Title: 10 Best Hotels in Cherokee Seneca, Louisville for 2026 | Expedia.ca [Cherokee Seneca Travel Guide](https://expedia.ca/Louisville-Cherokee-Seneca.dx553248635976470112)[Vacation Rentals in Louisville](https://expedia.ca/Louisville-Vacation-Rentals.d603002.Travel-Guide-VacationRentals)[Flights to Louisville](https://expedia.ca/Cheap-Flights-To-Louisville.d603002.Travel-Guide-Flights)[Things to do in Louisville](https://expedia.ca/Things-To-Do-In-Louisville.d603002.Travel-Guide-Activities)[Cherokee Seneca Car Rentals](https://expedia.ca/Car-Rentals-In-Cherokee-Seneca.d553248635976470112.Car-Rental-Guide)[Cherokee Seneca Vacations](https://expedia.ca/Cherokee-Seneca.d553248635976470112.Destination-Travel-Guides) ![Lodging Image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Feb 1 - Feb 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976470112&startDate=2026-02-01&endDate=2026-02-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 2 - Feb 3](https://www.expedia.ca/Hotel-Search?regionId=553248635976470112&startDate=2026-02-02&endDate=2026-02-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=553248635976470112&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=553248635976470112&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Cherokee Seneca hotels ![3 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/54f0e03a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/bea44cd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/506c167d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/80fbdedc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Caesars Southern Indiana - A Caesars Rewards Destination [](https://www.expedia.ca/Elizabeth-Hotels-Caesars-Southern-Indiana.h795844.Hotel-Information) 20.2 km from Cherokee Seneca 8.2/10 Very good (1,001 reviews) "Great place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ismael [](https://www.expedia.ca/Elizabeth-Hotels-Caesars-Southern-Indiana.h795844.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/70000000/69270000/69261100/69261006/4b2caacc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/70000000/69270000/69261100/69261006/0d181aea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/70000000/69270000/69261100/69261006/9c87f224.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/70000000/69270000/69261100/69261006/w2667h3995x0y0-be0e3d23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Louisville Shepherdsville [](https://www.expedia.ca/Louisville-Hotels-Fairfield-Inn-Suites-By-Marriott-Louisville-Shepherdsville.h69261006.Hotel-Information) 19.2 km from Cherokee Seneca 9.4/10 Exceptional (422 reviews) "Excellent front desk staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cordell CA $146 CA $162 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Louisville-Hotels-Fairfield-Inn-Suites-By-Marriott-Louisville-Shepherdsville.h69261006.Hotel-Information) ![3 bars/lounges](https://images.trvl-media.com/lodging/94000000/93190000/93187900/93187879/fb60fb85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/94000000/93190000/93187900/93187879/w1008h540x16y0-17eab988.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges](https://images.trvl-media.com/lodging/94000000/93190000/93187900/93187879/8867b3d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch LCD TV with digital channels, TV, pay movies](https://images.trvl-media.com/lodging/94000000/93190000/93187900/93187879/ad4f836d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Derby City Gaming & Hotel - A Churchill Downs Property [](https://www.expedia.ca/Louisville-Hotels-Derby-City-Gaming-Hotel.h93187879.Hotel-Information) 6 km from Cherokee Seneca 9.4/10 Exceptional (1,789 reviews) "Rooms are very nice we had a great time " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) william CA $139 CA $163 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Louisville-Hotels-Derby-City-Gaming-Hotel.h93187879.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/30000000/29640000/29636600/29636519/4b2da9d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/30000000/29640000/29636600/29636519/5580fe14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/30000000/29640000/29636600/29636519/adee5a27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/30000000/29640000/29636600/29636519/f27f1b00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Shepherdsville Louisville South [](https://www.expedia.ca/Louisville-Hotels-Tru-By-Hilton-Shepherdsville-Louisville-South.h29636519.Hotel-Information) 19.1 km from Cherokee Seneca 9.2/10 Wonderful (862 reviews) "Very friendly staff, very clean and comfy rooms" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Trevor CA $131 CA $145 total includes taxes & fees Feb 20 - Feb 21 [](https://www.expedia.ca/Louisville-Hotels-Tru-By-Hilton-Shepherdsville-Louisville-South.h29636519.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2240000/2233300/2233230/w758h430x0y0-d45e9722.