Title: Hotels by Independent in De Soto from CA $192 | Expedia.ca [De Soto Travel Guide](https://expedia.ca/De-Soto.dx6085105)[Hotels in De Soto](https://expedia.ca/De-Soto-Hotels.d6085105.Travel-Guide-Hotels)[Vacation Rentals in De Soto](https://expedia.ca/De-Soto-Vacation-Rentals.d6085105.Travel-Guide-VacationRentals)[Flights to De Soto](https://expedia.ca/Cheap-Flights-To-De-Soto.d6085105.Travel-Guide-Flights)[De Soto Car Rentals](https://expedia.ca/Car-Rentals-In-De-Soto.d6085105.Car-Rental-Guide)[De Soto Vacation Packages](https://expedia.ca/De-Soto.d6085105.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/1f71f3ee006639c0d49d18546ddf62b5.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Jessica King # Find Hotels by Independent in De Soto from CA $192 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 31 - Nov 1](https://www.expedia.ca/Hotel-Search?regionId=6085105&startDate=2025-10-31&endDate=2025-11-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 1 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6085105&startDate=2025-11-01&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6085105&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6085105&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top De Soto Independent Hotels ![Exterior](https://images.trvl-media.com/lodging/121000000/120670000/120660300/120660300/3f8ccda8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120670000/120660300/120660300/15e1248c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/121000000/120670000/120660300/120660300/b088e0cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/121000000/120670000/120660300/120660300/edfb33bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Freshly updated bungalow near Kimmswick and major highways- Prime Location Imperial [](https://www.expedia.ca/Imperial-Hotels-Freshly-Updated-Bungalow-Near-Kimmswick-And-Major-Highways-Prime-Location.h120660300.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/107000000/106850000/106848100/106848020/b0450c68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace](https://images.trvl-media.com/lodging/107000000/106850000/106848100/106848020/555e828a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/107000000/106850000/106848100/106848020/5458231c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/107000000/106850000/106848100/106848020/dc4e06f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clifford's Country Cottage Bonne Terre 10/10 Exceptional (23) "Clifford’s Cottage is squeaky clean, expertly stocked, cozy and just off the beaten path from many area attractions. Sharon literally thought of everything and was kind enough to leave a little welcome gift for our young kids and check on us when storms came through our second night. We couldn’t have asked for a better place to stay and our kids are already asking when we can come back! Thank you for a memorable family weekend!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tabatha R. CA $175 CA $213 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Bonne-Terre-Hotels-Cliffords-Country-Cottage.h106848020.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/121000000/120040000/120038500/120038486/0efa712c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/121000000/120040000/120038500/120038486/8219c7ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/121000000/120040000/120038500/120038486/cb611ad7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Paper towels](https://images.trvl-media.com/lodging/121000000/120040000/120038500/120038486/77aa319a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### In the Country a Beautiful 2-bedroom house with its own private lake Waterloo 10/10 Exceptional (3) "Exactly as advertised!! In the country a beautiful house with it's own private lake. The host Megan was awesome. She was very proactive in ensuring we had everything we needed for our lengthy stay. " Definitely a hidden gem in the historic town of Waterloo " Looking forward to booking this location again for our future stays while visiting family. Highly recommend if your looking for some serious R.R or just want to get away from your busy life for few days. This place won't disappoint!!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Abdullah Z. CA $220 CA $352 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/In-The-County-A-Beautiful-2-Bedroom-House-With-Its-Own-Privet-Lake.h120038486.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/107000000/106170000/106166200/106166154/3c0c8aa3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, video games, books](https://images.trvl-media.com/lodging/107000000/106170000/106166200/106166154/36384156.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/107000000/106170000/106166200/106166154/72b0b744.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/107000000/106170000/106166200/106166154/f8bfa623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Newly remodeled house minutes away from downtown, golf courses + BIG back yard Farmington 9.8/10 Exceptional (20) "Our family of 5 stayed here while visiting relatives. The house is clean and comfortable. Lots of extra touches—a whole closet full of towels, coffee pods supplies for our stay, basement full with of entertainment, a cozy electric fireplace, and streaming options on TV. The bedrooms were spacious. