Book The Best Hotels in Lupus, MO for 2026 from CA $84 - Fully Refundable Options

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Our top choices for Lupus hotels

A modern office space with a meeting area featuring a large table and chairs, a purple accent wall, and a view through large windows.

A modern office space with a desk area, seating, and a hanging chair.

1. Tru By Hilton Columbia South

Columbia

Kevin M.

CA $127

CA $145 total

includes taxes & fees

Oct 21 - Oct 22

A hotel lobby with a reception desk, seating area, and a reception counter.

A hotel room with two beds, a nightstand, a lamp, and a patterned carpet.

A dining area with tables and chairs, a kitchen in the background, and a patterned carpet.

A compact hotel room with a flat-screen TV, a microwave, a refrigerator, a bench, and a small table.

2. Baymont by Wyndham Columbia, MO

Columbia

Susan

CA $87

CA $99 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a dining area, a sofa, a TV, and a view of the city.

A hotel room with a large bed, two bedside tables with lamps, a desk with a computer, and a large window offering a view of the city.

A hotel lobby with a staircase, a bar area, and seating.

A banquet hall with round tables set for a formal event, featuring a patterned carpet and a high ceiling with chandeliers.

3. Wyndham Executive Center Columbia

Columbia

Shara

CA $141

CA $160 total

includes taxes & fees

Oct 30 - Oct 31

A patio area with a fire pit, outdoor seating, and a grill.

A modern kitchen with built-in appliances, a wooden countertop, and a seating area with a chair.

A modern building with a 'park' sign, stone facade, and outdoor seating area.

A modern dining area with a long wooden table, multiple chairs, a flat-screen TV mounted on a stone wall, and a fireplace.

4. TownePlace Suites by Marriott Columbia

Columbia

Barb

CA $168

CA $192 total

includes taxes & fees

Nov 1 - Nov 2

A modern lobby with a sectional sofa, a flat-screen TV, and a glass wall offering a view of the city.

A restaurant interior with booths and tables, blue cushioned chairs, and framed pictures on the walls.

An indoor swimming pool with clear glass walls, a tiled floor, and a seating area with chairs and tables.

A hotel room with a large bed, a sofa, a desk, and a television.

5. Drury Inn & Suites Columbia Stadium Boulevard

Columbia

Joseph

CA $143

CA $161 total

includes taxes & fees

Oct 18 - Oct 19

A lobby with a reception desk, two sofas, a coffee table, and a patterned rug.

An indoor swimming pool with clear water, surrounded by white walls and a tiled floor.

A hotel room with a bed, a dining table with chairs, a sofa set, a small table, and a kitchenette.

A modern restaurant with high tables and booths, large windows, and a patterned carpet.

6. Wingate by Wyndham - Columbia

Columbia

Carlos

CA $123

CA $139 total

includes taxes & fees

Oct 25 - Oct 26

A modern living room with grey sofas, a coffee table, and a fireplace. There are framed pictures on the wall and a floor lamp.

A reception desk with a wooden finish, three pendant lights, framed artwork on the wall, and a small display case with pastries.

A hotel room with a large bed, a desk with a lamp, a kitchenette, and a bathroom.

A modern restaurant with blue cabinets, wooden tables and chairs, and a kitchen area with appliances.

7. Country Inn & Suites by Radisson, Columbia, MO

Columbia

Nadine

CA $121

CA $136 total

includes taxes & fees

Oct 25 - Oct 26

A modern interior with round tables and chairs, a bar area, and a large window offering a view of the outside.

A modern lounge area with a sofa, round tables, and chairs, a kitchen area, and large windows.

A modern lobby with a sofa, chairs, a table, a TV, and a reception desk.

A patio area with outdoor seating, a pool, and a stone building facade.

8. Best Western Plus Columbia Inn

Columbia

Shawn

CA $117

CA $132 total

includes taxes & fees

Oct 25 - Oct 26

An indoor swimming pool with clear signage indicating no lifeguard on duty and no diving.