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2240000/2233300/2233230/54b88bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/3000000/2240000/2233300/2233230/4e8b1b48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2240000/2233300/2233230/68907abe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Shepherdsville Louisville South [](https://www.expedia.ca/Louisville-Hotels-Sleep-Inn-Suites-Shepherdsville-Louisville-South.h2233230.Hotel-Information) 27.9 km from Cherokee Seneca 8.4/10 Very good (750 reviews) "I liked most everything about this hotel. Nice friendly staff. Easy to access off the road. Clean rooms. Restaurants in the area. I would stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeff CA $122 CA $135 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Louisville-Hotels-Sleep-Inn-Suites-Shepherdsville-Louisville-South.h2233230.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/20000000/19430000/19423600/19423555/w4017h2675x0y0-6de349a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/20000000/19430000/19423600/19423555/78130bf4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/20000000/19430000/19423600/19423555/26adb915.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/20000000/19430000/19423600/19423555/679e1f17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Louisville Mall of St. Matthews [](https://www.expedia.ca/Louisville-Hotels-Hilton-Garden-Inn-Louisville-Mall-Of-St-Matthews.h19423555.Hotel-Information) St. Matthews, 5.2 km from Cherokee Seneca 9.2/10 Wonderful (896 reviews) "Great view, comfortably slept and amazing staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rebecca CA $130 CA $152 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Louisville-Hotels-Hilton-Garden-Inn-Louisville-Mall-Of-St-Matthews.h19423555.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42500/42421/f783b8aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42500/42421/w3840h2557x0y4-082574f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42500/42421/w3837h2558x3y3-8c0d9bd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (with Sofabed)](https://images.trvl-media.com/lodging/1000000/50000/42500/42421/w3837h2561x3y0-e5a94bd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Louisville South / Shepherdsville [](https://www.expedia.ca/Louisville-Hotels-Best-Western-Louisville-South-Shepherdsville.h42421.Hotel-Information) 19.1 km from Cherokee Seneca 8.6/10 Excellent (961 reviews) "Breakfast was good " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph CA $109 CA $121 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Louisville-Hotels-Best-Western-Louisville-South-Shepherdsville.h42421.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356812/w3836h2489x0y0-683f8c6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356812/02cb97ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356812/dcb9a5ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Refrigerator & Microwave](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356812/5371ada5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Simpsonville [](https://www.expedia.ca/Louisville-Hotels-Hampton-Inn-Simpsonville.h31356812.Hotel-Information) 29.6 km from Cherokee Seneca 9.4/10 Exceptional (912 reviews) "Would stay again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chris CA $122 CA $135 total includes taxes & fees Feb 7 - Feb 8 [](https://www.expedia.ca/Louisville-Hotels-Hampton-Inn-Simpsonville.h31356812.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1010000/1000800/1000719/dc95a9cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1010000/1000800/1000719/2829a9bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1010000/1000800/1000719/25c2a8c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, pillowtop beds, desk](https://images.trvl-media.com/lodging/2000000/1010000/1000800/1000719/7999cb57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wingate by Wyndham Louisville Fair and Expo [](https://www.expedia.ca/Louisville-Hotels-Wingate-By-Wyndham-Louisville-Fair-And-Expo.h1000719.Hotel-Information) 3.7 km from Cherokee Seneca 8.4/10 Very good (1,235 reviews) "Clean room, friendly staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Destiny CA $83 CA $97 total includes taxes & fees Mar 2 - Mar 3 [](https://www.expedia.ca/Louisville-Hotels-Wingate-By-Wyndham-Louisville-Fair-And-Expo.h1000719.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90160000/90153300/90153267/ab953f7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90160000/90153300/90153267/63f2377c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/91000000/90160000/90153300/90153267/6b43e534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90160000/90153300/90153267/205bcb1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites By Hilton Shepherdsville Louisville South [](https://www.expedia.ca/Louisville-Hotels-Home2-Suites-By-Hilton-Shepherdsville-Louisville-South.h90153267.Hotel-Information) 27.9 km from Cherokee Seneca 9.4/10 Exceptional (248 reviews) "Very clean comfortable room" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robby CA $144 CA $161 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Louisville-Hotels-Home2-Suites-By-Hilton-Shepherdsville-Louisville-South.h90153267.