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) RL M. CA $164 CA $330 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Farmington-Hotels-Newly-Remodeled-House-Close-To-Downtown-And-Minutes-Away-From-Golf-Courses.h106166154.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/101000000/100470000/100465300/100465272/0cb5c163.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/101000000/100470000/100465300/100465272/w1024h570x0y57-36b84305.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100470000/100465300/100465272/w1024h569x0y57-57bff386.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100470000/100465300/100465272/w1024h570x0y57-17016e83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Your home away from home in downtown, historic Farmington! Farmington 10/10 Exceptional (35) "This an excellent place to stay snd the host were great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tony M. CA $162 CA $302 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Farmington-Hotels-Your-Home-Away-From-Home-In-Downtown.h100465272.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/112000000/111430000/111424900/111424805/b956cbd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/112000000/111430000/111424900/111424805/7627f938.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/112000000/111430000/111424900/111424805/8466de35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/112000000/111430000/111424900/111424805/b6a3f5d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy 1-bedroom house with AC and WiFi in charming Farmington Farmington 10/10 Exceptional (5) "I needed a place to stay that was not a hotel and this was perfect. I made my coffee while in my PJs. Everything was comfy, clean and perfect. Will definitely use this one again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kim R. CA $107 CA $256 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Farmington-Hotels-Cozy-1-Bedroom-House-With-AC-And-WiFi-In-Charming-Farmington.h111424805.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/108000000/107460000/107451400/107451399/22c8118b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/108000000/107460000/107451400/107451399/f9215e63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/108000000/107460000/107451400/107451399/d680edd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/108000000/107460000/107451400/107451399/b743deb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations Farmington 8.6/10 Excellent (4) "Great place. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diana CA $94 CA $192 total includes taxes & fees Nov 11 - Nov 12 [](https://www.expedia.ca/Farmington-Hotels-Charming-1-Bd-House-In-Downtown-Farmington.h107451399.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/21000000/20340000/20333700/20333613/4e722bd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, coffee/tea maker](https://images.trvl-media.com/lodging/21000000/20340000/20333700/20333613/bdd28c52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/21000000/20340000/20333700/20333613/265474f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/21000000/20340000/20333700/20333613/d257cbc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stewart Acres..."Big City Close, w/ Big Country Charm" Arnold 9.6/10 Exceptional (31) "Great location to St. Louis be downtown in 20 minutes place was clean and bed was comfortable" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) mark W. [](https://www.expedia.ca/St-Louis-Hotels-Stewart-AcresBig-City-Close.h20333613.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/97000000/96770000/96763600/96763593/b35277f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/97000000/96770000/96763600/96763593/c94f48ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/97000000/96770000/96763600/96763593/f4b6dd2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/97000000/96770000/96763600/96763593/d277b2d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Downtown Kimmswick Studio~Renovated~Prime Location Imperial 10/10 Exceptional (1) "We loved our stay! The location is convenient to so many great shops and other businesses. Walking everywhere we wanted to go was quick and easy. Everything in the rental looked new and spotless." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bette M. CA $143 CA $414 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Imperial-Hotels-Downtown-Kimmswick-RoomRenovatedPrime-Location.h96763593.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/74000000/73470000/73470000/73469992/2fc67c44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/74000000/73470000/73470000/73469992/93347520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/74000000/73470000/73470000/73469992/b5064413.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, computer monitors](https://images.trvl-media.com/lodging/74000000/73470000/73470000/73469992/54de2de2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin 1 at the Pallet Factory Leadwood 9.6/10 Exceptional (34) "For an affordable retreat, we were impressed with the stay! Some of the furnishings had seen some better days but it was a mostly minor inconvenience. The bottom bunk bed was unfortunately broken when we arrived but we also understand that sometimes unexpected things just happen. No big! The amenities otherwise were very nice and we were glad they were available - e.g. outdoor shower, flat top grill, etc. The only thing that was a bit of a disappointment was the AC unit. Even though it did a... