Find LGBTQ welcoming hotels in Cape Girardeau, MO

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Top Cape Girardeau LGBT Friendly Hotels

Drury Plaza Hotel Cape Girardeau Conference Center
3 out of 5
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is CA $125 per night from Aug 25 to Aug 26
CA $125
CA $141 total
Aug 25 - Aug 26
includes taxes & fees
9.4/10 Exceptional! (1,003 reviews)
"Excellent Check in was amazing. Lady at the counter was very patient and very helpful"

Reviewed on Aug. 18, 2025

Drury Plaza Hotel Cape Girardeau Conference Center
Pear Tree Inn Cape Girardeau West
2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is CA $97 per night from Aug 24 to Aug 25
CA $97
CA $109 total
Aug 24 - Aug 25
includes taxes & fees
9/10 Wonderful! (1,000 reviews)
"Ok hotel. Good for a single night stop over. Next to outback."

Reviewed on Aug. 17, 2025

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 out of 5
3248 William St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is CA $97 per night from Aug 24 to Aug 25
CA $97
CA $109 total
Aug 24 - Aug 25
includes taxes & fees
8.8/10 Excellent! (1,002 reviews)
The go to!
"Always friendly and clean. My go to in the Cape!"

Reviewed on Aug. 13, 2025

Pear Tree Inn Cape Girardeau Near the Medical Center
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Courtyard by Marriott Cape Girardeau Downtown
3 out of 5
400 Broadway St., Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is CA $173 per night from Aug 31 to Sep 1
CA $173
CA $196 total
Aug 31 - Sep 1
includes taxes & fees
9.4/10 Exceptional! (439 reviews)
"Early morning delivery trucks"

Reviewed on Aug. 18, 2025

Courtyard by Marriott Cape Girardeau Downtown
Drury Inn & Suites Cape Girardeau
3 out of 5
3303 Campster Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is CA $125 per night from Aug 31 to Sep 1
CA $125
CA $141 total
Aug 31 - Sep 1
includes taxes & fees
9.2/10 Wonderful! (981 reviews)
"Everything was nice until we checked out and he asked for a receipt and upon looking at our receipt, we had two charges from the pantry that we did not get so someone allowed someone to use our room to get free food and we not asked for a receipt we would have never know so I think it needs to be ..."

Reviewed on Aug. 16, 2025

Drury Inn & Suites Cape Girardeau
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 out of 5
3253 William Street, Cape Girardeau, MO
Fully refundable
The price is CA $143 per night from Sep 1 to Sep 2
CA $143
CA $161 total
Sep 1 - Sep 2
includes taxes & fees
9.4/10 Exceptional! (1,003 reviews)
"It was great had a wonderful time with my in-laws."

Reviewed on Aug. 17, 2025

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Hampton Inn Cape Girardeau I 55 East
2.5 out of 5
207 S Mt Auburn Rd, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is CA $152 per night from Aug 31 to Sep 1
CA $152
CA $172 total
Aug 31 - Sep 1
includes taxes & fees
9.6/10 Exceptional! (739 reviews)
"Nice and clean hotel friendly service"

Reviewed on Aug. 15, 2025

Hampton Inn Cape Girardeau I 55 East
Candlewood Suites Cape Girardeau by IHG
2.5 out of 5
485 S Mount Auburn Rd, Cape Girardeau, MO
Fully refundable
The price is CA $97 per night from Aug 24 to Aug 25
CA $97
CA $117 total
Aug 24 - Aug 25
includes taxes & fees
8/10 Very Good! (837 reviews)
"The whole stay was great from customer service to cleanliness, quality and comfort."

Reviewed on Aug. 14, 2025

Candlewood Suites Cape Girardeau by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the top gay-friendly hotels in Cape Girardeau


Are gay-friendly hotels in Cape Girardeau available?


Yes, Cape Girardeau gay-friendly hotels are available in abundance throughout the area. These hotels come in a wide variety of configurations as well, allowing you to customize your vacation whether you're looking for something budget-friendly or something more luxurious. Room configurations, amenities, styles and more can all be customized as you see fit based on the kind of vacation experience you're looking for. Plus, these hotels have strict policies against discrimination and typically are in the know regarding the best LGBTQ-friendly activities in town.



How can I find the best gay-friendly hotels in Cape Girardeau?


Finding Cape Girardeau gay-friendly hotels is easy, thanks to our search filters. You'll find a massive array of filters, so you can sort your results to only show hotels that cater specifically to your desired vacation experience. You can implement filters for amenities in your hotel as well as for star ratings and guest reviews. You'll even find filters for price, so you can limit your results to only show hotels that are within your established budget. Additionally, you'll find a filter for LGBTQ-friendly hotels, so be sure to activate that one to sort all the non-accommodating hotels out of your search results.



How can I find top deals on gay-friendly hotels in Cape Girardeau?


To find deals, you'll want to take advantage of the various factors that affect hotel prices. These include the time of year, amenities, neighbourhood and more. Travelling during the off-season can net you lower prices, as can relinquishing amenities like spas and hot tubs. Additionally, booking outside of town can be cheaper than putting yourself right in the middle of the action. Don't forget to sort your search results by price as well to see the cheapest options for your hotel first. Gay-friendly hotels in Cape Girardeau have fluctuating prices, so it's important to remember that these are more general trends than rules set in stone.



Why should I book Cape Girardeau gay-friendly hotels with Expedia?


Booking with Expedia is among the easiest ways to ensure all your travel planning can be taken care of in a single, convenient place. Not only will you find an array of gay-friendly hotels in Cape Girardeau to choose from, but you'll find flights as well. The extensive search filters make finding the ultimate accommodation simple, as you can narrow down your search results to show only the hotels that fit your strict specifications. Plus, you can enjoy the Expedia Rewards program, which lets you earn points every time you book. Those points can be redeemed for discounts on future bookings, but that's just the beginning. Some accommodation options have special discounts only available to members. Becoming a member is free, so don't hesitate to take advantage.