10/10 Excellent "Clean toom" [](https://expedia.ca/Columbia-Hotels-Holiday-Inn-Executive-Center-Columbia-Mall.h22359.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [Guest Houses in Ashland ](https://www.expedia.ca/Ashland-Guest-Houses.d3000421361-aaGuestHouses.Travel-Guide-Accommodation) - [Ashland Hotels ](https://www.expedia.ca/Ashland-Hotels.d3000421361.Travel-Guide-Hotels) - [Motels in Ashland ](https://www.expedia.ca/Ashland-Motels.d3000421361-aaMotels.Travel-Guide-Accommodation) - [Resorts in Ashland ](https://www.expedia.ca/Ashland-Resort-Hotels.d3000421361-aaResortHotels.Travel-Guide-Accommodation) - [Marriott Hotels & Resorts in Boonville ](https://www.expedia.ca/Boonville-Hotels-Marriott-Hotels-Resorts.0-0-d6775--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) - 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