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1800000/1793700/1793667/47cd44d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1800000/1793700/1793667/005117d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1800000/1793700/1793667/0e0f3331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1800000/1793700/1793667/86e45de1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Springhill Suites by Marriott Louisville Airport [](https://www.expedia.ca/Louisville-Hotels-Springhill-Suites-By-Marriott-Louisville-Airport.h1793667.Hotel-Information) Fairgrounds, 7.1 km from Cherokee Seneca 8.8/10 Excellent (1,000 reviews) "Great location close to expo center. Friendly staff and nice breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Teresa CA $133 CA $157 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Louisville-Hotels-Springhill-Suites-By-Marriott-Louisville-Airport.h1793667.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/23000000/22820000/22819000/22818989/f8c825f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/23000000/22820000/22819000/22818989/75b15ec5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/23000000/22820000/22819000/22818989/a8205d18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/23000000/22820000/22819000/22818989/377181fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Louisville Northeast [](https://www.expedia.ca/Louisville-Hotels-Fairfield-Inn-Suites-By-Marriott-Louisville-Northeast.h22818989.Hotel-Information) 12.6 km from Cherokee Seneca 9.2/10 Wonderful (626 reviews) "Breakfast was good and staff was friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie CA $143 CA $168 total includes taxes & fees Feb 3 - Feb 4 [](https://www.expedia.ca/Louisville-Hotels-Fairfield-Inn-Suites-By-Marriott-Louisville-Northeast.h22818989.Hotel-Information) ![Suite, 1 King Bed with Sofa bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/2000000/1210000/1205100/1205024/8a3ae755.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1210000/1205100/1205024/19457055.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1210000/1205100/1205024/70fb7cbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1210000/1205100/1205024/48afd2ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Louisville Airport [](https://www.expedia.ca/Louisville-Hotels-Comfort-Suites-Airport.h1205024.Hotel-Information) 9.5 km from Cherokee Seneca 8.2/10 Very good (868 reviews) "Room was very nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shania CA $132 CA $155 total includes taxes & fees Feb 18 - Feb 19 [](https://www.expedia.ca/Louisville-Hotels-Comfort-Suites-Airport.h1205024.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/11400/11386/a27e575e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/1000000/20000/11400/11386/05d950ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11400/11386/d0b2a2a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/20000/11400/11386/1520df42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Crowne Plaza Louisville Airport Expo Ctr by IHG [](https://www.expedia.ca/Louisville-Hotels-Crowne-Plaza-Louisville-Airport-Expo-Center.h11386.Hotel-Information) Fairgrounds, 7 km from Cherokee Seneca 8.8/10 Excellent (1,135 reviews) "Great service and excellent accommodations!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Douglas CA $141 CA $166 total includes taxes & fees Mar 3 - Mar 4 [](https://www.expedia.ca/Louisville-Hotels-Crowne-Plaza-Louisville-Airport-Expo-Center.h11386.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/880000/874400/874388/9148c40a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/880000/874400/874388/a9cf031d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Multiple Beds](https://images.trvl-media.com/lodging/1000000/880000/874400/874388/6370cf00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/880000/874400/874388/266a3595.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Louisville Airport [](https://www.expedia.ca/Louisville-Hotels-Courtyard-By-Marriott-Louisville-Airport.h874388.Hotel-Information) 7.1 km from Cherokee Seneca 9.2/10 Wonderful (374 reviews) "Facilities were very clean and quiet. Easy drive to restaurants and the airport. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brandon CA $128 CA $151 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Louisville-Hotels-Courtyard-By-Marriott-Louisville-Airport.h874388.