A reception desk with a wooden finish and granite counter, a framed welcome sign, and a lamp.

A Hampton Inn & Suites hotel with a brick facade, a covered entrance, and a parking lot.

A hotel room with a bed, a bathroom with a bathtub, a bedside table with a lamp, and a thermostat on the wall.

9. Hampton Inn & Suites Columbia at University

Columbia

Jamie

CA $163

CA $184 total

includes taxes & fees

Oct 18 - Oct 19

An indoor swimming pool with wooden beams, stone walls, and artificial trees.

A rustic interior with wooden tables and chairs, a fireplace, and a stone wall.

A log cabin interior with a stone fireplace, leather sofa, and a large painting of cowboys.

A log cabin-style room with a bed, a fireplace, a stone wall, a TV, and a large window.

10. Stoney Creek Hotel Columbia

Columbia

Brett

CA $153

CA $173 total

includes taxes & fees

Oct 18 - Oct 19

A covered outdoor seating area with wooden beams and a lantern, overlooking a brick building and greenery.

A modern interior with a seating area, wooden partitions, and large windows.

A formal dining table set with crystal glassware, plates, and napkins, with a decorative crystal centerpiece.

A hotel room with a bed, a chair, a floor lamp, and a painting on the wall.

11. Courtyard by Marriott Columbia Missouri

Columbia

Jeremy

CA $162

CA $183 total

includes taxes & fees

Oct 25 - Oct 26

A hotel entrance with a covered walkway, a brick facade, and a well-lit exterior.

A large indoor swimming pool with multiple lanes, surrounded by lounge chairs and tables.

A hotel room with two desks, each with a laptop and a chair, and a small cabinet.

A lobby with four armchairs, a coffee table, and a floor lamp. There are two wall-mounted light fixtures and a decorative wall piece.

12. Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

Columbia

Jennifer

CA $163

CA $184 total

includes taxes & fees

Nov 1 - Nov 2

A spacious living area with a blue sofa, leather armchairs, and a flat-screen TV mounted on a wooden cabinet. Large windows provide a view of parked cars outside.

A hotel room with a large bed, a desk, a chair, a lamp, and a window with curtains.

A restaurant with multiple tables and chairs, a counter with a coffee machine, and a menu board.

A hotel room with a large flat-screen TV, two beds, a sofa, and a desk.

13. Comfort Suites Columbia - University Area

Columbia

Lisa

CA $140

CA $158 total

includes taxes & fees

Nov 1 - Nov 2

An indoor swimming pool with clear water, a lifeguard chair, and a sign indicating no diving allowed.

A restaurant with booths and tables, a curved ceiling, and a slogan on the wall.

A hotel room with a large bed, a desk with a television, a chair, a lamp, and a window with curtains.

A hotel room with a sofa, armchair, and a small table. There is a lamp, a bed, and a kitchenette with a sink and a microwave.

14. Holiday Inn Columbia East by IHG

Columbia

Tracy

CA $178

CA $207 total

includes taxes & fees

Oct 17 - Oct 18

A spacious bar area with high tables and chairs, a large flat-screen TV mounted on the wall, and a bar stocked with bottles.

An indoor swimming pool with a tiled floor, a glass barrier, and a lifeguard chair.

A hotel room with two beds, a large window with curtains, and a carpeted floor.

A hotel room with a sofa, a green ottoman, a desk with a lamp, and a framed cityscape picture on the wall.

15. Drury Plaza Hotel Columbia East

Columbia

Kevin

CA $145

CA $164 total

includes taxes & fees

Oct 18 - Oct 19

A spacious indoor area with multiple seating arrangements, including tables and chairs, a television, and a fireplace.

A corner sofa with two patterned pillows, a flat-screen TV on a wooden stand, and a window with curtains.

A restaurant with a counter, seating area, and large windows.

