Title: Hotels by Motel 6 in Lupus | Expedia.ca [Lupus Travel Guide](https://expedia.ca/Lupus.dx553248634983573735)[Hotels in Lupus](https://expedia.ca/Lupus-Hotels.d553248634983573735.Travel-Guide-Hotels)[Vacation Rentals in Lupus](https://expedia.ca/Lupus-Vacation-Rentals.d553248634983573735.Travel-Guide-VacationRentals)[Flights to Lupus](https://expedia.ca/Cheap-Flights-To-Lupus.d553248634983573735.Travel-Guide-Flights)[Lupus Car Rentals](https://expedia.ca/Car-Rentals-In-Lupus.d553248634983573735.Car-Rental-Guide)[Lupus Vacation Packages](https://expedia.ca/Lupus.d553248634983573735.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Motel 6 in Lupus - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Nov 17 - Nov 18](https://www.expedia.ca/Hotel-Search?regionId=553248634983573735&startDate=2025-11-17&endDate=2025-11-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 18 - Nov 19](https://www.expedia.ca/Hotel-Search?regionId=553248634983573735&startDate=2025-11-18&endDate=2025-11-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=553248634983573735&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=553248634983573735&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Lupus Motel 6 Hotels ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLupus-Hotels-Motel-6.0-0-d553248634983573735--bMotel6.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLupus-Hotels-Motel-6.0-0-d553248634983573735--bMotel6.Travel-Guide-Filter-Hotels) ## Top Lupus Hotel Reviews ### Baymont by Wyndham Columbia, MO 10/10 Excellent "The gravey is terrible. Everything. Else. Is good.." [](https://expedia.ca/Columbia-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Columbia.h40115.Hotel-Information) ### Ramada by Wyndham Columbia 10/10 Excellent "🤗" [](https://expedia.ca/Columbia-Hotels-Ramada-By-Wyndham-Columbia.h18803.Hotel-Information) ### Hampton Inn & Suites Columbia at University 10/10 Excellent "The room was spotless and handicapped accessible. The location is great for sporting events and ease of accessing the campus. Staff, as always, was so helpful and kind." [](https://expedia.ca/Columbia-Hotels-Hampton-Inn-Suites-Columbia-At-University.h2009513.Hotel-Information) ### Best Western Plus Columbia Inn 10/10 Excellent "Clean room. Excellent breakfast. Good staff" [](https://expedia.ca/Columbia-Hotels-Best-Western-Plus-Columbia-Inn.h12546284.Hotel-Information) ### Stoney Creek Hotel Columbia 10/10 Excellent "Friendly check in. Clean room" [](https://expedia.ca/Columbia-Hotels-Stoney-Creek-Hotel-Columbia.h1052330.Hotel-Information) ### Days Inn by Wyndham Boonville 10/10 Excellent "Yes it did " [](https://expedia.ca/Columbia-Hotels-Days-Inn-By-Wyndham-Boonville.h42233.Hotel-Information) ### Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG 10/10 Excellent "Easy parking " [](https://expedia.ca/Columbia-Hotels-Holiday-Inn-Express-Hotel-Suites-Columbia-Univ-Area-Hwy-63.h7677926.Hotel-Information) ### Country Inn & Suites by Radisson, Columbia, MO 10/10 Excellent "Clean room quiet and very friendly staff " [](https://expedia.ca/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h1658463.Hotel-Information) ### Super 8 by Wyndham Columbia East 10/10 Excellent "Great" [](https://expedia.ca/Columbia-Hotels-Super-8-By-Wyndham-Columbia-East.h1044261.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [Guest Houses in Ashland](https://www.expedia.ca/Ashland-Guest-Houses.d3000421361-aaGuestHouses.Travel-Guide-Accommodation) - 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