Top 10 Esquilino Hotel Deals

See all 276 Hotels in Esquilino
Maikol Family Guesthouse
Maikol Family Guesthouse

Piazza Vittorio Emanuele II, 138, Rome 00185

Located in Esquilino, this guesthouse is within a 10-minute walk of Santa Prassede and Basilica di Santa Maria Maggiore. …

CA$18
Napoleon Hotel
Napoleon Hotel

Piazza Vittorio Emanuele II 105, Rome 00185

4.0 out of 5.0
4.3 out of 5 (1,883 reviews)

Set in a quiet 19th century building, this family-run hotel is 500 meters from Rome's St Maria Maggiore cathedral, one …

CA$126
Laterani Suite
Laterani Suite

Piazza di San Giovanni in Laterano, 26, Rome 00184

4.1 out of 5 (132 reviews)

Located in Esquilino, this bed & breakfast is within 1 mi (2 km) of Porta Maggiore, Roman Forum, and Basilica di San Giovanni …

CA$57
Best Western Plus Hotel Milton Roma
Best Western Plus Hotel Milton Roma

Via E. Filiberto 155, Rome 00185

4.0 out of 5.0
4.1 out of 5 (1,815 reviews)

Located in Esquilino, this hotel is within a 15-minute walk of Basilica di San Giovanni in Laterano and Basilica di Santa …

CA$77
B&B In the Center You Too
B&B In the Center You Too

Via Emanuele Filiberto 50, Rome 00185

4 out of 5 (120 reviews)

Located in Esquilino, this bed & breakfast is within a 15-minute walk of Basilica di San Giovanni in Laterano and Basilica di …

CA$41
La Rotella nel Sacco
La Rotella nel Sacco

Via G. Giolitti 461, Rome 00185

4.4 out of 5 (129 reviews)

Located in Esquilino, this bed & breakfast is within 1 mi (2 km) of Porta Maggiore, Basilica di San Giovanni in Laterano, and …

CA$48
Dem Guesthouse
Dem Guesthouse

Various Addresses, Rome 00185

3.9 out of 5 (181 reviews)

Located in Esquilino, this townhouse accommodation is within 1 mi (2 km) of Colosseum and Trevi Fountain. Piazza di Spagna is …

CA$51
Best Western Hotel President
Best Western Hotel President

Via Emanuele Filiberto 173, Rome 00185

4.0 out of 5.0
4.1 out of 5 (343 reviews)

Located in Esquilino, this hotel is within 1 mi (2 km) of Porta Maggiore, Roman Forum, and Basilica di San Giovanni in …

CA$90
Happy Home 2c
Happy Home 2c

Via Rattazzi 2C, Rome

4.5 out of 5 (55 reviews)

Located in Esquilino, this bed & breakfast is within a 5-minute walk of Santa Prassede and Basilica di Santa Maria Maggiore …

CA$67
Hotel Mariano
Hotel Mariano

Piazza Manfredo Fanti 19, Rome 00185

3.0 out of 5.0
3.7 out of 5 (147 reviews)

Located in Esquilino, this hotel is within a 10-minute walk of Planeta, Basilica di Santa Maria Maggiore, and Teatro …

CA$47
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Esquilino Hotel Guide

If you’re searching for the perfect little spot to base your next Roman holiday, take a look at the hotels in Esquilino, Rome. Perched on a hillside on the edge of San Giovanni, this unassuming neighborhood is home to sights, sounds and local treasures galore. Explore the Piazza Vittorio. Try some regional specialties at the markets. Discover the city’s multicultural vibe. When you stay at an Esquilino hotel, Rome becomes your personal playground.

Esquilino hotels are also among the best spots to experience an alternative view of Roman life: a contemporary personality that extends well beyond the most heavily traveled tourist attractions. A large portion of the action happens near the Via Cavour and Termini rail station, but venture beyond these bustling central spaces for a peek at the everyday atmosphere. African eateries dot the landscape just north of Termini, and the Via Merulana is a great place for an evening stroll. For the most unforgettable experience, however, search for Esquilino hotel deals near the Piazza Vittorio. This charming space is anchored by the locally loved Mercato Esquilino, and this sprawling market is among the most amazing places in the city to shop for Middle Eastern, Asian and traditionally Italian treats.

Of course, the culinary treasures don’t stop there. The best Esquilino hotels are situated in the middle of a foodie paradise, and you could easily spend an entire week sampling specialties at the bakeries, cafes, and tucked-away eateries. Stop for an espresso on a relaxed patio, and settle in for a people-watching session. It’s a fantastic way to pass the time in true Roman style.

Can’t wait to book your Esquilino vacations? Browse the trip-planning tools at Expedia to find airfare and hotel deals, compare prices, and make your reservation. When you travel with us, Rome is in the palm of your hands.