A hotel room with two beds, a desk, a TV, and a window with curtains.

16. Quality Inn & Suites Columbia I-70

Columbia

Nathan

CA $96

CA $109 total

includes taxes & fees

Nov 2 - Nov 3

A hotel room with a large bed, a separate sitting area, a bathroom with a bathtub, and a large mirror.

A reception desk with a sign that reads "RAMADA," a television, and a seating area.

A hotel room with a red accent wall, a framed world map, a white sofa, a desk with a lamp, and a door leading to another room.

A self-service breakfast bar with coffee machines, a microwave, and various food options.

17. Ramada by Wyndham Columbia

Columbia

Andrew

CA $90

CA $102 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with a bed, two bedside lamps, a nightstand, a TV, a mirror, a bathroom with a bathtub, and a large painting on the wall.

A spacious living room with a stone fireplace, a large window, and a high ceiling.

An indoor swimming pool with clear water, a changing room, and a door leading to another area.

A modern living room with a sofa, chairs, and a dining area with tables and chairs.

18. Super 8 by Wyndham Columbia East

Columbia

Roy

CA $74

CA $84 total

includes taxes & fees

Nov 8 - Nov 9

A modern hotel room with a large bed, a sofa, a wooden side table, and abstract artwork on the wall.

A modern lounge area with a large sofa, dining tables, and hanging pendant lights.

A modern hotel with a white facade and blue accents, named Springhill Suites Marriott.

A modern reception area with a wooden desk, a refrigerator stocked with beverages, and a wall decorated with hexagonal patterns.

19. SpringHill Suites by Marriott Columbia

Columbia

Janet

CA $144

CA $163 total

includes taxes & fees

Nov 8 - Nov 9

A hotel room with a bed, a desk, a kitchenette, and a bathroom.

A modern kitchen with wooden cabinets, stainless steel appliances, and a white countertop.

A modern dining area with multiple tables and chairs, a kitchen in the background, and a television mounted on the wall.

A modern lobby with a stone fireplace, comfortable seating, and a carpeted floor.

20. Staybridge Suites Columbia by IHG

Columbia

Isabelle

CA $141

CA $159 total

includes taxes & fees

Oct 25 - Oct 26

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Stay near popular Lupus attractions

Lupus Park

After visiting Lupus Park, make a plan to see the other sights and activities in Lupus.

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Top Lupus Hotel Reviews

Drury Plaza Hotel Columbia East

10/10 Excellent

"N/A"

Country Inn & Suites by Radisson, Columbia, MO

10/10 Excellent

"Stayed for work, comfortable room and beds, clean hotel"

Isle of Capri Casino Hotel Boonville & Casino - A Caesars Rewards Destination

10/10 Excellent

"Checkin was fast. Clerk was helpful. Room was clean. Able to adjust temperature n room. Casino was fun-actually won on first machine played. NO microwave in rooms. NO breakfast available onsight."

Baymont by Wyndham Columbia, MO

10/10 Excellent

"Room was clean. I did try to use the vending machine and it denied my request, gave me a dollar back in nickels so that was interesting. Staff was friendly and felt safe in the area."

The Broadway Columbia - a DoubleTree by Hilton

10/10 Excellent

"Great place to stay visiting college kids and attending games!!!"

Best Western Plus Columbia Inn

10/10 Excellent

"Clean and wonderful place to stay."

Drury Inn & Suites Columbia Stadium Boulevard

10/10 Excellent

"Very clean hotel and the entire staff are outstanding."

Hotel Blu

10/10 Excellent

"It was hard to find, due to us looking for hotel blu, and not a hotel 6 ( the sign had not changed. But overall it was clean, and quiet."

Step Back in Time Near The Missouri River

10/10 Excellent

"Very clean, awesome decor. We loved the peace and quiet, the house was clean, plenty of room, and the host, Andrew was friendly and easy to work with!"