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/16100/16068/b29d262f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16100/16068/2c990f01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/16100/16068/8d7afd5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking, Microwave](https://images.trvl-media.com/lodging/1000000/20000/16100/16068/08d60bb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cottonwood Airport & Expo Hotel Louisville [](https://www.expedia.ca/Louisville-Hotels-Cottonwood-Airport-Expo-Hotel-Louisville.h16068.Hotel-Information) 12.2 km from Cherokee Seneca 8.6/10 Excellent (981 reviews) "The room was clean and staff were very friendly and helpful, but i do wish the restaurant and bar were open in the evenings. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jody CA $114 CA $135 total includes taxes & fees Feb 16 - Feb 17 [](https://www.expedia.ca/Louisville-Hotels-Cottonwood-Airport-Expo-Hotel-Louisville.h16068.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/80000/77800/77732/7fe09ae1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/80000/77800/77732/1b0c7b58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed](https://images.trvl-media.com/lodging/1000000/80000/77800/77732/e7db5ed1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/80000/77800/77732/e5893f09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Louisville Airport [](https://www.expedia.ca/Louisville-Hotels-Fairfield-Inn-Suites-By-Marriott-Louisville-Airport.h77732.Hotel-Information) 7.3 km from Cherokee Seneca 8.8/10 Excellent (692 reviews) "Clean comfortable room; friendly staff; so close to airport!! Perfect for our needs" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kandice CA $127 CA $149 total includes taxes & fees Feb 3 - Feb 4 [](https://www.expedia.ca/Louisville-Hotels-Fairfield-Inn-Suites-By-Marriott-Louisville-Airport.h77732.Hotel-Information) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/77000000/76420000/76418000/76417931/6d42a41f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/77000000/76420000/76418000/76417931/25d60e0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/77000000/76420000/76418000/76417931/1f121f2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/77000000/76420000/76418000/76417931/74f4d732.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Jeffersonville Louisville North [](https://www.expedia.ca/Louisville-Hotels-Hilton-Garden-Inn-Jeffersonville.h76417931.Hotel-Information) 12.2 km from Cherokee Seneca 9.6/10 Exceptional (438 reviews) "nice hotel, nice staff and bar." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) STEVEN CA $144 CA $163 total includes taxes & fees Feb 6 - Feb 7 [](https://www.expedia.ca/Louisville-Hotels-Hilton-Garden-Inn-Jeffersonville.h76417931.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/30000000/29640000/29637000/29636934/9a0e8ab8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/30000000/29640000/29637000/29636934/5fd359aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/30000000/29640000/29637000/29636934/200c79e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/30000000/29640000/29637000/29636934/a15d1f88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Louisville Airport [](https://www.expedia.ca/Louisville-Hotels-Tru-By-Hilton-Louisville-Airport.h29636934.Hotel-Information) Fairgrounds, 7.2 km from Cherokee Seneca 9.0/10 Wonderful (1,000 reviews) "The hotel was very clean the service was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Denise CA $127 CA $150 total includes taxes & fees Feb 16 - Feb 17 [](https://www.expedia.ca/Louisville-Hotels-Tru-By-Hilton-Louisville-Airport.h29636934.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1890000/1889100/1889073/205cbe4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1890000/1889100/1889073/9c58c339.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1890000/1889100/1889073/caf3983f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1890000/1889100/1889073/b81bbc64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Louisville Airport - Fair/Expo by IHG [](https://www.expedia.ca/Louisville-Hotels-Holiday-Inn-Louisville-Airport-FairExpo.h1889073.Hotel-Information) Fairgrounds, 7 km from Cherokee Seneca 8.2/10 Very good (988 reviews) "Staff was super friendly, hotel was clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer CA $105 CA $123 total includes taxes & fees Feb 3 - Feb 4 [](https://www.expedia.ca/Louisville-Hotels-Holiday-Inn-Louisville-Airport-FairExpo.h1889073.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-15&endDate=2026-02-16®ionId=553248635976470112&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in Cherokee Seneca Find the best Cherokee Seneca areas and neighborhoods for the activities you enjoy most. [Learn more about Cherokee Seneca](https://www.expedia.ca/Louisville-Cherokee-Seneca.dx553248635976470112) - Downtown Louisville - Fairgrounds - Old Louisville - Phoenix Hill - St. Matthews ![Louisville showing signage and street scenes as well as a small group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/297000/297251-Louisville-And-Vicinity.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Louisville which includes signage](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/297000/297227-Louisville-And-Vicinity.