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lindsay G. CA $50 CA $219 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Park-Hills-Hotels-Relax-And-Enjoy-The-Privacy.h73469992.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-15&endDate=2025-11-16®ionId=6085105&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDe-Soto-Hotels-Independent.0-0-d6085105--bIndependent.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDe-Soto-Hotels-Independent.0-0-d6085105--bIndependent.Travel-Guide-Filter-Hotels) ## Top De Soto Hotel Reviews ![Super 8 by Wyndham Potosi](//images.trvl-media.com/lodging/1000000/160000/158800/158717/2cf60fb9_y.jpg) ### Super 8 by Wyndham Potosi 10/10 Excellent "The room was clean, front desk very friendly and price was good. I will definitely be staying again. " [](https://expedia.ca/Farmington-Hotels-Super-8-By-Wyndham-Potosi.h158717.Hotel-Information) ![Pear Tree Inn St. Louis Arnold](//images.trvl-media.com/lodging/1000000/50000/40200/40112/d33a8d98_y.jpg) ### Pear Tree Inn St. Louis Arnold 10/10 Excellent "I am scheduled for hip surgery in 3 weeks. I was grateful for an accessible room. " [](https://expedia.ca/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Arnold.h40112.Hotel-Information) ![WoodSpring Suites St. Louis Arnold](//images.trvl-media.com/lodging/3000000/2760000/2759000/2758955/6ce331bd_y.jpg) ### WoodSpring Suites St. Louis Arnold 10/10 Excellent "Location was great as was staff" [](https://expedia.ca/St-Louis-Hotels-WoodSpring-Suites-St-Louis-Arnold.h2758955.Hotel-Information) ![Quality Inn Farmington](//images.trvl-media.com/lodging/1000000/20000/18500/18482/40607ed2_y.jpg) ### Quality Inn Farmington 10/10 Excellent "It's comfortable bed and neat room that i stay all weekend but i will go back today again! Dont like drive when rain. See u soon " [](https://expedia.ca/Farmington-Hotels-Quality-Inn-Farmington.h18482.Hotel-Information) ![Drury Inn & Suites St. Louis Arnold](//images.trvl-media.com/lodging/4000000/3870000/3861200/3861101/a7778b87_y.jpg) ### Drury Inn & Suites St. Louis Arnold 10/10 Excellent "ALWAYS ENJOY OUR STAY HERE TO SEE THE GRAND KIDS" [](https://expedia.ca/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Arnold.h3861101.Hotel-Information) ![Baymont Inn and Suites by Wyndham Farmington, MO](//images.trvl-media.com/lodging/1000000/20000/16200/16153/02759b26_y.jpg) ### Baymont Inn and Suites by Wyndham Farmington, MO 10/10 Excellent "Yes everything was good" [](https://expedia.ca/Farmington-Hotels-Baymont-Inn-And-Suites-By-Wyndham-Farmington.h16153.Hotel-Information) ![Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG](//images.trvl-media.com/lodging/3000000/2700000/2699400/2699317/720261dc_y.jpg) ### Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG 10/10 Excellent "The workers kept the food area and tables clean" [](https://expedia.ca/Farmington-Hotels-Holiday-Inn-Express-Hotel-Suites-FESTUS-SOUTH-ST-LOUIS.h2699317.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Festus - St. Louis South](//images.trvl-media.com/lodging/1000000/50000/42200/42120/1887aa70_y.jpg) ### La Quinta Inn & Suites by Wyndham Festus - St. Louis South 10/10 Excellent "Breakfast had hot and cold choices. Great guy taking care of the pantry. Staff was friendly, room was clean and heat and air conditioning worked fine. Good selection of tv shows to watch." [](https://expedia.ca/Farmington-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Festus-St-Louis-South.h42120.Hotel-Information) ![Secluded cabin on private property](//images.trvl-media.com/lodging/90000000/89990000/89989800/89989748/b82525ba_y.jpg) ### Secluded cabin on private property 10/10 Excellent "Went for a weekend to get away from the city. The cabin is located on a beautiful piece of property. Even though you are deep in the woods, we felt completely safe. The cabin is very spacious and offers the same amenities you would find in a hotel. White linens, modern kitchen, everything you need to cook your own meals and extremely comfortable beds. We purchased everything we needed to make our dinner at the DeSoto farmers market and we brought our projector from home and watched movies on the ceiling. It was the perfect getaway. We hope to make it back again for a longer visit. The owners were incredibly polite and quick with responses. " [](https://expedia.ca/De-Soto-Hotels-Secluded-Cabin-On-Private-Property.h89989748.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [5 Star Hotels in Herculaneum](https://www.expedia.ca/5Star-Herculaneum-Hotels.s50-0-d3000349395.Travel-Guide-Filter-Hotels) - [Aparthotels in Barnhart](https://www.expedia.ca/Barnhart-Apart-Hotels.d6354572-aaApartHotels.Travel-Guide-Accommodation) - [Cheap Hotels in Barnhart](https://www.expedia.ca/Barnhart-Hotels-Cheap-Hotels.0-0-d6354572-tCheapHotels.Travel-Guide-Filter-Hotels) - [Barnhart Hotels](https://www.expedia.ca/Barnhart-Hotels.d6354572.Travel-Guide-Hotels) - [Townhomes in Barnhart](https://www.expedia.ca/Barnhart-Townhomes.d6354572-aaTownhomes.Travel-Guide-Accommodation) - [Farmstay in Bonne Terre](https://www.expedia.ca/Bonne-Terre-Agritourism.d55598-aaAgritourism.Travel-Guide-Accommodation) - [B&B in Bonne Terre](https://www.expedia.ca/Bonne-Terre-Bed-And-Breakfast.d55598-aaBedAndBreakfast.Travel-Guide-Accommodation) - 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