More cheap stays in Lupus

Hotel Blu

3402 Interstate 70 Dr SE Columbia MO

CA $75

CA $85 total

Oct 13 - Oct 14

includes taxes & fees

6.6/10 (251 reviews)

Baymont by Wyndham Columbia, MO

2500 I 70 Dr Sw Columbia MO

CA $87

CA $99 total

Oct 25 - Oct 26

includes taxes & fees

8.2/10 Very good! (1,071 reviews)

Ramada by Wyndham Columbia

901 Conley Rd Columbia MO

CA $90

CA $102 total

Oct 18 - Oct 19

includes taxes & fees

Best Western Plus Columbia Inn

2904 Clark Lane Columbia MO

CA $117

CA $132 total

Oct 25 - Oct 26

includes taxes & fees

8.8/10 Excellent! (1,464 reviews)

Country Inn & Suites by Radisson, Columbia, MO

817 N Keene St Columbia MO

CA $121

CA $136 total

Oct 25 - Oct 26

includes taxes & fees

9/10 Wonderful! (1,957 reviews)

Stoney Creek Hotel Columbia

2601 S Providence Rd Columbia MO

CA $153

CA $173 total

Oct 18 - Oct 19

includes taxes & fees

Hotels in Lupus with star rating

Frequently asked questions

When is the best time to go to Lupus?

The best time to visit Lupus, Missouri, is during the spring (April to May) and autumn (September to October) months.These seasons offer pleasant weather, with mild temperatures and lower humidity, making outdoor activities and exploring the scenic Missouri River bluffs more enjoyable. Spring brings blooming wildflowers, while autumn showcases beautiful fall foliage, adding to the area's natural beauty.For those looking to participate in local agricultural events or enjoy the outdoors without the intense summer heat, these periods are ideal.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Lupus.

How much is the nightly rate at a Lupus hotel?

Prices for hotels in Lupus often vary, but you can find a great deal from CA $84 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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Missouri Vacation Rentals

Book Hotels in Lupus on Expedia.com

Find hotels in Lupus, MO from CA $84

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Lupus

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Lupus hotels

1. Tru By Hilton Columbia South

2. Baymont by Wyndham Columbia, MO

3. Wyndham Executive Center Columbia

4. TownePlace Suites by Marriott Columbia

5. Drury Inn & Suites Columbia Stadium Boulevard

6. Wingate by Wyndham - Columbia

7. Country Inn & Suites by Radisson, Columbia, MO

8. Best Western Plus Columbia Inn

9. Hampton Inn & Suites Columbia at University

10. Stoney Creek Hotel Columbia

11. Courtyard by Marriott Columbia Missouri

12. Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

13. Comfort Suites Columbia - University Area

14. Holiday Inn Columbia East by IHG

15. Drury Plaza Hotel Columbia East

16. Quality Inn & Suites Columbia I-70

17. Ramada by Wyndham Columbia

18. Super 8 by Wyndham Columbia East

19. SpringHill Suites by Marriott Columbia

20. Staybridge Suites Columbia by IHG

Stay near popular Lupus attractions

Lupus Park

Top Lupus Hotel Reviews

Drury Plaza Hotel Columbia East

Country Inn & Suites by Radisson, Columbia, MO

Isle of Capri Casino Hotel Boonville & Casino - A Caesars Rewards Destination

Baymont by Wyndham Columbia, MO

The Broadway Columbia - a DoubleTree by Hilton

Best Western Plus Columbia Inn

Drury Inn & Suites Columbia Stadium Boulevard

Hotel Blu

Step Back in Time Near The Missouri River

More cheap stays in Lupus

Hotel Blu

Baymont by Wyndham Columbia, MO

Ramada by Wyndham Columbia

Best Western Plus Columbia Inn

Country Inn & Suites by Radisson, Columbia, MO

Stoney Creek Hotel Columbia

Hotels in Lupus with star rating

Frequently asked questions

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