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Louisville featuring a city, outdoor art and a statue or sculpture](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/297000/297193-Kentucky.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Louisville which includes a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/297000/297238-Louisville-And-Vicinity.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Louisville showing a park](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/297000/297217-Louisville-And-Vicinity.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6059557) ![Downtown Louisville map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:kdmhFh%7CnjOapAwMw%40RhEoOt%40cRs%40ci%40oLmpAb%5Bcj%40xp%40lIjZ%7Ct%40yHzvBqDd_%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=FJLf3xbbARuVZOUjxQj9NS62D4M=) ### Downtown Louisville Explore "Museum Row" in the West Main District, catch a game at Louisville Slugger Field, or stroll across the pedestrian-only Big Four Bridge. Enjoy diverse attractions, restaurants, and the Louie Link skywalk. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6059557) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976386801) ![Fairgrounds map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:gcdhFfoljOe%5CaD%7E%40cQCmQiL%5EvBeIvAsVlBeKzSch%40%7EB%7BDxD%7BDfJqEjN_B%7EJmCx%5CoRGja%40nB%7E%7B%40oC%60c%40sGJsAyDlHeH%7EAsM%7BM_%5DsQnLlAfCcErBcCb%5EO%7CEzOHUvPz%40jJsk%40%7CJ&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=P2J5RkdzXJAsCNnGSZDarKegGk8=) ### Fairgrounds While visiting Fairgrounds, you might make a stop by sights like Freedom Hall and Kentucky Kingdom. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976386801) ![Conrad Caldwell House featuring heritage elements and signage](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/297000/297412-Conrad-Caldwell-House.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Conrad Caldwell House featuring a house and heritage architecture as well as a small group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/297000/297409-Conrad-Caldwell-House.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Conrad Caldwell House showing interior views, heritage elements and a house](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/297000/297419-Conrad-Caldwell-House.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Conrad Caldwell House featuring interior views and heritage elements](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/297000/297423-Conrad-Caldwell-House.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Conrad Caldwell House which includes wild flowers and heritage elements](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/297000/297425-Conrad-Caldwell-House.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6338738) ![Old Louisville map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:iilhFdlnjOoXq%40tHqjBh%60AdI%7EJyCrf%40zDjVoBnDj%40cArObYb%40eJnNaD%7Ef%40kNoBYvI%7Bj%40nQu%5C%7BJEyV%7BGwBg%60%40s%40uD%60i%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=8rx5MgdAm_BtIpBEAN5OekjdEWE=) ### Old Louisville Boasting Victorian architecture and the highest concentration of stained glass windows in residential homes, Old Louisville offers a walkable neighborhood with pedestrian-only streets, diverse dining options, and attractions like Central Park and the Conrad-Caldwell House. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6338738) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976384799) ![Phoenix Hill map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:gxlhF%60rjjOwi%40gFwAeEEeBrG%7DjAbAuAdk%40aa%40%60%40N%3FtHg%40xCsCl%7C%40LfFg%40fCsBjh%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=xzdTSnzeTGPVEx-dTDqM5wqU4yA=) ### Phoenix Hill While Phoenix Hill isn't home to many top sights, Nulu Market Place and Thomas Edison House are some notable places to visit nearby. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976384799) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=55484) ![St. Matthews map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:mnnhFdc%7BiObC_x%40oY%60TaHnG%7E%40%7EAuEvCcJyPOm%40bWuReJ%7DSkOlLiLqW_%40T_I%7BTtDiCfKwKfF%3FiQae%40iCkDcEcK%7CRoT%7CEtJ%60HwGzBnErN_NfKTl%5BxBFyAaAGlBsi%40g_%40sOoIkQiF%7CAqVbBoM%60CoNdF%7BNrIaLsW%7CXkUqLiVnRqPyCyG%7CEgEoHiQ%60BoB%7ECcBdKbS%7CB%7EGzGtNzLkJPzMvAtEiAvKh%40lAlIsHn%5C%7DVlFzL%60%40i%40iA%7DD%60Aw%40%60AjBnBd%40lAOtCpEd%40g%40h%40z%40xADmBlt%40j%40Fv%40%7DT%7EKvCB%60A%7C%5ChEtMdFdDbElShEfGCpYjj%40hTvg%40wFoAuDsC%7BAWiDj%40cE%7CC%7CAbDlBjB%60CeHz%40%3FzBfBjHdO%3FtCaHdGwC%7E%40cAvAu_%40jZv%40XhCvIt%40x%40SfJiVcAk%40iAeFpEn%40%7EAmMjLwHfF%60KbVgLlIgAkCwAbAg%40qAdAq%40%7DQib%40kEjDrRze%40uH%7CF%5Bq%40wP%7ELiE%7BOpAgAu%40qB_An%40k%40gBhByAeAkC%60BsA%7DEaMsAdA%7BAwD%7EI%7BG%7BAsDxDwC%7BAyDnJgHw%40qBdCmBy%40wBwJtHoCiGuFjEwAlYoAv%40LfLW%60LrBm%40%7C%40pDy%40l%40%3FtBrCwBnEdPa%40Ll%40bBd%40YbCnJuLxIk%40wA%7BHzE&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=MYTAqgfcWp7dwDhfwYURgZj4N7E=) ### St. Matthews Major shopping destination with the fifth-largest mall in Kentucky, Mall St. Matthews, and smaller centers along Shelbyville Road. Don't miss the historic St. Matthew's Episcopal Church and Holy Trinity. [See properties](https://www.expedia.ca/Hotel-Search?regionId=55484) ## Top Cherokee Seneca Hotel Reviews ![Omni Louisville Hotel](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/4c7c479b_y.jpg) ### Omni Louisville Hotel 10/10 Excellent "Excellent location, unique common areas, good food and plenty to experience without leaving the hotel. Library bar, speak easy, two restaurants and attached marketplace offers a wide variety. Staff are friendly. Rooms clean and spacious. Highly recommend. " [](https://expedia.ca/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information) ![Derby City Gaming & Hotel - A Churchill Downs Property ](https://images.trvl-media.com/lodging/94000000/93190000/93187900/93187879/ee0d92e3_y.jpg) ### Derby City Gaming & Hotel - A Churchill Downs Property 10/10 Excellent "New and clean " [](https://expedia.ca/Louisville-Hotels-Derby-City-Gaming-Hotel.h93187879.Hotel-Information) ![Towneplace Suites By Marriott Louisville Downtown](https://images.trvl-media.com/lodging/65000000/64700000/64696100/64696084/8f8322e9_y.jpg) ### Towneplace Suites By Marriott Louisville Downtown 10/10 Excellent "staff was great, room was beautiful!!! and so clean. great stay would definitely choose you all again!" [](https://expedia.ca/Louisville-Hotels-Towneplace-Suites-By-Marriott-Louisville-Downtown.h64696084.Hotel-Information) ![Homewood Suites by Hilton Louisville Downtown, KY](https://images.trvl-media.com/lodging/22000000/21600000/21599900/21599840/5c04f012_y.jpg) ### Homewood Suites by Hilton Louisville Downtown, KY 10/10 Excellent "good time nice room" [](https://expedia.ca/Louisville-Hotels-Homewood-Suites-By-Hilton-Louisville-Downtown.h21599840.Hotel-Information) ![The Brown Hotel](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/840e31de_y.jpg) ### The Brown Hotel 10/10 Excellent "Beautiful hotel and wonderful staff, got us through an extended stay due to snowstorm. Highly recommend!" [](https://expedia.ca/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information) ![Embassy Suites Louisville Downtown](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/e02820b0_y.jpg) ### Embassy Suites Louisville Downtown 10/10 Excellent "Everything.... Really enjoyed this place and we will stay here again can't wait!!!" [](https://expedia.ca/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information) ![Home2 Suites by Hilton Louisville Downtown NuLu](https://images.trvl-media.com/lodging/20000000/19780000/19771000/19770976/51139f76_y.jpg) ### Home2 Suites by Hilton Louisville Downtown NuLu 10/10 Excellent "Very nice hotel and.accommodations! Great breakfast too! " [](https://expedia.ca/Louisville-Hotels-Home2-Suites-By-Hilton-Louisville-Downtown-NuLu.h19770976.Hotel-Information) ![Crowne Plaza Louisville Airport Expo Ctr by IHG](https://images.trvl-media.com/lodging/1000000/20000/11400/11386/a43a56f2_y.jpg) ### Crowne Plaza Louisville Airport Expo Ctr by IHG 10/10 Excellent "Awesoem" [](https://expedia.ca/Louisville-Hotels-Crowne-Plaza-Louisville-Airport-Expo-Center.h11386.Hotel-Information) ![Radisson Hotel Louisville North](https://images.trvl-media.com/lodging/1000000/30000/26400/26306/50b82654_y.jpg) ### Radisson Hotel Louisville North 10/10 Excellent "The staff is very welcoming and friendly. Such a pleasant check in experience. Ample parking so I was able to park close to the nearest entry closest to my room. Plenty of amenities on site as well as nearby. The room was provided with plenty of towels and washcloths as well as pillows for the bed. Overall, an enjoyable stay and highly recommended. " [](https://expedia.ca/Louisville-Hotels-Radisson-Hotel-Louisville-North.h26306.Hotel-Information) ## Frequently asked questions ### What is Cherokee Seneca like? ### If I need to cancel my hotel reservation in Cherokee Seneca, will I receive a refund? ### What is there to do around this Louisville neighborhood? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [5 Star Hotels in Rockcreek Lexington Road ](https://www.expedia.ca/5Star-Rockcreek-Lexington-Road-Louisville-Hotels.s50-n553248635976394488-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Strathmoor Manor ](https://www.expedia.ca/5Star-Strathmoor-Manor-Louisville-Hotels.s50-n553248634998690861-0.Travel-Guide-Filter-Hotels) - [Audubon Hotels ](https://www.expedia.ca/Audubon-Louisville-Hotels.0-n553248635976470213-0.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Avondale Melbourne Heights ](https://www.expedia.ca/Avondale-Melbourne-Heights-Louisville-Hotels-Luxury-Hotel.0-n553248635976469784-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - 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